The rewarding efficacy of brain stimulation and its modulation by dopaminergic drugs in young adult and old BN F344F1 rats

Pharmacology Biochemistry and Behavior

Volumn 90, Issue 4, 2008, Pages 735-741

  Sonnenschein, Bonnie ^a   Franklin, Keith B J ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Aged; Aging; Alpha methyl p tyrosine; Amphetamine; Dopamine; Rate frequency curve; Reinforcement; Rewarding brain stimulation

Indexed keywords

ACETYLCHOLINE; DEXAMPHETAMINE; DOPAMINE; DOPAMINE RECEPTOR STIMULATING AGENT; METIROSINE; MYELIN;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; DOPAMINE BRAIN LEVEL; DOPAMINERGIC SYSTEM; DOPAMINERGIC TRANSMISSION; DRUG EFFECT; FREQUENCY ANALYSIS; MALE; MENTAL PERFORMANCE; MOOD CHANGE; MOTIVATION; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; REINFORCEMENT; REWARD; STATISTICAL ANALYSIS;

AGING; ALPHA-METHYLTYROSINE; ANIMALS; BRAIN; BRAIN CHEMISTRY; CONDITIONING, OPERANT; DEXTROAMPHETAMINE; DOPAMINE AGENTS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ENZYME INHIBITORS; RATS; RATS, INBRED F344; REINFORCEMENT SCHEDULE; REWARD;

ANIMALIA; RATTUS;

EID: 48749116825     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2008.06.001     Document Type: Article

References (74)

1. Ainslie P.N., Campbell I.T., Frayn K.N., Humphreys S.M., MacLaren D.P., Reilly T., et al. Energy balance, metabolism, hydration, and performance during strenuous hill walking: the effect of age. J Appl Physiol 93 (2002) 714-723
2. Arnsten A.F., Cai J.X., Murphy B.L., and Goldman-Rakic P.S. Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys. Psychopharmacol 116 (1994) 143-151
3. Backman L., Ginovart N., Dixon R.A., Wahlin T.B., Wahlin A., Halldin C., et al. Age-related cognitive deficits mediated by changes in the striatal dopamine system. Am J Psychiat 157 (2000) 635-637
4. Birkmayer W. The importance of monoamine metabolism for the pathology of the extrapyramidal system. J. Neuro-Visc. Relat. 31 (1969) Suppl
5. Bossert J.M., and Franklin K.B. Reinforcing versus anticonvulsant drugs: effects on intracranial self-stimulation rate-frequency M50 indices. Behav Brain Res 144 (2003) 243-247
6. Breese G.R., Cooper B.R., and Smith R.D. Biochemical and behavioural alterations following 6-hydroxydopamine administration into brain. In: Usdin E., and Snyder S.H. (Eds). Frontiers in catecholamine research (1973), Pergamon Press, New York 701-706 Ref Type: Serial (Book, Monograph)
7. Carfagna N., Trunzo F., and Moretti A. Brain catecholamine content and turnover in aging rats. Exp Gerontol 20 (1985) 265-269
8. Conover K.L., and Shizgal P. Competition and summation between rewarding effects of sucrose and lateral hypothalamic stimulation in the rat. Behav Neurosci 108 (1994) 537-548
9. Copeland J.R., Beekman A.T., Dewey M.E., Jordan A., Lawlor B.A., Linden M., et al. Cross-cultural comparison of depressive symptoms in Europe does not support stereotypes of ageing. Br J Psychiatry 174 (1999) 322-329
10. Coulombe D., and Miliaressis E. Fitting intracranial self-stimulation data with growth models. Behav Neurosci 101 (1987) 209-214
11. DeWit D.J., Offord D.R., and Wong M. Patterns of onset and cessation of drug use over the early part of the life course. Health Educ Behav 24 (1997) 746-758
12. Dobrev D., Bergstrasser E., Fischer H.D., and Andreas K. Restriction and functional changes of dopamine release in rat striatum from young adult and old rats. Mech Aging Devel 80 (1995) 107-119
13. Dominic J.A., and Moore K.E. Acute effects of alpha-methyltyrosine on brain catecholamine levels and on spontaneous and amphetamine-stimulated motor activity in mice. Arch Int Pharmacodyn Ther 178 (1969) 166-176
14. Dowling G.J., Weiss S.R., and Condon T.P. Drugs of abuse and the aging brain. Neuropsychopharmacology 33 (2008) 209-218
15. Edmonds D.E., and Gallistel C.R. Reward versus performance effects in self-stimulation: electrode-specific effects of α-methyl-p-tyrosine on reward in the rat. J Comp Physiol Psychol 91 (1977) 962-974
16. Edmonds D.E., Stellar J.R., and Gallistel C.R. Parametric analysis of brain stimulation reward in the rat: II. Temporal summation in the reward system. J Comp Physiol Psychol 87 (1974) 860-869
17. Fibiger H.C., Phillips A.G., and Brown E.E. The neurobiology of cocaine-induced reinforcement. Ciba Found. Symp. 166 (1992) 96-111 discu
18. Fouriezos G., and Wise R.A. Pimozide-induced extinction of intracranial self-stimulation: response patterns rule out motor deficit. Brain Res 380 (1976) 377-380
19. Franklin K.B.J. Catecholamines and self-stimulation: reward and performance effects dissociated. Pharmacol Biochem Behav 9 (1978) 813-820
20. Franklin K.B.J., and Herberg L.J. Self-stimulation and catecholamines: drug induced mobilization of the 'reserve'-pool re-establishes responding in catecholamine depleted rats. Brain Res 67 (1974) 429-437
21. Friedemann M.N., and Gerhardt G.A. Regional effects of aging on dopaminergic function in the Fischer-344 rat. Neurobiol Aging 13 (1992) 325-332
22. Gallistel C.R., and Beagley G. Specificity of brain stimulation reward in the rat. J Comp Physiol Psychol 76 (1971) 199-205
23. Gallistel C.R., and Freyd G. Quantitative determination of the effects of catecholamine agonists and antagonists on the rewarding efficacy of brain stimulation. Pharmacol Biochem Behav 26 (1987) 731-741
24. Gallistel C.R., Shizgal P., and Yeomans J.S. A portrait of the substrate for self-stimulation. Psychol Rev 88 (1981) 228-273
25. Gallo J.J., and Lebowitz B.D. The epidemiology of common late-life mental disorders in the community: themes for the new century. Psychiatr. serv. 50 (1999) 1158-1166
26. Garris P.A., Kilpatrick M., Bunin M.A., Michael D., Walker Q.D., and Wightman R.M. Dissociation of dopamine release in the nucleus accumbens from intracranial self-stimulation. Nature 398 (1999) 67-69
27. Gfroerer J., Penne M., Pemberton M., and Folsom R. Substance abuse treatment need among older adults in 2020: the impact of the aging baby-boom cohort. Drug Alcohol Depend 69 (2003) 127-135
28. Gibson S., McGeer E.G., and McGeer P.L. The effect of selective inhibitors of tyrosine and tryptophan hydroxylases on self-stimulation in the rat. Exp Neurol 27 (1970) 283-290
29. Godefroy F., Bassant M.H., Weil-Fugazza J., and Lamour Y. Age-related changes in dopaminergic and serotonergic indices in the rat forebrain. Neurobiol Aging 10 (1989) 187-190
30. Gozlan H., Daval G., Verge D., Spampinato U., Fattaccini C.M., Gallissot M.C., et al. Aging associated changes in serotoninergic and dopaminergic pre- and postsynaptic neurochemical markers in the rat brain. Neurobiol Aging 11 (1990) 437-449
31. Greenwood C.E., Tatton W.G., Seniuk N.A., and Biddle F.G. Increased dopamine synthesis in aging substantia nigra neurons. Neurobiol Aging 12 (1991) 557-565
32. Han Z., Kuyatt B.L., Kochman K.A., DeSouza E.B., and Roth G.S. Effect of aging on concentrations of D2-receptor-containing neurons in the rat striatum. Brain Res 498 (1989) 299-307
33. Hand T.H., and Franklin K.B.J. The influence of amphetamine on preference for lateral hypothalamic versus prefrontal cortex or ventral tegmental area self-stimulation. Pharmacol Biochem Behav 18 (1983) 695-699
34. Haycock J.W., Becker L., Ang L., Furukawa Y., Hornykiewicz O., and Kish S.J. Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum. J Neurochem 87 (2003) 574-585
35. Hebert M.A., and Gerhardt G.A. Normal and drug-induced locomotor behavior in aging: comparison to evoked DA release and tissue content in Fischer 344 rats. Brain Res 797 (1998) 42-54
36. Jha S.H., Knapp C.M., and Kornetsky C. Effects of morphine on brain-stimulation reward thresholds in young and aged rats. Pharmacol Biochem Behav 79 (2004) 483-490
37. Kenney W.L., and Chiu P. Influence of age on thirst and fluid intake. Med sci sports exerc 33 (2001) 1524-1532
38. Lee J.J., Chang C.K., Liu I.M., Chi T.C., Yu H.J., and Cheng J.T. Changes in endogenous monoamines in aged rats. Clin Exp Pharmacol Physiol 28 (2001) 285-289
39. Lepore M., and Franklin K.B.J. Modelling drug kinetics with brain stimulation: dopamine antagonists increase self-stimulation. Pharmacol Biochem Behav 41 (1992) 489-496
40. Lewis M.J. Age-related decline in brain stimulation reward: rejuvenation by amphetamine. Exp aging res 7 (1981) 225-234
41. Mattison J.A., Black A., Huck J., Moscrip T., Handy A., Tilmont E., et al. Age-related decline in caloric intake and motivation for food in Rhesus monkeys. Neurobiol Aging 26 (2005) 1117-1127
42. Moll, G.H., Mehnert, C., Wicker, M., Bock, N., Rothenberger, A., Ruther, E.et al. Age-associated changes in the densities of presynaptic monoamine transporters in different regions of the rat brain from early juvenile life to late adulthood. Brain Res. 2000; Developmental Brain Research. 119: 251-257.
43. Mowe M., Bohmer T., and Kindt E. Reduced nutritional status in an elderly population (> 70 y) is probable before disease and possibly contributes to the development of disease. Am j clin nutr 59 (1994) 317-324 [erratum appears in Am J Clin Nutr 1994 Aug;60(2):298]
44. Mulligan T., and Moss C.R. Sexuality and aging in male veterans: a cross-sectional study of interest, ability, and activity. Arch Sex Behav 20 (1991) 17-25
45. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates (1998), Academic Press, Sydney
46. Pert A., and Hulsebus P. Effect of morphine on intracranial self-stimulation behavior following brain amine depletion. Life Sci 17 (1975) 19-20
47. Peters A. Structural changes that occur during normal aging of primate cerebral hemispheres. Neurosci Biobehav Rev 26 (2002) 733-741
48. Ponzio F., Calderini G., Lomuscio G., Vantini G., Toffano G., and Algeri S. Changes in monoamines and their metabolite levels in some brain regions of aged rats. Neurobiol Aging 3 (1982) 23-29
49. Poschel B.P.H., and Ninteman F.W. Intracranial reward and the forebrain's serotonergic mechanism: studies employing para-chlorophenylalanine and para-chloroamphetamine. Physiol Behav 7 (1971) 39-46
50. Price R.K., Risk N.K., and Spitznagel E.L. Remission from drug abuse over a 25-year period: patterns of remission and treatment use. Am J Publ Health 91 (2001) 1107-1113
51. Prince M.J., Beekman A.T., Deeg D.J., Fuhrer R., Kivela S.L., Lawlor B.A., et al. Depression symptoms in late life assessed using the EURO-D scale. Effect of age, gender and marital status in 14 European centres. Brit J Psychiat 174 (1999) 339-345 [see comment]
52. Purdom M.S., Stanford J.A., Currier T.D., and Gerhardt G.A. Microdialysis studies of d-amphetamine-evoked striatal dopamine overflow in young versus aged F344 rats: effects of concentration and order of administration. Brain Res 979 (2003) 203-209
53. Purifoy F.E., Grodsky A., and Giambra L.M. The relationship of sexual daydreaming to sexual activity, sexual drive, and sexual attitudes for women across the life-span. Arch Sex Behav 21 (1992) 369-385
54. Rolls B.J., Dimeo K.A., and Shide D.J. Age-related impairments in the regulation of food intake. Am j clin nutr 62 (1995) 923-931
55. Sawka M.N., and Montain S.J. Fluid and electrolyte supplementation for exercise heat stress. Am j clin nutr 72 (2000) 564S-572S
56. Scherman D., Desnos C., Darchen F., Pollak P., Javoy-Agid F., and Agid Y. Striatal dopamine deficiency in Parkinson's disease: role of aging. Ann Neurol 26 (1989) 551-557
57. Shui H.A., Peng Y.I., and Tsai Y.F. Recovery of high potassium-evoked dopamine release after depolarization challenge in the striatum of young and old male rats. Neurosci Lett 257 (1998) 1-4 [erratum appears in Neurosci Lett 1999 Aug 13;271(1):68]
58. 1 hybrid. Neurobiol Aging 15 (1994) 319-328
59. Spyraki C., Fibiger H.C., and Phillips A.G. Attenuation of heroin reward in rats by disruption of the mesolimbic dopamine system. Psychopharmacol 79 (1983) 278-283
60. Stinus L., Le Moal M., and Cardo B. Autostimulation et catécholamines. I Intervention possible des deux "compartiments" (compartiment fonctionnel; et compatiment de réserve). Physiol Behav 9 (1972) 175-182
61. Suzuki M., Hatano K., Sakiyama Y., Kawasumi Y., Kato T., and Ito K. Age-related changes of dopamine D1-like and D2-like receptor binding in the F344/N rat striatum revealed by positron emission tomography and in vitro receptor autoradiography. Synapse 41 (2001) 285-293
62. Tanila H., Taira T., Piepponen T.P., and Honkanen A. Effect of sex and age on brain monoamines and spatial learning in rats. Neurobiol Aging 15 (1994) 733-741
63. Thunhorst R.L., and Johnson A.K. Thirst and salt appetite responses in young and old Brown Norway rats. Am J Physiol - Regul Integr Comp Physiol 284 (2003) R317-R327
64. Turturro A., Witt W.W., Lewis S., Hass B.S., Lipman R.D., and Hart R.W. Growth curves and survival characteristics of the animals used in the Biomarkers of Aging Program. J Gerontol A Biol Sci Med Sci 54 (1999) B492-B501
65. US Department of Health and Human Services. National survey on drug use and health (2004) Ref Type: Report
66. Vaillant G.E. A 20 year follow up of New York narcotics drug addicts. Arch Gen Psychiatry 29 (1978) 237-241
67. Volkow N.D., Ding Y.S., Fowler J.S., Wang G.J., Logan J., Gatley S.J., et al. Dopamine transporters decrease with age. J nucl med 37 (1996) 554-559
68. Weindruch R., and Masoro E.J. Concerns about rodent models for aging research. J Gerontol 46 (1991) B87-B88
69. Widerlov E., Lewander T., Widerlov E., and Lewander T. Inhibition of the in vivo biosynthesis and changes of catecholamine levels in rat brain after alpha-methyl-p-tyrosine; time- and dose-response relationships. Naunyn-Schmiedeberg's arch pharmacol 304 (1978) 111-123
70. Winick C. Maturing out of narcotic addiction. Bull Narc 14 (1962) 1-7
71. Wise R.A. The role of reward pathways in the development of drug dependence. Pharmacol Ther 35 (1987) 227-263
72. Wise R.A. Psychomotor stimulant properties of addictive drugs. Ann NY Acad Sci 537 (1988) 228-234
73. Yoshimoto K., Yoshida T., Sorimachi Y., Hirano A., Takeuchi Y., Ueda S., et al. Effects of age and ethanol on dopamine and serotonin release in the rat nucleus accumbens. Physiol Behav 64 (1998) 347-351
74. Yurek D.M., Hipkens S.B., Hebert M.A., Gash D.M., and Gerhardt G.A. Age-related decline in striatal dopamine release and motoric function in brown Norway/Fischer 344 hybrid rats. Brain Res 791 (1998) 246-256