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Volumn 68, Issue 14, 2008, Pages 5552-5561

Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE; EPIGALLOCATECHIN GALLATE; PROTEIN P21; PROTEIN P53; PROTEIN RAD9; 7,12 DIMETHYLBENZ[A]ANTHRACENE; CARCINOGEN; CELL CYCLE PROTEIN; MUTAGENIC AGENT;

EID: 48649106833     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-5670     Document Type: Article
Times cited : (30)

References (50)
  • 1
    • 0028113345 scopus 로고
    • A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
    • Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;266:66-71.
    • (1994) Science , vol.266 , pp. 66-71
    • Miki, Y.1    Swensen, J.2    Shattuck-Eidens, D.3
  • 2
    • 33645003172 scopus 로고    scopus 로고
    • BRCA1: Cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution
    • Deng CX. BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution. Nucleic Acids Res 2006;34:1416-26.
    • (2006) Nucleic Acids Res , vol.34 , pp. 1416-1426
    • Deng, C.X.1
  • 3
  • 5
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev2003;3: 155-68.
    • Nat Rev2003;3 , pp. 155-168
    • Shiloh, Y.1
  • 7
    • 33644999937 scopus 로고    scopus 로고
    • Lieberman HB. Rad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity. J Cell Biochem 2006;97:690-7.
    • Lieberman HB. Rad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity. J Cell Biochem 2006;97:690-7.
  • 8
    • 4043133233 scopus 로고    scopus 로고
    • The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase h and increases its DNA substrate utilisation efficiency: Implications for DNA repair
    • Toueille M, El-Andaloussi N, Frouin I, et al. The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase h and increases its DNA substrate utilisation efficiency: implications for DNA repair. Nucleic Acids Res 2004;32:3316-24.
    • (2004) Nucleic Acids Res , vol.32 , pp. 3316-3324
    • Toueille, M.1    El-Andaloussi, N.2    Frouin, I.3
  • 9
    • 10844262639 scopus 로고    scopus 로고
    • Accumulation of hRad9 protein in the nuclei of nonsmall cell lung carcinoma cells
    • Maniwa Y, Yoshimura M, Bermudez VP, et al. Accumulation of hRad9 protein in the nuclei of nonsmall cell lung carcinoma cells. Cancer 2005;103:126-32.
    • (2005) Cancer , vol.103 , pp. 126-132
    • Maniwa, Y.1    Yoshimura, M.2    Bermudez, V.P.3
  • 10
    • 25444478299 scopus 로고    scopus 로고
    • The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer
    • Cheng CK, Chow LW, Loo WT, Chan TK, Chan V. The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer. Cancer Res 2005;65:8646-54.
    • (2005) Cancer Res , vol.65 , pp. 8646-8654
    • Cheng, C.K.1    Chow, L.W.2    Loo, W.T.3    Chan, T.K.4    Chan, V.5
  • 11
    • 33644511711 scopus 로고    scopus 로고
    • His239Arg SNP of HRAD9 is associated with lung adenocarcinoma
    • Maniwa Y, Yoshimura M, Bermudez VP, et al. His239Arg SNP of HRAD9 is associated with lung adenocarcinoma. Cancer 2006;106:1117-22.
    • (2006) Cancer , vol.106 , pp. 1117-1122
    • Maniwa, Y.1    Yoshimura, M.2    Bermudez, V.P.3
  • 12
    • 1342282903 scopus 로고    scopus 로고
    • Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells
    • Wang L, Hsu CL, Ni J, et al. Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells. Mol Cell Biol 2004;24:2202-13.
    • (2004) Mol Cell Biol , vol.24 , pp. 2202-2213
    • Wang, L.1    Hsu, C.L.2    Ni, J.3
  • 13
    • 40449115915 scopus 로고    scopus 로고
    • Rad9 has a functional role in human prostate carcinogenesis
    • Zhu A, Zhang X, Lieberman HB. Rad9 has a functional role in human prostate carcinogenesis. Cancer Res 2008;68:1267-74.
    • (2008) Cancer Res , vol.68 , pp. 1267-1274
    • Zhu, A.1    Zhang, X.2    Lieberman, H.B.3
  • 14
    • 13444272954 scopus 로고    scopus 로고
    • Combined haploinsufficiency for ATM and RAD9 as a factor in cell transformation, apoptosis, and DNA lesion repair dynamics
    • SmilenovLB, Lieberman HB, Mitchell SA, Baker RA, Hopkins KM, Hall EJ. Combined haploinsufficiency for ATM and RAD9 as a factor in cell transformation, apoptosis, and DNA lesion repair dynamics. Cancer Res 2005;65:933-8.
    • (2005) Cancer Res , vol.65 , pp. 933-938
    • Smilenov, L.B.1    Lieberman, H.B.2    Mitchell, S.A.3    Baker, R.A.4    Hopkins, K.M.5    Hall, E.J.6
  • 15
    • 3543028030 scopus 로고    scopus 로고
    • Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality
    • Hopkins KM, Auerbach W, Wang XY, et al. Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality. Mol Cell Biol 2004;24:7235-48.
    • (2004) Mol Cell Biol , vol.24 , pp. 7235-7248
    • Hopkins, K.M.1    Auerbach, W.2    Wang, X.Y.3
  • 16
  • 17
    • 0036724625 scopus 로고    scopus 로고
    • Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner
    • Hirao A, Cheung A, Duncan G, et al. Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol Cell Biol 2002;22:6521-32.
    • (2002) Mol Cell Biol , vol.22 , pp. 6521-6532
    • Hirao, A.1    Cheung, A.2    Duncan, G.3
  • 18
    • 25444473619 scopus 로고    scopus 로고
    • Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors
    • Yang L, Mao C, Teng Y, et al. Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors. Cancer Res 2005;65:8671-8.
    • (2005) Cancer Res , vol.65 , pp. 8671-8678
    • Yang, L.1    Mao, C.2    Teng, Y.3
  • 19
    • 0037309972 scopus 로고    scopus 로고
    • Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation
    • Suzuki A, Itami S, Ohishi M, et al. Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation. Cancer Res 2003;63:674-81.
    • (2003) Cancer Res , vol.63 , pp. 674-681
    • Suzuki, A.1    Itami, S.2    Ohishi, M.3
  • 21
    • 77952626804 scopus 로고    scopus 로고
    • Analysis of the mammalian cell cycle by flow cytometry
    • Lieberman HB, editor, Totowa NJ, Humana Press;
    • Hang HYFM. Analysis of the mammalian cell cycle by flow cytometry. In: Lieberman HB, editor. Cell cycle checkpoint control protocols. Totowa (NJ): Humana Press; 2004.
    • (2004) Cell cycle checkpoint control protocols
    • Hang, H.Y.F.M.1
  • 22
    • 54749088130 scopus 로고    scopus 로고
    • SAS Institute Inc. SAS/STAT®9.1 User's Guide: Cary (NC): SAS Institute Inc.; 2004.
    • SAS Institute Inc. SAS/STAT®9.1 User's Guide: Cary (NC): SAS Institute Inc.; 2004.
  • 24
    • 0041335228 scopus 로고    scopus 로고
    • The Design of Animal Experiments. Reducing the use of animals in research through better experimental design
    • London: The Royal Society of Medicine Press Ltd;
    • Michael FW, Festing PO, Das RG, Borja MC, Berdoy M. The Design of Animal Experiments. Reducing the use of animals in research through better experimental design. Laboratory Animal Handbooks NO. 14. London: The Royal Society of Medicine Press Ltd; 2002.
    • (2002) Laboratory Animal Handbooks , Issue.14
    • Michael, F.W.1    Festing, P.O.2    Das, R.G.3    Borja, M.C.4    Berdoy, M.5
  • 25
    • 0022527161 scopus 로고
    • Carcinogen-specific mutation and amplification of Haras during mouse skin carcinogenesis
    • Quintanilla M, Brown K, Ramsden M, Balmain A. Carcinogen-specific mutation and amplification of Haras during mouse skin carcinogenesis. Nature 1986;322:78-80.
    • (1986) Nature , vol.322 , pp. 78-80
    • Quintanilla, M.1    Brown, K.2    Ramsden, M.3    Balmain, A.4
  • 26
    • 0025865243 scopus 로고
    • Oncogene involvement in tumor regression: H-ras activation in the rabbit keratoacanthoma model
    • Corominas M, Leon J, Kamino H, Cruz-Alvarez M, Novick SC, Pellicer A. Oncogene involvement in tumor regression: H-ras activation in the rabbit keratoacanthoma model. Oncogene 1991;6:645-51.
    • (1991) Oncogene , vol.6 , pp. 645-651
    • Corominas, M.1    Leon, J.2    Kamino, H.3    Cruz-Alvarez, M.4    Novick, S.C.5    Pellicer, A.6
  • 27
    • 0022558830 scopus 로고
    • Gross and microscopic lesions in the female SENCAR mouse skin and lung in tumor initiation and promotion studies
    • Knutsen GL, Kovatch RM, Robinson M. Gross and microscopic lesions in the female SENCAR mouse skin and lung in tumor initiation and promotion studies. Environ Health Perspect 1986;68:91-104.
    • (1986) Environ Health Perspect , vol.68 , pp. 91-104
    • Knutsen, G.L.1    Kovatch, R.M.2    Robinson, M.3
  • 30
    • 0028915601 scopus 로고
    • The effect of low oxygen tension on the in vitro -replicative life span of human diploid fibroblast cells and their transformed derivatives
    • Saito H, Hammond AT, Moses RE. The effect of low oxygen tension on the in vitro -replicative life span of human diploid fibroblast cells and their transformed derivatives. Exp Cell Res 1995;217:272-9.
    • (1995) Exp Cell Res , vol.217 , pp. 272-279
    • Saito, H.1    Hammond, A.T.2    Moses, R.E.3
  • 31
    • 0031815389 scopus 로고    scopus 로고
    • Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols
    • Yang GY, Liao J, Kim K, Yurkow EJ, Yang CS. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis 1998;19:611-6.
    • (1998) Carcinogenesis , vol.19 , pp. 611-616
    • Yang, G.Y.1    Liao, J.2    Kim, K.3    Yurkow, E.J.4    Yang, C.S.5
  • 32
    • 0031444312 scopus 로고    scopus 로고
    • Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells
    • Ahmad N, Feyes DK, Nieminen AL, Agarwal R, Mukhtar H. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J Natl Cancer Inst 1997;89:1881-6.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1881-1886
    • Ahmad, N.1    Feyes, D.K.2    Nieminen, A.L.3    Agarwal, R.4    Mukhtar, H.5
  • 33
    • 33745809541 scopus 로고    scopus 로고
    • Extent of constitutive histone H2AX phosphorylation on Ser-139 varies in cells with different TP53 status
    • Tanaka T, Kurose A, Huang X, Traganos F, Dai W, Darzynkiewicz Z. Extent of constitutive histone H2AX phosphorylation on Ser-139 varies in cells with different TP53 status. Cell Prolif 2006;39:313-23.
    • (2006) Cell Prolif , vol.39 , pp. 313-323
    • Tanaka, T.1    Kurose, A.2    Huang, X.3    Traganos, F.4    Dai, W.5    Darzynkiewicz, Z.6
  • 34
    • 0038309713 scopus 로고    scopus 로고
    • Comparison of comet assay, electron microscopy, and flow cytometry for detection of apoptosis
    • Yasuhara S, Zhu Y, Matsui T, et al. Comparison of comet assay, electron microscopy, and flow cytometry for detection of apoptosis. J Histochem Cytochem 2003;51:873-85.
    • (2003) J Histochem Cytochem , vol.51 , pp. 873-885
    • Yasuhara, S.1    Zhu, Y.2    Matsui, T.3
  • 35
    • 27444437080 scopus 로고    scopus 로고
    • Differential impact of mouse Rad9 deletion on ionizing radiation-induced bystander effects
    • Zhu A, Zhou H, Leloup C, et al. Differential impact of mouse Rad9 deletion on ionizing radiation-induced bystander effects. Radiat Res 2005;164:655-61.
    • (2005) Radiat Res , vol.164 , pp. 655-661
    • Zhu, A.1    Zhou, H.2    Leloup, C.3
  • 36
  • 37
    • 22144468371 scopus 로고    scopus 로고
    • The human checkpoint sensor and alternative DNA clamp Rad9-1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery
    • Smirnova E, Toueille M, Markkanen E, Hubscher U. The human checkpoint sensor and alternative DNA clamp Rad9-1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery. Biochem J 2005;389:13-7.
    • (2005) Biochem J , vol.389 , pp. 13-17
    • Smirnova, E.1    Toueille, M.2    Markkanen, E.3    Hubscher, U.4
  • 38
    • 33644555829 scopus 로고    scopus 로고
    • Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair
    • Pandita RK, Sharma GG, Laszlo A, et al. Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair. Mol Cell Biol 2006;26:1850-64.
    • (2006) Mol Cell Biol , vol.26 , pp. 1850-1864
    • Pandita, R.K.1    Sharma, G.G.2    Laszlo, A.3
  • 39
    • 33745744063 scopus 로고    scopus 로고
    • The Rad9 protein enhances survival and promotes DNA repair following exposure to ionizing radiation
    • Brandt PD, Helt CE, Keng PC, Bambara RA. The Rad9 protein enhances survival and promotes DNA repair following exposure to ionizing radiation. Biochem Biophys Res Commun 2006;347:232-7.
    • (2006) Biochem Biophys Res Commun , vol.347 , pp. 232-237
    • Brandt, P.D.1    Helt, C.E.2    Keng, P.C.3    Bambara, R.A.4
  • 40
    • 34250361079 scopus 로고    scopus 로고
    • The human checkpoint sensor Rad9-1-Hus1 interacts with and stimulates NEIL1 glycosylase
    • Guan X, Bai H, Shi G, et al. The human checkpoint sensor Rad9-1-Hus1 interacts with and stimulates NEIL1 glycosylase. Nucleic Acids Res 2007;35:2463-72.
    • (2007) Nucleic Acids Res , vol.35 , pp. 2463-2472
    • Guan, X.1    Bai, H.2    Shi, G.3
  • 41
    • 33746383493 scopus 로고    scopus 로고
    • Mechanism of stimulation of human DNA ligase I by the Rad9-1-Hus1 checkpoint complex
    • Wang W, Lindsey-Boltz LA, Sancar A, Bambara RA. Mechanism of stimulation of human DNA ligase I by the Rad9-1-Hus1 checkpoint complex. J Biol Chem 2006;281:20865-72.
    • (2006) J Biol Chem , vol.281 , pp. 20865-20872
    • Wang, W.1    Lindsey-Boltz, L.A.2    Sancar, A.3    Bambara, R.A.4
  • 42
    • 10044272942 scopus 로고    scopus 로고
    • The human Rad9-1-Hus1 checkpoint complex stimulates flap endonuclease 1
    • Wang W, Brandt P, Rossi ML, et al. The human Rad9-1-Hus1 checkpoint complex stimulates flap endonuclease 1. Proc Natl Acad Sci U S A 2004;101:16762-7.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 16762-16767
    • Wang, W.1    Brandt, P.2    Rossi, M.L.3
  • 43
    • 33751100898 scopus 로고    scopus 로고
    • Physical and functional interactions between MutY glycosylase homologue (MYH) and checkpoint proteins Rad9-1-Hus1
    • Shi G, Chang DY, Cheng CC, Guan X, Venclovas C, Lu AL. Physical and functional interactions between MutY glycosylase homologue (MYH) and checkpoint proteins Rad9-1-Hus1. Biochem J 2006;400:53-62.
    • (2006) Biochem J , vol.400 , pp. 53-62
    • Shi, G.1    Chang, D.Y.2    Cheng, C.C.3    Guan, X.4    Venclovas, C.5    Lu, A.L.6
  • 44
    • 0035844130 scopus 로고    scopus 로고
    • ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation
    • Chen MJ, Lin YT, Lieberman HB, Chen G, Lee EY. ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation. J Biol Chem 2001;276:16580-6.
    • (2001) J Biol Chem , vol.276 , pp. 16580-16586
    • Chen, M.J.1    Lin, Y.T.2    Lieberman, H.B.3    Chen, G.4    Lee, E.Y.5
  • 45
    • 1942424060 scopus 로고    scopus 로고
    • Critical role for chicken Rad17 and Rad9 in the cellular response to DNA damage and stalled DNA replication
    • Kobayashi M, Hirano A, Kumano T, et al. Critical role for chicken Rad17 and Rad9 in the cellular response to DNA damage and stalled DNA replication. Genes Cells 2004;9:291-303.
    • (2004) Genes Cells , vol.9 , pp. 291-303
    • Kobayashi, M.1    Hirano, A.2    Kumano, T.3
  • 46
    • 15944424299 scopus 로고    scopus 로고
    • Human Rad9 is required for the activation of S-phase checkpoint and the maintenance of chromosomal stability
    • Dang T, Bao S, Wang XF. Human Rad9 is required for the activation of S-phase checkpoint and the maintenance of chromosomal stability. Genes Cells 2005;10:287-95.
    • (2005) Genes Cells , vol.10 , pp. 287-295
    • Dang, T.1    Bao, S.2    Wang, X.F.3
  • 47
    • 0036241988 scopus 로고    scopus 로고
    • c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage
    • Yoshida K, Komatsu K, Wang HG, Kufe D. c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage. Mol Cell Biol 2002;22:3292-300.
    • (2002) Mol Cell Biol , vol.22 , pp. 3292-3300
    • Yoshida, K.1    Komatsu, K.2    Wang, H.G.3    Kufe, D.4
  • 48
    • 0038237433 scopus 로고    scopus 로고
    • Protein kinase Cδ is responsible for constitutive and DNA damage-induced phosphorylation of Rad9
    • Yoshida K, Wang HG, Miki Y, Kufe D. Protein kinase Cδ is responsible for constitutive and DNA damage-induced phosphorylation of Rad9. EMBO J 2003;22:1431-41.
    • (2003) EMBO J , vol.22 , pp. 1431-1441
    • Yoshida, K.1    Wang, H.G.2    Miki, Y.3    Kufe, D.4
  • 49
    • 0033794570 scopus 로고    scopus 로고
    • Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis
    • Komatsu K, Miyashita T, Hang H, et al. Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis. Nat Cell Biol 2000;2:1-6.
    • (2000) Nat Cell Biol , vol.2 , pp. 1-6
    • Komatsu, K.1    Miyashita, T.2    Hang, H.3
  • 50
    • 2942691396 scopus 로고    scopus 로고
    • Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21
    • Yin Y, Zhu A, Jin YJ, et al. Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21. Proc Natl Acad Sci U S A 2004;101:8864-9.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8864-8869
    • Yin, Y.1    Zhu, A.2    Jin, Y.J.3


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