Overexpression of p53 protein in a high-risk population of patients with superficial bladder cancer before and after Bacillus Calmette-Guerin therapy: Correlation to clinical outcome

Journal of Clinical Oncology

Volumn 14, Issue 10, 1996, Pages 2646-2652

  Lacombe, L ^a   Dalbagni, G ^a   Zhang, Z F ^a   Cordon Cardo, C ^a   Fair, W R ^a   Herr, H W ^a   Reuter, V E ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; PROTEIN P53;

ARTICLE; BLADDER CANCER; CANCER PREVENTION; CANCER RISK; CANCER SURVIVAL; CORRELATION FUNCTION; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPERFICIAL CANCER;

EID: 0029768723     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1996.14.10.2646     Document Type: Article

References (37)

1. Whitmore WF Jr: Bladder cancer: Defining the clinical problem. Urology 23:5-8, 1984
2. Wingo PA, Tong T, Bolden S: Cancer statistics, 1995. CA Cancer J Clin 45:8-30, 1995
3. Reuter VE, Metamed MR: The lower urinary tract, in Sternberg SS (ed): Diagnostic Surgical Pathology (ed 2). New York, NY, Raven, 1994, pp 1767-1805
4. Althausen AF, Prout GR Jr, Daly JJ: Non-invasive papillary carcinoma of the bladder associated with carcinoma in situ. J Urol 116:575-580, 1976
5. Herr HW: Carcinoma in situ of the bladder. Semin Urol 1:15-22, 1983
6. Malmström P-U, Busch C, Norlén BJ: Recurrence, progression and survival in bladder cancer. Scand J Urol Nephrol 21:185-195, 1987
7. Utz DC, Farrow GM, Rife CC. et al: Carcinoma in situ of the bladder. Cancer 45:1842-1848, 1980
8. Herr HW, Jakse G, Sheinfeld J: The T1 bladder tumor. Semin Urol 8:254-261, 1990
9. Anderström C, Johansson S, Nilsson S: The significance of lamina propria invasion on the prognosis of patients with bladder tumors. J Urol 124:23-26, 1980
10. Rübben H, Lutzeyer W, Fischer N, et al: Natural history and treatment of low and high risk superficial bladder tumors. J Urol 139:283-285, 1988
11. Kavoussi LJ, Torrence RJ, Gillen DP, et al: Results of 6 weekly intravesical Bacillus Calmette-Guérin instillations on the treatment of superficial bladder tumors. J Urol 139:935-940, 1988
12. Herr- HW, Laudone VP, Badalament RA, et al: Bacillus Calmelte-Guérin therapy alters the progression of superficial bladder cancer. J Clin Oncol 6:1450-1455, 1988
13. Herr HW, Wartinger DD, Fair WR, et al: Bacillus CalmetteGuérin therapy for superficial bladder cancer: A 10-year followup. J Urol 147:1020-1023, 1992
14. Herr HW: Progression of stage T1 bladder tumors after intravesical Bacillus Calmette-Guérin. J Urol 145:40-44, 1991
15. Martinez J, Georgoff I, Levine AJ: Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes Dev 5:151-159, 1991
16. Hupp TR, Meek DW, Midgley CA, et al: Regulation of the specific DNA binding function of p53. Cell 71:875-886, 1992
17. Yin Y, Tainsky MA, Bischoff FZ, et al: Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant P53 alleles. Cell 70:937-948, 1992
18. Cossman J, Schlegel R: p53 in the diagnosis of human neoplasia. J Natl Cancer Inst 83:980-981, 1991
19. Lane DP, Benchimol S: p53: Oncogene or anti-oncogene? Genes Dev 4:1-8, 1990
20. Finlay CA, Hinds PW, Tan TH, et al: Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol Cell Biol 8:531-539, 1988
21. Cordon-Cardo C, Dalbagni G, Saez GT, et al: p53 mutations in human bladder cancer: Genotypic versus phenotypic patterns. Int J Cancer 56:347-353, 1994
22. Hollstein M, Sidransky D, Vogelstein B, et al: p53 mutations in human cancers. Science 253:49-53, 1991
23. Sidransky D, Von Eschenbach A, Tsai YC, et al: Identification of p53 gene mutations in bladder cancers and urine samples. Science 252:706-709, 1991
24. Dalbagni G, Presti JC Jr, Reuter VE, et al: Molecular genetic alterations of chromosome 17 and p53 nuclear overexpression in human bladder cancer. Diagn Mol Pathol 2:4-13, 1993
25. Sarkis AS, Dalbagni G, Cordon-Cardo C, et al: Association of p53 nuclear overexpression and tumor progression in carcinoma in situ of the bladder. J Urol 152:388-392, 1994
26. Sarkis AS, Zhang Z, Cordon-Cardo C, et al: p53 nuclear overexpression and disease progression in Ta bladder carcinoma. Int J Oncol 3:355-360, 1993
27. Sarkis AS, Dalbagni G, Melamed J, et al: Prognostic significance of p53 nuclear overexpression in superficially invasive (T1) bladder carcinoma (TCC). J Urol 150:1993 (abstr)
28. Esrig D, Elmajian D, Groshen S, et al: Accumulation of nuclear p53 and tumor progression in bladder cancer. N Engl J Med 331:1259-1264, 1994
29. Lipponen PK: Over-expression of p53 nuclear oncoprotein in transitional-cell bladder cancer and its prognostic value. Int J Cancer 53:365-370, 1993
30. Sarkis AS, Dalbagni G, Cordon-Cardo C, et al: Nuclear overexpression of p53 protein in transitional cell bladder carcinoma: A marker of disease progression. J Natl Cancer Inst 85:53-59, 1993
31. Kuczyk MA, Bokemeyer C, Hervatin C, et al: p53 immunohistochemistry as an independent prognostic factor for superficial transitional cell carcinoma of the bladder. Br J Cancer 71:201-205, 1995
32. Cordon-Cardo C, Finstad CL, Bander NH, et al: Immunoanatomic distribution of cytostructural and tissue-associated antigens in the human urinary tract. Am J Pathol 126:269-284, 1987
33. Banks L, Matlashewski G, Crawford L: Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression. Eur J Biochem 159:529-534, 1986
34. Mehta CR, Patel NR: A network algorithm for performing Fisher's test in r × c contingency tables. J Am Stat Assoc 78:427-434, 1983
35. Peto R, Pike MC, Armitage P, et al: Design and analysis of randomized trials requiring prolonged observation of each patient. II. Analysis and examples. Br J Cancer 35:1-39, 1977
36. Cox DR: Partial likelihood. Biometrika 62:269-279, 1975
37. Kerns BJ, Jordan PA, Moore MB, et al: p53 overexpression in formalin-fixed, paraffin-embedded tissue detected by immunohistochemistry. J Histochem Cytochem 40:1047-1051, 1991