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Volumn 181, Issue 2, 2008, Pages 1307-1314

Two loci on chromosome 15 control experimentally induced arthritis through the differential regulation of IL-6 and lymphocyte proliferation

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; PROTEOGLYCAN; TUMOR NECROSIS FACTOR ALPHA;

EID: 49049106180     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.2.1307     Document Type: Article
Times cited : (8)

References (50)
  • 8
    • 0035444186 scopus 로고    scopus 로고
    • High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis
    • Barton, A., S. Eyre, A. Myerscough, B. Brintnell, D. Ward, W. E. Ollier, J. C. Lorentzen, L. Klareskog, A. Silman, S. John, and J. Worthington. 2001. High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis. Hum. Mol. Genet. 10: 1901-1906. (Pubitemid 32910534)
    • (2001) Human Molecular Genetics , vol.10 , Issue.18 , pp. 1901-1906
    • Barton, A.1    Eyre, S.2    Myerscough, A.3    Brintnell, B.4    Ward, D.5    Ollier, W.E.R.6    Lorentzen, J.C.7    Klareskog, L.8    Silman, A.9    John, S.10    Worthington, J.11
  • 10
    • 31544455037 scopus 로고    scopus 로고
    • Genome scan meta-analysis of rheumatoid arthritis
    • DOI 10.1093/rheumatology/kei128
    • Choi, S. J., Y. H. Rho, J. D. Ji, G. G. Song, and Y. H. Lee. 2006. Genome scan meta-analysis of rheumatoid arthritis. Rheumatology 45: 166-170. (Pubitemid 43160077)
    • (2006) Rheumatology , vol.45 , Issue.2 , pp. 166-170
    • Choi, S.J.1    Rho, Y.H.2    Ji, J.D.3    Song, G.G.4    Lee, Y.H.5
  • 11
    • 0023254937 scopus 로고
    • Proteoglycaninduced arthritis in BALB/c mice. Clinical features and histopathology
    • Glant, T. T., K. Mikecz, A. Arzoumanian, and A. R. Poole. 1987. Proteoglycaninduced arthritis in BALB/c mice. Clinical features and histopathology. Arthritis Rheum. 30: 201-212.
    • (1987) Arthritis Rheum. , vol.30 , pp. 201-212
    • Glant, T.T.1    Mikecz, K.2    Arzoumanian, A.3    Poole, A.R.4
  • 12
    • 0141564778 scopus 로고    scopus 로고
    • Proteoglycan-induced arthritis: Immune regulation, cellular mechanisms, and genetics
    • DOI 10.1615/CritRevImmunol.v23.i3.20
    • Glant, T. T., A. Finnegan, and K. Mikecz. 2003. Proteoglycan-induced arthritis: immune regulation, cellular mechanisms and genetics. Crit. Rev. Immunol. 23: 199-250. (Pubitemid 37204432)
    • (2003) Critical Reviews in Immunology , vol.23 , Issue.3 , pp. 199-250
    • Glant, T.T.1    Finnegan, A.2    Mikecz, K.3
  • 13
    • 0034327208 scopus 로고    scopus 로고
    • A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis
    • Otto, J. M., R. Chandrasekaran, C. Vermes, K. Mikecz, A. Finnegan, S. E. Rickert, J. T. Enders, and T. T. Glant. 2000. A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis. J. Immunol. 165: 5278-5286.
    • (2000) J. Immunol. , vol.165 , pp. 5278-5286
    • Otto, J.M.1    Chandrasekaran, R.2    Vermes, C.3    Mikecz, K.4    Finnegan, A.5    Rickert, S.E.6    Enders, J.T.7    Glant, T.T.8
  • 15
    • 0018920615 scopus 로고
    • The epidemiology of rheumatoid arthritis in Rochester, Minnesota: A study of incidence, prevalence, and mortality
    • Linos, A., J. W. Worthington, W. M. O'Fallon, and L. T. Kurland. 1980. The epidemiology of rheumatoid arthritis in Rochester, Minnesota: a study of incidence, prevalence, and mortality. Am.J. Epidemiol. 111: 87-98. (Pubitemid 10207608)
    • (1980) American Journal of Epidemiology , vol.111 , Issue.1 , pp. 87-98
    • Linos, A.1    Worthington, J.W.2    O'Fallon, W.M.3    Kurland, L.T.4
  • 16
    • 0031958275 scopus 로고    scopus 로고
    • The influence of sex on the phenotype of rheumatoid arthritis
    • DOI 10.1002/1529-0131(199805)41:5<817::AID-ART7>3.0.CO;2-S
    • Weyand, C. M., D. Schmidt, U. Wagner, and J. J. Goronzy. 1998. The influence of sex on the phenotype of rheumatoid arthritis. Arthritis Rheum. 41: 817-822. (Pubitemid 28225781)
    • (1998) Arthritis and Rheumatism , vol.41 , Issue.5 , pp. 817-822
    • Weyand, C.M.1    Schmidt, D.2    Wagner, U.3    Goronzy, J.J.4
  • 17
    • 17444377878 scopus 로고    scopus 로고
    • Identification of a new non-major histocompatibility complex genetic locus on chromosome 2 that controls disease severity in collagen-induced arthritis in rats
    • Gulko, P. S., Y. Kawahito, E. F. Remmers, V. R. Reese, J. P. Wang, S. V. Dracheva, L. Ge, R. E. Longman, J. S. Shepard, G. W. Cannon, et al. 1998. Identification of a new non-major histocompatibility complex genetic locus on chromosome 2 that controls disease severity in collagen-induced arthritis in rats. Arthritis Rheum. 41: 2122-2131.
    • (1998) Arthritis Rheum. , vol.41 , pp. 2122-2131
    • Gulko, P.S.1    Kawahito, Y.2    Remmers, E.F.3    Reese, V.R.4    Wang, J.P.5    Dracheva, S.V.6    Ge, L.7    Longman, R.E.8    Shepard, J.S.9    Cannon, G.W.10
  • 18
    • 0033816349 scopus 로고    scopus 로고
    • Genetic dissection of collagen-induced arthritis in chromosome 10 quantitative trait locus speed congenic rats: Evidence for more than one regulatory locus and sex influences
    • DOI 10.1007/s002510000231
    • Joe, B., E. F. Remmers, D. E. Dobbins, J. L. Salstrom, T. Furuya, S. Dracheva, P. S. Gulko, G. W. Cannon, M. M. Griffiths, and R. L. Wilder. 2000. Genetic dissection of collagen-induced arthritis in chromosome 10 quantitative trait locus speed congenic rats: evidence for more than one regulatory locus and sex influences. Immunogenetics 51: 930-944. (Pubitemid 30696181)
    • (2000) Immunogenetics , vol.51 , Issue.11 , pp. 930-944
    • Joe, B.1    Remmers, E.F.2    Dobbins, D.E.3    Salstrom, J.L.4    Furuya, T.5    Dracheva, S.6    Gulko, P.S.7    Cannon, G.W.8    Griffiths, M.M.9    Wilder, R.L.10
  • 19
    • 0035869207 scopus 로고    scopus 로고
    • Rats made congenic for Oia3 on chromosome 10 become susceptible to squalene-induced arthritis
    • Holm, B. C., X. Wei, L. Jacobsson, A. Larsson, H. Luthman, and J. C. Lorentzen. 2001. Rats made congenic for Oia3 on chromosome 10 become susceptible to squalene-induced arthritis. Hum. Mol. Genet. 10: 565-572.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 565-572
    • Holm, B.C.1    Wei, X.2    Jacobsson, L.3    Larsson, A.4    Luthman, H.5    Lorentzen, J.C.6
  • 21
    • 0036222782 scopus 로고    scopus 로고
    • Evaluation of quantitative trait loci regulating severity of mycobacterial adjuvant-induced arthritis in monocongenic and polycongenic rats: Identification of a new regulatory locus on rat chromosome 10 and evidence of overlap with rheumatoid arthritis susceptibility loci
    • DOI 10.1002/art.10164
    • Joe, B., G. W. Cannon, M. M. Griffiths, D. E. Dobbins, P. S. Gulko, R. L. Wilder, and E. F. Remmers. 2002. Evaluation of quantitative trait loci regulating severity of mycobacterial adjuvant-induced arthritis in monocongenic and polycongenic rats: identification of a new regulatory locus on rat chromosome 10 and evidence of overlap with rheumatoid arthritis susceptibility loci. Arthritis Rheum. 46: 1075-1085. (Pubitemid 34303822)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.4 , pp. 1075-1085
    • Joe, B.1    Cannon, G.W.2    Griffiths, M.M.3    Dobbins, D.E.4    Gulko, P.S.5    Wilder, R.L.6    Remmers, E.F.7
  • 25
    • 0030659604 scopus 로고    scopus 로고
    • Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains
    • DOI 10.1038/ng1197-280
    • Markel, P., P. Shu, C. Ebeling, G. A. Carlson, D. L. Nagle, J. S. Smutko, and K. J. Moore. 1997. Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains. Nat. Genet. 17: 280-284. (Pubitemid 27475989)
    • (1997) Nature Genetics , vol.17 , Issue.3 , pp. 280-284
    • Markel, P.1    Shu, P.2    Ebeling, C.3    Carlson, G.A.4    Nagle, D.L.5    Smutko, J.S.6    Moore, K.J.7
  • 26
    • 0035164656 scopus 로고    scopus 로고
    • Map Manager QTX, cross-platform software for genetic mapping
    • Manly, K. F., R. H. Cudmore, Jr., and J. M. Meer. 2001. Map Manager QTX, cross-platform software for genetic mapping. Mamm. Genome 12: 930-932.
    • (2001) Mamm. Genome , vol.12 , pp. 930-932
    • Manly, K.F.1    Cudmore Jr., R.H.2    Meer, J.M.3
  • 27
    • 16644373165 scopus 로고    scopus 로고
    • Proteoglycan aggrecan-induced arthritis: A murine autoimmune model of rheumatoid arthritis
    • Glant, T. T., and K. Mikecz. 2004. Proteoglycan aggrecan-induced arthritis: a murine autoimmune model of rheumatoid arthritis. Methods Mol. Med. 102: 313-338.
    • (2004) Methods Mol. Med. , vol.102 , pp. 313-338
    • Glant, T.T.1    Mikecz, K.2
  • 28
    • 2342497178 scopus 로고    scopus 로고
    • Achievement of a Synergistic Adjuvant Effect on Arthritis Induction by Activation of Innate Immunity and Forcing the Immune Response Toward the Th1 Phenotype
    • DOI 10.1002/art.20180
    • Hanyecz, A., S. E. Berlo, S. Szanto, C. P. M. Broeren, K. Mikecz, and T. T. Glant. 2004. Achievement of a synergistic adjuvant effect on arthritis induction by activation of innate immunity and forcing the immune response toward the Th1 phenotype. Arthritis Rheum. 50: 1665-1676. (Pubitemid 38608090)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.5 , pp. 1665-1676
    • Hanyecz, A.1    Berlo, S.E.2    Szanto, S.3    Broeren, C.P.M.4    Mikecz, K.5    Glant, T.T.6
  • 29
    • 0036089570 scopus 로고    scopus 로고
    • Major histocompatibility complex controls susceptibility and dominant inheritance, but not the severity of the disease in mouse models of rheumatoid arthritis
    • Adarichev, V. A., T. Bardos, S. Christodoulou, M. T. Phillips, K. Mikecz, and T. T. Glant. 2002. Major histocompatibility complex controls susceptibility and dominant inheritance, but not the severity of the disease in mouse models of rheumatoid arthritis. Immunogenetics 54: 184-192.
    • (2002) Immunogenetics , vol.54 , pp. 184-192
    • Adarichev, V.A.1    Bardos, T.2    Christodoulou, S.3    Phillips, M.T.4    Mikecz, K.5    Glant, T.T.6
  • 30
    • 0033499482 scopus 로고    scopus 로고
    • Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis
    • Otto, J. M., G. Cs-Szabo, J. Gallagher, S. Velins, K. Mikecz, E. I. Buzas, J. T. Enders, Y. Li, B. R. Olsen, and T. T. Glant. 1999. Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis. Arthritis Rheum. 42: 2524-2531.
    • (1999) Arthritis Rheum. , vol.42 , pp. 2524-2531
    • Otto, J.M.1    Cs-Szabo, G.2    Gallagher, J.3    Velins, S.4    Mikecz, K.5    Buzas, E.I.6    Enders, J.T.7    Li, Y.8    Olsen, B.R.9    Glant, T.T.10
  • 31
    • 0031975307 scopus 로고    scopus 로고
    • Experimental strategies for the genetic dissection of complex traits in animal models
    • DOI 10.1038/ng0198-19
    • Darvasi, A. 1998. Experimental strategies for the genetic dissection of complex traits in animal models. Nat. Genet. 18: 19-24. (Pubitemid 28027873)
    • (1998) Nature Genetics , vol.18 , Issue.1 , pp. 19-24
    • Darvasi, A.1
  • 32
    • 0037371112 scopus 로고    scopus 로고
    • Combined autoimmune models of arthritis reveal shared and independent qualitative (binary) and quantitative trait loci
    • Adarichev, V. A., J. C. Valdez, T. Bardos, A. Finnegan, K. Mikecz, and T. T. Glant. 2003. Combined autoimmune models of arthritis reveal shared and independent qualitative (binary) and quantitative trait loci. J. Immunol. 170: 2283-2292.
    • (2003) J. Immunol. , vol.170 , pp. 2283-2292
    • Adarichev, V.A.1    Valdez, J.C.2    Bardos, T.3    Finnegan, A.4    Mikecz, K.5    Glant, T.T.6
  • 33
    • 33748117796 scopus 로고    scopus 로고
    • Interleukin-6: Discovery of a pleiotropic cytokine
    • Kishimoto, T. 2006. Interleukin-6: discovery of a pleiotropic cytokine. Arthritis Res. Ther. 8 (Suppl. 2): S2.
    • (2006) Arthritis Res. Ther. , vol.8 , Issue.SUPPL. 2
    • Kishimoto, T.1
  • 35
    • 0037474320 scopus 로고    scopus 로고
    • JAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of Sox9 expression
    • DOI 10.1074/jbc.M110773200
    • Legendre, F., J. Dudhia, J. P. Pujol, and P. Bogdanowicz. 2002. JAK/STAT but not ERK1/ERK2 pathway mediates IL-6/sIL-6R down-regulation of type II collagen, aggrecan core and link protein transcription in articular chondrocytes: association with a down-regulation of SOX9 expression. J. Biol. Chem. 278: 2903-2912. (Pubitemid 36801195)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.5 , pp. 2903-2912
    • Legendre, F.1    Dudhia, J.2    Pujol, J.-P.3    Bogdanowicz, P.4
  • 36
    • 0037265995 scopus 로고    scopus 로고
    • Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism
    • DOI 10.1016/S8756-3282(02)00915-8
    • Kudo, O., A. Sabokbar, A. Pocock, I. Itonaga, Y. Fujikawa, and N. A. Athanasou. 2003. Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism. Bone 32: 1-7. (Pubitemid 36173806)
    • (2003) Bone , vol.32 , Issue.1 , pp. 1-7
    • Kudo, O.1    Sabokbar, A.2    Pocock, A.3    Itonaga, I.4    Fujikawa, Y.5    Athanasou, N.A.6
  • 37
    • 85036818344 scopus 로고    scopus 로고
    • Gene expression profiling in murine adoptively transferred arthritis: Interaction of innate and adaptive immunity
    • Adarichev, V. A., C. Vermes, A. Hanyecz, E. Bremer, and T. T. Glant. 2004. Gene expression profiling in murine adoptively transferred arthritis: interaction of innate and adaptive immunity. Arthritis Rheum. 50: S122-S123.
    • (2004) Arthritis Rheum. , vol.50
    • Adarichev, V.A.1    Vermes, C.2    Hanyecz, A.3    Bremer, E.4    Glant, T.T.5
  • 38
    • 35948968392 scopus 로고    scopus 로고
    • A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity
    • Olsson, L. M., A. K. Lindqvist, H. Kallberg, L. Padyukov, H. Burkhardt, L. Alfredsson, L. Klareskog, and R. Holmdahl. 2007. A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity. Arthritis Res. Ther. 9: R98.
    • (2007) Arthritis Res. Ther. , vol.9
    • Olsson, L.M.1    Lindqvist, A.K.2    Kallberg, H.3    Padyukov, L.4    Burkhardt, H.5    Alfredsson, L.6    Klareskog, L.7    Holmdahl, R.8
  • 40
    • 0037224772 scopus 로고    scopus 로고
    • Positional identification of Ncf1 as a gene that regulates arthritis severity in rats
    • DOI 10.1038/ng1058
    • Olofsson, P., J. Holmberg, J. Tordsson, S. Lu, B. Akerstrom, and R. Holmdahl. 2003. Positional identification of Ncf1 as a gene that regulates arthritis severity in rats. Nat. Genet. 33: 25-32. (Pubitemid 36068678)
    • (2003) Nature Genetics , vol.33 , Issue.1 , pp. 25-32
    • Olofsson, P.1    Holmberg, J.2    Tordsson, J.3    Lu, S.4    Akerstrom, B.5    Holmdahl, R.6
  • 43
    • 1842612108 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts
    • Samper, E., D. G. Nicholls, and S. Melov. 2003. Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts. Aging Cell 2: 277-285.
    • (2003) Aging Cell , vol.2 , pp. 277-285
    • Samper, E.1    Nicholls, D.G.2    Melov, S.3
  • 44
    • 33744516058 scopus 로고    scopus 로고
    • TNFα induces chromosomal abnormalities independent of ROS through IKK, JNK, p38 and caspase pathways
    • DOI 10.1016/j.cyto.2006.03.015, PII S1043466606001335
    • Higashimoto, T., A. Panopoulos, C. L. Hsieh, and E. Zandi. 2006. TNFα induces chromosomal abnormalities independent of ROS through IKK, JNK, p38 and caspase pathways. Cytokine 34: 39-50. (Pubitemid 43817551)
    • (2006) Cytokine , vol.34 , Issue.1-2 , pp. 39-50
    • Higashimoto, T.1    Panopoulos, A.2    Hsieh, C.-L.3    Zandi, E.4
  • 45
    • 0038336667 scopus 로고    scopus 로고
    • Neoplastic development in plasma cells
    • Potter, M. 2003. Neoplastic development in plasma cells. Immunol. Rev. 194: 177-195.
    • (2003) Immunol. Rev. , vol.194 , pp. 177-195
    • Potter, M.1
  • 46
    • 0019465754 scopus 로고
    • Genetics of susceptibility to pristane-induced plasmacytomas in BALB/cAn: Reduced susceptibility in BALB/cJ with a brief description of pristane-induced arthritis
    • Potter, M., and J. S. Wax. 1981. Genetics of susceptibility to pristane-induced plasmacytomas in BALB/cAn: reduced susceptibility in BALB/cJ with a brief description of pristane-induced arthritis. J. Immunol. 127: 1591-1595. (Pubitemid 11021050)
    • (1981) Journal of Immunology , vol.127 , Issue.4 , pp. 1591-1595
    • Potter, M.1    Wax, J.S.2
  • 47
    • 67651211098 scopus 로고    scopus 로고
    • Genome scan for arthritis genes revealed significant chromosome locus-locus interation in mouse proteoglycan-induced arthritis
    • Adarichev, V. A., A. B. Nesterovitch, D. C. Biesczat, and T. T. Glant. 2003. Genome scan for arthritis genes revealed significant chromosome locus-locus interation in mouse proteoglycan-induced arthritis. Arthritis Rheum. 48: S229.
    • (2003) Arthritis Rheum. , vol.48
    • Adarichev, V.A.1    Nesterovitch, A.B.2    Biesczat, D.C.3    Glant, T.T.4
  • 50
    • 25444441987 scopus 로고    scopus 로고
    • Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation
    • Adarichev, V. A., C. Vermes, A. Hanyecz, K. Mikecz, E. Bremer, and T. T. Glant. 2005. Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation. Arthritis Res. Ther. 7: R196-R207.
    • (2005) Arthritis Res. Ther. , vol.7
    • Adarichev, V.A.1    Vermes, C.2    Hanyecz, A.3    Mikecz, K.4    Bremer, E.5    Glant, T.T.6


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