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Volumn 1, Issue SUPPL.3, 2008, Pages

Pathophysiology of parathyroid hyperplasia in chronic kidney disease: Preclinical and clinical basis for parathyroid intervention

Author keywords

Chronic kidney disease; Fibroblast growth factor 23; Parathyroid hyperplasia; Parathyroid intervention; Secondary hyperparathyroidism

Indexed keywords

22 OXACALCITRIOL; ALCOHOL; CALCIMIMETIC AGENT; CALCITRIOL; CALCIUM SENSING RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR 23; PARATHYROID HORMONE; PHOSPHATE; TRANSFORMING GROWTH FACTOR ALPHA; VITAMIN D RECEPTOR;

EID: 48749131218     PISSN: 17530784     EISSN: 17530792     Source Type: Journal    
DOI: 10.1093/ndtplus/sfn079     Document Type: Review
Times cited : (24)

References (84)
  • 1
    • 0343238871 scopus 로고    scopus 로고
    • Cell biology of parathyroid gland hyperplasia in chronic renal failure
    • Drueke TB. Cell biology of parathyroid gland hyperplasia in chronic renal failure. J Am Soc Nephrol 2000; 11: 1141-1152
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1141-1152
    • Drueke, T.B.1
  • 2
    • 33745606947 scopus 로고    scopus 로고
    • Basic and clinical aspects of parathyroid hyperplasia in chronic kidney disease
    • Fukagawa M, Nakanishi S, Kazama JJ. Basic and clinical aspects of parathyroid hyperplasia in chronic kidney disease. Kidney Int 2006; 70(Suppl 102): S3-S7
    • (2006) Kidney Int , vol.70 , Issue.SUPPL. 102
    • Fukagawa, M.1    Nakanishi, S.2    Kazama, J.J.3
  • 3
    • 3543139492 scopus 로고    scopus 로고
    • Mineral metabolism, mortality, and morbidity in maintenance hemodialysis
    • Block GA, Klassen PS, Lazarus JM et al. Mineral metabolism, mortality, and morbidity in maintenance hemodialysis. J Am Soc Nephrol 2004; 15: 2208-2218
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2208-2218
    • Block, G.A.1    Klassen, P.S.2    Lazarus, J.M.3
  • 4
    • 33947264651 scopus 로고    scopus 로고
    • Metabolic bone disease in chronic kidney disease
    • Martin KJ, Gonzalez EA. Metabolic bone disease in chronic kidney disease. J Am Soc Nephrol 2007; 18: 875-885
    • (2007) J Am Soc Nephrol , vol.18 , pp. 875-885
    • Martin, K.J.1    Gonzalez, E.A.2
  • 5
    • 0036714960 scopus 로고    scopus 로고
    • Management of the patients with advanced secondary hyperparathyroidism: The Japanese approach
    • Fukagawa M, Kazama JJ, Shigematsu T. Management of the patients with advanced secondary hyperparathyroidism: the Japanese approach. Nephrol Dial Transplant 2002; 17: 1553-1557
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 1553-1557
    • Fukagawa, M.1    Kazama, J.J.2    Shigematsu, T.3
  • 6
    • 0038015184 scopus 로고    scopus 로고
    • Guideline for percutaneous ethanol injection therapy of the parathyroid glands in chronic dialysis patients
    • Fukagawa M, Kitaoka M, Tominaga Y et al. Guideline for percutaneous ethanol injection therapy of the parathyroid glands in chronic dialysis patients. Nephrol Dial Transplant 2003; 18(Suppl 3): iii31-iii33
    • (2003) Nephrol Dial Transplant , vol.18 , Issue.SUPPL. 3
    • Fukagawa, M.1    Kitaoka, M.2    Tominaga, Y.3
  • 7
    • 0030992925 scopus 로고    scopus 로고
    • Histopathology, pathophysiology, and indications for surgical treatment of renal hyperparathyroidism
    • Tominaga Y, Tanaka Y, Sato K et al. Histopathology, pathophysiology, and indications for surgical treatment of renal hyperparathyroidism. Semin Surg Oncol 1997; 13: 78-86
    • (1997) Semin Surg Oncol , vol.13 , pp. 78-86
    • Tominaga, Y.1    Tanaka, Y.2    Sato, K.3
  • 8
    • 0000434079 scopus 로고
    • Renal osteitis fibrosa cystica. Report of a case with discussion of metabolic aspects
    • Albright F, Drake TG, Sulkowitch HW. Renal osteitis fibrosa cystica. Report of a case with discussion of metabolic aspects. Johns Hopkins Med J 1937; 60: 377-385
    • (1937) Johns Hopkins Med J , vol.60 , pp. 377-385
    • Albright, F.1    Drake, T.G.2    Sulkowitch, H.W.3
  • 9
    • 0014304313 scopus 로고
    • Immunochemical heterogeneity of parathyroid hormone in plasma
    • Berson SA, Yalow RS. Immunochemical heterogeneity of parathyroid hormone in plasma. J Clin Endocrinol Metab 1968; 28: 1037-1047
    • (1968) J Clin Endocrinol Metab , vol.28 , pp. 1037-1047
    • Berson, S.A.1    Yalow, R.S.2
  • 10
    • 0014593947 scopus 로고
    • Circulating parathyroid hormone concentration in chronic renal insufficiency
    • Reiss E, Canterbury JM, Kanter A. Circulating parathyroid hormone concentration in chronic renal insufficiency. Arch Intern Med 1969; 124: 417-422
    • (1969) Arch Intern Med , vol.124 , pp. 417-422
    • Reiss, E.1    Canterbury, J.M.2    Kanter, A.3
  • 11
    • 0015025618 scopus 로고
    • On the pathogenesis of hyperparathyroidism in chronic experimental renal insufficiency in the dog
    • Slatopolsky E, Caglar S, Pennell JP et al. On the pathogenesis of hyperparathyroidism in chronic experimental renal insufficiency in the dog. J Clin Invest 1971; 50: 492-499
    • (1971) J Clin Invest , vol.50 , pp. 492-499
    • Slatopolsky, E.1    Caglar, S.2    Pennell, J.P.3
  • 12
    • 0015514781 scopus 로고
    • On the pathogenesis of the uremic state. An exposition of the 'trade-off hypothesis'
    • Bricker NS. On the pathogenesis of the uremic state. An exposition of the 'trade-off hypothesis'. N Engl J Med 1972; 286: 1093-1099
    • (1972) N Engl J Med , vol.286 , pp. 1093-1099
    • Bricker, N.S.1
  • 13
    • 0015421804 scopus 로고
    • Bone and soft tissue changes with oral phosphate supplements
    • Laflamme GH, Jowsey J. Bone and soft tissue changes with oral phosphate supplements. J Clin Invest 1972; 51: 2834-2840
    • (1972) J Clin Invest , vol.51 , pp. 2834-2840
    • Laflamme, G.H.1    Jowsey, J.2
  • 14
    • 0017738502 scopus 로고
    • Phosphate control and 25-hydroxycholecalciferol administration in preventing experimental renal osteodystrophy in the dog
    • Rutherford WE, Bordier P, Marie P et al. Phosphate control and 25-hydroxycholecalciferol administration in preventing experimental renal osteodystrophy in the dog. J Clin Invest 1977; 60: 332-341
    • (1977) J Clin Invest , vol.60 , pp. 332-341
    • Rutherford, W.E.1    Bordier, P.2    Marie, P.3
  • 15
    • 0021261349 scopus 로고
    • Effect of dietary phosphorus on circulating concentrations of 1,25-dihydroxyvitamin D and immunoreactive parathyroid hormone in children with moderate renal insufficiency
    • Portale AA, Booth BE, Halloran BP et al. Effect of dietary phosphorus on circulating concentrations of 1,25-dihydroxyvitamin D and immunoreactive parathyroid hormone in children with moderate renal insufficiency. J Clin Invest 1984: 73: 1580-1589
    • (1984) J Clin Invest , vol.73 , pp. 1580-1589
    • Portale, A.A.1    Booth, B.E.2    Halloran, B.P.3
  • 16
    • 0021837976 scopus 로고
    • Altered divalent ion metabolism in early renal failure: Role of 1,25(OH)2D
    • Wilson L, Felsenfeld A, Drezner MK et al. Altered divalent ion metabolism in early renal failure: role of 1,25(OH)2D. Kidney Int 1985; 27: 565-573
    • (1985) Kidney Int , vol.27 , pp. 565-573
    • Wilson, L.1    Felsenfeld, A.2    Drezner, M.K.3
  • 17
    • 0022980271 scopus 로고
    • Hypocalcemia may not be essential for the development of secondary hyperparathyroidism in chronic renal failure
    • Lopez-Hilker S, Galceran T, Chan YL et al. Hypocalcemia may not be essential for the development of secondary hyperparathyroidism in chronic renal failure. J Clin Invest 1986; 78: 1097-1102
    • (1986) J Clin Invest , vol.78 , pp. 1097-1102
    • Lopez-Hilker, S.1    Galceran, T.2    Chan, Y.L.3
  • 18
    • 0022350156 scopus 로고
    • 1,25-Dihydroxyvitamin D3 suppresses parathyroid hormone secretion from bovine parathyroid cells in tissue culture
    • Cantley LK, Russell J, Lettieri D et al. 1,25-Dihydroxyvitamin D3 suppresses parathyroid hormone secretion from bovine parathyroid cells in tissue culture. Endocrinology 1985; 117: 2114-2119
    • (1985) Endocrinology , vol.117 , pp. 2114-2119
    • Cantley, L.K.1    Russell, J.2    Lettieri, D.3
  • 19
    • 0022971152 scopus 로고
    • Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat
    • Silver J, Naveh-Many T, Mayer H et al. Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat. J Clin Invest 1986; 78: 1296-1301
    • (1986) J Clin Invest , vol.78 , pp. 1296-1301
    • Silver, J.1    Naveh-Many, T.2    Mayer, H.3
  • 20
    • 0021748474 scopus 로고
    • Marked suppression of secondary hyperparathyroidism by intravenous administration of 1,25-dihydroxy-cholecalciferol in uremic patients
    • Slatopolsky E, Weerts C, Thielan J et al. Marked suppression of secondary hyperparathyroidism by intravenous administration of 1,25-dihydroxy-cholecalciferol in uremic patients. J Clin Invest 1984; 74: 2136-2143
    • (1984) J Clin Invest , vol.74 , pp. 2136-2143
    • Slatopolsky, E.1    Weerts, C.2    Thielan, J.3
  • 21
    • 0024412717 scopus 로고
    • Intravenous calcitriol in the treatment of refractory osteitis fibrosa of chronic renal failure
    • Andress DL, Norris KC, Coburn JW et al. Intravenous calcitriol in the treatment of refractory osteitis fibrosa of chronic renal failure. N Engl J Med 1989; 321: 274-279
    • (1989) N Engl J Med , vol.321 , pp. 274-279
    • Andress, D.L.1    Norris, K.C.2    Coburn, J.W.3
  • 22
    • 0345403572 scopus 로고    scopus 로고
    • 19-Nor-1-alpha-25- dihydroxyvitamin D2 (paricalcitol) safely and effectively reduces the levels of intact parathyroid hormone in patients on hemodialysis
    • Martin KJ, Gonzalez EA, Gellens M et al. 19-Nor-1-alpha-25- dihydroxyvitamin D2 (paricalcitol) safely and effectively reduces the levels of intact parathyroid hormone in patients on hemodialysis. J Am Soc Nephrol 1998; 9: 1427-1432
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1427-1432
    • Martin, K.J.1    Gonzalez, E.A.2    Gellens, M.3
  • 23
    • 8044230723 scopus 로고    scopus 로고
    • Effective suppression of parathyroid hormone by 1 alpha-hydroxy-vitamin D2 in hemodialysis patients with moderate to severe secondary hyperparathyroidism
    • Tan AU Jr, Levine BS, Mazess RB et al. Effective suppression of parathyroid hormone by 1 alpha-hydroxy-vitamin D2 in hemodialysis patients with moderate to severe secondary hyperparathyroidism. Kidney Int 1997; 51: 317-323
    • (1997) Kidney Int , vol.51 , pp. 317-323
    • Tan Jr, A.U.1    Levine, B.S.2    Mazess, R.B.3
  • 24
    • 0022587133 scopus 로고
    • Oral intake of phosphorus can determine the serum concentration of 1,25-dihydroxyvitamin D by determining its production rate in human
    • Portale AA, Halloran BP, Murphy MM et al. Oral intake of phosphorus can determine the serum concentration of 1,25-dihydroxyvitamin D by determining its production rate in human. J Clin Invest 1986; 77: 7-12
    • (1986) J Clin Invest , vol.77 , pp. 7-12
    • Portale, A.A.1    Halloran, B.P.2    Murphy, M.M.3
  • 25
    • 0029070858 scopus 로고
    • Prevention of enhanced parathyroid hormone secretion, synthesis and hyperplasia by mild dietary phosphorus restriction in early chronic renal failure rats: Possible direct role of phosphorus
    • Yi H, Fukagawa M, Yamato H et al. Prevention of enhanced parathyroid hormone secretion, synthesis and hyperplasia by mild dietary phosphorus restriction in early chronic renal failure rats: possible direct role of phosphorus. Nephron 1995; 70: 242-248
    • (1995) Nephron , vol.70 , pp. 242-248
    • Yi, H.1    Fukagawa, M.2    Yamato, H.3
  • 26
    • 0027947478 scopus 로고
    • Phosphorus and protein restriction and parathyroid function in chronic renal failure
    • Combe C, Aparicio M. Phosphorus and protein restriction and parathyroid function in chronic renal failure. Kidney Int 1994; 46: 970-976
    • (1994) Kidney Int , vol.46 , pp. 970-976
    • Combe, C.1    Aparicio, M.2
  • 27
    • 0029887094 scopus 로고    scopus 로고
    • Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro
    • Slatopolsky E, Finch J, Denda M et al. Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro. J Clin Invest 1996; 97: 2534-2540
    • (1996) J Clin Invest , vol.97 , pp. 2534-2540
    • Slatopolsky, E.1    Finch, J.2    Denda, M.3
  • 28
    • 0030012579 scopus 로고    scopus 로고
    • Direct effect of phosphorus on PTH secretion from whole rat parathyroid glands in vitro
    • Almaden Y, Canalejo A, Hernandez A et al. Direct effect of phosphorus on PTH secretion from whole rat parathyroid glands in vitro. J Bone Miner Res 1996; 11: 970-976
    • (1996) J Bone Miner Res , vol.11 , pp. 970-976
    • Almaden, Y.1    Canalejo, A.2    Hernandez, A.3
  • 29
    • 7844250506 scopus 로고    scopus 로고
    • Molecular cloning and hormonal regulation of PiT-1, a sodium-dependent phosphate cotransporter from rat parathyroid glands
    • Tatsumi S, Segawa H, Morita K et al. Molecular cloning and hormonal regulation of PiT-1, a sodium-dependent phosphate cotransporter from rat parathyroid glands. Endocrinology 1998; 139: 1692-1699
    • (1998) Endocrinology , vol.139 , pp. 1692-1699
    • Tatsumi, S.1    Segawa, H.2    Morita, K.3
  • 30
    • 0032708846 scopus 로고    scopus 로고
    • Mechanism of increased parathyroid hormone mRNA in experimental uremia: Roles of protein RNA binding and RNA degradation
    • Yalcindag C, Silver J, Naveh-Many T. Mechanism of increased parathyroid hormone mRNA in experimental uremia: roles of protein RNA binding and RNA degradation. J Am Soc Nephrol 1999; 10: 2562-2568
    • (1999) J Am Soc Nephrol , vol.10 , pp. 2562-2568
    • Yalcindag, C.1    Silver, J.2    Naveh-Many, T.3
  • 31
    • 0034629124 scopus 로고    scopus 로고
    • Identification of AUF1 as a parathyroid hormone mRNA 3′ untranslated region-binding protein that determines parathyroid hormone mRNA stability
    • Sela-Brown A, Silver J, Brewer G et al. Identification of AUF1 as a parathyroid hormone mRNA 3′ untranslated region-binding protein that determines parathyroid hormone mRNA stability. J Biol Chem 2000; 275: 7424-7429
    • (2000) J Biol Chem , vol.275 , pp. 7424-7429
    • Sela-Brown, A.1    Silver, J.2    Brewer, G.3
  • 32
    • 0033843743 scopus 로고    scopus 로고
    • Effect of high extracellular phosphate concentration on arachidonic acid production by parathyroid tissue in vitro
    • Almaden Y, Canalejo A, Ballesteros E et al. Effect of high extracellular phosphate concentration on arachidonic acid production by parathyroid tissue in vitro. J Am Soc Nephrol 2000; 11: 1712-1718
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1712-1718
    • Almaden, Y.1    Canalejo, A.2    Ballesteros, E.3
  • 33
    • 0029160578 scopus 로고
    • A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets
    • The HYP Consortium
    • The HYP Consortium. A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. Nat Genet 1995; 11: 130-136
    • (1995) Nat Genet , vol.11 , pp. 130-136
  • 34
    • 0033763097 scopus 로고    scopus 로고
    • Autosomal dominant hypophosphataemic rickets is associated with mutation in FGF23
    • The ADHR Consortium
    • The ADHR Consortium. Autosomal dominant hypophosphataemic rickets is associated with mutation in FGF23. Nat Genet 2000; 26: 345-348
    • (2000) Nat Genet , vol.26 , pp. 345-348
  • 35
    • 14344279878 scopus 로고    scopus 로고
    • Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
    • Shimada T, Mizutani S, Muto T et al. Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia. Proc Natl Acad Sci USA 2001; 98: 6500-6505
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6500-6505
    • Shimada, T.1    Mizutani, S.2    Muto, T.3
  • 36
    • 15944376583 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men
    • Ferrari SL, Bonjour JP, Rizzoli R. Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men. J Clin Endocrinol Metab 2005; 90: 1519-1524
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1519-1524
    • Ferrari, S.L.1    Bonjour, J.P.2    Rizzoli, R.3
  • 37
    • 23944486382 scopus 로고    scopus 로고
    • Intravenous calcitriol therapy increases serum concentration of fibroblast growth factor 23 in dialysis patients with secondary hyperparathyroidism
    • Nishi H, Nii-Kono T, Nakanishi S et al. Intravenous calcitriol therapy increases serum concentration of fibroblast growth factor 23 in dialysis patients with secondary hyperparathyroidism. Nephron Clin Pract 2005; 101: c94-c99
    • (2005) Nephron Clin Pract , vol.101
    • Nishi, H.1    Nii-Kono, T.2    Nakanishi, S.3
  • 38
    • 19944433609 scopus 로고    scopus 로고
    • Circulating FGF-23 is regulated by 1 alpha, 25-dihydroxyvitamine D3 and phosphate in vivo
    • Saito H, Meda A, Ohtomo S et al. Circulating FGF-23 is regulated by 1 alpha, 25-dihydroxyvitamine D3 and phosphate in vivo. J Biol Chem 2005; 280: 2543-2549
    • (2005) J Biol Chem , vol.280 , pp. 2543-2549
    • Saito, H.1    Meda, A.2    Ohtomo, S.3
  • 39
    • 27444437568 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 is regulated by 1 alpha, 25-dihydroxyvitamin D
    • Collins MT, Lindsay JR, Jain A et al. Fibroblast growth factor-23 is regulated by 1 alpha, 25-dihydroxyvitamin D. J Bone Miner Res 2005; 20: 1944-1950
    • (2005) J Bone Miner Res , vol.20 , pp. 1944-1950
    • Collins, M.T.1    Lindsay, J.R.2    Jain, A.3
  • 41
    • 33845296928 scopus 로고    scopus 로고
    • Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts
    • Masuyama R, Stockmans I, Torrekens S et al. Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts. J Clin Invest 2006; 116: 3150-3159
    • (2006) J Clin Invest , vol.116 , pp. 3150-3159
    • Masuyama, R.1    Stockmans, I.2    Torrekens, S.3
  • 42
    • 36049037977 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitro
    • Perwad F, Zhang MY, Tenenhouse HS et al. Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitro. Am J Physiol Renal Physiol 2007; 293: F1577-F1583
    • (2007) Am J Physiol Renal Physiol , vol.293
    • Perwad, F.1    Zhang, M.Y.2    Tenenhouse, H.S.3
  • 43
    • 0344945402 scopus 로고    scopus 로고
    • Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers
    • Larsson T, Nisbeth U, Ljunggren O et al. Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers. Kidney Int 2003; 64: 2272-2279
    • (2003) Kidney Int , vol.64 , pp. 2272-2279
    • Larsson, T.1    Nisbeth, U.2    Ljunggren, O.3
  • 44
    • 3242661165 scopus 로고    scopus 로고
    • Possible involvement of circulating fibroblast growth factor-23 in the development of secondary hyperparathyroidism associated with renal insufficiency
    • Shigematsu T, Kazama JJ, Yamashita T et al. Possible involvement of circulating fibroblast growth factor-23 in the development of secondary hyperparathyroidism associated with renal insufficiency. Am J Kidney Dis 2004; 44: 250-256
    • (2004) Am J Kidney Dis , vol.44 , pp. 250-256
    • Shigematsu, T.1    Kazama, J.J.2    Yamashita, T.3
  • 45
    • 27744545673 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease
    • Gutierrez O, Isakova T, Rhee E et al. Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease. J Am Soc Nephrol 2005; 16: 2205-2215
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2205-2215
    • Gutierrez, O.1    Isakova, T.2    Rhee, E.3
  • 46
    • 26044452080 scopus 로고    scopus 로고
    • With or without the kidney: The role of FGF23 in CKD
    • Fukagawa M, Kazama JJ. With or without the kidney: the role of FGF23 in CKD. Nephrol Dial Transplant 2005; 20: 1295-1298
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 1295-1298
    • Fukagawa, M.1    Kazama, J.J.2
  • 47
    • 0030904406 scopus 로고    scopus 로고
    • The basal rate of cell proliferation in normal human parathyroid tissue: Implications for the pathogenesis of hyperparathyroidism
    • Wang Q, Palnitkar S, Parfitt AM. The basal rate of cell proliferation in normal human parathyroid tissue: implications for the pathogenesis of hyperparathyroidism. Clin Endocrinol 1997; 46: 343-349
    • (1997) Clin Endocrinol , vol.46 , pp. 343-349
    • Wang, Q.1    Palnitkar, S.2    Parfitt, A.M.3
  • 48
    • 0028858407 scopus 로고
    • Parathyroid cell proliferation in normal and chronic renal failure rats. The effects of calcium, phosphate, and vitamin D
    • Naveh-Many T, Rahaminov R, Livni N et al. Parathyroid cell proliferation in normal and chronic renal failure rats. The effects of calcium, phosphate, and vitamin D. J Clin Invest 1995; 96: 1786-1793
    • (1995) J Clin Invest , vol.96 , pp. 1786-1793
    • Naveh-Many, T.1    Rahaminov, R.2    Livni, N.3
  • 49
    • 0027217909 scopus 로고
    • Decreased 1,25-dihydroxyvitamin D3 receptor density is associated with a more severe formof parathyroid hyperplasia in chronic uremic patients
    • Fukuda N, Tanaka H, Tominaga Y et al. Decreased 1,25-dihydroxyvitamin D3 receptor density is associated with a more severe formof parathyroid hyperplasia in chronic uremic patients. J Clin Invest 1993; 92: 1436-1443
    • (1993) J Clin Invest , vol.92 , pp. 1436-1443
    • Fukuda, N.1    Tanaka, H.2    Tominaga, Y.3
  • 50
    • 0036378184 scopus 로고    scopus 로고
    • Reduced p21, p27 and vitamin D receptor in the nodular hyperplasia in patients with advanced secondary hyperparathyroidism
    • Tokumoto M, Tsuruya K, Fukuda K et al. Reduced p21, p27 and vitamin D receptor in the nodular hyperplasia in patients with advanced secondary hyperparathyroidism. Kidney Int 2002; 62: 1196-1207
    • (2002) Kidney Int , vol.62 , pp. 1196-1207
    • Tokumoto, M.1    Tsuruya, K.2    Fukuda, K.3
  • 51
    • 0029873489 scopus 로고    scopus 로고
    • Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism
    • Kifor O, Moore FD Jr, Wang P et al. Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism. J Clin Endocrinol Metab 1996; 81: 1598-1606
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1598-1606
    • Kifor, O.1    Moore Jr, F.D.2    Wang, P.3
  • 52
    • 0031042732 scopus 로고    scopus 로고
    • Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism
    • Gogusev J, Duchambon P, Hory B et al. Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism. Kidney Int 1997; 51: 328-336
    • (1997) Kidney Int , vol.51 , pp. 328-336
    • Gogusev, J.1    Duchambon, P.2    Hory, B.3
  • 53
    • 0035094077 scopus 로고    scopus 로고
    • p21(WAF1) and transforming growth factor-alpha mediate dietary phosphate regulation of parathyroid cell growth
    • Dusso AS, Pavlopoulos T, Naumovich L et al. p21(WAF1) and transforming growth factor-alpha mediate dietary phosphate regulation of parathyroid cell growth. Kidney Int 2001; 59: 855-865
    • (2001) Kidney Int , vol.59 , pp. 855-865
    • Dusso, A.S.1    Pavlopoulos, T.2    Naumovich, L.3
  • 54
    • 33745609231 scopus 로고    scopus 로고
    • Pathogenic mechanisms for parathyroid hyperplasia
    • Dusso AS, Sato T, Arcidiacono MV et al. Pathogenic mechanisms for parathyroid hyperplasia. Kidney Int 2006; 70(Suppl 102): S8-S11
    • (2006) Kidney Int , vol.70 , Issue.SUPPL. 102
    • Dusso, A.S.1    Sato, T.2    Arcidiacono, M.V.3
  • 55
    • 39049148171 scopus 로고    scopus 로고
    • EGFR activation increases parathyroid hyperplasia and calcitriol resistance in kidney disease
    • Arcidiacono MV, Sato T, Alvarez-Hernandez D et al. EGFR activation increases parathyroid hyperplasia and calcitriol resistance in kidney disease. J Am Soc Nephrol 2008; 19: 310-320
    • (2008) J Am Soc Nephrol , vol.19 , pp. 310-320
    • Arcidiacono, M.V.1    Sato, T.2    Alvarez-Hernandez, D.3
  • 56
    • 0028946265 scopus 로고
    • Monoclonality of parathyroid tumors in chronic renal failure and in primary parathyroid hyperplasia
    • Arnold A, Brown MF, Urena P et al. Monoclonality of parathyroid tumors in chronic renal failure and in primary parathyroid hyperplasia. J Clin Invest 1995; 95: 2047-2053
    • (1995) J Clin Invest , vol.95 , pp. 2047-2053
    • Arnold, A.1    Brown, M.F.2    Urena, P.3
  • 57
    • 20844459989 scopus 로고    scopus 로고
    • Serum fibroblast growth factor-23 levels predict the future refractory hyperparathyroidism in dialysis patients
    • Nakanishi S, Kazama JJ, Nii-Kono T et al. Serum fibroblast growth factor-23 levels predict the future refractory hyperparathyroidism in dialysis patients. Kidney Int 2005; 67: 1171-1178
    • (2005) Kidney Int , vol.67 , pp. 1171-1178
    • Nakanishi, S.1    Kazama, J.J.2    Nii-Kono, T.3
  • 58
    • 20844461345 scopus 로고    scopus 로고
    • Pretreatment serum FGF-23 levels predict the efficacy of calcitriol therapy in dialysis patients
    • Kazama JJ, Sato F, Omori K et al. Pretreatment serum FGF-23 levels predict the efficacy of calcitriol therapy in dialysis patients. Kidney Int 2005; 67: 1120-1125
    • (2005) Kidney Int , vol.67 , pp. 1120-1125
    • Kazama, J.J.1    Sato, F.2    Omori, K.3
  • 59
    • 4444308167 scopus 로고    scopus 로고
    • Total parathyroidectomy reduces elevated circulating fibroblast growth factor 23 in advanced secondary hyperparathyroidism
    • Sato T, Tominaga Y, Ueki T et al. Total parathyroidectomy reduces elevated circulating fibroblast growth factor 23 in advanced secondary hyperparathyroidism. Am J Kidney Dis 2004; 44: 481-487
    • (2004) Am J Kidney Dis , vol.44 , pp. 481-487
    • Sato, T.1    Tominaga, Y.2    Ueki, T.3
  • 60
    • 37249064862 scopus 로고    scopus 로고
    • Bone mass does not correlate with the serum fibroblast growth factor 23 in hemodialysis patients
    • Urena-Torres P, Friedlander G, de Vernejoul MC et al. Bone mass does not correlate with the serum fibroblast growth factor 23 in hemodialysis patients. Kidney Int 2008; 73: 102-107
    • (2008) Kidney Int , vol.73 , pp. 102-107
    • Urena-Torres, P.1    Friedlander, G.2    de Vernejoul, M.C.3
  • 61
    • 0034613242 scopus 로고    scopus 로고
    • Fibroblast growth factor (FGF)-2 directly stimulates mature osteoclast function through activation of FGF receptor 1 and p42/p44 MAP kinase
    • Chikazu D, Hakeda Y, Ogata N et al. Fibroblast growth factor (FGF)-2 directly stimulates mature osteoclast function through activation of FGF receptor 1 and p42/p44 MAP kinase. J Biol Chem 2000; 275: 31444-31450
    • (2000) J Biol Chem , vol.275 , pp. 31444-31450
    • Chikazu, D.1    Hakeda, Y.2    Ogata, N.3
  • 62
    • 33646578195 scopus 로고    scopus 로고
    • Regulation of fibroblast growth factor-23 signaling by klotho
    • Kurosu H, Ogawa Y, Miyoshi M et al. Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem 2006; 281: 6120-6123
    • (2006) J Biol Chem , vol.281 , pp. 6120-6123
    • Kurosu, H.1    Ogawa, Y.2    Miyoshi, M.3
  • 63
    • 33845631059 scopus 로고    scopus 로고
    • Klotho converts canonical FGF receptor into a specific receptor for FGF23
    • Urakawa I, Yamazaki Y, Shimada T et al. Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 2006; 444: 770-774
    • (2006) Nature , vol.444 , pp. 770-774
    • Urakawa, I.1    Yamazaki, Y.2    Shimada, T.3
  • 64
    • 36849017126 scopus 로고    scopus 로고
    • The parathyroid is a target organ for FGF23 in rats
    • Ben-Dov IZ, Galitzer H, Lavi-Moshayoff V et al. The parathyroid is a target organ for FGF23 in rats. J Clin Invest 2007; 117: 4003-4008
    • (2007) J Clin Invest , vol.117 , pp. 4003-4008
    • Ben-Dov, I.Z.1    Galitzer, H.2    Lavi-Moshayoff, V.3
  • 65
    • 0025366115 scopus 로고
    • Regression of parathyroid hyperplasia by calcitriol-pulse therapy in patients on long-term dialysis
    • Fukagawa M, Okazaki R, Takano K et al. Regression of parathyroid hyperplasia by calcitriol-pulse therapy in patients on long-term dialysis. N Engl J Med 1990; 323: 421-422
    • (1990) N Engl J Med , vol.323 , pp. 421-422
    • Fukagawa, M.1    Okazaki, R.2    Takano, K.3
  • 66
    • 4544272984 scopus 로고    scopus 로고
    • Infarction of mediastinal parathyroid gland causing spontaneous remission of secondary hyperparathyroidism
    • Tanaka M, Tominaga Y, Sawatari E et al. Infarction of mediastinal parathyroid gland causing spontaneous remission of secondary hyperparathyroidism. Am J Kidney Dis 2004; 44: 762-767
    • (2004) Am J Kidney Dis , vol.44 , pp. 762-767
    • Tanaka, M.1    Tominaga, Y.2    Sawatari, E.3
  • 67
    • 44449163362 scopus 로고    scopus 로고
    • Spontaneous remission of severe hyperparathyroidism with normalization of the reversed whole PTH/intact PTH ratio in a haemodialysis patient
    • Komaba H, Takeda Y, Abe T et al. Spontaneous remission of severe hyperparathyroidism with normalization of the reversed whole PTH/intact PTH ratio in a haemodialysis patient. Nephrol Dial Transplant 2008; 23: 1760-1762
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 1760-1762
    • Komaba, H.1    Takeda, Y.2    Abe, T.3
  • 68
    • 0027983607 scopus 로고
    • Serial evaluation of parathyroid size by ultrasonography is another useful marker for the long-term prognosis of calcitriol pulse therapy in chronic dialysis patient
    • Fukagawa M, Kitaoka M, Yi H et al. Serial evaluation of parathyroid size by ultrasonography is another useful marker for the long-term prognosis of calcitriol pulse therapy in chronic dialysis patient. Nephron 1994; 68: 221-228
    • (1994) Nephron , vol.68 , pp. 221-228
    • Fukagawa, M.1    Kitaoka, M.2    Yi, H.3
  • 69
    • 10744230203 scopus 로고    scopus 로고
    • Relationship between parathyroid gland size and responsiveness to maxacalcitol therapy in patients with secondary hyperparathyroidism
    • Okuno S, Ishimura E, Kitatani K et al. Relationship between parathyroid gland size and responsiveness to maxacalcitol therapy in patients with secondary hyperparathyroidism. Nephrol Dial Transplant 2003; 18: 2613-2621
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 2613-2621
    • Okuno, S.1    Ishimura, E.2    Kitatani, K.3
  • 70
    • 33646268180 scopus 로고    scopus 로고
    • Is the volume of the parathyroid gland a predictor of Maxacalcitol response in advanced secondary hyperparathyroidism?
    • Tominaga Y, Inaguma D, Matsuoka S et al. Is the volume of the parathyroid gland a predictor of Maxacalcitol response in advanced secondary hyperparathyroidism? Ther Apher Dial 2006; 10: 198-204
    • (2006) Ther Apher Dial , vol.10 , pp. 198-204
    • Tominaga, Y.1    Inaguma, D.2    Matsuoka, S.3
  • 71
    • 0034806084 scopus 로고    scopus 로고
    • More than 1,000 cases of total parathyroidectomy with forearm autograft for renal hyperparathyroidism
    • Tominaga Y, Uchida K, Haba T et al. More than 1,000 cases of total parathyroidectomy with forearm autograft for renal hyperparathyroidism. Am J Kidney Dis 2001; 38(Suppl l): S166-S171
    • (2001) Am J Kidney Dis , vol.38 , Issue.SUPPL. L
    • Tominaga, Y.1    Uchida, K.2    Haba, T.3
  • 72
    • 33846660496 scopus 로고    scopus 로고
    • Efficacy of percutaneous ethanol injection therapy (PEIT) is related to the number of parathyroid glands in haemodialysis patients with secondary hyperparathyroidism
    • Koiwa F, Kakuta T, Tanaka R et al. Efficacy of percutaneous ethanol injection therapy (PEIT) is related to the number of parathyroid glands in haemodialysis patients with secondary hyperparathyroidism. Nephrol Dial Transplant 2007; 22: 522-528
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 522-528
    • Koiwa, F.1    Kakuta, T.2    Tanaka, R.3
  • 73
    • 84981641604 scopus 로고
    • Direct injections of calciriol into parathyroid hyperplasia in chronic dialysis patients with severe parathyroid hyperfunction
    • Kitaoka M, Fukagawa M, Fukuda N et al. Direct injections of calciriol into parathyroid hyperplasia in chronic dialysis patients with severe parathyroid hyperfunction. Nephrology 1995; 1: 563-568
    • (1995) Nephrology , vol.1 , pp. 563-568
    • Kitaoka, M.1    Fukagawa, M.2    Fukuda, N.3
  • 74
    • 0038691679 scopus 로고    scopus 로고
    • Percutaneous calcitriol injection therapy (PCIT) for secondary hyperparathyroidism: Multicenter trial
    • Kitaoka M, Onoda NM, Kitamura H et al. Percutaneous calcitriol injection therapy (PCIT) for secondary hyperparathyroidism: multicenter trial. Nephrol Dial Transplant 2003; 18(Suppl 3): iii38-iii41
    • (2003) Nephrol Dial Transplant , vol.18 , Issue.SUPPL. 3
    • Kitaoka, M.1    Onoda, N.M.2    Kitamura, H.3
  • 75
    • 0041429578 scopus 로고    scopus 로고
    • Percutaneous maxacalcitol injection therapy regresses hyperplasia of parathyroid and induces apoptosis in uremia
    • Shiizaki K, Hatamura I, Negi S et al. Percutaneous maxacalcitol injection therapy regresses hyperplasia of parathyroid and induces apoptosis in uremia. Kidney Int 2003; 64: 992-1003
    • (2003) Kidney Int , vol.64 , pp. 992-1003
    • Shiizaki, K.1    Hatamura, I.2    Negi, S.3
  • 76
    • 20844462329 scopus 로고    scopus 로고
    • Biochemical and cellular effect of direct maxacalcitol injection into parathyroid gland in uremic rat
    • Shiizaki K, Negi S, Hatamura I et al. Biochemical and cellular effect of direct maxacalcitol injection into parathyroid gland in uremic rat. J Am Soc Nephrol 2005; 16: 97-108
    • (2005) J Am Soc Nephrol , vol.16 , pp. 97-108
    • Shiizaki, K.1    Negi, S.2    Hatamura, I.3
  • 77
    • 17144387916 scopus 로고    scopus 로고
    • 2+ for drug development: The extracellular calcium receptor and an innovative medical approach to control secondary hyperparathyroidism by calcimimetics
    • 2+ for drug development: the extracellular calcium receptor and an innovative medical approach to control secondary hyperparathyroidism by calcimimetics. J Pharmacol Sci 2005; 97: 355-360
    • (2005) J Pharmacol Sci , vol.97 , pp. 355-360
    • Nagano, N.1    Nemeth, E.F.2
  • 78
    • 11144353767 scopus 로고    scopus 로고
    • Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis
    • Block GA, Martin KJ, de Francisco AL et al. Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis. N Engl J Med 2004; 350: 1516-1525
    • (2004) N Engl J Med , vol.350 , pp. 1516-1525
    • Block, G.A.1    Martin, K.J.2    de Francisco, A.L.3
  • 79
    • 20544460709 scopus 로고    scopus 로고
    • Cinacalcet HCl, an oral calcimimetic agent for the treatment of secondary hyperparathyroidism in hemodialysis and peritoneal dialysis: A randomized, double-blind, multicenter study
    • Lindberg JS, Culleton B, Wong G et al. Cinacalcet HCl, an oral calcimimetic agent for the treatment of secondary hyperparathyroidism in hemodialysis and peritoneal dialysis: a randomized, double-blind, multicenter study. J Am Soc Nephrol 2005; 16: 800-807
    • (2005) J Am Soc Nephrol , vol.16 , pp. 800-807
    • Lindberg, J.S.1    Culleton, B.2    Wong, G.3
  • 80
    • 44449098194 scopus 로고    scopus 로고
    • Cinacalcet (KRN1493) effectively decreases the serum intact PTH level with favorable control of the serum phosphorus and calcium levels in Japanese dialysis patients
    • Fukagawa M, Yumita S, Akizawa T et al. Cinacalcet (KRN1493) effectively decreases the serum intact PTH level with favorable control of the serum phosphorus and calcium levels in Japanese dialysis patients. Nephrol Dial Transplant 2008; 23: 328-335
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 328-335
    • Fukagawa, M.1    Yumita, S.2    Akizawa, T.3
  • 81
    • 33745607742 scopus 로고    scopus 로고
    • Improvement in hypercalcemia with cinacalcet after kidney transplantation
    • Srinivas TR, Schold JD, Womer KL et al. Improvement in hypercalcemia with cinacalcet after kidney transplantation. Clin J Am Soc Nephrol 2006; 1: 323-326
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 323-326
    • Srinivas, T.R.1    Schold, J.D.2    Womer, K.L.3
  • 82
    • 33846694280 scopus 로고    scopus 로고
    • Effective control of persistent hyperparathyroidism with cinacalcet in renal allograft recipients
    • Serra AL, Savoca R, Huber AR et al. Effective control of persistent hyperparathyroidism with cinacalcet in renal allograft recipients. Nephrol Dial Transplant 2007; 22: 577-583
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 577-583
    • Serra, A.L.1    Savoca, R.2    Huber, A.R.3
  • 83
    • 34547830303 scopus 로고    scopus 로고
    • Effect of cinacalcet cessation in renal transplant recipients with persistent hyperparathyroidism
    • Kruse AE, Eisenberger U, Frey FJ et al. Effect of cinacalcet cessation in renal transplant recipients with persistent hyperparathyroidism. Nephrol Dial Transplant 2007; 22: 2362-2365
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 2362-2365
    • Kruse, A.E.1    Eisenberger, U.2    Frey, F.J.3
  • 84
    • 33746157756 scopus 로고    scopus 로고
    • Persistent hyperparathyroidism in renal allograft recipients: Vitamin D receptor, calcium-sensing receptor, and apoptosis
    • Taniguchi M, Tokumoto M, Matuo D et al. Persistent hyperparathyroidism in renal allograft recipients: vitamin D receptor, calcium-sensing receptor, and apoptosis. Kidney Int 2006; 70: 363-370
    • (2006) Kidney Int , vol.70 , pp. 363-370
    • Taniguchi, M.1    Tokumoto, M.2    Matuo, D.3


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