메뉴 건너뛰기




Volumn , Issue , 2008, Pages

PPAR alpha regulation of the immune response and autoimmune encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 17; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RETINOID X RECEPTOR; TRANSCRIPTION FACTOR;

EID: 48749132127     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2008/546753     Document Type: Review
Times cited : (44)

References (38)
  • 1
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergne B., Wahli W., Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocrine Reviews 1999 20 5 649 688
    • (1999) Endocrine Reviews , vol.20 , Issue.5 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 2
    • 0012473279 scopus 로고
    • The nuclear receptor super-family: The second decade
    • Mangelsdorf D. J., Thummel C., Beato M., The nuclear receptor super-family: the second decade Cell 1995 83 6 835 839
    • (1995) Cell , vol.83 , Issue.6 , pp. 835-839
    • Mangelsdorf, D.J.1    Thummel, C.2    Beato, M.3
  • 3
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, - β, and - γ in the adult rat
    • Braissant O., Foufelle F., Scotto C., Dauça M., Wahli W., Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-α,-β, and-γ in the adult rat Endocrinology 1996 137 1 354 366
    • (1996) Endocrinology , vol.137 , Issue.1 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauça, M.4    Wahli, W.5
  • 7
    • 0027418515 scopus 로고
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis-I: Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
    • The IFNB Multiple Sclerosis Study Group
    • The IFNB Multiple Sclerosis Study Group, Interferon beta-1b is effective in relapsing-remitting multiple sclerosis-I: clinical results of a multicenter, randomized, double-blind, placebo-controlled trial Neurology 1993 43 4 655 661
    • (1993) Neurology , vol.43 , Issue.4 , pp. 655-661
  • 8
    • 0008678962 scopus 로고    scopus 로고
    • Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis
    • Jacobs L. D., Cookfair D. L., Rudick R. A., Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis Annals of Neurology 1996 39 3 285 294
    • (1996) Annals of Neurology , vol.39 , Issue.3 , pp. 285-294
    • Jacobs, L.D.1    Cookfair, D.L.2    Rudick, R.A.3
  • 9
    • 0029082566 scopus 로고
    • Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: Results of a phase III multicenter, double-blind, placebo-controlled trial
    • Johnson K. P., Brooks B. R., Cohen J. A., Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind, placebo-controlled trial Neurology 1995 45 7 1268 1276
    • (1995) Neurology , vol.45 , Issue.7 , pp. 1268-1276
    • Johnson, K.P.1    Brooks, B.R.2    Cohen, J.A.3
  • 10
    • 8044242916 scopus 로고    scopus 로고
    • Randomized placebo-controlled trial of mitoxantrone in relapsing-remitting multiple sclerosis: 24-month clinical and MRI outcome
    • Millefiorini E., Gasperini C., Pozzilli C., Randomized placebo-controlled trial of mitoxantrone in relapsing-remitting multiple sclerosis: 24-month clinical and MRI outcome Journal of Neurology 1997 244 3 153 159
    • (1997) Journal of Neurology , vol.244 , Issue.3 , pp. 153-159
    • Millefiorini, E.1    Gasperini, C.2    Pozzilli, C.3
  • 11
    • 22844439662 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis
    • Kleinschmidt-DeMasters B. K., Tyler K. L., Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis The New England Journal of Medicine 2005 353 4 369 374
    • (2005) The New England Journal of Medicine , vol.353 , Issue.4 , pp. 369-374
    • Kleinschmidt-Demasters, B.K.1    Tyler, K.L.2
  • 13
    • 22844445587 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease
    • Van Assche G., Van Ranst M., Sciot R., Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease The New England Journal of Medicine 2005 353 4 362 368
    • (2005) The New England Journal of Medicine , vol.353 , Issue.4 , pp. 362-368
    • Van Assche, G.1    Van Ranst, M.2    Sciot, R.3
  • 14
    • 0028067008 scopus 로고
    • The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases
    • Miller S. D., Karpus W. J., The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases Immunology Today 1994 15 8 356 361
    • (1994) Immunology Today , vol.15 , Issue.8 , pp. 356-361
    • Miller, S.D.1    Karpus, W.J.2
  • 15
    • 0032475922 scopus 로고    scopus 로고
    • Activation of proliferator-activated receptorsα and γ induces apoptosis of human monocyte-derived macrophages
    • Chinetti G., Griglio S., Antonucci M., Activation of proliferator- activated receptorsα and γ induces apoptosis of human monocyte-derived macrophages The Journal of Biological Chemistry 1998 273 40 25573 25580
    • (1998) The Journal of Biological Chemistry , vol.273 , Issue.40 , pp. 25573-25580
    • Chinetti, G.1    Griglio, S.2    Antonucci, M.3
  • 16
    • 0036510359 scopus 로고    scopus 로고
    • Nuclear receptor peroxisome proliferator-activated receptorα (PPARα) is expressed in resting murine lymphocytes. the PPARα in T and B lymphocytes is both transactivation and transrepression competent
    • Jones D. C., Ding X., Daynes R. A., Nuclear receptor peroxisome proliferator-activated receptorα (PPARα) is expressed in resting murine lymphocytes. The PPARα in T and B lymphocytes is both transactivation and transrepression competent The Journal of Biological Chemistry 2002 277 9 6838 6845
    • (2002) The Journal of Biological Chemistry , vol.277 , Issue.9 , pp. 6838-6845
    • Jones, D.C.1    Ding, X.2    Daynes, R.A.3
  • 17
    • 0037087324 scopus 로고    scopus 로고
    • Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors
    • Cunard R., Ricote M., DiCampli D., Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors Journal of Immunology 2002 168 6 2795 2802
    • (2002) Journal of Immunology , vol.168 , Issue.6 , pp. 2795-2802
    • Cunard, R.1    Ricote, M.2    Dicampli, D.3
  • 18
    • 33947674880 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-α activation inhibits Langerhans cell function
    • Dubrac S., Stoitzner P., Pirkebner D., Peroxisome proliferator-activated receptor-α activation inhibits Langerhans cell function Journal of Immunology 2007 178 7 4362 4372
    • (2007) Journal of Immunology , vol.178 , Issue.7 , pp. 4362-4372
    • Dubrac, S.1    Stoitzner, P.2    Pirkebner, D.3
  • 20
    • 0033527569 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptorα negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF- κ B and AP-1
    • Delerive P., De Bosscher K., Besnard S., Peroxisome proliferator- activated receptorα negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF- κ B and AP-1 The Journal of Biological Chemistry 1999 274 45 32048 32054
    • (1999) The Journal of Biological Chemistry , vol.274 , Issue.45 , pp. 32048-32054
    • Delerive, P.1    De Bosscher, K.2    Besnard, S.3
  • 21
    • 0037114190 scopus 로고    scopus 로고
    • WY14,643, a PPARα ligand, has profound effects on immune responses in vivo
    • Cunard R., DiCampli D., Archer D. C., WY14,643, a PPARα ligand, has profound effects on immune responses in vivo Journal of Immunology 2002 169 12 6806 6812
    • (2002) Journal of Immunology , vol.169 , Issue.12 , pp. 6806-6812
    • Cunard, R.1    Dicampli, D.2    Archer, D.C.3
  • 22
    • 34447101284 scopus 로고    scopus 로고
    • Fenofibrate represses interleukin-17 and interferon- γ expression and improves colitis in interleukin-10-deficient mice
    • Lee J. W., Bajwa P. J., Carson M. J., Fenofibrate represses interleukin-17 and interferon- γ expression and improves colitis in interleukin-10-deficient mice Gastroenterology 2007 133 1 108 123
    • (2007) Gastroenterology , vol.133 , Issue.1 , pp. 108-123
    • Lee, J.W.1    Bajwa, P.J.2    Carson, M.J.3
  • 23
    • 0038544686 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptorα negatively regulates T-bet transcription through suppression of p38 mitogen-activated protein kinase activation
    • Jones D. C., Ding X., Zhang T. Y., Daynes R. A., Peroxisome proliferator-activated receptorα negatively regulates T-bet transcription through suppression of p38 mitogen-activated protein kinase activation Journal of Immunology 2003 171 1 196 203
    • (2003) Journal of Immunology , vol.171 , Issue.1 , pp. 196-203
    • Jones, D.C.1    Ding, X.2    Zhang, T.Y.3    Daynes, R.A.4
  • 24
    • 34748917549 scopus 로고    scopus 로고
    • Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor- α
    • Dasgupta S., Roy A., Jana M., Hartley D. M., Pahan K., Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-α Molecular Pharmacology 2007 72 4 934 946
    • (2007) Molecular Pharmacology , vol.72 , Issue.4 , pp. 934-946
    • Dasgupta, S.1    Roy, A.2    Jana, M.3    Hartley, D.M.4    Pahan, K.5
  • 25
    • 0037799205 scopus 로고    scopus 로고
    • Evidence that peroxisome proliferator-activated receptorα is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2
    • Sumanasekera W. K., Tien E. S., Turpey R., Vanden Heuvel J. P., Perdew G. H., Evidence that peroxisome proliferator-activated receptorα is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2 The Journal of Biological Chemistry 2003 278 7 4467 4473
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.7 , pp. 4467-4473
    • Sumanasekera, W.K.1    Tien, E.S.2    Turpey, R.3    Vanden Heuvel, J.P.4    Perdew, G.H.5
  • 26
    • 0042318859 scopus 로고    scopus 로고
    • Heat shock protein-90 (Hsp90) acts as a repressor of peroxisome proliferator-activated receptor-α (PPARα) and PPAR β activity
    • Sumanasekera W. K., Tien E. S., Davis J. W. II, Turpey R., Perdew G. H., Vanden Heuvel J. P., Heat shock protein-90 (Hsp90) acts as a repressor of peroxisome proliferator-activated receptor-α (PPARα) and PPAR β activity Biochemistry 2003 42 36 10726 10735
    • (2003) Biochemistry , vol.42 , Issue.36 , pp. 10726-10735
    • Sumanasekera, W.K.1    Tien, E.S.2    Davis II, J.W.3    Turpey, R.4    Perdew, G.H.5    Vanden Heuvel, J.P.6
  • 28
    • 26444471700 scopus 로고    scopus 로고
    • A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR- γ
    • Pascual G., Fong A. L., Ogawa S., A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR- γ Nature 2005 437 7059 759 763
    • (2005) Nature , vol.437 , Issue.7059 , pp. 759-763
    • Pascual, G.1    Fong, A.L.2    Ogawa, S.3
  • 30
    • 0034711185 scopus 로고    scopus 로고
    • Induction of I κ Bα expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-α activators
    • Delerive P., Gervois P., Fruchart J.-C., Staels B., Induction of I κ Bα expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-α activators The Journal of Biological Chemistry 2000 275 47 36703 36707
    • (2000) The Journal of Biological Chemistry , vol.275 , Issue.47 , pp. 36703-36707
    • Delerive, P.1    Gervois, P.2    Fruchart, J.-C.3    Staels, B.4
  • 32
    • 19544388947 scopus 로고    scopus 로고
    • PPAR-alpha activators suppress STAT1 inflammatory signaling in lipopolysaccharide-activated rat glia
    • Lee J. H., Joe E. H., Jou I., PPAR-alpha activators suppress STAT1 inflammatory signaling in lipopolysaccharide-activated rat glia NeuroReport 2005 16 8 829 833
    • (2005) NeuroReport , vol.16 , Issue.8 , pp. 829-833
    • Lee, J.H.1    Joe, E.H.2    Jou, I.3
  • 33
    • 33748762243 scopus 로고    scopus 로고
    • Fibrates upregulate TRB3 in lymphocytes independent of PPARα by augmenting CCAAT/enhancer-binding protein β (C/EBP β) expression
    • Selim E., Frkanec J. T., Cunard R., Fibrates upregulate TRB3 in lymphocytes independent of PPARα by augmenting CCAAT/enhancer-binding protein β (C/EBP β) expression Molecular Immunology 2007 44 6 1218 1229
    • (2007) Molecular Immunology , vol.44 , Issue.6 , pp. 1218-1229
    • Selim, E.1    Frkanec, J.T.2    Cunard, R.3
  • 34
    • 11144357288 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptorα agonists as therapy for autoimmune disease
    • Lovett-Racke A. E., Hussain R. Z., Northrop S., Peroxisome proliferator-activated receptorα agonists as therapy for autoimmune disease Journal of Immunology 2004 172 9 5790 5798
    • (2004) Journal of Immunology , vol.172 , Issue.9 , pp. 5790-5798
    • Lovett-Racke, A.E.1    Hussain, R.Z.2    Northrop, S.3
  • 35
    • 33847161302 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell-mediated autoimmunity
    • Dunn S. E., Ousman S. S., Sobel R. A., Peroxisome proliferator-activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell-mediated autoimmunity Journal of Experimental Medicine 2007 204 2 321 330
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.2 , pp. 321-330
    • Dunn, S.E.1    Ousman, S.S.2    Sobel, R.A.3
  • 36
    • 25444528680 scopus 로고    scopus 로고
    • Agonists for the peroxisome proliferator-activated receptor-α and the retinoid X receptor inhibit inflammatory responses of microglia
    • Xu J., Storer P. D., Chavis J. A., Racke M. K., Drew P. D., Agonists for the peroxisome proliferator-activated receptor-α and the retinoid X receptor inhibit inflammatory responses of microglia Journal of Neuroscience Research 2005 81 3 403 411
    • (2005) Journal of Neuroscience Research , vol.81 , Issue.3 , pp. 403-411
    • Xu, J.1    Storer, P.D.2    Chavis, J.A.3    Racke, M.K.4    Drew, P.D.5
  • 37
    • 33746079214 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-α and retinoid X receptor agonists inhibit inflammatory responses of astrocytes
    • Xu J., Chavis J. A., Racke M. K., Drew P. D., Peroxisome proliferator-activated receptor-α and retinoid X receptor agonists inhibit inflammatory responses of astrocytes Journal of Neuroimmunology 2006 176 1-2 95 105
    • (2006) Journal of Neuroimmunology , vol.176 , Issue.1-2 , pp. 95-105
    • Xu, J.1    Chavis, J.A.2    Racke, M.K.3    Drew, P.D.4
  • 38
    • 36249015459 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-α agonist fenofibrate regulates IL-12 family cytokine expression in the CNS: Relevance to multiple sclerosis
    • Xu J., Racke M. K., Drew P. D., Peroxisome proliferator-activated receptor-α agonist fenofibrate regulates IL-12 family cytokine expression in the CNS: relevance to multiple sclerosis Journal of Neurochemistry 2007 103 5 1801 1810
    • (2007) Journal of Neurochemistry , vol.103 , Issue.5 , pp. 1801-1810
    • Xu, J.1    Racke, M.K.2    Drew, P.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.