Human ABCA3, a product of a responsible gene for abca3 for fatal surfactant deficiency in newborns, exhibits unique ATP hydrolysis activity and generates intracellular multilamellar vesicles

Biochemical and Biophysical Research Communications

Volumn 324, Issue 1, 2004, Pages 262-268

  Nagata, Koh ^a   Yamamoto, Akitsugu ^b   Ban, Nobuhiro ^c   Tanaka, Arowu R ^a   Matsuo, Michinori ^a   Kioka, Noriyuki ^a   Inagaki, Nobuya ^c   Ueda, Kazumitsu ^a  

^a KYOTO UNIVERSITY   (Japan)

^b NAGAHAMA INSTITUTE OF BIO SCIENCE AND TECHNOLOGY   (Japan)

^c AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ABC proteins; ABCA3; ATPase; Cholesterol; Lamellar body; Photoaffinity label; Pulmonary surfactant

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A3; ADENOSINE TRIPHOSPHATASE; CHOLESTEROL; LUNG SURFACTANT; METAL ION; METHYL BETA CYCLODEXTRIN; ORTHOVANADIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL VACUOLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; EMBRYO; ENZYME ACTIVITY; FATALITY; GENE EXPRESSION; GENE FUNCTION; HOST CELL; HUMAN; HUMAN CELL; HYDROLYSIS; INCUBATION TIME; LAMELLAR BODY; LIPID STORAGE; PHOTOAFFINITY LABELING; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ATP-BINDING CASSETTE TRANSPORTERS; BETA-CYCLODEXTRINS; CELL FRACTIONATION; CELL LINE; CELL MEMBRANE; CYTOPLASMIC VESICLES; HUMANS; INFANT; INFANT, NEWBORN; METALS; MUTATION; NUCLEOTIDES; PHOTOAFFINITY LABELS; PULMONARY SURFACTANTS; VANADATES;

EID: 4744347103     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.09.043     Document Type: Article

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