-
1
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;266:66-71.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
-
2
-
-
33645003172
-
BRCA1: Cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution
-
Deng CX. BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution. Nucleic Acids Res 2006;34:1416-26.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 1416-1426
-
-
Deng, C.X.1
-
5
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev2003;3: 155-68.
-
Nat Rev2003;3
, pp. 155-168
-
-
Shiloh, Y.1
-
7
-
-
33644999937
-
-
Lieberman HB. Rad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity. J Cell Biochem 2006;97:690-7.
-
Lieberman HB. Rad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity. J Cell Biochem 2006;97:690-7.
-
-
-
-
8
-
-
4043133233
-
The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase h and increases its DNA substrate utilisation efficiency: Implications for DNA repair
-
Toueille M, El-Andaloussi N, Frouin I, et al. The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase h and increases its DNA substrate utilisation efficiency: implications for DNA repair. Nucleic Acids Res 2004;32:3316-24.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 3316-3324
-
-
Toueille, M.1
El-Andaloussi, N.2
Frouin, I.3
-
9
-
-
10844262639
-
Accumulation of hRad9 protein in the nuclei of nonsmall cell lung carcinoma cells
-
Maniwa Y, Yoshimura M, Bermudez VP, et al. Accumulation of hRad9 protein in the nuclei of nonsmall cell lung carcinoma cells. Cancer 2005;103:126-32.
-
(2005)
Cancer
, vol.103
, pp. 126-132
-
-
Maniwa, Y.1
Yoshimura, M.2
Bermudez, V.P.3
-
10
-
-
25444478299
-
The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer
-
Cheng CK, Chow LW, Loo WT, Chan TK, Chan V. The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer. Cancer Res 2005;65:8646-54.
-
(2005)
Cancer Res
, vol.65
, pp. 8646-8654
-
-
Cheng, C.K.1
Chow, L.W.2
Loo, W.T.3
Chan, T.K.4
Chan, V.5
-
11
-
-
33644511711
-
His239Arg SNP of HRAD9 is associated with lung adenocarcinoma
-
Maniwa Y, Yoshimura M, Bermudez VP, et al. His239Arg SNP of HRAD9 is associated with lung adenocarcinoma. Cancer 2006;106:1117-22.
-
(2006)
Cancer
, vol.106
, pp. 1117-1122
-
-
Maniwa, Y.1
Yoshimura, M.2
Bermudez, V.P.3
-
12
-
-
1342282903
-
Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells
-
Wang L, Hsu CL, Ni J, et al. Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells. Mol Cell Biol 2004;24:2202-13.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2202-2213
-
-
Wang, L.1
Hsu, C.L.2
Ni, J.3
-
13
-
-
40449115915
-
Rad9 has a functional role in human prostate carcinogenesis
-
Zhu A, Zhang X, Lieberman HB. Rad9 has a functional role in human prostate carcinogenesis. Cancer Res 2008;68:1267-74.
-
(2008)
Cancer Res
, vol.68
, pp. 1267-1274
-
-
Zhu, A.1
Zhang, X.2
Lieberman, H.B.3
-
14
-
-
13444272954
-
Combined haploinsufficiency for ATM and RAD9 as a factor in cell transformation, apoptosis, and DNA lesion repair dynamics
-
SmilenovLB, Lieberman HB, Mitchell SA, Baker RA, Hopkins KM, Hall EJ. Combined haploinsufficiency for ATM and RAD9 as a factor in cell transformation, apoptosis, and DNA lesion repair dynamics. Cancer Res 2005;65:933-8.
-
(2005)
Cancer Res
, vol.65
, pp. 933-938
-
-
Smilenov, L.B.1
Lieberman, H.B.2
Mitchell, S.A.3
Baker, R.A.4
Hopkins, K.M.5
Hall, E.J.6
-
15
-
-
3543028030
-
Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality
-
Hopkins KM, Auerbach W, Wang XY, et al. Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality. Mol Cell Biol 2004;24:7235-48.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7235-7248
-
-
Hopkins, K.M.1
Auerbach, W.2
Wang, X.Y.3
-
16
-
-
0038823886
-
Establishment of keratinocyte-specific Cre recombinase transgenic mice]
-
Mao CM, Yang X, Cheng X, Lu YX, Zhou J, Huang CF. [Establishment of keratinocyte-specific Cre recombinase transgenic mice]. Yi Chuan Xue Bao 2003;30:407-13.
-
(2003)
Yi Chuan Xue Bao
, vol.30
, pp. 407-413
-
-
Mao, C.M.1
Yang, X.2
Cheng, X.3
Lu, Y.X.4
Zhou, J.5
Huang, C.F.6
-
17
-
-
0036724625
-
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner
-
Hirao A, Cheung A, Duncan G, et al. Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol Cell Biol 2002;22:6521-32.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6521-6532
-
-
Hirao, A.1
Cheung, A.2
Duncan, G.3
-
18
-
-
25444473619
-
Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors
-
Yang L, Mao C, Teng Y, et al. Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors. Cancer Res 2005;65:8671-8.
-
(2005)
Cancer Res
, vol.65
, pp. 8671-8678
-
-
Yang, L.1
Mao, C.2
Teng, Y.3
-
19
-
-
0037309972
-
Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation
-
Suzuki A, Itami S, Ohishi M, et al. Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation. Cancer Res 2003;63:674-81.
-
(2003)
Cancer Res
, vol.63
, pp. 674-681
-
-
Suzuki, A.1
Itami, S.2
Ohishi, M.3
-
21
-
-
77952626804
-
Analysis of the mammalian cell cycle by flow cytometry
-
Lieberman HB, editor, Totowa NJ, Humana Press;
-
Hang HYFM. Analysis of the mammalian cell cycle by flow cytometry. In: Lieberman HB, editor. Cell cycle checkpoint control protocols. Totowa (NJ): Humana Press; 2004.
-
(2004)
Cell cycle checkpoint control protocols
-
-
Hang, H.Y.F.M.1
-
22
-
-
54749088130
-
-
SAS Institute Inc. SAS/STAT®9.1 User's Guide: Cary (NC): SAS Institute Inc.; 2004.
-
SAS Institute Inc. SAS/STAT®9.1 User's Guide: Cary (NC): SAS Institute Inc.; 2004.
-
-
-
-
24
-
-
0041335228
-
The Design of Animal Experiments. Reducing the use of animals in research through better experimental design
-
London: The Royal Society of Medicine Press Ltd;
-
Michael FW, Festing PO, Das RG, Borja MC, Berdoy M. The Design of Animal Experiments. Reducing the use of animals in research through better experimental design. Laboratory Animal Handbooks NO. 14. London: The Royal Society of Medicine Press Ltd; 2002.
-
(2002)
Laboratory Animal Handbooks
, Issue.14
-
-
Michael, F.W.1
Festing, P.O.2
Das, R.G.3
Borja, M.C.4
Berdoy, M.5
-
25
-
-
0022527161
-
Carcinogen-specific mutation and amplification of Haras during mouse skin carcinogenesis
-
Quintanilla M, Brown K, Ramsden M, Balmain A. Carcinogen-specific mutation and amplification of Haras during mouse skin carcinogenesis. Nature 1986;322:78-80.
-
(1986)
Nature
, vol.322
, pp. 78-80
-
-
Quintanilla, M.1
Brown, K.2
Ramsden, M.3
Balmain, A.4
-
26
-
-
0025865243
-
Oncogene involvement in tumor regression: H-ras activation in the rabbit keratoacanthoma model
-
Corominas M, Leon J, Kamino H, Cruz-Alvarez M, Novick SC, Pellicer A. Oncogene involvement in tumor regression: H-ras activation in the rabbit keratoacanthoma model. Oncogene 1991;6:645-51.
-
(1991)
Oncogene
, vol.6
, pp. 645-651
-
-
Corominas, M.1
Leon, J.2
Kamino, H.3
Cruz-Alvarez, M.4
Novick, S.C.5
Pellicer, A.6
-
27
-
-
0022558830
-
Gross and microscopic lesions in the female SENCAR mouse skin and lung in tumor initiation and promotion studies
-
Knutsen GL, Kovatch RM, Robinson M. Gross and microscopic lesions in the female SENCAR mouse skin and lung in tumor initiation and promotion studies. Environ Health Perspect 1986;68:91-104.
-
(1986)
Environ Health Perspect
, vol.68
, pp. 91-104
-
-
Knutsen, G.L.1
Kovatch, R.M.2
Robinson, M.3
-
28
-
-
0020557197
-
Oxygen tension regulates the expression of angiogenesis factor by macrophages
-
Knighton DR, Hunt TK, Scheuenstuhl H, Halliday BJ, Werb Z, Banda MJ. Oxygen tension regulates the expression of angiogenesis factor by macrophages. Science 1983;221:1283-5.
-
(1983)
Science
, vol.221
, pp. 1283-1285
-
-
Knighton, D.R.1
Hunt, T.K.2
Scheuenstuhl, H.3
Halliday, B.J.4
Werb, Z.5
Banda, M.J.6
-
29
-
-
0029051426
-
Oxidative DNA damage and senescence of human diploid fibroblast cells
-
Chen Q, Fischer A, Reagan JD, Yan LJ, Ames BN. Oxidative DNA damage and senescence of human diploid fibroblast cells. Proc Natl Acad Sci U S A 1995;92:4337-41.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 4337-4341
-
-
Chen, Q.1
Fischer, A.2
Reagan, J.D.3
Yan, L.J.4
Ames, B.N.5
-
30
-
-
0028915601
-
The effect of low oxygen tension on the in vitro -replicative life span of human diploid fibroblast cells and their transformed derivatives
-
Saito H, Hammond AT, Moses RE. The effect of low oxygen tension on the in vitro -replicative life span of human diploid fibroblast cells and their transformed derivatives. Exp Cell Res 1995;217:272-9.
-
(1995)
Exp Cell Res
, vol.217
, pp. 272-279
-
-
Saito, H.1
Hammond, A.T.2
Moses, R.E.3
-
31
-
-
0031815389
-
Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols
-
Yang GY, Liao J, Kim K, Yurkow EJ, Yang CS. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis 1998;19:611-6.
-
(1998)
Carcinogenesis
, vol.19
, pp. 611-616
-
-
Yang, G.Y.1
Liao, J.2
Kim, K.3
Yurkow, E.J.4
Yang, C.S.5
-
32
-
-
0031444312
-
Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells
-
Ahmad N, Feyes DK, Nieminen AL, Agarwal R, Mukhtar H. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J Natl Cancer Inst 1997;89:1881-6.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1881-1886
-
-
Ahmad, N.1
Feyes, D.K.2
Nieminen, A.L.3
Agarwal, R.4
Mukhtar, H.5
-
33
-
-
33745809541
-
Extent of constitutive histone H2AX phosphorylation on Ser-139 varies in cells with different TP53 status
-
Tanaka T, Kurose A, Huang X, Traganos F, Dai W, Darzynkiewicz Z. Extent of constitutive histone H2AX phosphorylation on Ser-139 varies in cells with different TP53 status. Cell Prolif 2006;39:313-23.
-
(2006)
Cell Prolif
, vol.39
, pp. 313-323
-
-
Tanaka, T.1
Kurose, A.2
Huang, X.3
Traganos, F.4
Dai, W.5
Darzynkiewicz, Z.6
-
34
-
-
0038309713
-
Comparison of comet assay, electron microscopy, and flow cytometry for detection of apoptosis
-
Yasuhara S, Zhu Y, Matsui T, et al. Comparison of comet assay, electron microscopy, and flow cytometry for detection of apoptosis. J Histochem Cytochem 2003;51:873-85.
-
(2003)
J Histochem Cytochem
, vol.51
, pp. 873-885
-
-
Yasuhara, S.1
Zhu, Y.2
Matsui, T.3
-
35
-
-
27444437080
-
Differential impact of mouse Rad9 deletion on ionizing radiation-induced bystander effects
-
Zhu A, Zhou H, Leloup C, et al. Differential impact of mouse Rad9 deletion on ionizing radiation-induced bystander effects. Radiat Res 2005;164:655-61.
-
(2005)
Radiat Res
, vol.164
, pp. 655-661
-
-
Zhu, A.1
Zhou, H.2
Leloup, C.3
-
36
-
-
34250705797
-
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
-
Delacroix S, Wagner JM, Kobayashi M, Yamamoto K, Karnitz LM. The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1. Genes Dev 2007;21:1472-7.
-
(2007)
Genes Dev
, vol.21
, pp. 1472-1477
-
-
Delacroix, S.1
Wagner, J.M.2
Kobayashi, M.3
Yamamoto, K.4
Karnitz, L.M.5
-
37
-
-
22144468371
-
The human checkpoint sensor and alternative DNA clamp Rad9-1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery
-
Smirnova E, Toueille M, Markkanen E, Hubscher U. The human checkpoint sensor and alternative DNA clamp Rad9-1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery. Biochem J 2005;389:13-7.
-
(2005)
Biochem J
, vol.389
, pp. 13-17
-
-
Smirnova, E.1
Toueille, M.2
Markkanen, E.3
Hubscher, U.4
-
38
-
-
33644555829
-
Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair
-
Pandita RK, Sharma GG, Laszlo A, et al. Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair. Mol Cell Biol 2006;26:1850-64.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 1850-1864
-
-
Pandita, R.K.1
Sharma, G.G.2
Laszlo, A.3
-
39
-
-
33745744063
-
The Rad9 protein enhances survival and promotes DNA repair following exposure to ionizing radiation
-
Brandt PD, Helt CE, Keng PC, Bambara RA. The Rad9 protein enhances survival and promotes DNA repair following exposure to ionizing radiation. Biochem Biophys Res Commun 2006;347:232-7.
-
(2006)
Biochem Biophys Res Commun
, vol.347
, pp. 232-237
-
-
Brandt, P.D.1
Helt, C.E.2
Keng, P.C.3
Bambara, R.A.4
-
40
-
-
34250361079
-
The human checkpoint sensor Rad9-1-Hus1 interacts with and stimulates NEIL1 glycosylase
-
Guan X, Bai H, Shi G, et al. The human checkpoint sensor Rad9-1-Hus1 interacts with and stimulates NEIL1 glycosylase. Nucleic Acids Res 2007;35:2463-72.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 2463-2472
-
-
Guan, X.1
Bai, H.2
Shi, G.3
-
41
-
-
33746383493
-
Mechanism of stimulation of human DNA ligase I by the Rad9-1-Hus1 checkpoint complex
-
Wang W, Lindsey-Boltz LA, Sancar A, Bambara RA. Mechanism of stimulation of human DNA ligase I by the Rad9-1-Hus1 checkpoint complex. J Biol Chem 2006;281:20865-72.
-
(2006)
J Biol Chem
, vol.281
, pp. 20865-20872
-
-
Wang, W.1
Lindsey-Boltz, L.A.2
Sancar, A.3
Bambara, R.A.4
-
42
-
-
10044272942
-
The human Rad9-1-Hus1 checkpoint complex stimulates flap endonuclease 1
-
Wang W, Brandt P, Rossi ML, et al. The human Rad9-1-Hus1 checkpoint complex stimulates flap endonuclease 1. Proc Natl Acad Sci U S A 2004;101:16762-7.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 16762-16767
-
-
Wang, W.1
Brandt, P.2
Rossi, M.L.3
-
43
-
-
33751100898
-
Physical and functional interactions between MutY glycosylase homologue (MYH) and checkpoint proteins Rad9-1-Hus1
-
Shi G, Chang DY, Cheng CC, Guan X, Venclovas C, Lu AL. Physical and functional interactions between MutY glycosylase homologue (MYH) and checkpoint proteins Rad9-1-Hus1. Biochem J 2006;400:53-62.
-
(2006)
Biochem J
, vol.400
, pp. 53-62
-
-
Shi, G.1
Chang, D.Y.2
Cheng, C.C.3
Guan, X.4
Venclovas, C.5
Lu, A.L.6
-
44
-
-
0035844130
-
ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation
-
Chen MJ, Lin YT, Lieberman HB, Chen G, Lee EY. ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation. J Biol Chem 2001;276:16580-6.
-
(2001)
J Biol Chem
, vol.276
, pp. 16580-16586
-
-
Chen, M.J.1
Lin, Y.T.2
Lieberman, H.B.3
Chen, G.4
Lee, E.Y.5
-
45
-
-
1942424060
-
Critical role for chicken Rad17 and Rad9 in the cellular response to DNA damage and stalled DNA replication
-
Kobayashi M, Hirano A, Kumano T, et al. Critical role for chicken Rad17 and Rad9 in the cellular response to DNA damage and stalled DNA replication. Genes Cells 2004;9:291-303.
-
(2004)
Genes Cells
, vol.9
, pp. 291-303
-
-
Kobayashi, M.1
Hirano, A.2
Kumano, T.3
-
46
-
-
15944424299
-
Human Rad9 is required for the activation of S-phase checkpoint and the maintenance of chromosomal stability
-
Dang T, Bao S, Wang XF. Human Rad9 is required for the activation of S-phase checkpoint and the maintenance of chromosomal stability. Genes Cells 2005;10:287-95.
-
(2005)
Genes Cells
, vol.10
, pp. 287-295
-
-
Dang, T.1
Bao, S.2
Wang, X.F.3
-
47
-
-
0036241988
-
c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage
-
Yoshida K, Komatsu K, Wang HG, Kufe D. c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage. Mol Cell Biol 2002;22:3292-300.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3292-3300
-
-
Yoshida, K.1
Komatsu, K.2
Wang, H.G.3
Kufe, D.4
-
48
-
-
0038237433
-
Protein kinase Cδ is responsible for constitutive and DNA damage-induced phosphorylation of Rad9
-
Yoshida K, Wang HG, Miki Y, Kufe D. Protein kinase Cδ is responsible for constitutive and DNA damage-induced phosphorylation of Rad9. EMBO J 2003;22:1431-41.
-
(2003)
EMBO J
, vol.22
, pp. 1431-1441
-
-
Yoshida, K.1
Wang, H.G.2
Miki, Y.3
Kufe, D.4
-
49
-
-
0033794570
-
Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis
-
Komatsu K, Miyashita T, Hang H, et al. Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis. Nat Cell Biol 2000;2:1-6.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 1-6
-
-
Komatsu, K.1
Miyashita, T.2
Hang, H.3
-
50
-
-
2942691396
-
Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21
-
Yin Y, Zhu A, Jin YJ, et al. Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21. Proc Natl Acad Sci U S A 2004;101:8864-9.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8864-8869
-
-
Yin, Y.1
Zhu, A.2
Jin, Y.J.3
|