Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 16, 2008, Pages 4544-4546

  Lee, Seung Woong ^a   Kim, Young Kook ^a   Kim, Koanhoi ^b   Lee, Hyun Sun ^a   Choi, Jung Ho ^a   Lee, Woo Song ^a   Jun, Chang Duk ^c   Park, Jee Hun ^d   Lee, Jeong Min ^d   Rho, Mun Chual ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

^c Gwangju Institute of Science and Technology (GIST)   (South Korea)

^d Sinil Pharmaceutical Co   (South Korea)

Author keywords

Alkamides; Cell adhesion molecules; Piper longum L.; Piper nigum L.; Piperaceae; THP 1 cells

Indexed keywords

DEHYDROPIPERNONALINE; GUINEENSINE; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; N [9 (3,4 METHYLENEDIOXYPHENYL) 2,4,8 NONATRIENOYL]PIPERIDINE; PELLITORIN; PIPERCHABAMIDE B; PIPERNONALINE; PIPERROLEIN B; PLANT EXTRACT; RETROFRACAMIDE; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; BLACK PEPPER; CARBON NUCLEAR MAGNETIC RESONANCE; CELL ADHESION; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FRUIT; HUMAN; HUMAN CELL; IC 50; PIPER LONGUM; PIPERACEAE; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY;

BIOLOGICAL ASSAY; CELL ADHESION; CELL LINE; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; ETHANOL; HUMANS; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; PIPER; PIPER NIGRUM; PLANT EXTRACTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY;

PIPER LONGUM; PIPER NIGRUM; PIPERACEAE;

EID: 48749130607     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.07.045     Document Type: Article

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