TRIP12 functions as an E3 ubiquitin ligase of APP-BP1

Biochemical and Biophysical Research Communications

Volumn 374, Issue 2, 2008, Pages 294-298

  Park, Yoon ^a   Yoon, Sungjoo Kim ^b   Yoon, Jong Bok ^a  

^a Yonsei University   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

APP BP1; E3 ubiquitin ligase; NEDD8; Protein degradation; TRIP12

Indexed keywords

APP BP1 PROTEIN; CUL1 PROTEIN; HETERODIMER; MONOMER; RECOMBINANT PROTEIN; TRIP12 PROTEIN; UBIQUITIN PROTEIN LIGASE E3;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; HYBRID; IMMUNOPRECIPITATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; SEQUENCE HOMOLOGY; UBIQUITINATION; YEAST;

CARRIER PROTEINS; CATALYSIS; CULLIN PROTEINS; DIMERIZATION; DNA-BINDING PROTEINS; HUMANS; IMMUNOPRECIPITATION; PROTEIN STRUCTURE, TERTIARY; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; UBIQUITINS;

EID: 48349146368     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.07.019     Document Type: Article

References (25)

1. Kerscher O., Felberbaum R., and Hochstrasser M. Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu. Rev. Cell Dev. Biol. 22 (2006) 159-180
2. Pan Z.Q., Kentsis A., Dias D.C., Yamoah K., and Wu K. Nedd8 on cullin: building an expressway to protein destruction. Oncogene 23 (2004) 1985-1997
3. Bosu D.R., and Kipreos E.T. Cullin-RING ubiquitin ligases: global regulation and activation cycles. Cell Dev. 3 (2008) 7
4. Read M.A., Brownell J.E., Gladysheva T.B., Hottelet M., Parent L.A., Coggins M.B., Pierce J.W., Podust V.N., Luo R.S., Chau V., and Palombella V.J. Nedd8 modification of cul-1 activates SCF(beta-(TrCP))-dependent ubiquitination of IkappaBalpha. Mol. Cell. Biol. 20 (2000) 2326-2333
5. Morimoto M., Nishida T., Honda R., and Yasuda H. Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1). Biochem. Biophys. Res. Commun. 270 (2000) 1093-1096
6. Podust V.N., Brownell J.E., Gladysheva T.B., Luo R.S., Wang C., Coggins M.B., Pierce J.W., Lightcap E.S., and Chau V. A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination. Proc. Natl. Acad. Sci. USA 97 (2000) 4579-4584
7. Wu K., Chen A., and Pan Z.Q. Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization. J. Biol. Chem. 275 (2000) 32317-32324
8. Xirodimas D.P., Saville M.K., Bourdon J.C., Hay R.T., and Lane D.P. Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity. Cell 118 (2004) 83-97
9. Watson I.R., Blanch A., Lin D.C., Ohh M., and Irwin M.S. Mdm2-mediated NEDD8 modification of TAp73 regulates its transactivation function. J. Biol. Chem. 281 (2006) 34096-34103
10. Stickle N.H., Chung J., Klco J.M., Hill R.P., Kaelin Jr. W.G., and Ohh M. pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development. Mol. Cell. Biol. 24 (2004) 3251-3261
11. Oved S., Mosesson Y., Zwang Y., Santonico E., Shtiegman K., Marmor M.D., Kochupurakkal B.S., Katz M., Lavi S., Cesareni G., and Yarden Y. Conjugation to Nedd8 instigates ubiquitylation and down-regulation of activated receptor tyrosine kinases. J. Biol. Chem. 281 (2006) 21640-21651
12. Gao F., Cheng J., Shi T., and Yeh E.T. Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFkB-dependent transcription. Nat. Cell Biol. 8 (2006) 1171-1177
13. Osaka F., Kawasaki H., Aida N., Saeki M., Chiba T., Kawashima S., Tanaka K., and Kato S. A new NEDD8-ligating system for cullin-4A. Genes Dev. 12 (1998) 2263-2268
14. Gong L., and Yeh E.T.H. Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway. J. Biol. Chem. 274 (1999) 12036-12042
15. Walden H., Podgorski M.S., and Schulman B.A. Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8. Nature 422 (2003) 330-334
16. Huang D.T., Hunt H.W., Zhuang M., Ohi M.D., Holton J.M., and Schulman B.A. Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity. Nature 445 (2007) 394-398
17. Chow N., Korenberg J.R., Chen X.N., and Neve R.L. APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein. J. Biol. Chem. 271 (1996) 11339-11346
18. Chen Y., McPhie D.L., Hirschberg J., and Neve R.L. The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons. J. Biol. Chem. 275 (2000) 8929-8935
19. Laifenfeld D., Patzek L.J., McPhie D.L., Chen Y., Levites Y., Cataldo A.M., and Neve R.L. Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis. J. Neurosci. 27 (2007) 7141-7153
20. Johnson E.S., Ma P.C.M., Ota I.M., and Varshavsky A. A proteolytic pathway that recognizes ubiquitin as a degradation signal. J. Biol. Chem. 275 (1995) 17442-17456
21. Min K.W., Hwang J.W., Lee J.S., Park Y., Tamura T.A., and Yoon J.B. TIP120A associates with cullins and modulates ubiquitin ligase activity. J. Biol. Chem. 278 (2003) 15905-15910
22. Hwang J.W., Min K.W., Tamura T.A., and Yoon J.B. TIP120A associates with unneddylated cullin 1 and regulates its neddylation. FEBS Lett. 541 (2003) 102-108
23. Coates J.C. Armadillo repeat proteins: beyond the animal kingdom. Trends Cell Biol. 13 (2003) 463-471
24. Aravind L. The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation. Trends Biochem. Sci. 26 (2001) 273-275
25. Koegl M., Hoppe T., Schlenker S., Ulrich H.D., Mayer T.U., and Jentsch S. A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell 96 (1999) 635-644