Effect of bacterial lipopolysaccharide on the reproductive axis of prepubertal and peripubertal female rats: Ontogenic changes in the immune-neuroendocrine interactions

NeuroImmunoModulation

Volumn 15, Issue 2, 2008, Pages 125-130

  Reynoso, Roxana ^a   Ponzo, Osvaldo ^a   Cardoso, Nancy ^a   Szwarcfarb, Berta ^a   Carbone, Silvia ^a   Moguilevsky, Jaime ^a   Scacchi, Pablo ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

GABA; Glutamate; Gn RH; Leptin; Lipopolysaccharide; Nitric oxide synthase; Sexual maturation

Indexed keywords

4 AMINOBUTYRIC ACID; BACTERIUM LIPOPOLYSACCHARIDE; GLUTAMIC ACID; GONADORELIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LEPTIN; LUTEINIZING HORMONE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; LUTEINIZING HORMONE BLOOD LEVEL; NEUROENDOCRINE SYSTEM; NONHUMAN; PREPUBERTY; PRIORITY JOURNAL; PUBERTY; RADIOIMMUNOASSAY; RAT; REPRODUCTION; SALMONELLA TYPHI; SEXUAL MATURATION;

ADIPOSE TISSUE; AGING; ANIMALS; BACTERIAL INFECTIONS; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GONADOTROPIN-RELEASING HORMONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; HYPOTHALAMUS; INFLAMMATION MEDIATORS; LEPTIN; LIPOPOLYSACCHARIDES; LUTEINIZING HORMONE; NEUROIMMUNOMODULATION; NEUROSECRETORY SYSTEMS; NITRIC OXIDE SYNTHASE; RATS; RATS, WISTAR; REPRODUCTION; SEXUAL MATURATION; STRESS; UP-REGULATION;

EID: 48449104269     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000148195     Document Type: Article

References (30)

1. McCann SM, Kimura M, Karanth S, Yu W, Mastronardi C, Rettori V: The mechanism of action of cytokines to control the release of hypothalamic and pituitary hormones in infection. Ann NY Acad Sci 2000;917:4-18.
2. Watanobe H, Hayakawa Y: Hypothalamic interleukin-1β and tumor necrosis factor-α, but not interleukin-6, mediate the endotoxin-induced suppression of the reproductive axis in rats. Endocrinology 2003;144:4868-4875.
3. Moguilevsky JA, Wuttke W: Changes in the control of gonadotrophin secretion by neurotransmitters during sexual development in rats. Exp Clin Endocrinol Diabetes 2001;109:188-195.
4. Dawson VL, Dawson TM: Nitric oxide in neuronal degeneration. Proc Soc Expl Biol Med 1996;211:1.
5. Moschos S, Chan J, Mantzoros C: Leptin and reproduction: a review. Fertil Steril 2002;77:433-444.
6. Rettori V, Belova N, Dees LW, Nyberg C, Gimeno M, McCann S: Role of nitric oxide in the control of luteinizing hormone-releasing hormone release in vivo and in vitro. Proc Natl Acad Sci USA 1993;90:10130-10134.
7. Wong ML, Rettori V, al-Shekhlee A, et al: Inducible nitric oxide synthase gene expression in the brain during systemic inflammation. Nat Med 1996;2:581-584.
8. Rettori V, Kamat A, McCann SM: Nitric oxide mediates the stimulation of luteinizing-hormone releasing hormone release induced by glutamic acid in vitro. Brain Res Bull 1993;33:501.
9. Canteros G, Rettori V, Genaro A, et al: Nitric oxide synthase content of hypothalamic explants: increased by norepinephrine and inactivated by NO and cGMP. Proc Natl Acad Sci USA 1996;93:4246.
10. Ponzo OJ, Szwarcfarb B, Rondina D, Carbone S, Reynoso R, Scacchi P, Moguilevsky JA: Changes in the sensitivity of gonadotrophin axis to leptin during sexual maturation in female rats. Neuroendocrinol Lett 2001;22:427-431.
11. Reynoso R, Ponzo OJ, Szwarcfarb B, Rondina D, Carbone S, Rimoldi G, Scacchi P, Moguilevsky JA: Effect of leptin on hypothalamic release of GnRH and neurotransmitter amino acids during sexual maturation in female rats. Exp Clin Endocrinol Diabetes 2003;111:274-277.
12. Reynoso R, Cardoso N, Szwarcfarb B, Carbone S, Ponzo O, Moguilevsky JA, Scacchi P: Nitric oxide synthase inhibition prevents leptin induced Gn-RH release in prepubertal and peripubertal female rats. Exp Clin Endocrinol Diabetes 2007;115:423-427.
13. Mastronardi CA, Yu WH, McCann SM: Lipopolysaccharide induced leptin release is neurally controlled. Proc Natl Acad Sci USA 2001;98:14720-14725.
14. Spinedi E, Chisari A, Pralong F, Gaillard RC: Sexual dimorphism in the mouse hypothalamic-pituitary-adrenal axis function after endotoxin and insulin stresses during development. Neuroimmunomodulation 1997;4:77-83.
15. Bredt D, Snyder S: Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc Natl Acad Sci USA 1990;87:682.
16. Jarry H, Hirsch B, Leonhardt S, Wuttke W: Amino acid neurotransmitter release in the preoptic area of rats during the positive feedback actions of estradiol on LH release. Neuroendocrinology 1992;56:133-140.
17. Spangelo Bl, Gorospe WC: Role of cytokines in the neuroendocrine-immune system axis. Front Neuroendocrinol 1995;16:1-22.
18. Wong ML, Bongiorno V, Rettori V, et al: Interleukin 1 beta, IL-1 receptor antagonist, IL-10, and IL-3 gene expression in the central nervous system and anterior pituitary during systemic inflammation: pathophysiology implications. Proc Natl Acad Sci USA 1997;94:227.
19. Kakizaki Y, Watanobe A, Kohsaka A, Suda T: Temporal profiles of interleukin-1β, interleukin 6 and tumor necrosis factor-alpha in the plasma and hypothalamic paraventricular nucleus after intravenous or intraperitoneal administration of lipopolysaccharide in the rat: estimation by push-pull perfusion. Endocr J 1999;46:487-496.
20. Harada S, Imaki T, Chicaga N, Narusz M, Lemura H: Distinct distribution and time course changes in neuronal nitric oxide synthase and inducible NOS in paraventricular nucleus following lipopolysaccharide injection. Brain Res 1999;821:322-332.
21. McCann SM, Kimura M, Karanth S, Yu W, Mastronardi C, Rettori V: The mechanism of action of cytokines to control the release of hypothalamic and pituitary hormones in infection. Ann NY Acad Sci 2000;917:4-18.
22. Feleder C, Jarry H, Leonhardt S, Moguilevsky JA, Wuttke W: Effects of endotoxin on in vitro release of LHRH and amino acid neurotransmitters by preoptic mediobasal hypothalamic fragments. Neuroimmunomodulation 1996;3:76-81.
23. Feleder C, Refojo D, Jarry H, Wuttke W, Moguilevsky JA: Bacterial endotoxin inhibits LH-RH secretion following the increased release of hypothalamic GABA levels. Different effects on amino acid neurotransmitter release. Neuroimmunomodulation 1996;3:342.
24. Feleder C, Arias P, Refojo D, Nacht S, Moguilevsky J: Age-related differences in the effects of bacterial endotoxin (LPS) upon the release of LH-RH, gonadotropins and hypothalamic inhibitory amino acid neurotransmitters measured in tissues explanted from intact male rats. Exp Clin Endocrinol Diabetes 2000;108:220-227.
25. Feleder C, Refojo D, Natch S, Moguilevsky J: Interleukin-1 stimulates inhibitory hypothalamic amino acid neurotransmitter release. Neuroimmunomodulation 1998;5:1-4.
26. Hansen M, Taishi P, Chen Z, Krueger J: Vagotomy blocks the induction of interleukin-1 beta mRNA in the brain of rats in response to systemic IL-1 beta. J Neurosci 1998;6:2247.
27. Rinaman L: Postnatal developmental of hypothalamic inputs to the dorsal vagal complex in rats. Physiol Behav 2003;79:65.
28. LayéS, BluthéRM, Kent S, Combre C, Medina C, Partner P, Kelley K, Dantzer R: Subdiaphragmatic vagotomy blocks the induction of interleukin 1 beta mRNA in the brain of mice in response to peripherally administered lipopolysaccharide. Am J Physiol 1995;268:1327.
29. Akira S, Takeda K, Kaisho T: Toll-like receptors: critical proteins linking innate acquired immunity. Nat Immunol 2001;2:675-680.
30. Yerkovich ST, Wikström ME, Suriyaarachchi D, Prescott SL, Upham JW, Holt PG: Postnatal development of monocyte cytokine responses to bacterial lipopolysaccharide. Pediatr Res 2007;62:547-552.