Formation of cholesterol-enriched structures by aberrant intracellular accumulation of ATP-binding cassette transporter A1

Genes to Cells

Volumn 13, Issue 8, 2008, Pages 889-904

  Tanaka, Arowu R ^a   Kano, Fumi ^a   Yamamoto, Akitsugu ^b   Ueda, Kazumitsu ^c   Murata, Masayuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NAGAHAMA INSTITUTE OF BIO SCIENCE AND TECHNOLOGY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; CHOLESTEROL; GREEN FLUORESCENT PROTEIN; LACTACYSTIN; LOW DENSITY LIPOPROTEIN; PROTEASOME; PROTEASOME INHIBITOR; RAB PROTEIN;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL COMPARTMENTALIZATION; CELL SELECTION; CELL STRAIN HEK293; CELL VACUOLE; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; ENZYME ACTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; INTERNALIZATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM;

ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; CHOLESTEROL; HUMANS; MACROPHAGES, PERITONEAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN TRANSPORT; RAB4 GTP-BINDING PROTEINS; RECEPTORS, SCAVENGER; TRANSPORT VESICLES;

EID: 48649083059     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2008.01213.x     Document Type: Article

References (40)

1. Abe-Dohmae, S., Ueda, K. & Yokoyama, S. (2006) ABCA7, a molecule with unknown function. FEBS Lett. 580, 1178-1182.
2. Amaral, M.D. (2004) CFTR and chaperones: Processing and degradation. J. Mol. Neurosci. 23, 41-48.
3. Arakawa, R. & Yokoyama, S. (2002) Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation. J. Biol. Chem. 277, 22426-22429.
4. Audhya, A., Desai, A. & Oegema, K. (2007) A role for Rab5 in structuring the endoplasmic reticulum. J. Cell Biol. 178, 43-56.
5. Boadu, E. & Francis, G.A. (2006) The role of vesicular transport in ABCA1-dependent lipid efflux and its connection with NPC pathways. J. Mol. Med. 84, 266-275.
6. Bodzioch, M., Orso, E., Klucken, J., et al. (1999) The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nat. Genet. 22, 347-351.
7. Brooks-Wilson, A., Marcil, M., Clee, S.M., et al. (1999) Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat. Genet. 22, 336-345.
8. Chen, W., Sun, Y., Welch, C., Gorelik, A., Leventhal, A.R., Tabas, I. & Tall, A.R. (2001) Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes. J. Biol. Chem. 276, 43564-43569.
9. Cormont, M. & Le Marchand-Brustel, Y. (2001) The role of small G-proteins in the regulation of glucose transport. Mol. Membr. Biol. 18, 213-220.
10. Cormont, M., Bortoluzzi, M.N., Gautier, N., Mari, M., van Obberghen, E. & Le Marchand-Brustel, Y. (1996) Potential role of Rab4 in the regulation of subcellular localization of Glut4 in adipocytes. Mol. Cell. Biol. 16, 6879-6886.
11. Dean, M. (2005) The genetics of ATP-binding cassette transporters. Methods Enzymol. 400, 409-429.
12. Hamon, Y., Broccardo, C., Chambenoit, O., Luciani, M.F., Toti, F., Chaslin, S., Freyssinet, J.M., Devaux, P.F., McNeish, J., Marguet, D. & Chimini, G. (2000) ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine. Nat. Cell Biol. 2, 399-406.
13. Hatsuzawa, K., Hirose, H., Tani, K., Yamamoto, A., Scheller, R.H. & Tagaya, M. (2000) Syntaxin 18, a SNAP receptor that functions in the endoplasmic reticulum, intermediate compartment, and cis-Golgi vesicle trafficking. J. Biol. Chem. 275, 13713-13720.
14. Imamura, T., Huang, J., Usui, I., Satoh, H., Bever, J. & Olefsky, J.M. (2003) Insulin-induced GLUT4 translocation involves protein kinase C-λ-mediated functional coupling between Rab4 and the motor protein kinesin. Mol. Cell. Biol. 23, 4892-4900.
15. Johnston, J.A., Ward, C.L. & Kopito, R.R. (1998) Aggresomes: A cellular response to misfolded proteins. J. Cell Biol. 143, 1883-1898.
16. Jones, M.C., Caswell, P.T. & Norman, J.C. (2006) Endocytic recycling pathways: Emerging regulators of cell migration. Curr. Opin. Cell Biol. 18, 549-557.
17. Kerem, B.S., Buchanan, J.A., Durie, P., Corey, M.L., Levison, H., Rommens, J.M., Buchwald, M. & Tsui, L.C. (1989) DNA marker haplotype association with pancreatic sufficiency in cystic fibrosis. Am. J. Hum. Genet. 44, 827-834.
18. MacQueen, J.B. (1967) Some methods for classification and analysis of multivariate observations. Proceedings of 5th Berkeley Symposium on Mathematical Statistics and Probability, University of California Press, Berkely, CA, pp. 281-297.
19. McNeish, J., Aiello, R.J., Guyot, D., Turi, T., Gabel, C., Aldinger, C., Hoppe, K.L., Roach, M.L., Royer, L.J., de Wet, J., Broccardo, C., Chimini, G. & Francone, O.L. (2000) High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1. Proc. Natl. Acad. Sci. USA 97, 4245-4250.
20. Mendez, A.J. (1997) Cholesterol efflux mediated by apolipoproteins is an active cellular process distinct from efflux mediated by passive diffusion. J. Lipid Res. 38, 1807-1821.
21. Nagata, K., Yamamoto, A., Ban, N., Tanaka, A.R., Matsuo, M., Kioka, N., Inagaki, N. & Ueda, K. (2004) Human ABCA3, a product of a responsible gene for abca3 for fatal surfactant deficiency in newborns, exhibits unique ATP hydrolysis activity and generates intracellular multilamellar vesicles. Biochem. Biophys. Res. Commun. 324, 262-268.
22. Neufeld, E.B., Remaley, A.T., Demosky, S.J., Stonik, J.A., Cooney, A.M., Comly, M., Dwyer, N.K., Zhang, M., Blanchette-Mackie, J., Santamarina-Fojo, S. & Brewer, H.B. Jr. (2001) Cellular localization and trafficking of the human ABCA1 transporter. J. Biol. Chem. 276, 27584-27590.
23. Neufeld, E.B., Stonik, J.A., Demosky, S.J. Jr., Knapper, C.L., Combs, C.A., Cooney, A., Comly, M., Dwyer, N., Blanchette-Mackie, J., Remaley, A.T., Santamarina-Fojo, S. & Brewer, H.B. Jr (2004) The ABCA1 transporter modulates late endocytic trafficking: Insights from the correction of the genetic defect in Tangier disease. J. Biol. Chem. 279, 15571-15578.
24. Oram, J.F. & Yokoyama, S. (1996) Apolipoprotein-mediated removal of cellular cholesterol and phospholipids. J. Lipid Res. 37, 2473-2491.
25. Orso, E., Broccardo, C., Kaminski, W.E., et al. (2000) Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and ABC1-deficient mice. Nat. Genet. 24, 192-196.
26. Pagano, A., Crottet, P., Prescianotto-Baschong, C. & Spiess, M. (2004) In vitro formation of recycling vesicles from endosomes requires adaptor protein-1/clathrin and is regulated by rab4 and the connector rabaptin-5. Mol. Biol. Cell 15, 4990-5000.
27. Rust, S., Rosier, M., Funke, H., Real, J., Amoura, Z., Piette, J.C., Deleuze, J.F., Brewer, H.B., Duverger, N., Denèfle, P. & Assmann, G. (1999) Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat. Genet. 22, 352-355.
28. Saxena, S.K., Kaur, S. & George, C. (2006) Rab4GTPase modulates CFTR function by impairing channel expression at plasma membrane. Biochem. Biophys. Res. Commun. 341, 184-191.
29. Smith, J.D., Waelde, C., Horwitz, A. & Zheng, P. (2002) Evaluation of the role of phosphatidylserine translocase activity in ABCA1-mediated lipid efflux. J. Biol. Chem. 277, 17797-17803.
30. Sonnichsen, B., De Renzis, S., Nielsen, E., Rietdorf, J. & Zerial, M. (2000) Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11. J. Cell Biol. 149, 901-914.
31. Takahashi, K., Kimura, Y., Kioka, N., Matsuo, M. & Ueda, K. (2006) Purification and ATPase activity of human ABCA1. J. Biol. Chem. 281, 10760-10768.
32. Takahashi, K., Kimura, Y., Nagata, K., Yamamoto, A., Matsuo, M. & Ueda, K. (2005) ABC proteins: Key molecules for lipid homeostasis. Med. Mol. Morphol. 38, 2-12.
33. Takahashi, Y. & Smith, J.D. (1999) Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway. Proc. Natl. Acad. Sci. USA 96, 11358-11363.
34. Tanaka, A.R., Abe-Dohmae, S., Ohnishi, T., Aoki, R., Morinaga, G., Okuhira, K., Ikeda, Y., Kano, F., Matsuo, M., Kioka, N., Amachi, T., Murata, M., Yokoyama, S. & Ueda, K. (2003) Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis. J. Biol. Chem. 278, 8815-8819.
35. Tanaka, A.R., Ikeda, Y., Abe-Dohmae, S., Arakawa, R., Sadanami, K., Kidera, A., Nakagawa, S., Nagase, T., Aoki, R., Kioka, N., Amachi, T., Yokoyama, S. & Ueda, K. (2001) Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjogren's Syndrome. Biochem. Biophys. Res. Commun. 283, 1019-1025.
36. van der Sluijs, P., Hull, M., Webster, P., Male, P., Goud, B. & Mellman, I. (1992) The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway. Cell 70, 729-740.
37. Vieira, O., Escargueil-Blanc, I., Jurgens, G., Borner, C., Almeida, L., Salvayre, R. & Nègre-Salvayre, A. (2000) Oxidized LDLs alter the activity of the ubiquitin-proteasome pathway: Potential role in oxidized LDL-induced apoptosis. FASEB J. 14, 532-542.
38. Voeltz, G.K., Rolls, M.M. & Rapoport, T.A. (2002) Structural organization of the endoplasmic reticulum. EMBO Rep. 3, 944-950.
39. Weng, J., Mata, N.L., Azarian, S.M., Tzekov, R.T., Birch, D.G. & Travis, G.H. (1999) Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in ABCR knockout mice. Cell 98, 13-23.
40. Yan, F., Lin, C.W., Weisiger, E., Cartier, E.A., Taschenberger, G. & Shyng, S.L. (2004) Sulfonylureas correct trafficking defects of ATP-sensitive potassium channels caused by mutations in the sulfonylurea receptor. J. Biol. Chem. 279, 11096-11105.