FLASH and NPAT positive but not Coilin positive Cajal Bodies correlate with cell ploidy

Cell Cycle

Volumn 7, Issue 15, 2008, Pages 2357-2367

  Bongiorno Borbone, Lucilla ^a   De Cola, Antonella ^a   Vernole, Patrizia ^a   Finos, Livio ^a   Barcaroli, Daniela ^a   Knight, Richard A ^b   Melino, Gerry ^a,b   De Laurenzi, Vincenzo ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Cajal bodies; Coilin; FLASH; NPAT; Ploidy

Indexed keywords

BIOCHEMICAL MARKER;

ANTIBODY LABELING; ARTICLE; CANCER CELL CULTURE; CELL CYCLE PHASE; CELL CYCLE S PHASE; CELL ORGANELLE; CELLULAR DISTRIBUTION; CHROMOSOME NUMBER; COILED BODY; CORRELATION ANALYSIS; DIPLOIDY; HISTONE GENE LOCUS BODY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MAMMAL CELL; MOLECULAR INTERACTION; PLOIDY; REGULATORY MECHANISM; TRANSCRIPTION REGULATION;

EUKARYOTA; MAMMALIA;

EID: 48849098460     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.6344     Document Type: Article

References (25)

1. Barcaroli D, Bongiorno-Borbone L, et al. FLASH is required for histone transcription and S-phase progression. Proc Natl Acad Sci USA 2006; 103:14808-12.
2. Barcaroli D, Dinsdale D, et al. FLASH is an essential component of Cajal bodies. Proc Natl Acad Sci USA 2006; 103:14802-7.
3. Carvalho T, Almeida F, et al. The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body. J Cell Biol 1999; 147:715-28.
4. Chi YH and Jeang KT. Aneuploidy and cancer. J Cell Biochem 2007; 102:531-8.
5. Cristofari G, Adolf E, et al. Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation. Mol Cell 2007; 27:882-9.
6. Gall JG. Cajal bodies: the first 100 years. Annu Rev Cell Dev Biol 2000; 16:273-300.
7. Gall JG, Bellini M, et al. Assembly of the nuclear transcription and processing machinery: Cajal bodies (coiled bodies) and transcriptosomes. Mol Biol Cell 1999; 10:4385-402.
8. Ghule PN, Becker KA, et al. Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells. J Cell Physiol 2007; 213:9-17.
9. Jady BE, Bertrand E, et al. Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal. J Cell Biol 2004; 164:647-52.
10. Jady BE, Richard P, et al. Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres. Mol Biol Cell 2006; 17:944-54.
11. Liu JL, Murphy C, et al. The Drosophila melanogaster Cajal body. J Cell Biol 2006; 172:875-84.
12. Ma T, Van Tine BA, et al. Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/ Cdk2 in Cajal bodies promotes histone gene transcription. Genes Dev 2000; 14:2298-313.
13. Matera AG. Drosophila Cajal bodies: accessories not included. J Cell Biol 2006; 172:791-3.
14. Morency E, Sabra M, et al. A novel cell response triggered by interphase centromere structural instability. J Cell Biol 2007; 177:757-68.
15. 2 by sumoylation of p73. Mol Cell Biol 2004; 24:10593-610.
16. Nicoletti I, Migliorati G, et al. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991; 139:271-9.
17. Rajagopalan H and Lengauer C. Aneuploidy and cancer. Nature 2004; 432:338-41.
18. Sleeman JE, Ajuh P, et al. snRNP protein expression enhances the formation of Cajal bodies containing p80-coilin and SMN. J Cell Sci 2001; 114:4407-19.
19. Tomlinson RL, Ziegler TD, et al. Cell cycle-regulated trafficking of human telomerase to telomeres. Mol Biol Cell 2006; 17:955-65.
20. Tucker KE, Berciano MT, et al. Residual Cajal bodies in coilin knockout mice fail to recruit Sm snRNPs and SMN, the spinal muscular atrophy gene product. J Cell Biol 2001; 154:293-307.
21. Wang A, Ikura T, et al. Dynamic interaction of p220(NPAT) and CBP/p300 promotes S-phase entry. Biochem Biophys Res Commun 2004; 325:1509-16.
22. Wei Y, Jin J, et al. The cyclin E/Cdk2 substrate and Cajal body component p220(NPAT) activates histone transcription through a novel LisH-like domain. Mol Cell Biol 2003; 23:3669-80.
23. Ye X, Wei Y, et al. The cyclin E/Cdk2 substrate p220(NPAT) is required for S-phase entry, histone gene expression, and Cajal body maintenance in human somatic cells. Mol Cell Biol 2003; 23:8586-600.
24. Zhao J, Kennedy BK, et al. NPAT links cyclin E-Cdk2 to the regulation of replicationdependent histone gene transcription. Genes Dev 2000; 14:2283-97.
25. Zhu Y, Tomlinson RL, et al. Telomerase RNA accumulates in Cajal bodies in human cancer cells. Mol Biol Cell 2004; 15:81-90.