Evaluation of 4′-[methyl-14C]thiothymidine for in vivo DNA synthesis imaging

Journal of Nuclear Medicine

Volumn 47, Issue 10, 2006, Pages 1717-1722

  Toyohara, Jun ^a   Kumata, Katsutoshi ^a   Fukushi, Kiyoshi ^a   Irie, Toshiaki ^a   Suzuki, Kazutoshi ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

4 thiothymidine; DNA synthesis; PET; Proliferation; Tumor

Indexed keywords

2 FLUORO 2' DEOXYCYTIDINE; 2 THYMIDINE C 14; 4 N METHYLIODOANTIPYRINE C 14; 4' METHYLTHIOTHYMIDINE C 14; 5 TRIMETHYLSTANNYL 4' THIO 2' DEOXYURIDINE; CARBON 14; DEOXYCYTIDINE; DEOXYURIDINE DERIVATIVE; METHYL IODIDE C 14; N,N DIMETHYLFORMAMIDE; PALLADIUM; RADIOPHARMACEUTICAL AGENT; THYMIDINE DERIVATIVE; TISSUE EXTRACT; UNCLASSIFIED DRUG; 4' THIOTHYMIDINE; 4'-THIOTHYMIDINE; CARBON; DIAGNOSTIC AGENT; DNA; DRUG DERIVATIVE; NUCLEIC ACID SYNTHESIS INHIBITOR; NUCLEOSIDE; THYMIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOWMETRY; CELL PROLIFERATION; CHEMICAL REACTION; CONTROLLED STUDY; DEGRADATION; DNA SYNTHESIS; DRUG DISTRIBUTION; DRUG SELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMAGING SYSTEM; INCUBATION TIME; METHYLATION; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; STILLE REACTION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CANCER TRANSPLANTATION; DRUG ANTAGONISM; HUMAN; TISSUE DISTRIBUTION; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; CARBON RADIOISOTOPES; CELL LINE, TUMOR; CELL PROLIFERATION; DNA; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; NUCLEIC ACID SYNTHESIS INHIBITORS; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; THIONUCLEOSIDES; THYMIDINE; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 35148869658     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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