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Volumn 21, Issue 8, 2008, Pages 925-936

Clinicopathological and molecular analysis of endometrial carcinoma associated with tamoxifen

Author keywords

catenin; Endometrial carcinoma; Estrogen; Pathogenesis; Tamoxifen

Indexed keywords

BETA CATENIN; K RAS PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TAMOXIFEN;

EID: 48749086763     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2008.49     Document Type: Article
Times cited : (18)

References (56)
  • 1
    • 0020660717 scopus 로고
    • Two pathogenetic types of endometrial carcinoma
    • Bokhman JV. Two pathogenetic types of endometrial carcinoma. Gynecol Oncol 1983;15:10-17.
    • (1983) Gynecol Oncol , vol.15 , pp. 10-17
    • Bokhman, J.V.1
  • 2
    • 1842506206 scopus 로고    scopus 로고
    • Molecular genetic pathways in various types of endometrial carcinoma: From a phenotypical to a molecular-based classification
    • Lax SF. Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification. Virchows Arch 2004;444:213-223.
    • (2004) Virchows Arch , vol.444 , pp. 213-223
    • Lax, S.F.1
  • 3
    • 0034950673 scopus 로고    scopus 로고
    • Molecular pathology of endometrial hyperplasia and carcinoma
    • Matias-Guiu X, Catasus L, Bussaglia E, et al. Molecular pathology of endometrial hyperplasia and carcinoma. Hum Pathol 2001;32:569-577.
    • (2001) Hum Pathol , vol.32 , pp. 569-577
    • Matias-Guiu, X.1    Catasus, L.2    Bussaglia, E.3
  • 4
    • 33745450851 scopus 로고    scopus 로고
    • The relationship between microsatellite instability and PTEN gene mutations in endometrial cancer
    • Bilbao C, Rodriguez G, Ramirez R, et al. The relationship between microsatellite instability and PTEN gene mutations in endometrial cancer. Int J Cancer 2006;119:563-570.
    • (2006) Int J Cancer , vol.119 , pp. 563-570
    • Bilbao, C.1    Rodriguez, G.2    Ramirez, R.3
  • 5
    • 0034616634 scopus 로고    scopus 로고
    • Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers
    • Mutter GL, Lin MC, Fitzgerald JT, et al. Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers. J Natl Cancer Inst 2000;92:924-930.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 924-930
    • Mutter, G.L.1    Lin, M.C.2    Fitzgerald, J.T.3
  • 6
    • 0032529234 scopus 로고    scopus 로고
    • Beta-catenin mutation in carcinoma of the uterine endometrium
    • Fukuchi T, Sakamoto M, Tsuda H, et al. Beta-catenin mutation in carcinoma of the uterine endometrium. Cancer Res 1998;58:3526-3528.
    • (1998) Cancer Res , vol.58 , pp. 3526-3528
    • Fukuchi, T.1    Sakamoto, M.2    Tsuda, H.3
  • 7
    • 0034651530 scopus 로고    scopus 로고
    • The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: Evidence of distinct molecular genetic pathways
    • Lax SF, Kendall B, Tashiro H, et al. The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways. Cancer 2000;88:814-824.
    • (2000) Cancer , vol.88 , pp. 814-824
    • Lax, S.F.1    Kendall, B.2    Tashiro, H.3
  • 8
    • 0035036476 scopus 로고    scopus 로고
    • Beta- and gamma-catenin expression in endometrial carcinoma. Relationship with clinicopathological features and microsatellite instability
    • Palacios J, Catasus L, Moreno-Bueno G, et al. Beta- and gamma-catenin expression in endometrial carcinoma. Relationship with clinicopathological features and microsatellite instability. Virchows Arch 2001;438:464-469.
    • (2001) Virchows Arch , vol.438 , pp. 464-469
    • Palacios, J.1    Catasus, L.2    Moreno-Bueno, G.3
  • 9
    • 0035153307 scopus 로고    scopus 로고
    • Betacatenin mutations and aberrant nuclear expression during endometrial tumorigenesis
    • Saegusa M, Hashimura M, Yoshida T, et al. Betacatenin mutations and aberrant nuclear expression during endometrial tumorigenesis. Br J Cancer 2001;84:209-217.
    • (2001) Br J Cancer , vol.84 , pp. 209-217
    • Saegusa, M.1    Hashimura, M.2    Yoshida, T.3
  • 10
    • 0028872141 scopus 로고
    • Mutations of the K-ras oncogene in carcinoma of the endometrium
    • Caduff RF, Johnston CM, Frank TS. Mutations of the K-ras oncogene in carcinoma of the endometrium. Am J Pathol 1995;146:182-188.
    • (1995) Am J Pathol , vol.146 , pp. 182-188
    • Caduff, R.F.1    Johnston, C.M.2    Frank, T.S.3
  • 11
    • 0025184539 scopus 로고
    • K-ras activation in neoplasms of the human female reproductive tract
    • Enomoto T, Inoue M, Perantoni AO, et al. K-ras activation in neoplasms of the human female reproductive tract. Cancer Res 1990;50:6139-6145.
    • (1990) Cancer Res , vol.50 , pp. 6139-6145
    • Enomoto, T.1    Inoue, M.2    Perantoni, A.O.3
  • 12
    • 0027157844 scopus 로고
    • Mutation of the K-ras protooncogene in human endometrial hyperplasia and carcinoma
    • Sasaki H, Nishii H, Takahashi H, et al. Mutation of the K-ras protooncogene in human endometrial hyperplasia and carcinoma. Cancer Res 1993;53:1906-1910.
    • (1993) Cancer Res , vol.53 , pp. 1906-1910
    • Sasaki, H.1    Nishii, H.2    Takahashi, H.3
  • 13
    • 33645819367 scopus 로고    scopus 로고
    • Clinicopathologic significance of defective DNA mismatch repair in endometrial carcinoma
    • Black D, Soslow RA, Levine DA, et al. Clinicopathologic significance of defective DNA mismatch repair in endometrial carcinoma. J Clin Oncol 2006;24:1745-1753.
    • (2006) J Clin Oncol , vol.24 , pp. 1745-1753
    • Black, D.1    Soslow, R.A.2    Levine, D.A.3
  • 15
    • 0023857383 scopus 로고
    • The dose-effect relationship between 'unopposed' oestrogens and endometrial mitotic rate: Its central role in explaining and predicting endometrial cancer risk
    • Key TJ, Pike MC. The dose-effect relationship between 'unopposed' oestrogens and endometrial mitotic rate: its central role in explaining and predicting endometrial cancer risk. Br J Cancer 1988;57:205-212.
    • (1988) Br J Cancer , vol.57 , pp. 205-212
    • Key, T.J.1    Pike, M.C.2
  • 16
    • 33750576103 scopus 로고    scopus 로고
    • Molecular and pathologic aspects of endometrial carcinogenesis
    • Hecht JL, Mutter GL. Molecular and pathologic aspects of endometrial carcinogenesis. J Clin Oncol 2006;24:4783-4791.
    • (2006) J Clin Oncol , vol.24 , pp. 4783-4791
    • Hecht, J.L.1    Mutter, G.L.2
  • 17
    • 0242288646 scopus 로고    scopus 로고
    • Regulation of PTEN (phosphatase and tensin homolog deleted on chromosome 10) expression by estradiol and progesterone in human endometrium
    • Guzeloglu-Kayisli O, Kayisli UA, Al-Rejjal R, et al. Regulation of PTEN (phosphatase and tensin homolog deleted on chromosome 10) expression by estradiol and progesterone in human endometrium. J Clin Endocrinol Metab 2003;88:5017-5026.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5017-5026
    • Guzeloglu-Kayisli, O.1    Kayisli, U.A.2    Al-Rejjal, R.3
  • 18
    • 4243175922 scopus 로고    scopus 로고
    • In vivo and in vitro regulation of Akt activation in human endometrial cells is estrogen dependent
    • Guzeloglu Kayisli O, Kayisli UA, Luleci G, et al. In vivo and in vitro regulation of Akt activation in human endometrial cells is estrogen dependent. Biol Reprod 2004;71:714-721.
    • (2004) Biol Reprod , vol.71 , pp. 714-721
    • Guzeloglu Kayisli, O.1    Kayisli, U.A.2    Luleci, G.3
  • 19
    • 0034456556 scopus 로고    scopus 로고
    • Changes in endometrial PTEN expression throughout the human menstrual cycle
    • Mutter GL, Lin MC, Fitzgerald JT, et al. Changes in endometrial PTEN expression throughout the human menstrual cycle. J Clin Endocrinol Metab 2000;85:2334-2338.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2334-2338
    • Mutter, G.L.1    Lin, M.C.2    Fitzgerald, J.T.3
  • 20
    • 0035687010 scopus 로고    scopus 로고
    • The effect of SERMs on the endometrium
    • Goldstein SR. The effect of SERMs on the endometrium. Ann N Y Acad Sci 2001;949:237-242.
    • (2001) Ann N Y Acad Sci , vol.949 , pp. 237-242
    • Goldstein, S.R.1
  • 21
    • 33745622906 scopus 로고    scopus 로고
    • Tamoxifen and uterine cancer
    • ACOG committee opinion
    • ACOG committee opinion. No. 336: Tamoxifen and uterine cancer. Obstet Gynecol 2006;107:1475-1478.
    • (2006) Obstet Gynecol , vol.107 , pp. 1475-1478
  • 22
    • 0033847413 scopus 로고    scopus 로고
    • Endometrial histopathology in 700 patients treated with tamoxifen for breast cancer
    • Deligdisch L, Kalir T, Cohen CJ, et al. Endometrial histopathology in 700 patients treated with tamoxifen for breast cancer. Gynecol Oncol 2000;78:181-186.
    • (2000) Gynecol Oncol , vol.78 , pp. 181-186
    • Deligdisch, L.1    Kalir, T.2    Cohen, C.J.3
  • 23
    • 0032537990 scopus 로고    scopus 로고
    • Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
    • Fisher B, Costantino JP, Wickerham DL, et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 1998;90:1371-1388.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1371-1388
    • Fisher, B.1    Costantino, J.P.2    Wickerham, D.L.3
  • 24
    • 0036067081 scopus 로고    scopus 로고
    • The effects of tamoxifen on proliferation and steroid receptor expression in postmenopausal endometrium
    • Mourits MJ, Ten Hoor KA, van der Zee AG, et al. The effects of tamoxifen on proliferation and steroid receptor expression in postmenopausal endometrium. J Clin Pathol 2002;55:514-519.
    • (2002) J Clin Pathol , vol.55 , pp. 514-519
    • Mourits, M.J.1    Ten Hoor, K.A.2    van der Zee, A.G.3
  • 25
    • 0030641037 scopus 로고    scopus 로고
    • Alterations in steroid hormone receptors in the tamoxifen-treated endometrium
    • Schwartz LB, Krey L, Demopoulos R, et al. Alterations in steroid hormone receptors in the tamoxifen-treated endometrium. Am J Obstet Gynecol 1997;176:129-137.
    • (1997) Am J Obstet Gynecol , vol.176 , pp. 129-137
    • Schwartz, L.B.1    Krey, L.2    Demopoulos, R.3
  • 26
    • 30144433414 scopus 로고    scopus 로고
    • Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis
    • Wu H, Chen Y, Liang J, et al. Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis. Nature 2005;438:981-987.
    • (2005) Nature , vol.438 , pp. 981-987
    • Wu, H.1    Chen, Y.2    Liang, J.3
  • 27
    • 33646371740 scopus 로고    scopus 로고
    • Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis
    • Shang Y. Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis. Nature Rev 2006;6:360-368.
    • (2006) Nature Rev , vol.6 , pp. 360-368
    • Shang, Y.1
  • 28
    • 34247378586 scopus 로고    scopus 로고
    • Hormones and cancer
    • Shang Y. Hormones and cancer. Cell Research 2007;17:277-279.
    • (2007) Cell Research , vol.17 , pp. 277-279
    • Shang, Y.1
  • 29
    • 0034092441 scopus 로고    scopus 로고
    • Lack of evidence for tamoxifen- and toremifene-DNA adducts in lymphocytes of treated patients
    • Bartsch H, Phillips DH, Nair J, et al. Lack of evidence for tamoxifen- and toremifene-DNA adducts in lymphocytes of treated patients. Carcinogenesis 2000;21:845-847.
    • (2000) Carcinogenesis , vol.21 , pp. 845-847
    • Bartsch, H.1    Phillips, D.H.2    Nair, J.3
  • 30
    • 0032930665 scopus 로고    scopus 로고
    • Lack of evidence from HPLC 32P-post-labelling for tamoxifen-DNA adducts in the human endometrium
    • Carmichael PL, Sardar S, Crooks N, et al. Lack of evidence from HPLC 32P-post-labelling for tamoxifen-DNA adducts in the human endometrium. Carcinogenesis 1999;20:339-342.
    • (1999) Carcinogenesis , vol.20 , pp. 339-342
    • Carmichael, P.L.1    Sardar, S.2    Crooks, N.3
  • 31
    • 0033065364 scopus 로고    scopus 로고
    • Comparison of the DNA adducts formed by tamoxifen and 4-hydroxytamoxifen in vivo
    • Beland FA, McDaniel LP, Marques MM. Comparison of the DNA adducts formed by tamoxifen and 4-hydroxytamoxifen in vivo. Carcinogenesis 1999;20:471-477.
    • (1999) Carcinogenesis , vol.20 , pp. 471-477
    • Beland, F.A.1    McDaniel, L.P.2    Marques, M.M.3
  • 32
    • 0141507957 scopus 로고    scopus 로고
    • Formation of tamoxifen-DNA adducts in multiple organs of adult female cynomolgus monkeys dosed with tamoxifen for 30 days
    • Schild LJ, Divi RL, Beland FA, et al. Formation of tamoxifen-DNA adducts in multiple organs of adult female cynomolgus monkeys dosed with tamoxifen for 30 days. Cancer Res 2003;63:5999-6003.
    • (2003) Cancer Res , vol.63 , pp. 5999-6003
    • Schild, L.J.1    Divi, R.L.2    Beland, F.A.3
  • 33
    • 0043092271 scopus 로고    scopus 로고
    • Identification of tamoxifen-DNA adducts in monkeys treated with tamoxifen
    • Shibutani S, Suzuki N, Laxmi YR, et al. Identification of tamoxifen-DNA adducts in monkeys treated with tamoxifen. Cancer Res 2003;63:4402-4406.
    • (2003) Cancer Res , vol.63 , pp. 4402-4406
    • Shibutani, S.1    Suzuki, N.2    Laxmi, Y.R.3
  • 34
    • 48749087370 scopus 로고    scopus 로고
    • Tavasolli F, Devilee P. WHO Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. IARC Press: Lyon, 2003, pp 221-228.
    • Tavasolli F, Devilee P. WHO Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. IARC Press: Lyon, 2003, pp 221-228.
  • 35
    • 18744368086 scopus 로고    scopus 로고
    • Abnormalities of the APC/beta-catenin pathway in endometrial cancer
    • Moreno-Bueno G, Hardisson D, Sanchez C, et al. Abnormalities of the APC/beta-catenin pathway in endometrial cancer. Oncogene 2002;21:7981-7990.
    • (2002) Oncogene , vol.21 , pp. 7981-7990
    • Moreno-Bueno, G.1    Hardisson, D.2    Sanchez, C.3
  • 36
    • 0030730905 scopus 로고    scopus 로고
    • Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors
    • Dahia PL, Marsh DJ, Zheng Z, et al. Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors. Cancer Res 1997;57:4710-4713.
    • (1997) Cancer Res , vol.57 , pp. 4710-4713
    • Dahia, P.L.1    Marsh, D.J.2    Zheng, Z.3
  • 37
    • 0033859582 scopus 로고    scopus 로고
    • Identification of tamoxifen-DNA adducts in the endometrium of women treated with tamoxifen
    • Shibutani S, Ravindernath A, Suzuki N, et al. Identification of tamoxifen-DNA adducts in the endometrium of women treated with tamoxifen. Carcinogenesis 2000;21:1461-1467.
    • (2000) Carcinogenesis , vol.21 , pp. 1461-1467
    • Shibutani, S.1    Ravindernath, A.2    Suzuki, N.3
  • 38
    • 0033135051 scopus 로고    scopus 로고
    • Mutagenic potential of alpha-(N2-deoxyguanosinyl) tamoxifen lesions, the major DNA adducts detected in endometrial tissues of patients treated with tamoxifen
    • Terashima I, Suzuki N, Shibutani S. Mutagenic potential of alpha-(N2-deoxyguanosinyl) tamoxifen lesions, the major DNA adducts detected in endometrial tissues of patients treated with tamoxifen. Cancer Res 1999;59:2091-2095.
    • (1999) Cancer Res , vol.59 , pp. 2091-2095
    • Terashima, I.1    Suzuki, N.2    Shibutani, S.3
  • 39
    • 9644307846 scopus 로고    scopus 로고
    • Canonical Wnt signaling is critical to estrogen-mediated uterine growth
    • Hou X, Tan Y, Li M, et al. Canonical Wnt signaling is critical to estrogen-mediated uterine growth. Mol Endocrin 2004;18:3035-3049.
    • (2004) Mol Endocrin , vol.18 , pp. 3035-3049
    • Hou, X.1    Tan, Y.2    Li, M.3
  • 40
    • 0043215023 scopus 로고    scopus 로고
    • Expression and regulation of WNT1 in human cancer: Up-regulation of WNT1 by beta-estradiol in MCF-7 cells
    • Katoh M. Expression and regulation of WNT1 in human cancer: up-regulation of WNT1 by beta-estradiol in MCF-7 cells. Int J Oncol 2003;22:209-212.
    • (2003) Int J Oncol , vol.22 , pp. 209-212
    • Katoh, M.1
  • 41
    • 0033518310 scopus 로고    scopus 로고
    • Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways
    • Easwaran V, Pishvaian M, Salimuddin, et al. Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways. Curr Biol 1999;9:1415-1418.
    • (1999) Curr Biol , vol.9 , pp. 1415-1418
    • Easwaran, V.1    Pishvaian, M.2    Salimuddin3
  • 42
    • 0034283030 scopus 로고    scopus 로고
    • Beta-catenin affects androgen receptor transcriptional activity and ligand specificity
    • Truica CI, Byers S, Gelmann EP. Beta-catenin affects androgen receptor transcriptional activity and ligand specificity. Cancer Res 2000;60:4709-4713.
    • (2000) Cancer Res , vol.60 , pp. 4709-4713
    • Truica, C.I.1    Byers, S.2    Gelmann, E.P.3
  • 43
    • 29144496090 scopus 로고    scopus 로고
    • Tamoxifen treatment for breast cancer enforces a distinct gene-expression profile on the human endometrium: An exploratory study
    • Gielen SC, Kuhne LC, Ewing PC, et al. Tamoxifen treatment for breast cancer enforces a distinct gene-expression profile on the human endometrium: an exploratory study. Endocr Relat Cancer 2005;12:1037-1049.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 1037-1049
    • Gielen, S.C.1    Kuhne, L.C.2    Ewing, P.C.3
  • 44
    • 25444494429 scopus 로고    scopus 로고
    • Distinct molecular alterations in complex endometrial hyperplasia (CEH) with and without immature squamous metaplasia (squamous morules)
    • Brachtel EF, Sanchez-Estevez C, Moreno-Bueno G, et al. Distinct molecular alterations in complex endometrial hyperplasia (CEH) with and without immature squamous metaplasia (squamous morules). Am J Surg Path 2005;29:1322-1329.
    • (2005) Am J Surg Path , vol.29 , pp. 1322-1329
    • Brachtel, E.F.1    Sanchez-Estevez, C.2    Moreno-Bueno, G.3
  • 45
    • 0032831839 scopus 로고    scopus 로고
    • Endometrial carcinoma in tamoxifen-treated breast cancer patient: Clinicopathological, immunohistochemical, and genetic analysis
    • Esteller M, Garcia A, Martinez-Palones JM, et al. Endometrial carcinoma in tamoxifen-treated breast cancer patient: clinicopathological, immunohistochemical, and genetic analysis. Int J Gynecol Pathol 1999;18:387-391.
    • (1999) Int J Gynecol Pathol , vol.18 , pp. 387-391
    • Esteller, M.1    Garcia, A.2    Martinez-Palones, J.M.3
  • 46
    • 0142212239 scopus 로고    scopus 로고
    • K-ras mutation in tamoxifen-related endometrial polyps
    • Hachisuga T, Miyakawa T, Tsujioka H, et al. K-ras mutation in tamoxifen-related endometrial polyps. Cancer 2003;98:1890-1897.
    • (2003) Cancer , vol.98 , pp. 1890-1897
    • Hachisuga, T.1    Miyakawa, T.2    Tsujioka, H.3
  • 47
    • 15044339820 scopus 로고    scopus 로고
    • Endometrial K-ras mutations in postmenopausal breast cancer patients treated with adjuvant tamoxifen or toremifene
    • Wallen M, Tomas E, Visakorpi T, et al. Endometrial K-ras mutations in postmenopausal breast cancer patients treated with adjuvant tamoxifen or toremifene. Cancer Chemother Pharmacol 2005;55:343-346.
    • (2005) Cancer Chemother Pharmacol , vol.55 , pp. 343-346
    • Wallen, M.1    Tomas, E.2    Visakorpi, T.3
  • 48
    • 0037192779 scopus 로고    scopus 로고
    • Contribution of estrogen receptor alpha to oncogenic K-Ras-mediated NIH3T3 cell transformation and its implication for escape from senescence by modulating the p53 pathway
    • Kato K, Horiuchi S, Takahashi A, et al. Contribution of estrogen receptor alpha to oncogenic K-Ras-mediated NIH3T3 cell transformation and its implication for escape from senescence by modulating the p53 pathway. J Biol Chem 2002;277:11217-11224.
    • (2002) J Biol Chem , vol.277 , pp. 11217-11224
    • Kato, K.1    Horiuchi, S.2    Takahashi, A.3
  • 49
    • 0031577696 scopus 로고    scopus 로고
    • Contribution of enhanced transcriptional activation by ER to [12Val] K-Ras mediated NIH3T3 cell transformation
    • Kato K, Ueoka Y, Kato K, et al. Contribution of enhanced transcriptional activation by ER to [12Val] K-Ras mediated NIH3T3 cell transformation. Oncogene 1997;15:3037-3046.
    • (1997) Oncogene , vol.15 , pp. 3037-3046
    • Kato, K.1    Ueoka, Y.2    Kato, K.3
  • 50
    • 10044294937 scopus 로고    scopus 로고
    • Molecular genetic characterization of tamoxifen-associated endometrial cancer
    • Prasad M, Wang H, Douglas W, et al. Molecular genetic characterization of tamoxifen-associated endometrial cancer. Gynecol Oncol 2005;96:25-31.
    • (2005) Gynecol Oncol , vol.96 , pp. 25-31
    • Prasad, M.1    Wang, H.2    Douglas, W.3
  • 51
    • 0036766031 scopus 로고    scopus 로고
    • PTEN expression in tamoxifen-associated endometrial cancers
    • Holtz D, Ramondetta LM, Burke TW, et al. PTEN expression in tamoxifen-associated endometrial cancers. Anticancer Res 2002;22:2945-2948.
    • (2002) Anticancer Res , vol.22 , pp. 2945-2948
    • Holtz, D.1    Ramondetta, L.M.2    Burke, T.W.3
  • 52
    • 0035361713 scopus 로고    scopus 로고
    • Molecular identification of latent precancers in histologically normal endometrium
    • Mutter GL, Ince TA, Baak JP, et al. Molecular identification of latent precancers in histologically normal endometrium. Cancer Res 2001;61:4311-4314.
    • (2001) Cancer Res , vol.61 , pp. 4311-4314
    • Mutter, G.L.1    Ince, T.A.2    Baak, J.P.3
  • 53
    • 33645742737 scopus 로고    scopus 로고
    • Akt-mediated phosphorylation and activation of estrogen receptor alpha is required for endometrial neoplastic transformation in Pten+/- mice
    • Vilgelm A, Lian Z, Wang H, et al. Akt-mediated phosphorylation and activation of estrogen receptor alpha is required for endometrial neoplastic transformation in Pten+/- mice. Cancer Res 2006;66:3375-3380.
    • (2006) Cancer Res , vol.66 , pp. 3375-3380
    • Vilgelm, A.1    Lian, Z.2    Wang, H.3
  • 54
    • 0035838584 scopus 로고    scopus 로고
    • Oestrogen receptors and microsatellite instability in colorectal carcinoma patients
    • Notarnicola M, Gristina R, Messa C, et al. Oestrogen receptors and microsatellite instability in colorectal carcinoma patients. Cancer Lett 2001;168:65-70.
    • (2001) Cancer Lett , vol.168 , pp. 65-70
    • Notarnicola, M.1    Gristina, R.2    Messa, C.3
  • 55
    • 0033774465 scopus 로고    scopus 로고
    • Microsatellite instability correlates with negative expression of estrogen and progesterone receptors in sporadic breast cancer
    • Caldes T, Perez-Segura P, Tosar A, et al. Microsatellite instability correlates with negative expression of estrogen and progesterone receptors in sporadic breast cancer. Teratog Carcinog Mutagen 2000;20:283-291.
    • (2000) Teratog Carcinog Mutagen , vol.20 , pp. 283-291
    • Caldes, T.1    Perez-Segura, P.2    Tosar, A.3
  • 56
    • 0343526384 scopus 로고    scopus 로고
    • Microsatellite alterations on human chromosome 11 in in situ and invasive breast cancer: A microdissection microsatellite analysis and correlation with p53, ER (estrogen receptor), and PR (progesterone receptor) protein immunoreactivity
    • Shen KL, Yang LS, Hsieh HF, et al. Microsatellite alterations on human chromosome 11 in in situ and invasive breast cancer: a microdissection microsatellite analysis and correlation with p53, ER (estrogen receptor), and PR (progesterone receptor) protein immunoreactivity. J Surg Oncol 2000;74:100-107.
    • (2000) J Surg Oncol , vol.74 , pp. 100-107
    • Shen, K.L.1    Yang, L.S.2    Hsieh, H.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.