Allogeneic lymphocytes persist and traffic in feral MHC-matched Mauritian cynomolgus macaques

PLoS ONE

Volumn 3, Issue 6, 2008, Pages

  Greene, Justin M ^a   Burwitz, Benjamin J ^a   Blasky, Alex J ^b   Mattila, Teresa L ^c   Hong, Jung Joo ^c   Rakasz, Eva G ^b   Wiseman, Roger W ^b   Hasenkrug, Kim J ^d   Skinner, Pamela J ^c   O'Connor, Shelby L ^a   O'Connor, David H ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADOPTIVE TRANSFER; ANIMAL CELL; ARTICLE; BLOOD; CONTROLLED STUDY; DRUG DESIGN; FERAL ANIMAL; HLA MATCHING; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNIZATION; LYMPHOCYTE MIGRATION; LYMPHOCYTE SUBPOPULATION; LYMPHOID TISSUE; MACACA; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PATHOGENESIS; PRIMATE; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS LOAD; ANIMAL; CD8+ T LYMPHOCYTE; GENETICS; HAPLOTYPE; IMMUNOLOGY; NUCLEOTIDE SEQUENCE; WILD ANIMAL;

AIDS VIRUS; ANIMALIA; FRIEND MURINE LEUKEMIA VIRUS; MACACA; MUS; PRIMATES; SIMIAN IMMUNODEFICIENCY VIRUS;

MICROSATELLITE DNA; PRIMER DNA;

ADOPTIVE TRANSFER; ANIMALS; ANIMALS, WILD; BASE SEQUENCE; CD8-POSITIVE T-LYMPHOCYTES; DNA PRIMERS; HAPLOTYPES; MACACA FASCICULARIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROSATELLITE REPEATS; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 48649100890     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002384     Document Type: Article

References (47)

1. Pitisuttithum P, Gilbert P, Gurwith M, Heyward W, Martin M, et al. (2006) Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J Infect Dis 194: 1661-1671.
2. Watanabe ME (2003) Skeptical scientists skewer VaxGen statistics. Nat Med 9: 376.
3. Cohen J (2007) AIDS research. Did Merck's failed HIV vaccine cause harm? Science 318: 1048-1049.
4. Sekaly RP (2008) The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development? J Exp Med 205: 7-12.
5. Walker BD (2007) Elite control or HIV Infection: implications for vaccines and treatment. Top HIV Med 15: 134-136.
6. Yant LJ, Friedrich TC, Johnson RC, May GE, Maness NJ, et al. (2006) The high-frequency major histocompatibility complex class I allele Mamu-B*17 is associated with control of simian immunodeficiency virus SIVmac239 replication. J Virol 80: 5074-5077.
7. Loffredo JT, Maxwell J, Qi Y, Glidden CE, Borchardt GJ, et al. (2007) Mamu-B*08-positive macaques control simian immunodeficiency virus replication. J Virol 81: 8827-8832.
8. Migueles SA, Sabbaghian MS, Shupert WL, Bettinotti MP, Marincola FM, et al. (2000) HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors. Proc Natl Acad Sci U S A 97: 2709-2714.
9. Pereyra F, Addo MM, Kaufmann DE, Liu Y, Miura T, et al. (2008) Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy. J Infect Dis 197: 563-571.
10. Friedrich TC, Valentine LE, Yant LJ, Rakasz EG, Piaskowski SM, et al. (2007) Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication. J Virol 81: 3465-3476.
11. Baba TW, Jeong YS, Pennick D, Bronson R, Greene MF, et al. (1995) Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques. Science 267: 1820-1825.
12. Hofmann-Lehmann R, Vlasak J, Williams AL, Chenine AL, McClure HM, et al. (2003) Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation. AIDS 17: 157-166.
13. Dittmer U, Hasenkrug KJ (2001) Cellular and molecular mechanisms of vaccine-induced protection against retroviral infections. Curr Mol Med 1: 431-436.
14. Dittmer U, Brooks DM, Hasenkrug KJ (1999) Requirement for multiple lymphocyte subsets in protection by a live attenuated vaccine against retroviral infection. Nat Med 5: 189-193
15. Dittmer U, Brooks DM, Hasenkrug KJ (1999) Protection against establishment of retroviral persistence by vaccination with a live attenuated virus. J Virol 73: 3753-3757.
16. Hasenkrug KJ, Dittmer U (2007) Immune control and prevention of chronic Friend retrovirus infection. Front Biosci 12: 1544-1551.
17. de Groot N, Doxiadis GG, De Groot NG, Otting N, Heijmans C, et al. (2004) Genetic makeup of the DR region in rhesus macaques: gene content, transcripts, and pseudogenes. J Immunol 172: 6152-6157.
18. Bernstein WB, Cox JH, Aronson NE, Tracy L, Schlienger K, et al. (2004) Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons. Clin Immunol 111: 262-274.
19. Bex F, Hermans P, Sprecher S, Achour A, Badjou R, et al. (1994) Syngeneic adoptive transfer of anti-human immunodeficiency virus (HIV-1)-primed lymphocytes from a vaccinated HIV-seronegative individual to his HIV-1-infected identical twin. Blood 84: 3317-3326.
20. Hoffmann C, Stellbrink HJ, Dielschneider T, Degen O, Stoehr A, et al. (2007) Adoptive transfer of syngeneic T cells in HTV-1 discordant twins indicates rapid regulation of T-cell homeostasis. Br J Haematol.
21. Levine BL, Bernstein WB, Aronson NE, Schlienger K, Cone J, et al. (2002) Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection. Nat Med 8: 47-53.
22. Tan R, Wilson JD, Rostron T, Peto T, McMichael AJ, et al. (1998) Prolonged CD8+ T-cell expansions after adoptive transfer of syngeneic lymphocytes between HIV-discordant identical twins. AIDS 12: 2240-2241.
23. Villinger F, Brice GT, Mayne AE, Bostik P, Mori K, et al. (2002) Adoptive transfer of simian immunodeficiency virus (SIV) naive autologous CD4(+) cells to macaques chronically infected with SIV is sufficient to induce long-term nonprogressor status. Blood 99: 590-599.
24. Walker RE, Bechtel CM, Natarajan V, Baseler M, Hege KM, et al. (2000) Long-term in vivo survival of receptor-modified syngeneic T cells in patients with human immunodeficiency virus infection. Blood 96: 467-474.
25. Chea S, Dale CJ, De Rose R, Ramshaw IA, Kent SJ (2005) Enhanced cellular immunity in macaques following a novel peptide immunotherapy. J Virol 79: 3748-3757.
26. Berger C, Jensen MC, Lansdorp PM, Gough M, Elliott C, et al. (2008) Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates. J Clin Invest 118: 294-305.
27. Onlamoon N, Plagman N, Rogers KA, Mayne AE, Bostik P, et al. (2007) Anti-CD3/28 mediated expansion of macaque CD4+ T cells is polyclonal and provides extended survival after adoptive transfer. J Med Primatol 36: 206-218.
28. Joseph A, Zheng JH, Follenzi A, Dilorenzo T, Sango K, et al. (2008) Lentiviral Vectors Encoding HIV-1-specific TCR Genes Efficiently Convert Peripheral Blood CD8 T Lymphocytes Into Cytotoxic T Lymphocytes With Potent In Vitro and In Vivo HIV-1-specific Inhibitory Activity. J Virol.
29. Berger C, Blau CA, Huang ML, Iuliucci JD, Dalgarno DC, et al. (2004) Pharmacologically regulated Fas-mediated death of adoptively transferred T cells in a nonhuman primate model. Blood 103: 1261-1269.
30. Berger C, Flowers ME, Warren EH, Riddell SR (2006) Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation. Blood 107: 2294-2302.
31. Tan R, Xu X, Ogg GS, Hansasuta P, Dong T, et al. (1999) Rapid death of adoptively transferred T cells in acquired immunodeficiency syndrome. Blood 93: 1506-1510.
32. McKinney DM, Lewinsohn DA, Riddell SR, Greenberg PD, Mosier DE (1999) The antiviral activity of HIV-specific CD8+ CTL clones is limited by elimination due to encounter with HIV-infected targets. J Immunol 163: 861-867.
33. Johnson RP (2002) Mechanisms of protection against simian immunodeficiency virus infection. Vaccine 20: 1985-1987.
34. Koff WC, Johnson PR, Watkins DI, Burton DR, Lifson JD, et al. (2006) HIV vaccine design: insights from live attenuated SIV vaccines. Nat Immunol 7: 19-23.
35. Wiseman RW, Wojcechowskyj JA, Greene JM, Blasky AJ, Gopon T, et al. (2007) Simian Immunodeficiency Virus SIVmac239 Infection of Major Histocompatibility Complex-Identical Cynomolgus Macaques from Mauritius. J Virol 81: 349-361.
36. Karre K (2002) NK cells, MHC class I molecules and the missing self. Scand J Immunol 55: 221-228.
37. Karre K, Ljunggren HG, Piontek G, Kiessling R (1986) Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 319: 675-678.
38. Ljunggren HG, Karre K (1985) Host resistance directed selectively against H-2-deficient lymphoma variants. Analysis of the mechanism. J Exp Med 162: 1745-1759.
39. O'Connor SI, Blasky AJ, Pendley CJ, Becker EA, Wiseman RW, et al. (2007) Comprehensive characterization of MHC class II haplotypes in Mauritian cynomolgus macaques. Immunogenetics 59: 449-462.
40. Horan PK, Slezak SE (1989) Stable cell membrane labelling. Nature 340: 167-168.
41. Slezak SE, Horan PK (1989) Cell-mediated cytotoxicity. A highly sensitive and informative flow cytometric assay. J Immunol Methods 117: 205-214.
42. Schmitz JE, Forman MA, Lifton MA, Concepcion O, Reimann KAJ, et al. (1998) Expression of the CD8alpha beta-heterodimer on CDB(+) T lymphocytes in peripheral blood lymphocytes of human immunodeficiency virus- and human immunodeficiency virus+ individuals. Blood 92: 198-206.
43. Schmitz JE, Johnson RP, McClure HM, Manson KH, Wyand MS, et al. (2005) Effect of CD8+ lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239-delta3-vaccinated rhesus macaques. J Virol 79: 8131-8141.
44. Allen TM, Vogel TU, Fuller DH, Mothe BR, Steffen S, et al. (2000) Induction of AIDS virus-specific CTL activity in fresh, unstimulated peripheral blood lymphocytes from rhesus macaques vaccinated with a DNA prime/modified vaccinia virus Ankara boost regimen. J Immunol 164: 4968-4978.
45. DeMaria MA, Casto M, O'Connell M, Johnson RP, Rosenzweig M (2000) Characterization of lymphocyte subsets in rhesus macaques during the first year of life. Eur J Haematol 65: 245-257.
46. Penedo MC, Bontrop RE, Heijmans CM, Otting N, Noort R, et al. (2005) Microsatellite typing of the rhesus macaque MHC region. Immunogenetics 57: 198-209.
47. Kestler H Wr, Li Y, Naidu YM, Butler CV, Ochs MF, et al. (1988) Comparison of simlan immunodeficiency virus isolates. Nature 331: 619-622.