Sulfasalazine down-regulates the expression of the angiogenic factors platelet-derived endothelial cell growth factor/thymidine phosphorylase and interleukin-8 in human monocytic-macrophage THP1 and U937 cells

Molecular Pharmacology

Volumn 66, Issue 4, 2004, Pages 1054-1060

  De Bruin, Michiel ^a   Peters, Godefridus J ^a   Oerlemans, Ruud ^a   Assaraf, Yehuda G ^b   Masterson, Allan J ^a   Adema, Auke D ^a   Dijkmans, Ben A C ^a   Pinedo, Herbert M ^a   Jansen, Gerrit ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

5' DEOXYFLUOROURIDINE; ANGIOGENIC FACTOR; BETA ACTIN; DOXORUBICIN; FLOXURIDINE; GAMMA INTERFERON; INTERLEUKIN 8; METHOTREXATE; PLATELET DERIVED ENDOTHELIAL CELL GROWTH FACTOR; SALAZOSULFAPYRIDINE; THYMIDINE PHOSPHORYLASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL STRAIN U937; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG EXPOSURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IC 50; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION;

ANGIOGENESIS INDUCING AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, WESTERN; GENE EXPRESSION; HUMANS; INTERLEUKIN-8; MACROPHAGES; MONOCYTES; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; RECEPTORS, INTERFERON; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; RNA, MESSENGER; SULFASALAZINE; THYMIDINE PHOSPHORYLASE; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS; U937 CELLS;

EID: 4844229629     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.104.000315     Document Type: Article

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