메뉴 건너뛰기




Volumn 8, Issue 7, 2008, Pages 1103-1110

Predicting tumor outcomes in urothelial bladder carcinoma: Turning pathways into clinical biomarkers of prognosis

Author keywords

Angiogenesis; Biomarkers; Bladder cancer; Carcinogenesis; Cell cycle regulators; Loss of heterozygosity; Molecular markers; Prognosis; Urothelial carcinoma

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENTARY DNA; FIBROBLAST GROWTH FACTOR RECEPTOR 3; GROWTH FACTOR; MESSENGER RNA; MOLECULAR MARKER; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN; TUMOR MARKER;

EID: 48849092710     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/14737140.8.7.1103     Document Type: Review
Times cited : (15)

References (92)
  • 4
    • 0026636646 scopus 로고
    • Natural history of superficial bladder cancer. Prognostic features and long-term disease course
    • Heney NM. Natural history of superficial bladder cancer. Prognostic features and long-term disease course. Urol. Clin. North Am. 19(3), 429-433 (1992).
    • (1992) Urol. Clin. North Am , vol.19 , Issue.3 , pp. 429-433
    • Heney, N.M.1
  • 5
    • 0029042453 scopus 로고    scopus 로고
    • Holmang S, Hedelin H, Anderstrom C, Johansson SL. The relationship among multiple recurrences, progression and prognosis of patients with stages Ta and T1 transitional cell cancer of the bladder followed for at least 20 years. J. Urol. 153(6), 1823-1826; Discussion 1826-1827 (1995).
    • Holmang S, Hedelin H, Anderstrom C, Johansson SL. The relationship among multiple recurrences, progression and prognosis of patients with stages Ta and T1 transitional cell cancer of the bladder followed for at least 20 years. J. Urol. 153(6), 1823-1826; Discussion 1826-1827 (1995).
  • 6
    • 1242306596 scopus 로고    scopus 로고
    • Survival rates after radical cystectomy according to tumor stage of bladder carcinoma at first presentation
    • May M, Helke C, Nitzke T, Vogler H, Hoschke B. Survival rates after radical cystectomy according to tumor stage of bladder carcinoma at first presentation. Urol. Int. 72(2), 103-111 (2004).
    • (2004) Urol. Int , vol.72 , Issue.2 , pp. 103-111
    • May, M.1    Helke, C.2    Nitzke, T.3    Vogler, H.4    Hoschke, B.5
  • 7
    • 0027240177 scopus 로고
    • Genetic alterations in bladder cancer
    • Dalbagni G, Presti J, Reuter V et al. Genetic alterations in bladder cancer. Lancet 342(8869), 469-471 (1993).
    • (1993) Lancet , vol.342 , Issue.8869 , pp. 469-471
    • Dalbagni, G.1    Presti, J.2    Reuter, V.3
  • 8
    • 0028036255 scopus 로고
    • Two molecular pathways to transitional cell carcinoma of the bladder
    • Spruck CH, Ohneseit PF, Gonzalez-Zulueta M et al. Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res. 54(3), 784-788 (1994).
    • (1994) Cancer Res , vol.54 , Issue.3 , pp. 784-788
    • Spruck, C.H.1    Ohneseit, P.F.2    Gonzalez-Zulueta, M.3
  • 9
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 100(1), 57-70 (2000).
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 10
    • 0032828684 scopus 로고    scopus 로고
    • Bladder cancer clinical guidelines panel summary report on the management of nonmuscle invasive bladder cancer (stages Ta, T1 and TIS). The American Urological Association
    • Smith JA Jr, Labasky RF, Cockett AT, Fracchia JA, Montie JE, Rowland RG. Bladder cancer clinical guidelines panel summary report on the management of nonmuscle invasive bladder cancer (stages Ta, T1 and TIS). The American Urological Association. J. Urol. 162(5), 1697-1701 (1999).
    • (1999) J. Urol , vol.162 , Issue.5 , pp. 1697-1701
    • Smith Jr, J.A.1    Labasky, R.F.2    Cockett, A.T.3    Fracchia, J.A.4    Montie, J.E.5    Rowland, R.G.6
  • 11
    • 33846581566 scopus 로고    scopus 로고
    • Chemotherapy for bladder cancer: Treatment guidelines for neoadjuvant chemotherapy, bladder preservation, adjuvant chemotherapy, and metastatic cancer
    • Sternberg CN, Donat SM, Bellmunt J et al. Chemotherapy for bladder cancer: treatment guidelines for neoadjuvant chemotherapy, bladder preservation, adjuvant chemotherapy, and metastatic cancer. Urology. 69(1 Suppl.), 62-79 (2007).
    • (2007) Urology , vol.69 , Issue.1 SUPPL. , pp. 62-79
    • Sternberg, C.N.1    Donat, S.M.2    Bellmunt, J.3
  • 12
    • 30044432091 scopus 로고    scopus 로고
    • Management of stage T1 tumors of the bladder: International Consensus Panel
    • Nieder AM, Brausi M, Lamm D et al. Management of stage T1 tumors of the bladder: International Consensus Panel. Urology. 66(6 Suppl. 1), 108-125 (2005).
    • (2005) Urology , vol.66 , Issue.6 SUPPL. 1 , pp. 108-125
    • Nieder, A.M.1    Brausi, M.2    Lamm, D.3
  • 13
    • 0020622112 scopus 로고
    • Prognostic factors in local surgical treatment of invasive bladder cancer, with special reference to the presence of urothelial dysplasia
    • Wolf H, Hojgaard K. Prognostic factors in local surgical treatment of invasive bladder cancer, with special reference to the presence of urothelial dysplasia. Cancer 51(9), 1710-1715 (1983).
    • (1983) Cancer , vol.51 , Issue.9 , pp. 1710-1715
    • Wolf, H.1    Hojgaard, K.2
  • 14
    • 32944465832 scopus 로고    scopus 로고
    • Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: A combined analysis of 2596 patients from seven EORTC trials
    • Discussion 475-477
    • Sylvester RJ, van der Meijden AP, Oosterlinck W et al. Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials. Eur. Urol. 49 (3), 466-465; Discussion 475-477 (2006).
    • (2006) Eur. Urol , vol.49 , Issue.3 , pp. 466-465
    • Sylvester, R.J.1    van der Meijden, A.P.2    Oosterlinck, W.3
  • 15
    • 20244362785 scopus 로고    scopus 로고
    • Nomograms including nuclear matrix protein 22 for prediction of disease recurrence and progression in patients with Ta, T1 or CIS transitional cell carcinoma of the bladder
    • Shariat SF, Zippe C, Ludecke G et al. Nomograms including nuclear matrix protein 22 for prediction of disease recurrence and progression in patients with Ta, T1 or CIS transitional cell carcinoma of the bladder. J Urol. 173(5), 1518-1525 (2005).
    • (2005) J Urol , vol.173 , Issue.5 , pp. 1518-1525
    • Shariat, S.F.1    Zippe, C.2    Ludecke, G.3
  • 16
    • 33748470523 scopus 로고    scopus 로고
    • Postoperative nomogram predicting risk of recurrence after radical cystectomy for bladder cancer
    • International Bladder Cancer Nomogram Consortium
    • International Bladder Cancer Nomogram Consortium, Bochner BH, Kattan MW, Vora KC. Postoperative nomogram predicting risk of recurrence after radical cystectomy for bladder cancer. J. Clin. Oncol. 24(24), 3967-3972 (2006).
    • (2006) J. Clin. Oncol , vol.24 , Issue.24 , pp. 3967-3972
    • Bochner, B.H.1    Kattan, M.W.2    Vora, K.C.3
  • 17
    • 0024399684 scopus 로고    scopus 로고
    • Weinberg RA Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis. Cancer Res. 49(14), 3713-3721(1989).
    • Weinberg RA Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis. Cancer Res. 49(14), 3713-3721(1989).
  • 18
    • 0028817977 scopus 로고
    • Factors affecting recurrence and progression in superficial bladder tumours
    • Kurth KH, Denis L, Bouffioux C et al. Factors affecting recurrence and progression in superficial bladder tumours. Eur. J. Cancer. 31A(11), 1840-1846 (1995).
    • (1995) Eur. J. Cancer , vol.31 A , Issue.11 , pp. 1840-1846
    • Kurth, K.H.1    Denis, L.2    Bouffioux, C.3
  • 19
    • 2342591455 scopus 로고    scopus 로고
    • The discovery of receptor tyrosine kinases: Targets for cancer therapy
    • Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat. Rev. Cancer 4(5), 361-370 (2004).
    • (2004) Nat. Rev. Cancer , vol.4 , Issue.5 , pp. 361-370
    • Gschwind, A.1    Fischer, O.M.2    Ullrich, A.3
  • 20
    • 0034969685 scopus 로고    scopus 로고
    • Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors
    • Billerey C, Chopin D, Aubriot-Lorton MH et al. Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors. Am. J. Pathol. 158(6), 1955-1959 (2001).
    • (2001) Am. J. Pathol , vol.158 , Issue.6 , pp. 1955-1959
    • Billerey, C.1    Chopin, D.2    Aubriot-Lorton, M.H.3
  • 21
    • 23444440484 scopus 로고    scopus 로고
    • FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma
    • Jebar AH, Hurst CD, Tomlinson DC, Johnston C, Taylor CF, Knowles MA. FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma. Oncogene 24(33), 5218-5225 (2005).
    • (2005) Oncogene , vol.24 , Issue.33 , pp. 5218-5225
    • Jebar, A.H.1    Hurst, C.D.2    Tomlinson, D.C.3    Johnston, C.4    Taylor, C.F.5    Knowles, M.A.6
  • 22
    • 0141954162 scopus 로고    scopus 로고
    • The role of Ras superfamily proteins in bladder cancer progression
    • Oxford G, Theodorescu D. The role of Ras superfamily proteins in bladder cancer progression. J. Urol. 170(5), 1987-1993 (2003).
    • (2003) J. Urol , vol.170 , Issue.5 , pp. 1987-1993
    • Oxford, G.1    Theodorescu, D.2
  • 23
    • 0035866380 scopus 로고    scopus 로고
    • The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate
    • van Rhijn BW, Lurkin I, Radvanyi F, Kirkels WJ, van der Kwast TH, Zwarthoff EC. The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate. Cancer Res. 61(4), 1265-1268 (2001).
    • (2001) Cancer Res , vol.61 , Issue.4 , pp. 1265-1268
    • van Rhijn, B.W.1    Lurkin, I.2    Radvanyi, F.3    Kirkels, W.J.4    van der Kwast, T.H.5    Zwarthoff, E.C.6
  • 24
    • 0038011950 scopus 로고    scopus 로고
    • Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MIB-1 is superior to pathologic grade for the prediction of clinical outcome
    • van Rhijn BW, Vis AN, van der Kwast TH et al. Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MIB-1 is superior to pathologic grade for the prediction of clinical outcome. J. Clin. Oncol 21(10), 1912-1921 (2003).
    • (2003) J. Clin. Oncol , vol.21 , Issue.10 , pp. 1912-1921
    • van Rhijn, B.W.1    Vis, A.N.2    van der Kwast, T.H.3
  • 25
    • 0035081241 scopus 로고    scopus 로고
    • Fibroblast growth factors
    • Ornitz; DM, Itoh N. Fibroblast growth factors. Genome Biol. 2, 3 (2001).
    • (2001) Genome Biol , vol.2 , pp. 3
    • Ornitz, D.M.1    Itoh, N.2
  • 26
    • 0038011950 scopus 로고    scopus 로고
    • Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MIB-1 is superior to pathologic grade for the prediction of clinical outcome
    • van Rhijn BW, Vis AN, van der Kwast TH et al. Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MIB-1 is superior to pathologic grade for the prediction of clinical outcome. J. Clin. Oncol. 21 (10), 1912-1921 (2003).
    • (2003) J. Clin. Oncol , vol.21 , Issue.10 , pp. 1912-1921
    • van Rhijn, B.W.1    Vis, A.N.2    van der Kwast, T.H.3
  • 27
    • 27744515561 scopus 로고    scopus 로고
    • Role of activating fibroblast growth factor receptor 3 mutations in the development of bladder tumors
    • Zieger K, Dyrskjot L, Wiuf C et al. Role of activating fibroblast growth factor receptor 3 mutations in the development of bladder tumors. Clin. Cancer Res. 11(21), 7709-7719 (2005).
    • (2005) Clin. Cancer Res , vol.11 , Issue.21 , pp. 7709-7719
    • Zieger, K.1    Dyrskjot, L.2    Wiuf, C.3
  • 28
    • 23044479419 scopus 로고    scopus 로고
    • FGFR3 and Tp53 mutations in T1G3 transitional bladder carcinomas: Independent distribution and lack of association with prognosis
    • Hernandez S, Lopez-Knowles E, Lloreta J et al. FGFR3 and Tp53 mutations in T1G3 transitional bladder carcinomas: independent distribution and lack of association with prognosis. Clin. Cancer Res. 11(15), 5444-5450 (2005).
    • (2005) Clin. Cancer Res , vol.11 , Issue.15 , pp. 5444-5450
    • Hernandez, S.1    Lopez-Knowles, E.2    Lloreta, J.3
  • 29
    • 32944481619 scopus 로고    scopus 로고
    • FGFR3 and p53 protein expressions in patients with pTa and pT1 urothelial bladder cancer
    • Mhawech-Fauceglia P, Cheney RT, Fischer G, Beck A, Herrmann FR. FGFR3 and p53 protein expressions in patients with pTa and pT1 urothelial bladder cancer. Eur. J. Surg. Oncol. 32(2), 231-237 (2006).
    • (2006) Eur. J. Surg. Oncol , vol.32 , Issue.2 , pp. 231-237
    • Mhawech-Fauceglia, P.1    Cheney, R.T.2    Fischer, G.3    Beck, A.4    Herrmann, F.R.5
  • 30
    • 33747873545 scopus 로고    scopus 로고
    • PIK3CA mutations are an early genetic alteration associated with FGFR3 mutations in superficial papillary bladder tumors
    • López-Knowles E, Hernández S, Malats N et al. PIK3CA mutations are an early genetic alteration associated with FGFR3 mutations in superficial papillary bladder tumors. Cancer Res. 66(15), 7401-7404 (2006).
    • (2006) Cancer Res , vol.66 , Issue.15 , pp. 7401-7404
    • López-Knowles, E.1    Hernández, S.2    Malats, N.3
  • 31
    • 0035848685 scopus 로고    scopus 로고
    • Role of Ha-ras activation in superficial papillary pathway of urothelial tumor formation
    • Zhang ZT, Pak J, Huang HY et al. Role of Ha-ras activation in superficial papillary pathway of urothelial tumor formation. Oncogene 20(16), 1973-1980 (2001).
    • (2001) Oncogene , vol.20 , Issue.16 , pp. 1973-1980
    • Zhang, Z.T.1    Pak, J.2    Huang, H.Y.3
  • 32
    • 23444440484 scopus 로고    scopus 로고
    • FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma
    • Jebar AH, Hurst CD, Tomlinson DC et al. FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma. Oncogene 24(33), 5218-5225 (2005).
    • (2005) Oncogene , vol.24 , Issue.33 , pp. 5218-5225
    • Jebar, A.H.1    Hurst, C.D.2    Tomlinson, D.C.3
  • 33
    • 0037308988 scopus 로고    scopus 로고
    • Expression of cell-cycle regulatory proteins and their prognostic value in superficial low-grade urothelial cell carcinoma of the bladder
    • Santos LL, Amaro T, Pereira SA et al. Expression of cell-cycle regulatory proteins and their prognostic value in superficial low-grade urothelial cell carcinoma of the bladder. Eur. J. Surg. Oncol. 29(1), 74-80 (2003).
    • (2003) Eur. J. Surg. Oncol , vol.29 , Issue.1 , pp. 74-80
    • Santos, L.L.1    Amaro, T.2    Pereira, S.A.3
  • 34
    • 33746902441 scopus 로고    scopus 로고
    • Molecular and immunohistochemical analysis of the prognostic value of cell-cycle regulators in urothelial neoplasms of the bladder
    • Discussion 515
    • Yurakh AO, Ramos D, Calabuig-Firinas S et al. Molecular and immunohistochemical analysis of the prognostic value of cell-cycle regulators in urothelial neoplasms of the bladder. Eur. Urol. 50(3), 506-515; Discussion 515 (2006).
    • (2006) Eur. Urol , vol.50 , Issue.3 , pp. 506-515
    • Yurakh, A.O.1    Ramos, D.2    Calabuig-Firinas, S.3
  • 35
    • 0033030354 scopus 로고    scopus 로고
    • Frequent genetic alterations in simple urothelial hyperplasias of the bladder in patients with papillary urothelial carcinoma
    • Hartmann A, Moser K, Kriegmair M, Hofstetter A, Hofstaedter F, Knuechel R. Frequent genetic alterations in simple urothelial hyperplasias of the bladder in patients with papillary urothelial carcinoma. Am. J. Pathol. 154(3), 721-727 (1999).
    • (1999) Am. J. Pathol , vol.154 , Issue.3 , pp. 721-727
    • Hartmann, A.1    Moser, K.2    Kriegmair, M.3    Hofstetter, A.4    Hofstaedter, F.5    Knuechel, R.6
  • 36
    • 20844450906 scopus 로고    scopus 로고
    • Deletions of chromosomes 9 and 8p in histologically normal urothelium of patients with bladder cancer
    • Stoehr R, Zietz S, Burger M et al. Deletions of chromosomes 9 and 8p in histologically normal urothelium of patients with bladder cancer. Eur, Urol. 47(1), 58-63 (2005).
    • (2005) Eur, Urol , vol.47 , Issue.1 , pp. 58-63
    • Stoehr, R.1    Zietz, S.2    Burger, M.3
  • 37
    • 0037222796 scopus 로고    scopus 로고
    • Frequent genetic alterations in flat urothelial hyperplasias and concomitant papillary bladder cancer as detected by CGH, LOH, and FISH analyses
    • Obermann EC, Junker K, Stoehr R et al. Frequent genetic alterations in flat urothelial hyperplasias and concomitant papillary bladder cancer as detected by CGH, LOH, and FISH analyses. J. Pathol. 199(1), 50-57 (2003).
    • (2003) J. Pathol , vol.199 , Issue.1 , pp. 50-57
    • Obermann, E.C.1    Junker, K.2    Stoehr, R.3
  • 38
    • 0034693676 scopus 로고    scopus 로고
    • Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer
    • Chow NH, Cairns P, Eisenberger CF et al. Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer. Int. J. Cancer 89(6), 514-518 (2000).
    • (2000) Int. J. Cancer , vol.89 , Issue.6 , pp. 514-518
    • Chow, N.H.1    Cairns, P.2    Eisenberger, C.F.3
  • 39
    • 0036468296 scopus 로고    scopus 로고
    • Occurrence of chromosome 9 and p53 alterations in multifocal dysplasia and carcinoma in situ of human urinary bladder
    • Hartmann A, Schlake G, Zaak D et al. Occurrence of chromosome 9 and p53 alterations in multifocal dysplasia and carcinoma in situ of human urinary bladder. Cancer Res. 62(3), 809-818 (2002).
    • (2002) Cancer Res , vol.62 , Issue.3 , pp. 809-818
    • Hartmann, A.1    Schlake, G.2    Zaak, D.3
  • 40
    • 1542540900 scopus 로고    scopus 로고
    • Numerical aberrations of chromosome 17 and the 9p21 locus are independent predictors of tumor recurrence in non-invasive transitional cell carcinoma of the urinary bladder
    • Kruger S, Mess F, Bohle A, Feller AC. Numerical aberrations of chromosome 17 and the 9p21 locus are independent predictors of tumor recurrence in non-invasive transitional cell carcinoma of the urinary bladder. Int. J. Oncol. 23(1), 41-48 (2003).
    • (2003) Int. J. Oncol , vol.23 , Issue.1 , pp. 41-48
    • Kruger, S.1    Mess, F.2    Bohle, A.3    Feller, A.C.4
  • 41
    • 0028802758 scopus 로고
    • Comparison of bladder cancer outcome in men undergoing hematuria home screening versus those with standard clinical presentations
    • discussion 396-397
    • Messing EM, Young TB, Hunt VB et al. Comparison of bladder cancer outcome in men undergoing hematuria home screening versus those with standard clinical presentations. Urology. 45(3), 387-96; discussion 396-397 (1995).
    • (1995) Urology , vol.45 , Issue.3 , pp. 387-396
    • Messing, E.M.1    Young, T.B.2    Hunt, V.B.3
  • 42
    • 11244344381 scopus 로고    scopus 로고
    • Sengupta S, Harris CC. p53: traffic cop at the crossroads of DNA repair and recombination. Nat. Rev. Mol. Cell Biol. 6(1), 44-55 (2005).
    • Sengupta S, Harris CC. p53: traffic cop at the crossroads of DNA repair and recombination. Nat. Rev. Mol. Cell Biol. 6(1), 44-55 (2005).
  • 43
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone LR, White A, Sprouse J, Livanos E, Jacks T, Tlsty TD. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell. 70(6), 923-935 (1992).
    • (1992) Cell , vol.70 , Issue.6 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 44
    • 0031693740 scopus 로고    scopus 로고
    • Molecular alterations in bladder cancer
    • Cordon-Cardo C. Molecular alterations in bladder cancer. Cancer Surv. 32, 115-131 (1998).
    • (1998) Cancer Surv , vol.32 , pp. 115-131
    • Cordon-Cardo, C.1
  • 45
    • 0031717333 scopus 로고    scopus 로고
    • Molecular alterations in bladder cancer
    • Ortoft TF, Wolf H. Molecular alterations in bladder cancer. Urological Res. 26(4), 223 (1998).
    • (1998) Urological Res , vol.26 , Issue.4 , pp. 223
    • Ortoft, T.F.1    Wolf, H.2
  • 46
    • 0028179153 scopus 로고
    • p53 mutations in human bladder cancer: Genotypic versus phenotypic patterns
    • Cordon-Cardo C, Dalbagni G, Saez GT et al p53 mutations in human bladder cancer: genotypic versus phenotypic patterns. Int. J. Cancer. 56(3), 347-353 (1994).
    • (1994) Int. J. Cancer , vol.56 , Issue.3 , pp. 347-353
    • Cordon-Cardo, C.1    Dalbagni, G.2    Saez, G.T.3
  • 47
    • 0030885701 scopus 로고    scopus 로고
    • p53 expression compared with other prognostic factors in OMS grade-I stage-Ta transitional cell carcinoma of the bladder
    • Casetta G, Gontero P, Russo R, Pacchioni D, Tizzani A. p53 expression compared with other prognostic factors in OMS grade-I stage-Ta transitional cell carcinoma of the bladder. Eur. Urol. 32(2), 229-236 (1997).
    • (1997) Eur. Urol , vol.32 , Issue.2 , pp. 229-236
    • Casetta, G.1    Gontero, P.2    Russo, R.3    Pacchioni, D.4    Tizzani, A.5
  • 48
    • 0028051625 scopus 로고
    • Accumulation of nuclear p53 and tumor progression in bladder cancer
    • Esrig D, Elmajian D, Groshen S et al. Accumulation of nuclear p53 and tumor progression in bladder cancer. N. Engl. J. Med. 331(19), 1259-1264 (1994).
    • (1994) N. Engl. J. Med , vol.331 , Issue.19 , pp. 1259-1264
    • Esrig, D.1    Elmajian, D.2    Groshen, S.3
  • 49
    • 0033839271 scopus 로고    scopus 로고
    • Evaluation of P53 protein overexpression, Ki67 proliferative activity and mitotic index as markers of tumour recurrence in superficial transitional cell carcinoma of the bladder
    • Gontero P, Casetta G, Zitella A et al. Evaluation of P53 protein overexpression, Ki67 proliferative activity and mitotic index as markers of tumour recurrence in superficial transitional cell carcinoma of the bladder. Eur. Urol. 38(3), 287-296 (2000).
    • (2000) Eur. Urol , vol.38 , Issue.3 , pp. 287-296
    • Gontero, P.1    Casetta, G.2    Zitella, A.3
  • 50
    • 0029768723 scopus 로고    scopus 로고
    • Overexpression of p53 protein in a high-risk population of patients with superficial bladder cancer before and after bacillus Calmette-Guerin therapy: Correlation to clinical outcome
    • Lacombe L, Dalbagni G, Zhang ZF et al. Overexpression of p53 protein in a high-risk population of patients with superficial bladder cancer before and after bacillus Calmette-Guerin therapy: correlation to clinical outcome. J. Clin. Oncol. 14(10), 2646-2652 (1996).
    • (1996) J. Clin. Oncol , vol.14 , Issue.10 , pp. 2646-2652
    • Lacombe, L.1    Dalbagni, G.2    Zhang, Z.F.3
  • 51
    • 15644377551 scopus 로고    scopus 로고
    • Biomarker study of primary nonmetastatic versus metastatic invasive bladder cancer. National Cancer Institute Bladder Tumor Marker Network
    • Lianes P, Charytonowicz E, Cordon-Cardo C et al. Biomarker study of primary nonmetastatic versus metastatic invasive bladder cancer. National Cancer Institute Bladder Tumor Marker Network. Clin. Cancer Res. 4(5), 1267-1271 (1998).
    • (1998) Clin. Cancer Res , vol.4 , Issue.5 , pp. 1267-1271
    • Lianes, P.1    Charytonowicz, E.2    Cordon-Cardo, C.3
  • 52
    • 1842737599 scopus 로고    scopus 로고
    • Prognostic factors in stage T1 grade 3 bladder cancer survival: The role of G1-S modulators (p53, p21 Waf1, p27kip1, Cyclin D1, and Cyclin D3) and proliferation index (ki67-MIB1)
    • Lopez-Beltran A, Luque RJ, Alvarez-Kindelan J et al. Prognostic factors in stage T1 grade 3 bladder cancer survival: the role of G1-S modulators (p53, p21 Waf1, p27kip1, Cyclin D1, and Cyclin D3) and proliferation index (ki67-MIB1). Eur. Urol. 45(5), 606-612 (2004).
    • (2004) Eur. Urol , vol.45 , Issue.5 , pp. 606-612
    • Lopez-Beltran, A.1    Luque, R.J.2    Alvarez-Kindelan, J.3
  • 53
    • 4344628144 scopus 로고    scopus 로고
    • Prognostic factors in survival of patients with stage Ta and T1 bladder urothelial tumors: The role of G1-S modulators (p53, p21Waf1, p27Kip1, cyclin D1, and cydin D3), proliferation index, and dinicopathologic parameters
    • Lopez-Beltran A, Luque RJ, Alvarez-Kindelan J et al. Prognostic factors in survival of patients with stage Ta and T1 bladder urothelial tumors: the role of G1-S modulators (p53, p21Waf1, p27Kip1, cyclin D1, and cydin D3), proliferation index, and dinicopathologic parameters. Am. J. Clin. Pathol. 122(3), 444-452 (2004).
    • (2004) Am. J. Clin. Pathol , vol.122 , Issue.3 , pp. 444-452
    • Lopez-Beltran, A.1    Luque, R.J.2    Alvarez-Kindelan, J.3
  • 54
    • 24044554230 scopus 로고    scopus 로고
    • P53 as a prognostic marker for bladder cancer: A meta-analysis and review
    • Malats N, Bustos A, Nascimento CM et al. P53 as a prognostic marker for bladder cancer: a meta-analysis and review. Lancet Oncol. 6(9), 678-686 (2005).
    • (2005) Lancet Oncol , vol.6 , Issue.9 , pp. 678-686
    • Malats, N.1    Bustos, A.2    Nascimento, C.M.3
  • 55
    • 0342484451 scopus 로고    scopus 로고
    • p53 immunohistochemistry in bladder cancer. Combined analysis: A way to go?
    • Schmitz-Drager BJ, Goebell PJ, Heydthausen M. p53 immunohistochemistry in bladder cancer. Combined analysis: a way to go? Urol. Oncol. 5(5), 204-210 (2000).
    • (2000) Urol. Oncol , vol.5 , Issue.5 , pp. 204-210
    • Schmitz-Drager, B.J.1    Goebell, P.J.2    Heydthausen, M.3
  • 56
    • 0032527133 scopus 로고    scopus 로고
    • Effect of p21WAF1/CIP1 expression on tumor progression in bladder cancer
    • Stein JP, Ginsberg DA, Grossfeld GD et al. Effect of p21WAF1/CIP1 expression on tumor progression in bladder cancer. J. Natl Cancer Inst. 90(14), 1072-1079 (1998).
    • (1998) J. Natl Cancer Inst , vol.90 , Issue.14 , pp. 1072-1079
    • Stein, J.P.1    Ginsberg, D.A.2    Grossfeld, G.D.3
  • 57
    • 1842457693 scopus 로고    scopus 로고
    • p53, p21, pRB, and p16 expression predict clinical outcome in cystectomy with bladder cancer
    • Shariat SF, Tokunaga H, Zhou J et al. p53, p21, pRB, and p16 expression predict clinical outcome in cystectomy with bladder cancer. J. Clin. Oncol. 22(6), 1014-1024 (2004).
    • (2004) J. Clin. Oncol , vol.22 , Issue.6 , pp. 1014-1024
    • Shariat, S.F.1    Tokunaga, H.2    Zhou, J.3
  • 58
    • 33846003867 scopus 로고    scopus 로고
    • Predictive value of cell cycle biomarkers in nonmuscle invasive bladder transitional cell carcinoma
    • discussion 487
    • Shariat SF, Ashfaq R, Sagalowsky AI, Lotan Y. Predictive value of cell cycle biomarkers in nonmuscle invasive bladder transitional cell carcinoma. J. Urol. 177(2), 481-487; discussion 487 (2007).
    • (2007) J. Urol , vol.177 , Issue.2 , pp. 481-487
    • Shariat, S.F.1    Ashfaq, R.2    Sagalowsky, A.I.3    Lotan, Y.4
  • 59
    • 0026058874 scopus 로고
    • The retinoblastoma gene product regulates progression through the G1 phase of the Cell cycle
    • Goodrich DW, Wang NP, Qian YW et al. The retinoblastoma gene product regulates progression through the G1 phase of the Cell cycle. Cell 67(2), 293-302 (1991).
    • (1991) Cell , vol.67 , Issue.2 , pp. 293-302
    • Goodrich, D.W.1    Wang, N.P.2    Qian, Y.W.3
  • 60
    • 0025905183 scopus 로고
    • The F2F transcription factor is a cellular target for the RB protein
    • Chellappan SP, Hiebert S, Mudryj M, Horowitz JM, Nevins JR. The F2F transcription factor is a cellular target for the RB protein. Cell 65(6), 1053-1061 (1991).
    • (1991) Cell , vol.65 , Issue.6 , pp. 1053-1061
    • Chellappan, S.P.1    Hiebert, S.2    Mudryj, M.3    Horowitz, J.M.4    Nevins, J.R.5
  • 61
    • 33749053635 scopus 로고    scopus 로고
    • Molecular biology of bladder cancer: Prognostic and clinical implications
    • Mitra AP, Lin H, Datar RH, Cote RJ. Molecular biology of bladder cancer: prognostic and clinical implications. Clin. Genitourin. Cancer 5(1), 67-77 (2006).
    • (2006) Clin. Genitourin. Cancer , vol.5 , Issue.1 , pp. 67-77
    • Mitra, A.P.1    Lin, H.2    Datar, R.H.3    Cote, R.J.4
  • 62
    • 1842509884 scopus 로고    scopus 로고
    • Combined effects of p53, p21, and pRb expression in the progression of bladder transitional cell carcinoma
    • Chatterjee SJ, Datar R, Youssefzadeh D et al. Combined effects of p53, p21, and pRb expression in the progression of bladder transitional cell carcinoma. J. Clin. Oncol. 22(6), 1007-1013 (2004).
    • (2004) J. Clin. Oncol , vol.22 , Issue.6 , pp. 1007-1013
    • Chatterjee, S.J.1    Datar, R.2    Youssefzadeh, D.3
  • 63
    • 0032521376 scopus 로고    scopus 로고
    • Elevated and absent pRb expression is associated with bladder cancer progression and has cooperative effects with p53
    • Cote RJ, Dunn MD, Chatterjee SJ et al. Elevated and absent pRb expression is associated with bladder cancer progression and has cooperative effects with p53. Cancer Res. 58(6), 1090-1094 (1998).
    • (1998) Cancer Res , vol.58 , Issue.6 , pp. 1090-1094
    • Cote, R.J.1    Dunn, M.D.2    Chatterjee, S.J.3
  • 64
    • 0033565558 scopus 로고    scopus 로고
    • Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma
    • Zhang ZT, Pak J, Shapiro E, Sun TT, Wu XR. Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma. Cancer Res. 59(14), 3512-3517 (1999).
    • (1999) Cancer Res , vol.59 , Issue.14 , pp. 3512-3517
    • Zhang, Z.T.1    Pak, J.2    Shapiro, E.3    Sun, T.T.4    Wu, X.R.5
  • 65
    • 0034004182 scopus 로고    scopus 로고
    • Prognostic value of the expression of E-cadherin and α-catenin in bladder cancer
    • Garcia del Muro X Torregrosa A, Munoz J et al. Prognostic value of the expression of E-cadherin and α-catenin in bladder cancer. Eur. J. Cancer. 36(3), 357-362 (2000).
    • (2000) Eur. J. Cancer , vol.36 , Issue.3 , pp. 357-362
    • Garcia del Muro, X.1    Torregrosa, A.2    Munoz, J.3
  • 66
    • 0242440246 scopus 로고    scopus 로고
    • Preoperative plasma soluble E-cadherin predicts metastases to lymph nodes and prognosis in patients undergoing radical cystectomy
    • Matsumoto K, Shariat SF, Casella R, Wheeler TM, Slawin KM, Lerner SP. Preoperative plasma soluble E-cadherin predicts metastases to lymph nodes and prognosis in patients undergoing radical cystectomy. J. Urol. 170(6 Pt 1), 2248-2252 (2003).
    • (2003) J. Urol , vol.170 , Issue.6 PART 1 , pp. 2248-2252
    • Matsumoto, K.1    Shariat, S.F.2    Casella, R.3    Wheeler, T.M.4    Slawin, K.M.5    Lerner, S.P.6
  • 67
    • 0034089127 scopus 로고    scopus 로고
    • Low E-cadherin expression in bladder cancer at the transcriptional and protein level provides prognostic information
    • Popov Z, Gil-Diez de Medina S, Lefrere-Belda MA et al. Low E-cadherin expression in bladder cancer at the transcriptional and protein level provides prognostic information. Br. J. Cancer 83(2), 209-214 (2000).
    • (2000) Br. J. Cancer , vol.83 , Issue.2 , pp. 209-214
    • Popov, Z.1    Gil-Diez de Medina, S.2    Lefrere-Belda, M.A.3
  • 68
    • 0035151885 scopus 로고    scopus 로고
    • E-cadherin expression predicts clinical outcome in carcinoma in situ of the urinary bladder
    • Shariat SF, Pahlavan S, Baseman AG et al. E-cadherin expression predicts clinical outcome in carcinoma in situ of the urinary bladder. Urology 57(1), 60-65 (2001).
    • (2001) Urology , vol.57 , Issue.1 , pp. 60-65
    • Shariat, S.F.1    Pahlavan, S.2    Baseman, A.G.3
  • 69
    • 13744263722 scopus 로고    scopus 로고
    • Apoptosis and chemotherapy for bladder cancer
    • McKnight JJ, Gray SB, O'Kane HF et al. Apoptosis and chemotherapy for bladder cancer. J. Urol. 173, 683-690 (2005).
    • (2005) J. Urol , vol.173 , pp. 683-690
    • McKnight, J.J.1    Gray, S.B.2    O'Kane, H.F.3
  • 70
    • 33646022893 scopus 로고    scopus 로고
    • Soluble Fas-A promising novel urinary marker for the detection of recurrent superficial bladder cancer
    • Svatek RS, Herman MP, Lotan Y et al. Soluble Fas-A promising novel urinary marker for the detection of recurrent superficial bladder cancer. Cancer 106, 1701-1707 (2006).
    • (2006) Cancer , vol.106 , pp. 1701-1707
    • Svatek, R.S.1    Herman, M.P.2    Lotan, Y.3
  • 71
    • 33846469888 scopus 로고    scopus 로고
    • Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy
    • Karam JA, Lotan Y, Karakiewicz PL et al. Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy. Lancet Oncol. 8(128), 128-136 (2007).
    • (2007) Lancet Oncol , vol.8 , Issue.128 , pp. 128-136
    • Karam, J.A.1    Lotan, Y.2    Karakiewicz, P.L.3
  • 72
    • 0032413097 scopus 로고    scopus 로고
    • Bcl-2 and p53 expression in invasive bladder cancers
    • Kong G, Shin KY, Oh YH et al. Bcl-2 and p53 expression in invasive bladder cancers. Acta Oncol. 37, 715-720 (1998).
    • (1998) Acta Oncol , vol.37 , pp. 715-720
    • Kong, G.1    Shin, K.Y.2    Oh, Y.H.3
  • 74
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma
    • Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma. N. Engl. J. Med. 324(1), 1-8 (1991).
    • (1991) N. Engl. J. Med , vol.324 , Issue.1 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 75
    • 0028884557 scopus 로고
    • Angiogenesis in bladder cancer: Relationship between microvessel density and tumor prognosis
    • Bochner BH, Cote RJ, Weidner N et al. Angiogenesis in bladder cancer: relationship between microvessel density and tumor prognosis. J. Natl. Cancer Inst. 87(21), 1603-1612 (1995).
    • (1995) J. Natl. Cancer Inst , vol.87 , Issue.21 , pp. 1603-1612
    • Bochner, B.H.1    Cote, R.J.2    Weidner, N.3
  • 76
    • 0034827699 scopus 로고    scopus 로고
    • Serum levels of vascular endothelial growth factor as a prognostic factor in bladder cancer
    • Bernardini S, Fauconnet S, Chabannes E, Henry PC, Adessi G, Bittard H. Serum levels of vascular endothelial growth factor as a prognostic factor in bladder cancer. J. Urol. 166(4), 1275-1279 (2001).
    • (2001) J. Urol , vol.166 , Issue.4 , pp. 1275-1279
    • Bernardini, S.1    Fauconnet, S.2    Chabannes, E.3    Henry, P.C.4    Adessi, G.5    Bittard, H.6
  • 77
    • 33749578614 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C expression in bladder transitional cell cancer and its relationship to lymph node metastasis
    • Zu X, Tang Z, Li Y, Gao N, Ding J, Qi L. Vascular endothelial growth factor-C expression in bladder transitional cell cancer and its relationship to lymph node metastasis. BJU Int. 98, 1090-1093 (2006).
    • (2006) BJU Int , vol.98 , pp. 1090-1093
    • Zu, X.1    Tang, Z.2    Li, Y.3    Gao, N.4    Ding, J.5    Qi, L.6
  • 78
    • 0029562902 scopus 로고
    • Steps in tumor metastasis: New concepts from intravital videomicroscopy
    • Chambers AF, MacDonald IC, Schmidt EE et al. Steps in tumor metastasis: new concepts from intravital videomicroscopy. Cancer Metastasis Rev. 14(4), 279-301 (1995).
    • (1995) Cancer Metastasis Rev , vol.14 , Issue.4 , pp. 279-301
    • Chambers, A.F.1    MacDonald, I.C.2    Schmidt, E.E.3
  • 79
    • 0037817325 scopus 로고    scopus 로고
    • Significant association of Rho/ ROCK pathway with invasion and metastasis of bladder cancer
    • Kamai T, Tsujii T, Arai K et al. Significant association of Rho/ ROCK pathway with invasion and metastasis of bladder cancer. Clin. Cancer Res. 9(7), 2632-2641 (2003).
    • (2003) Clin. Cancer Res , vol.9 , Issue.7 , pp. 2632-2641
    • Kamai, T.1    Tsujii, T.2    Arai, K.3
  • 80
    • 0037112363 scopus 로고    scopus 로고
    • RhoGDI2 is an invasion and metastasis suppressor gene in human cancer
    • Gildea JJ, Seraj MJ, Oxford G et al. RhoGDI2 is an invasion and metastasis suppressor gene in human cancer. Cancer Res. 62(22), 6418-6423 (2002).
    • (2002) Cancer Res , vol.62 , Issue.22 , pp. 6418-6423
    • Gildea, J.J.1    Seraj, M.J.2    Oxford, G.3
  • 81
    • 2542606977 scopus 로고    scopus 로고
    • Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer
    • Theodorescu D, Sapinoso LM, Conaway MR, Oxford G, Hampton GM, Frierson HF Jr. Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer. Clin. Cancer Res. 10(11), 3800-3806 (2004).
    • (2004) Clin. Cancer Res , vol.10 , Issue.11 , pp. 3800-3806
    • Theodorescu, D.1    Sapinoso, L.M.2    Conaway, M.R.3    Oxford, G.4    Hampton, G.M.5    Frierson Jr, H.F.6
  • 82
    • 30044446209 scopus 로고    scopus 로고
    • Prognostic markers for bladder cancer: International Consensus Panel on bladder tumor markers
    • Habuchi T, Marberger M, Droller MJ et al. Prognostic markers for bladder cancer: International Consensus Panel on bladder tumor markers. Urology 66(6 Suppl. 1), 64-74 (2005).
    • (2005) Urology , vol.66 , Issue.6 SUPPL. 1 , pp. 64-74
    • Habuchi, T.1    Marberger, M.2    Droller, M.J.3
  • 83
    • 33644867290 scopus 로고    scopus 로고
    • Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays
    • Sanchez-Carbayo M, Socci ND, Lozano J, Saint F, Cordon-Cardo C. Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays. J. Clin. Oncol. 24(5), 778-789 (2006).
    • (2006) J. Clin. Oncol , vol.24 , Issue.5 , pp. 778-789
    • Sanchez-Carbayo, M.1    Socci, N.D.2    Lozano, J.3    Saint, F.4    Cordon-Cardo, C.5
  • 84
    • 2542418023 scopus 로고    scopus 로고
    • Identifying superficial, muscle-invasive, and metastasizing transitional cell carcinoma of the bladder: Use of cDNA array analysis of gene expression profiles
    • Modlich O, Prisack HB, Pitschke G et al. Identifying superficial, muscle-invasive, and metastasizing transitional cell carcinoma of the bladder: use of cDNA array analysis of gene expression profiles. Clin. Cancer Res. 10(10), 3410-3421 (2004).
    • (2004) Clin. Cancer Res , vol.10 , Issue.10 , pp. 3410-3421
    • Modlich, O.1    Prisack, H.B.2    Pitschke, G.3
  • 85
    • 27944474390 scopus 로고    scopus 로고
    • Gene expression profiling of noninvasive primary urothelial tumours using microarrays
    • Aaboe M, Marcussen N, Jensen KM, Thykjaer T, Dyrskjot L, Orntoft TF. Gene expression profiling of noninvasive primary urothelial tumours using microarrays. Br. J. Cancer. 93(10), 1182-1190 (2005).
    • (2005) Br. J. Cancer , vol.93 , Issue.10 , pp. 1182-1190
    • Aaboe, M.1    Marcussen, N.2    Jensen, K.M.3    Thykjaer, T.4    Dyrskjot, L.5    Orntoft, T.F.6
  • 86
    • 0037435030 scopus 로고    scopus 로고
    • Mass spectrometry-based proteomics
    • Aebersold R, Mann M. Mass spectrometry-based proteomics. Nature 422(6928), 198-207 (2003).
    • (2003) Nature , vol.422 , Issue.6928 , pp. 198-207
    • Aebersold, R.1    Mann, M.2
  • 87
    • 0035866788 scopus 로고    scopus 로고
    • Identification of gene expression patterns in superficial and invasive human bladder cancer
    • Thykjaer T, Workman C, Orntoft TF et al. Identification of gene expression patterns in superficial and invasive human bladder cancer. Cancer Res. 61, 2492-2499 (2001).
    • (2001) Cancer Res , vol.61 , pp. 2492-2499
    • Thykjaer, T.1    Workman, C.2    Orntoft, T.F.3
  • 88
    • 2942648713 scopus 로고    scopus 로고
    • The p53 pathway: Targets for the development of novel cancer therapeutics
    • Wang S, El-Deiry WS. The p53 pathway: targets for the development of novel cancer therapeutics. Cancer Treat. Res. 119, 175-187 (2004).
    • (2004) Cancer Treat. Res , vol.119 , pp. 175-187
    • Wang, S.1    El-Deiry, W.S.2
  • 89
    • 1842529509 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Cancer gene therapy using tumour suppressor genes
    • McNeish IA, Bell SJ, Lemoine NR. Gene therapy progress and prospects: cancer gene therapy using tumour suppressor genes. Gene Ther. 11(6), 497-503 (2004).
    • (2004) Gene Ther , vol.11 , Issue.6 , pp. 497-503
    • McNeish, I.A.1    Bell, S.J.2    Lemoine, N.R.3
  • 90
    • 33751232026 scopus 로고    scopus 로고
    • Molecular markers of prognosis and novel therapeutic strategies for urothelial cell carcinomas
    • Thomas CY, Theodorescu D. Molecular markers of prognosis and novel therapeutic strategies for urothelial cell carcinomas. World J. Urol. 24(5), 565-578 (2006).
    • (2006) World J. Urol , vol.24 , Issue.5 , pp. 565-578
    • Thomas, C.Y.1    Theodorescu, D.2
  • 91
    • 34247337239 scopus 로고    scopus 로고
    • Molecular pathways in invasive bladder cancer: New insights into mechanisms, progression, and target identification
    • Mitra AP, Datar RH, Cote RJ. Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification. J. Clin. Oncol. 24(35), 5552-5564 (2006).
    • (2006) J. Clin. Oncol , vol.24 , Issue.35 , pp. 5552-5564
    • Mitra, A.P.1    Datar, R.H.2    Cote, R.J.3
  • 92
    • 23844468385 scopus 로고    scopus 로고
    • Endothelin axis is a target of the lung metastasis suppressor gene RhoGDI2
    • Titus B, Frierson HF Jr, Conaway M et al. Endothelin axis is a target of the lung metastasis suppressor gene RhoGDI2. Cancer Res. 65(16), 7320-7327 (2005).
    • (2005) Cancer Res , vol.65 , Issue.16 , pp. 7320-7327
    • Titus, B.1    Frierson Jr, H.F.2    Conaway, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.