Testing causality in the association between regular exercise and symptoms of anxiety and depression

Archives of General Psychiatry

Volumn 65, Issue 8, 2008, Pages 897-905

  De Moor, Marleen H M ^a   Boomsma, Dorret I ^a   Stubbe, Janine H ^a   Willemsen, Gonneke ^a   De Geus, Eco J C ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANXIETY; ARTICLE; BIVARIATE ANALYSIS; CONTROLLED STUDY; DEPRESSION; EXERCISE; FAMILY; FEMALE; GENETIC CORRELATION; GENETIC MODEL; HEREDITY; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MONOZYGOTIC TWINS; NETHERLANDS; OUTCOME ASSESSMENT; PARENT; PREDICTION; RATING SCALE; SCORING SYSTEM; SIBLING; SYMPTOM;

ADULT; ANXIETY DISORDERS; CAUSALITY; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASES IN TWINS; EXERCISE; FEMALE; HUMANS; LEISURE ACTIVITIES; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NETHERLANDS; PERSONALITY INVENTORY; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 48949099981     PISSN: 0003990X     EISSN: 15383636     Source Type: Journal    
DOI: 10.1001/archpsyc.65.8.897     Document Type: Article

References (55)

1. Kritz-Silverstein D, Barrett-Connor E, Corbeau C. Cross-sectional and prospective study of exercise and depressed mood in the elderly: the Rancho Bernardo Study. Am J Epidemiol. 2001;153(6):596-603.
2. Steptoe A, Wardle J, Fuller R, Holte A, Justo J, Sanderman R, Wichstrom L. Leisure-time physical exercise: prevalence, attitudinal correlates, and behavioral correlates among young Europeans from 21 countries. Prev Med. 1997;26(6):845-854.
3. Strawbridge WJ, Deleger S, Roberts RE, Kaplan GA. Physical activity reduces the risk of subsequent depression for older adults. Am J Epidemiol. 2002;156(4):328-334.
4. Farmer ME, Locke BZ, Moscicki EK, Dannenberg AL, Larson DB, Radloff LS. Physical activity and depressive symptoms: the NHANES I Epidemiologic Follow-up Study. Am J Epidemiol. 1988;128(6):1340-1351.
5. Camacho TC, Roberts RE, Lazarus NB, Kaplan GA, Cohen RD. Physical activity and depression: evidence from the Alameda County Study. Am J Epidemiol. 1991;134(2):220-231.
6. Norris R, Carrol D, Cochrane R. The effects of physical activity and exercise training on psychological stress and well-being in an adolescent population. J Psychosom Res. 1992;36(1):55-65.
7. Stephens T. Physical activity and mental health in the United States and Canada: evidence from 4 population surveys. Prev Med. 1988;17(1):35-47.
8. De Moor MHM, Beem AL, Stubbe JH, Boomsma DI, De Geus EJC. Regular exercise, anxiety, depression and personality: a population-based study. Prev Med. 2006;42(4):273-279.
9. Mobily KE, Rubenstein LM, Lemke JH, Ohara MW, Wallace RB. Walking and depression in a cohort of older adults: the Iowa 65+ Rural Health Study. J Aging Phys Act. 1996;4:119-135.
10. van Gool CH, Kempen GIJM, Penninx BWJH, Deeg DJH, Beekman ATF, van Eijk JTM. Relationship between changes in depressive symptoms and unhealthy lifestyles in late middle aged and older persons: results from the Longitudinal Aging Study Amsterdam. Age Ageing. 2003;32(1):81-87.
11. Rhodes RE, Smith NEI. Personality correlates of physical activity: a review and meta-analysis. Br J Sports Med. 2006;40(12):958-965.
12. Cooper-Patrick L, Ford DE, Mead LA, Chang PP, Klag MJ. Exercise and depression in midlife: a prospective study. Am J Public Health. 1997;87(4):670-673.
13. Brown WJ, Ford JH, Burton NW, Marshall AL, Dobson AJ. Prospective study of physical activity and depressive symptoms in middle-aged women. Am J Prev Med. 2005;29(4):265-272.
14. Wise LA, Adams-Campbell LL, Palmer JR, Rosenberg L. Leisure time physical activity in relation to depressive symptoms in the Black Women's Health Study. Ann Behav Med. 2006;32(1):68-76.
15. Weyerer S. Physical inactivity and depression in the community: evidence from the Upper Bavarian Field Study. Int J Sports Med. 1992;13(6):492-496.
16. Steptoe A. Depression and physical activity. In: Steptoe A, ed. Depression and Physical Illness. New York, NY: Cambridge University Press; 2006:348-368.
17. Salmon P. Effects of physical exercise on anxiety, depression, and sensitivity to stress: a unifying theory. Clin Psychol Rev. 2000;21:33-61.
18. Gauvin L, Spence JC. Physical activity and psychological well-being: knowledge base, current issues, and caveats. Nutr Rev. 1996;54(4, pt 2):S53-S65.
19. Scully D, Kremer J, Meade MM, Graham R, Dudgeon K. Physical exercise and psychological well being: a critical review. Br J Sports Med. 1998;32(2):111-120.
20. Folkins CH, Sime WE. Physical fitness training and mental health. Am Psychol. 1981;36(4):373-389.
21. Byrne A, Byrne DG. The effect of exercise on depression, anxiety and other mood states: a review. J Psychosom Res. 1993;37(6):565-574.
22. Brosse AL, Sheets ES, Lett HS, Blumenthal JA. Exercise and the treatment of clinical depression in adults: recent findings and future directions. Sports Med. 2002;32(12):741-760.
23. Craft LL, Landers DM. The effect of exercise on clinical depression and depression resulting from mental illness: a meta-analysis. J Sport Exerc Psychol. 1998;20:339-357.
24. North TC, McCullagh P, Tran ZV. Effect of exercise on depression. Exerc Sport Sci Rev. 1990;18:379-415.
25. Lawlor DA, Hopker SW. The effectiveness of exercise as an intervention in the management of depression: systematic review and meta-regression analysis of randomised controlled trials. BMJ. 2001;322(7289):763-767.
26. Long BC, Vanstavel R. Effects of exercise training on anxiety: a meta-analysis. J Appl Sport Psychol. 1995;7(7):167-189.
27. Blumenthal JA, Babyak MA, Doraiswamy PM, Watkins L, Hoffman BM, Barbour KA, Herman S, Craighead WE, Brosse AL, Waugh R, Hinderliter A, Sherwood A. Exercise and pharmacotherapy in the treatment of major depressive disorder. Psychosom Med. 2007;69(7):587-596.
28. Boomsma DI, Beem AL, van den Berg M, Dolan CV, Koopmans JR, Vink JM, De Geus EJ, Slagboom PE. Netherlands Twin Family Study of Anxious Depression (NETSAD). Twin Res. 2000;3(4):323-334.
29. De Moor MHM, Posthuma D, Hottenga JJ, Willemsen AHM, Boomsma DI, De Geus EJC. Genome-wide linkage scan for exercise participation in Dutch sibling pairs. Eur J Hum Genet. 2007;15(12):1252-1259.
30. Stubbe JH, Boomsma DI, Vink JM, Cornes BK, Martin NG, Skytthe A, Kyvik KO, Rose RJ, Kujala UM, Kaprio J, Harris JR, Pedersen NL, Hunkin J, Spector TD, De Geus EJC. Genetic influences on exercise participation in 37,051 twin pairs from seven countries. PLoS ONE. 2006;1:e22. doi:10.1371/journal.pone.0000022.
31. Neale MC, Cardon LR. Methodology for Genetic Studies of Twins and Families. Dordrecht, the Netherlands: Kluwer Academic Publishers; 1992.
32. Boomsma DI, De Geus EJC, Vink JM, Stubbe JH, Distel MA, Hottenga JJ, Posthuma D, Beijsterveldt TCEM, Hudziak JJ, Bartels M, Willemsen G. Netherlands Twin Register: from twins to twin families. Twin Res Hum Genet. 2006;9(6):849-857.
33. Boomsma DI, Vink JM, van Beijsterveldt TC, De Geus EJ, Beem AL, Mulder EJ, Derks EM, Riese H, Willemsen GA, Bartels M, van den Berg M, Kupper NH, Polderman TJ, Posthuma D, Rietveld MJ, Stubbe JH, Knol LI, Stroet T, van Baal GC. Netherlands Twin Register: a focus on longitudinal research. Twin Res. 2002;5(5):401-406.
34. Achenbach TM. The Young Adult Self Report. Burlington: Dept of Psychiatry, University of Vermont; 1990.
35. Vink JM, Willemsen G, Stubbe JH, Middeldorp CM, Ligthart RSL, Baas KD, Dirkzwager HJC, De Geus EJC, Boomsma DI. Estimating non-response bias in family studies: application to mental health and lifestyle. Eur J Epidemiol. 2004;19(7):623-630.
36. Willemsen G, Posthuma D, Boomsma DI. Environmental factors determine where the Dutch live: results from the Netherlands Twin Register. Twin Res Hum Genet. 2005;8(4):312-317.
37. Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ, O'Brien WL, Bassett DR Jr, Schmitz KH, Emplaincourt PO, Jacobs DR Jr, Leon AS. Compendium of Physical Activities: an update of activity codes and MET intensities. Med Sci Sports Exerc. 2000;32(9)(suppl):S498-S516.
38. Middeldorp CM, Cath DC, van den Berg M, Beem AL, Van Dyck R, Boomsma DI. The association of personality with anxious and depressive psychopathology. In: Canli T, ed. The Biological Basis of Personality and Individual Differences. New York, NY: Guilford Press; 2006:251-272.
39. Spielberger CD, Gorsuch RL, Lushene RE. STAI Manual for the State-Trait Anxiety Inventory. Palo Alto, CA: Consulting Psychologists Press; 1970.
40. Wilde GJS. Neurotische Labiliteit Gemeten Volgens de Vragenlijstmethode [The Questionnaire Method as a Means of Measuring Neurotic Instability]. Amsterdam, the Netherlands: van Rossen; 1970.
41. Eysenck HJ, Eysenck SBG. Eysenck Personality Inventory. San Diego, CA: Educational and Industrial Testing Service; 1964.
42. Muthén LK, Muthén BO. Mplus User's Guide. 4th ed. Los Angeles, CA: Muthén & Muthén; 2007.
43. Muthén B, Satorra A. Complex sample data in structural equation modeling. In: Mardsen PV, ed. Sociological Methodology. Cambridge, MA: Blackwell Publishers; 1995:267-316.
44. Rebollo I, De Moor MHM, Dolan CV, Boomsma DI. Phenotypic factor analysis of family data: correction of the bias due to dependency. Twin Res Hum Genet. 2006;9(3):367-376.
45. Neale MC, Boker SM, Xie G, Maes HH. Mx: Statistical Modeling. 7th ed. Richmond: Dept of Psychiatry, Virginia Commonwealth University; 2006.
46. Chaouloff F. Effects of acute physical exercise on central serotonergic systems. Med Sci Sports Exerc. 1997;29(1):58-62.
47. Dishman RK. Brain monoamines, exercise, and behavioral stress: animal models. Med Sci Sports Exerc. 1997;29(1):63-74.
48. Dishman RK, Berthoud HR, Booth FW, Cotman CW, Edgerton R, Fleshner MR, Gandevia SC, Gomez-Pinilla F, Greenwood BN, Hillman CH, Kramer AF, Levin BE, Moran TH, Russo-Neustadt AA, Salamone JD, Van Hoomissen JD, Wade CE, York DA, Zigmond MJ. Neurobiology of exercise. Obesity (Silver Spring). 2006;14(3):345-356.
49. Goldfarb AH, Jamurtas AZ. Beta-endorphin response to exercise: an update. Sports Med. 1997;24(1):8-16.
50. Middeldorp CM, Birley AJ, Cath DC, Gillespie NA, Willemsen G, Statham DJ, De Geus EJC, Andrews JG, Van Dyck R, Beem AL, Sullivan PF, Martin NG, Boomsma DI. Familial clustering of major depression and anxiety disorders in Australian and Dutch twins and siblings. Twin Res Hum Genet. 2005;8(6):609-615.
51. Heath AC, Kessler RC, Neale MC, Hewitt JK, Eaves LJ, Kendler KS. Testing hypotheses about direction of causation using cross-sectional family data. Behav Genet. 1993;23(1):29-50.
52. Duffy DL, Martin NG. Inferring the direction of causation in cross-sectional twin data: theoretical and empirical considerations. Genet Epidemiol. 1994;11(6):483-502.
53. Haase A, Steptoe A, Sallis JF, Wardle J. Leisure-time physical activity in university students from 23 countries: associations with health beliefs, risk awareness, and national economic development. Prev Med. 2004;39(1):182-190.
54. Kaplan GA, Strawbridge WJ, Cohen RD, Hungerford LR. Natural history of leisuretime physical activity and its correlates: associations with mortality from all causes and cardiovascular disease over 28 years. Am J Epidemiol. 1996;144(8):793-797.
55. Albright A, Franz M, Hornsby G, Kriska A, Marrero D, Ullrich I, Verity LS. Exercise and type 2 diabetes. Med Sci Sports Exerc. 2000;32(7):1345-1360.