Biodistribution, cellular uptake and DNA-incorporation of the 2′-fluoro stabilized 5-iodo-2′-deoxyuridine analog 5-iodo-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)uracil (FIAU)

Quarterly Journal of Nuclear Medicine and Molecular Imaging

Volumn 52, Issue 3, 2008, Pages 305-316

  Morgenroth, A ^a   Deisenhofer, S ^a   Neininger, M ^a   Vogg, A T J ^a   Glatting, G ^a   Kull, T ^a   Reske, Sven N ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Biodistribution; Cellular uptake; DNA incorporation; FIAU

Indexed keywords

DNA; FIALURIDINE; IODINE 125; IODINE 131; KI 67 ANTIGEN; THYMIDINE KINASE 1; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; AUTORADIOGRAPHY; CELL LEVEL; CELL PROLIFERATION; CHEMICAL BOND; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DEHALOGENATION; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG DNA INTERACTION; DRUG HALF LIFE; DRUG STABILITY; DRUG STRUCTURE; DRUG UPTAKE; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; LEUKEMIA CELL; LYMPHOMA CELL; MALE; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; SMALL INTESTINE; SPLEEN CELL; STOMACH; TUMOR XENOGRAFT;

ANIMALS; ANTIVIRAL AGENTS; ARABINOFURANOSYLURACIL; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DNA; HL-60 CELLS; HUMANS; MICE; MICE, SCID; NEOPLASM TRANSPLANTATION; PHOSPHORYLATION; THYMIDINE KINASE; THYMIDINE PHOSPHORYLASE; TISSUE DISTRIBUTION;

EID: 48749105336     PISSN: 18244785     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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