-
1
-
-
33947605898
-
Attributable mortality of nosocomial Acinetobacter bacteremia
-
Grupper M, Sprecher H, Mashiach T, Finkelstein R: Attributable mortality of nosocomial Acinetobacter bacteremia. Infect Control Hosp Epidemiol (2007) 28(3):293-298.
-
(2007)
Infect Control Hosp Epidemiol
, vol.28
, Issue.3
, pp. 293-298
-
-
Grupper, M.1
Sprecher, H.2
Mashiach, T.3
Finkelstein, R.4
-
2
-
-
36649005520
-
Clinical features and outcome of community-onset bloodstream infections caused by extended-spectrum β-lactamase-producing Escherichia coli
-
Kang CI, Cheong HS, Chung DR, Peck KR, Song JH, Oh MD, Choe KW: Clinical features and outcome of community-onset bloodstream infections caused by extended-spectrum β-lactamase-producing Escherichia coli. Eur J Clin Microbiol Infect Dis (2008) 27(1):85-88.
-
(2008)
Eur J Clin Microbiol Infect Dis
, vol.27
, Issue.1
, pp. 85-88
-
-
Kang, C.I.1
Cheong, H.S.2
Chung, D.R.3
Peck, K.R.4
Song, J.H.5
Oh, M.D.6
Choe, K.W.7
-
3
-
-
34748886076
-
Burden of community-onset bloodstream infection: A population-based assessment
-
Interesting population-based surveillance study of community-onset bloodstream infections and their impact on morbidity, mortality and length of hospital stay, •
-
Laupland KB, Gregson DB, Flemons WW, Hawkins D, Ross T, Church DL: Burden of community-onset bloodstream infection: A population-based assessment. Epidemiol Infect (2007) 135(6):1037-1042. • Interesting population-based surveillance study of community-onset bloodstream infections and their impact on morbidity, mortality and length of hospital stay.
-
(2007)
Epidemiol Infect
, vol.135
, Issue.6
, pp. 1037-1042
-
-
Laupland, K.B.1
Gregson, D.B.2
Flemons, W.W.3
Hawkins, D.4
Ross, T.5
Church, D.L.6
-
4
-
-
33845719937
-
Antibacterial discovery and development - the failure of success?
-
Fernandes P: Antibacterial discovery and development - the failure of success? Nat Biotechnol (2006) 24(12):1497-1503.
-
(2006)
Nat Biotechnol
, vol.24
, Issue.12
, pp. 1497-1503
-
-
Fernandes, P.1
-
5
-
-
34249719971
-
New strategies for combating multidrug-resistant bacteria
-
Wright GD, Sutherland AD: New strategies for combating multidrug-resistant bacteria. Trends Mol Med (2007) 13(6):260-267.
-
(2007)
Trends Mol Med
, vol.13
, Issue.6
, pp. 260-267
-
-
Wright, G.D.1
Sutherland, A.D.2
-
6
-
-
34548472399
-
Alternatives to vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections
-
Micek ST: Alternatives to vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections. Clin Infect Dis (2007) 45(Suppl 3):S184-S190.
-
(2007)
Clin Infect Dis
, vol.45
, Issue.SUPPL. 3
-
-
Micek, S.T.1
-
7
-
-
33747589695
-
Challenges in identifying new antimicrobial agents effective for treating infections with Acinetobacter baumannii and Pseudomonas aeruginosa
-
Rice LB: Challenges in identifying new antimicrobial agents effective for treating infections with Acinetobacter baumannii and Pseudomonas aeruginosa. Clin Infect Dis (2006) 43(Suppl 2):S100-S105.
-
(2006)
Clin Infect Dis
, vol.43
, Issue.SUPPL. 2
-
-
Rice, L.B.1
-
8
-
-
33646948881
-
Antimicrobial resistance in Gram-positive bacteria
-
Rice LB: Antimicrobial resistance in Gram-positive bacteria. Am J Infect Control (2006) 34(5 Suppl 1):S11-S19.
-
(2006)
Am J Infect Control
, vol.34
, Issue.5 SUPPL. 1
-
-
Rice, L.B.1
-
9
-
-
33846161259
-
Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistant Staphylococcus aureus
-
Stevens DL, Ma Y, Salmi DB, McIndoo E, Wallace RJ, Bryant AE: Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistant Staphylococcus aureus. J Infect Dis (2007) 195(2):202-211.
-
(2007)
J Infect Dis
, vol.195
, Issue.2
, pp. 202-211
-
-
Stevens, D.L.1
Ma, Y.2
Salmi, D.B.3
McIndoo, E.4
Wallace, R.J.5
Bryant, A.E.6
-
10
-
-
33144473431
-
-
Talbot GH, Bradley J, Edwards JE Jr, Gilbert D, Scheld M, Bartlett JG: Bad bugs need drugs: An update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clin Infect Dis (2006) 42(5):657-668. • An important review and position paper from the relevant committee of the Infectious Diseases Society of America on drugs in late-stage development that could potentially be effective against resistant pathogens.
-
Talbot GH, Bradley J, Edwards JE Jr, Gilbert D, Scheld M, Bartlett JG: Bad bugs need drugs: An update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clin Infect Dis (2006) 42(5):657-668. • An important review and position paper from the relevant committee of the Infectious Diseases Society of America on drugs in late-stage development that could potentially be effective against resistant pathogens.
-
-
-
-
11
-
-
33746121117
-
Secular trends of antimicrobial resistance of blood isolates in a newly founded Greek hospital
-
Falagas ME, Kasiakou SK, Nikita D, Morfou P, Georgoulias G, Rafailidis PI: Secular trends of antimicrobial resistance of blood isolates in a newly founded Greek hospital. BMC Infect Dis (2006) 6:99.
-
(2006)
BMC Infect Dis
, vol.6
, pp. 99
-
-
Falagas, M.E.1
Kasiakou, S.K.2
Nikita, D.3
Morfou, P.4
Georgoulias, G.5
Rafailidis, P.I.6
-
12
-
-
33646550883
-
Secular trends of blood isolates in patients from a rural area population hospitalized in a tertiary center in a small city in Greece
-
Falagas ME, Bakossi A, Pappas VD, Holevas PV, Bouras A, Stamata E: Secular trends of blood isolates in patients from a rural area population hospitalized in a tertiary center in a small city in Greece. BMC Microbiol (2006) 6:41.
-
(2006)
BMC Microbiol
, vol.6
, pp. 41
-
-
Falagas, M.E.1
Bakossi, A.2
Pappas, V.D.3
Holevas, P.V.4
Bouras, A.5
Stamata, E.6
-
13
-
-
3142726042
-
Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program
-
Hajjeh RA, Sofair AN, Harrison LH, Lynn GM, Arthington-Skaggs BA, Mirza SA, Phelan M, Morgan J, Lee-Yang W, Ciblak MA, Benjamin LE et al: Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program. J Clin Microbiol (2004) 42(4):1519-1527.
-
(2004)
J Clin Microbiol
, vol.42
, Issue.4
, pp. 1519-1527
-
-
Hajjeh, R.A.1
Sofair, A.N.2
Harrison, L.H.3
Lynn, G.M.4
Arthington-Skaggs, B.A.5
Mirza, S.A.6
Phelan, M.7
Morgan, J.8
Lee-Yang, W.9
Ciblak, M.A.10
Benjamin, L.E.11
-
14
-
-
10744224705
-
Antifungal susceptibility survey of 2,000 bloodstream Candida isolates in the United States
-
Ostrosky-Zeichner L, Rex JH, Pappas PG, Hamill RJ, Larsen RA, Horowitz HW, Powderly WG, Hyslop N, Kauffman CA, Cleary J, Mangino JE et al: Antifungal susceptibility survey of 2,000 bloodstream Candida isolates in the United States. Antimicrob Agents Chemother (2003) 47(10):3149-3154.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, Issue.10
, pp. 3149-3154
-
-
Ostrosky-Zeichner, L.1
Rex, J.H.2
Pappas, P.G.3
Hamill, R.J.4
Larsen, R.A.5
Horowitz, H.W.6
Powderly, W.G.7
Hyslop, N.8
Kauffman, C.A.9
Cleary, J.10
Mangino, J.E.11
-
15
-
-
33747055130
-
-
Pagano L, Caira M, Candoni A, Offidani M, Fianchi L, Martino B, Pastore D, Picardi M, Bonini A, Chierichini A, Fanci R et al: The epidemiology of fungal infections in patients with hematologic malignancies: The SEIFEM-2004 study. Haematologica (2006) 91(8):1068-1075. • A retrospective cohort study evaluating the incidence and outcome of invasive fungal infections between 1999 and 2003 in patients with hematological malignancies.
-
Pagano L, Caira M, Candoni A, Offidani M, Fianchi L, Martino B, Pastore D, Picardi M, Bonini A, Chierichini A, Fanci R et al: The epidemiology of fungal infections in patients with hematologic malignancies: The SEIFEM-2004 study. Haematologica (2006) 91(8):1068-1075. • A retrospective cohort study evaluating the incidence and outcome of invasive fungal infections between 1999 and 2003 in patients with hematological malignancies.
-
-
-
-
17
-
-
34447515219
-
A comparative evaluation of properties and clinical efficacy of the echinocandins
-
Kim R, Khachikian D, Reboli AC: A comparative evaluation of properties and clinical efficacy of the echinocandins. Expert Opin Pharmacother (2007) 8(10):1479-1492.
-
(2007)
Expert Opin Pharmacother
, vol.8
, Issue.10
, pp. 1479-1492
-
-
Kim, R.1
Khachikian, D.2
Reboli, A.C.3
-
18
-
-
34548413171
-
Micafungin sodium, the second of the echinocandin class of antifungals: Theory and practice
-
Vehreschild JJ, Cornely OA: Micafungin sodium, the second of the echinocandin class of antifungals: Theory and practice. Future Microbiol (2006) 1:161-170.
-
(2006)
Future Microbiol
, vol.1
, pp. 161-170
-
-
Vehreschild, J.J.1
Cornely, O.A.2
-
19
-
-
0035282477
-
Mortality and costs of acute renal failure associated with amphotericin B therapy
-
Bates DW, Su L, Yu DT, Chertow GM, Seger DL, Gomes DR, Dasbach EJ, Platt R: Mortality and costs of acute renal failure associated with amphotericin B therapy. Clin Infect Dis (2001) 32(5):686-693.
-
(2001)
Clin Infect Dis
, vol.32
, Issue.5
, pp. 686-693
-
-
Bates, D.W.1
Su, L.2
Yu, D.T.3
Chertow, G.M.4
Seger, D.L.5
Gomes, D.R.6
Dasbach, E.J.7
Platt, R.8
-
20
-
-
85121960997
-
-
Mishra NN, Prasad T, Sharma N, Payasi A, Prasad R, Gupta DK, Singh R: Pathogenicity and drug resistance in Candida albicans and other yeast species. A review. Acta Microbiol Immunol Hung (2007) 54(3):201-235.
-
Mishra NN, Prasad T, Sharma N, Payasi A, Prasad R, Gupta DK, Singh R: Pathogenicity and drug resistance in Candida albicans and other yeast species. A review. Acta Microbiol Immunol Hung (2007) 54(3):201-235.
-
-
-
-
21
-
-
34248379039
-
In vitro activities of isavuconazole and other antifungal agents against Candida bloodstream isolates
-
Seifert H, Aurbach U, Stefanik D, Cornely O: In vitro activities of isavuconazole and other antifungal agents against Candida bloodstream isolates. Antimicrob Agents Chemother (2007) 51(5):1818-1821.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, Issue.5
, pp. 1818-1821
-
-
Seifert, H.1
Aurbach, U.2
Stefanik, D.3
Cornely, O.4
-
22
-
-
30344449770
-
In vitro activity of a new triazole BAL-4815, the active component of BAL-8557 (the water-soluble prodrug), against Aspergillus spp
-
Warn PA, Sharp A, Denning DW: In vitro activity of a new triazole BAL-4815, the active component of BAL-8557 (the water-soluble prodrug), against Aspergillus spp. J Antimicrob Chemother (2006) 57(1):135-138.
-
(2006)
J Antimicrob Chemother
, vol.57
, Issue.1
, pp. 135-138
-
-
Warn, P.A.1
Sharp, A.2
Denning, D.W.3
-
23
-
-
29944445355
-
Multiple-dose pharmacokinetics and safety of the new antifungal triazole BAL-4815 after intravenous infusion and oral administration of its prodrug, BAL-8557, in healthy volunteers
-
Schmitt-Hoffmann A, Roos B, Maares J, Heep M, Spickerman J, Weidekamm E, Brown T, Roehrle M: Multiple-dose pharmacokinetics and safety of the new antifungal triazole BAL-4815 after intravenous infusion and oral administration of its prodrug, BAL-8557, in healthy volunteers. Antimicrob Agents Chemother (2006) 50(1):286-293.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, Issue.1
, pp. 286-293
-
-
Schmitt-Hoffmann, A.1
Roos, B.2
Maares, J.3
Heep, M.4
Spickerman, J.5
Weidekamm, E.6
Brown, T.7
Roehrle, M.8
-
24
-
-
29944441643
-
Single-ascending-dose pharmacokinetics and safety of the novel broad-spectrum antifungal triazole BAL-4815 after intravenous infusions (50, 100, and 200 mg) and oral administrations (100, 200, and 400 mg) of its prodrug, BAL-8557, in healthy volunteers
-
Schmitt-Hoffmann A, Roos B, Heep M, Schleimer M, Weidekamm E, Brown T, Roehrle M, Beglinger C: Single-ascending-dose pharmacokinetics and safety of the novel broad-spectrum antifungal triazole BAL-4815 after intravenous infusions (50, 100, and 200 mg) and oral administrations (100, 200, and 400 mg) of its prodrug, BAL-8557, in healthy volunteers. Antimicrob Agents Chemother (2006) 50(1):279-285.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, Issue.1
, pp. 279-285
-
-
Schmitt-Hoffmann, A.1
Roos, B.2
Heep, M.3
Schleimer, M.4
Weidekamm, E.5
Brown, T.6
Roehrle, M.7
Beglinger, C.8
-
25
-
-
48349145720
-
-
Viljoen JJ, Mitha I, Heep M, Ghannoum M: Efficacy, safety, and tolerability of three different dosing regimens of BAL-8557 vs fluconazole in a double-blind, randomized, multicenter trial for the treatment of esophageal candidiasis in immunocompromised adults. ICAAC (2005) 45:Abs LB2-32.
-
Viljoen JJ, Mitha I, Heep M, Ghannoum M: Efficacy, safety, and tolerability of three different dosing regimens of BAL-8557 vs fluconazole in a double-blind, randomized, multicenter trial for the treatment of esophageal candidiasis in immunocompromised adults. ICAAC (2005) 45:Abs LB2-32.
-
-
-
-
26
-
-
48349096234
-
Basilea's antifungal meets phase II candidiasis endpoint
-
September 08
-
Pharmaceutica AG: Basilea's antifungal meets phase II candidiasis endpoint. Press Release (2005): September 08.
-
(2005)
Press Release
-
-
Pharmaceutica, A.G.1
-
27
-
-
33747873937
-
-
Ceftobiprole medocaril: BAL-5788, JNJ-30982081, JNJ-30982081, RO-65-5788, RO-655788. Drugs R D (2006) 7(5):305-311.
-
Ceftobiprole medocaril: BAL-5788, JNJ-30982081, JNJ-30982081, RO-65-5788, RO-655788. Drugs R D (2006) 7(5):305-311.
-
-
-
-
28
-
-
24344466955
-
β-Lactams against methicillin-resistant Staphylococcus aureus
-
Guignard B, Entenza JM, Moreillon P: β-Lactams against methicillin-resistant Staphylococcus aureus. Curr Opin Pharmacol (2005) 5(5):479-489.
-
(2005)
Curr Opin Pharmacol
, vol.5
, Issue.5
, pp. 479-489
-
-
Guignard, B.1
Entenza, J.M.2
Moreillon, P.3
-
29
-
-
33748575602
-
Anti-MRSA β -lactams in development
-
Page MG: Anti-MRSA β -lactams in development. Curr Opin Pharmacol (2006) 6(5):480-485.
-
(2006)
Curr Opin Pharmacol
, vol.6
, Issue.5
, pp. 480-485
-
-
Page, M.G.1
-
30
-
-
39749117473
-
A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections
-
Noel GJ, Bush K, Bagchi P, Ianus J, Strauss RS: A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections. Clin Infect Dis (2008) 46(5):647-55.
-
(2008)
Clin Infect Dis
, vol.46
, Issue.5
, pp. 647-655
-
-
Noel, G.J.1
Bush, K.2
Bagchi, P.3
Ianus, J.4
Strauss, R.S.5
-
31
-
-
37849009009
-
Results of a double-blind, randomized trial of ceftobiprole treatment of complicated skin and skin structure infections caused by Gram-positive bacteria
-
Noel GJ, Strauss RS, Amsler K, Heep M, Pypstra R, Solomkin JS: Results of a double-blind, randomized trial of ceftobiprole treatment of complicated skin and skin structure infections caused by Gram-positive bacteria. Antimicrob Agents Chemother (2008) 52(1):37-44.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, Issue.1
, pp. 37-44
-
-
Noel, G.J.1
Strauss, R.S.2
Amsler, K.3
Heep, M.4
Pypstra, R.5
Solomkin, J.S.6
-
32
-
-
36649004268
-
New antimicrobial agents as therapy for resistant Gram-positive cocci
-
An extended review on licensed and experimental antibiotics with activity against vancomycin-resistant and methicillin-resistant Gram-positive cocci, •
-
Lentino JR, Narita M, Yu VL: New antimicrobial agents as therapy for resistant Gram-positive cocci. Eur J Clin Microbiol Infect Dis (2008) 27(1):03-15. • An extended review on licensed and experimental antibiotics with activity against vancomycin-resistant and methicillin-resistant Gram-positive cocci.
-
(2008)
Eur J Clin Microbiol Infect Dis
, vol.27
, Issue.1
, pp. 03-15
-
-
Lentino, J.R.1
Narita, M.2
Yu, V.L.3
-
33
-
-
33645726430
-
Oritavancin - an investigational glycopeptide antibiotic
-
An evaluation of the antimicrobial activity, mechanism of action, pharmacodynamics, pharmacokinetics and safety of oritavancin, •
-
Ward KE, Mersfelder TL, LaPlante KL: Oritavancin - an investigational glycopeptide antibiotic. Expert Opin Investig Drugs (2006) 15(4):417-429. • An evaluation of the antimicrobial activity, mechanism of action, pharmacodynamics, pharmacokinetics and safety of oritavancin.
-
(2006)
Expert Opin Investig Drugs
, vol.15
, Issue.4
, pp. 417-429
-
-
Ward, K.E.1
Mersfelder, T.L.2
LaPlante, K.L.3
-
34
-
-
0037266399
-
Mechanism of action of oritavancin and related glycopeptide antibiotics
-
Allen NE, Nicas TI: Mechanism of action of oritavancin and related glycopeptide antibiotics. FEMS Microbiol Rev (2003) 26(5):511-532.
-
(2003)
FEMS Microbiol Rev
, vol.26
, Issue.5
, pp. 511-532
-
-
Allen, N.E.1
Nicas, T.I.2
-
35
-
-
5044238495
-
Pharmacokinetics, safety, and tolerability of ascending single intravenous doses of oritavancin administered to healthy human subjects
-
Bhavnani SM, Owen JS, Loutit JS, Porter SB, Ambrose PG: Pharmacokinetics, safety, and tolerability of ascending single intravenous doses of oritavancin administered to healthy human subjects. Diagn Microbiol Infect Dis (2004) 50(2):95-102.
-
(2004)
Diagn Microbiol Infect Dis
, vol.50
, Issue.2
, pp. 95-102
-
-
Bhavnani, S.M.1
Owen, J.S.2
Loutit, J.S.3
Porter, S.B.4
Ambrose, P.G.5
-
36
-
-
0038334898
-
Pharmacodynamics of oritavancin (LY-333328) in a neutropenic-mouse thigh model of Staphylococcus aureus infection
-
Boylan CJ, Campanale K, Iversen PW, Phillips DL, Zeckel ML, Parr TR Jr: Pharmacodynamics of oritavancin (LY-333328) in a neutropenic-mouse thigh model of Staphylococcus aureus infection. Antimicrob Agents Chemother (2003) 47(5):1700-1706.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, Issue.5
, pp. 1700-1706
-
-
Boylan, C.J.1
Campanale, K.2
Iversen, P.W.3
Phillips, D.L.4
Zeckel, M.L.5
Parr Jr, T.R.6
-
37
-
-
33644638214
-
Pharmacokinetic-pharmacodynamic relationships describing the efficacy of oritavancin in patients with Staphylococcus aureus bacteremia
-
Bhavnani SM, Passarell JA, Owen JS, Loutit JS, Porter SB, Ambrose PG: Pharmacokinetic-pharmacodynamic relationships describing the efficacy of oritavancin in patients with Staphylococcus aureus bacteremia. Antimicrob Agents Chemother (2006) 50(3):994-1000.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, Issue.3
, pp. 994-1000
-
-
Bhavnani, S.M.1
Passarell, J.A.2
Owen, J.S.3
Loutit, J.S.4
Porter, S.B.5
Ambrose, P.G.6
-
38
-
-
48349086941
-
-
Wasilewski M, Disch DP, McGill JM, Harris HW, O'Riordan W, Zeckel ML: Equivalence of shorter course therapy with oritavancin vs vancomycin cephalexin in complicated skin/skin structure infections. ICAAC (2001) 41: Abs UL-18.
-
Wasilewski M, Disch DP, McGill JM, Harris HW, O'Riordan W, Zeckel ML: Equivalence of shorter course therapy with oritavancin vs vancomycin cephalexin in complicated skin/skin structure infections. ICAAC (2001) 41: Abs UL-18.
-
-
-
-
39
-
-
48349102851
-
-
InterMune Inc: InterMune presents oritavancin data at 43rd Interscience Conference On Antimicrobial Agents and Chemotherapy. Press Release (2003): September 13.
-
InterMune Inc: InterMune presents oritavancin data at 43rd Interscience Conference On Antimicrobial Agents and Chemotherapy. Press Release (2003): September 13.
-
-
-
-
40
-
-
48349140572
-
-
Targanta Therapeutics, Quebec, Canada , June 10
-
Pipeline-Oritavancin program: Targanta Therapeutics, Quebec, Canada (2008): June 10. http://www.targanta.com/pipeline/oritavancin.html.
-
(2008)
Pipeline-Oritavancin program
-
-
-
41
-
-
15844426950
-
Origin, structure, and activity in vitro and in vivo of dalbavancin
-
Malabarba A, Goldstein BP: Origin, structure, and activity in vitro and in vivo of dalbavancin. J Antimicrob Chemother (2005) 55(Suppl 2):ii15-ii20.
-
(2005)
J Antimicrob Chemother
, vol.55
, Issue.SUPPL. 2
-
-
Malabarba, A.1
Goldstein, B.P.2
-
42
-
-
0036231609
-
Dalbavancin (Biosearch Italia/Versicor)
-
Steiert M, Schmitz FJ: Dalbavancin (Biosearch Italia/Versicor). Curr Opin Investig Drugs (2002) 3(2):229-233.
-
(2002)
Curr Opin Investig Drugs
, vol.3
, Issue.2
, pp. 229-233
-
-
Steiert, M.1
Schmitz, F.J.2
-
43
-
-
14844339524
-
Glycopeptide and lipoglycopeptide antibiotics
-
Kahne D, Leimkuhler C, Lu W, Walsh C: Glycopeptide and lipoglycopeptide antibiotics. Chem Rev (2005) 105(2):425-448.
-
(2005)
Chem Rev
, vol.105
, Issue.2
, pp. 425-448
-
-
Kahne, D.1
Leimkuhler, C.2
Lu, W.3
Walsh, C.4
-
44
-
-
29144496043
-
Dalbavancin activity against selected populations of antimicrobial-resistant Gram-positive pathogens
-
Streit JM, Sader HS, Fritsche TR, Jones RN: Dalbavancin activity against selected populations of antimicrobial-resistant Gram-positive pathogens. Diagn Microbiol Infect Dis (2005) 53(4):307-310.
-
(2005)
Diagn Microbiol Infect Dis
, vol.53
, Issue.4
, pp. 307-310
-
-
Streit, J.M.1
Sader, H.S.2
Fritsche, T.R.3
Jones, R.N.4
-
45
-
-
1242270459
-
Worldwide assessment of dalbavancin activity and spectrum against over 6,000 clinical isolates
-
In this study, dalbavancin and more than 20 comparator agents were tested against 6,339 clinical isolates from the US and Europe, with the drug exhibiting superior activity, •
-
Streit JM, Fritsche TR, Sader HS, Jones RN: Worldwide assessment of dalbavancin activity and spectrum against over 6,000 clinical isolates. Diagn Microbiol Infect Dis (2004) 48(2):137-143. • In this study, dalbavancin and more than 20 comparator agents were tested against 6,339 clinical isolates from the US and Europe, with the drug exhibiting superior activity.
-
(2004)
Diagn Microbiol Infect Dis
, vol.48
, Issue.2
, pp. 137-143
-
-
Streit, J.M.1
Fritsche, T.R.2
Sader, H.S.3
Jones, R.N.4
-
46
-
-
48349138781
-
-
Andes DR, Craig WA: In vivo pharmacodynamic characterization of dalbavancin in the murine thigh infection model. ICAAC (2004) 44: Abs 1872.
-
Andes DR, Craig WA: In vivo pharmacodynamic characterization of dalbavancin in the murine thigh infection model. ICAAC (2004) 44: Abs 1872.
-
-
-
-
47
-
-
1442349121
-
Tolerability, pharmacokinetics, and serum bactericidal activity of intravenous dalbavancin in healthy volunteers
-
Leighton A, Gottlieb AB, Dorr MB, Jabes D, Mosconi G, VanSaders C, Mroszczak EJ, Campbell KC, Kelly E: Tolerability, pharmacokinetics, and serum bactericidal activity of intravenous dalbavancin in healthy volunteers. Antimicrob Agents Chemother (2004) 48(3):940-945.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, Issue.3
, pp. 940-945
-
-
Leighton, A.1
Gottlieb, A.B.2
Dorr, M.B.3
Jabes, D.4
Mosconi, G.5
VanSaders, C.6
Mroszczak, E.J.7
Campbell, K.C.8
Kelly, E.9
-
48
-
-
48349131208
-
-
Seltzer E, Goldberg L, Krause D: Safety of dalbavancin in a clinical development program. ICAAC (2005) 45: Abs L1576.
-
Seltzer E, Goldberg L, Krause D: Safety of dalbavancin in a clinical development program. ICAAC (2005) 45: Abs L1576.
-
-
-
-
49
-
-
0242468561
-
Once-weekly dalbavancin versus standard-of-care antimicrobial regimens for treatment of skin and soft-tissue infections
-
Seltzer E, Dorr MB, Goldstein BP, Perry M, Dowell JA, Henkel T: Once-weekly dalbavancin versus standard-of-care antimicrobial regimens for treatment of skin and soft-tissue infections. Clin Infect Dis (2003) 37(10):1298-1303.
-
(2003)
Clin Infect Dis
, vol.37
, Issue.10
, pp. 1298-1303
-
-
Seltzer, E.1
Dorr, M.B.2
Goldstein, B.P.3
Perry, M.4
Dowell, J.A.5
Henkel, T.6
-
50
-
-
48349091120
-
-
Goldstein BP, Seltzer E, Flamm R, Sahm D: Dalbavancin phase III skin and skin structure studies: Pathogens and microbiological efficacy. ICAAC (2005) 45: Abs L1577.
-
Goldstein BP, Seltzer E, Flamm R, Sahm D: Dalbavancin phase III skin and skin structure studies: Pathogens and microbiological efficacy. ICAAC (2005) 45: Abs L1577.
-
-
-
-
51
-
-
27644549908
-
Randomized, double-blind comparison of once-weekly dalbavancin versus twice-daily linezolid therapy for the treatment of complicated skin and skin structure infections
-
Jauregui LE, Babazadeh S, Seltzer E, Goldberg L, Krievins D, Frederick M, Krause D, Satilovs I, Endzinas Z, Breaux J, O'Riordan W: Randomized, double-blind comparison of once-weekly dalbavancin versus twice-daily linezolid therapy for the treatment of complicated skin and skin structure infections. Clin Infect Dis (2005) 41(10):1407-1415.
-
(2005)
Clin Infect Dis
, vol.41
, Issue.10
, pp. 1407-1415
-
-
Jauregui, L.E.1
Babazadeh, S.2
Seltzer, E.3
Goldberg, L.4
Krievins, D.5
Frederick, M.6
Krause, D.7
Satilovs, I.8
Endzinas, Z.9
Breaux, J.10
O'Riordan, W.11
-
52
-
-
13444257356
-
Efficacy and safety of weekly dalbavancin therapy for catheter-related bloodstream infection caused by Gram-positive pathogens
-
Raad I, Darouiche R, Vazquez J, Lentnek A, Hachem R, Hanna H, Goldstein B, Henkel T, Seltzer E: Efficacy and safety of weekly dalbavancin therapy for catheter-related bloodstream infection caused by Gram-positive pathogens. Clin Infect Dis (2005) 40(3):374-380.
-
(2005)
Clin Infect Dis
, vol.40
, Issue.3
, pp. 374-380
-
-
Raad, I.1
Darouiche, R.2
Vazquez, J.3
Lentnek, A.4
Hachem, R.5
Hanna, H.6
Goldstein, B.7
Henkel, T.8
Seltzer, E.9
-
53
-
-
33947174540
-
-
Pfizer Inc: Pfizer receives approvable letter from FDA for dalbavancin, December 21
-
Pfizer Inc: Pfizer receives approvable letter from FDA for dalbavancin. Press Release (2007): December 21.
-
(2007)
Press Release
-
-
-
54
-
-
20044363986
-
Telavancin, a multifunctional lipoglycopeptide, disrupts both cell wall synthesis and cell membrane integrity in methicillin-resistant Staphylococcus aureus
-
Higgins DL, Chang R, Debabov DV, Leung J, Wu T, Krause KM, Sandvik E, Hubbard JM, Kaniga K, Schmidt DE Jr, Gao Q et al: Telavancin, a multifunctional lipoglycopeptide, disrupts both cell wall synthesis and cell membrane integrity in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2005) 49(3):1127-1134.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, Issue.3
, pp. 1127-1134
-
-
Higgins, D.L.1
Chang, R.2
Debabov, D.V.3
Leung, J.4
Wu, T.5
Krause, K.M.6
Sandvik, E.7
Hubbard, J.M.8
Kaniga, K.9
Schmidt Jr, D.E.10
Gao, Q.11
-
55
-
-
33748089329
-
Comparative activity of the new lipoglycopeptide telavancin in the presence and absence of serum against 50 glycopeptide non-susceptible staphylococci and three vancomycin-resistant Staphylococcus aureus
-
Leuthner KD, Cheung CM, Rybak MJ: Comparative activity of the new lipoglycopeptide telavancin in the presence and absence of serum against 50 glycopeptide non-susceptible staphylococci and three vancomycin-resistant Staphylococcus aureus. J Antimicrob Chemother (2006) 58(2):338-343.
-
(2006)
J Antimicrob Chemother
, vol.58
, Issue.2
, pp. 338-343
-
-
Leuthner, K.D.1
Cheung, C.M.2
Rybak, M.J.3
-
56
-
-
11244316714
-
Pharmacokinetics, serum inhibitory and bactericidal activity, and safety of telavancin in healthy subjects
-
Shaw JP, Seroogy J, Kaniga K, Higgins DL, Kitt M, Barriere S: Pharmacokinetics, serum inhibitory and bactericidal activity, and safety of telavancin in healthy subjects. Antimicrob Agents Chemother (2005) 49(1):195-201.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, Issue.1
, pp. 195-201
-
-
Shaw, J.P.1
Seroogy, J.2
Kaniga, K.3
Higgins, D.L.4
Kitt, M.5
Barriere, S.6
-
57
-
-
33947174540
-
-
Theravance Inc: Theravance receives FDA approvable letter for telavancin for the treatment of complicated skin and skin structure infections, October 21
-
Theravance Inc: Theravance receives FDA approvable letter for telavancin for the treatment of complicated skin and skin structure infections. Press Release (2007): October 21.
-
(2007)
Press Release
-
-
-
58
-
-
48349092500
-
-
NCT00062647: Telavancin (TD 6424, ARBELIC™) for treatment of uncomplicated Staphylococcus aureus bacteremia. NIH, Bethesda, MD, USA (2006). http://clinicaltrials.gov/ct2/show/NCT00062647? term=NCT00062647&rank=1.
-
NCT00062647: Telavancin (TD 6424, ARBELIC™) for treatment of uncomplicated Staphylococcus aureus bacteremia. NIH, Bethesda, MD, USA (2006). http://clinicaltrials.gov/ct2/show/NCT00062647? term=NCT00062647&rank=1.
-
-
-
-
59
-
-
17644389620
-
Colistin: The revival of polymyxins for the management of multidrug-resistant Gram-negative bacterial infections
-
A useful review on the chemistry/structure, mechanism of action, pharmacokinetic/pharmacodynamic properties, spectrum of activity, adverse effects, in vitro susceptibility of various pathogens, and clinical use of colistin, •
-
Falagas ME, Kasiakou SK: Colistin: The revival of polymyxins for the management of multidrug-resistant Gram-negative bacterial infections. Clin Infect Dis (2005) 40(9):1333-1341. • A useful review on the chemistry/structure, mechanism of action, pharmacokinetic/pharmacodynamic properties, spectrum of activity, adverse effects, in vitro susceptibility of various pathogens, and clinical use of colistin.
-
(2005)
Clin Infect Dis
, vol.40
, Issue.9
, pp. 1333-1341
-
-
Falagas, M.E.1
Kasiakou, S.K.2
-
60
-
-
35349022577
-
Polymyxin B: Similarities to and differences from colistin (polymyxin E)
-
Kwa A, Kasiakou SK, Tam VH, Falagas ME: Polymyxin B: Similarities to and differences from colistin (polymyxin E). Expert Rev Anti Infect Ther (2007) 5(5):811-821.
-
(2007)
Expert Rev Anti Infect Ther
, vol.5
, Issue.5
, pp. 811-821
-
-
Kwa, A.1
Kasiakou, S.K.2
Tam, V.H.3
Falagas, M.E.4
-
61
-
-
34447560960
-
Toxicity of polymyxins: A systematic review of the evidence from old and recent studies
-
Falagas ME, Kasiakou SK: Toxicity of polymyxins: A systematic review of the evidence from old and recent studies. Crit Care (2006) 10(1):R27.
-
(2006)
Crit Care
, vol.10
, Issue.1
-
-
Falagas, M.E.1
Kasiakou, S.K.2
-
62
-
-
27744466462
-
Nephrotoxicity of intravenous colistin: A prospective evaluation
-
Falagas ME, Fragoulis KN, Kasiakou SK, Sermaidis GJ, Michalopoulos A: Nephrotoxicity of intravenous colistin: A prospective evaluation. Int J Antimicrob Agents (2005) 26(6):504-507.
-
(2005)
Int J Antimicrob Agents
, vol.26
, Issue.6
, pp. 504-507
-
-
Falagas, M.E.1
Fragoulis, K.N.2
Kasiakou, S.K.3
Sermaidis, G.J.4
Michalopoulos, A.5
-
63
-
-
17644362912
-
Toxicity after prolonged (more than four weeks) administration of intravenous colistin
-
Falagas ME, Rizos M, Bliziotis IA, Rellos K, Kasiakou SK, Michalopoulos A: Toxicity after prolonged (more than four weeks) administration of intravenous colistin. BMC Infect Dis (2005) 5(1):1.
-
(2005)
BMC Infect Dis
, vol.5
, Issue.1
, pp. 1
-
-
Falagas, M.E.1
Rizos, M.2
Bliziotis, I.A.3
Rellos, K.4
Kasiakou, S.K.5
Michalopoulos, A.6
-
64
-
-
0037378043
-
Stability of colistin and colistin methanesulfonate in aqueous media and plasma as determined by high-performance liquid chromatography
-
Li J, Milne RW, Nation RL, Turnidge JD, Coulthard K: Stability of colistin and colistin methanesulfonate in aqueous media and plasma as determined by high-performance liquid chromatography. Antimicrob Agents Chemother (2003) 47(4):1364-1370.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, Issue.4
, pp. 1364-1370
-
-
Li, J.1
Milne, R.W.2
Nation, R.L.3
Turnidge, J.D.4
Coulthard, K.5
-
65
-
-
0348149151
-
Steady-state pharmacokinetics of intravenous colistin methanesulphonate in patients with cystic fibrosis
-
Li J, Coulthard K, Milne R, Nation RL, Conway S, Peckham D, Etherington C, Turnidge J: Steady-state pharmacokinetics of intravenous colistin methanesulphonate in patients with cystic fibrosis. J Antimicrob Chemother (2003) 52(6):987-992.
-
(2003)
J Antimicrob Chemother
, vol.52
, Issue.6
, pp. 987-992
-
-
Li, J.1
Coulthard, K.2
Milne, R.3
Nation, R.L.4
Conway, S.5
Peckham, D.6
Etherington, C.7
Turnidge, J.8
-
66
-
-
23044515861
-
Combination therapy with intravenous colistin for management of infections due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis
-
Kasiakou SK, Michalopoulos A, Soteriades ES, Samonis G, Sermaides GJ, Falagas ME: Combination therapy with intravenous colistin for management of infections due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis. Antimicrob Agents Chemother (2005) 49(8):3136-3146.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, Issue.8
, pp. 3136-3146
-
-
Kasiakou, S.K.1
Michalopoulos, A.2
Soteriades, E.S.3
Samonis, G.4
Sermaides, G.J.5
Falagas, M.E.6
-
67
-
-
84991212329
-
Intravenous colistin in the treatment of sepsis from multiresistant Gram-negative bacilli in critically ill patients
-
Markou N, Apostolakos H, Koumoudiou C, Athanasiou M, Koutsoukou A, Alamanos I, Gregorakos L: Intravenous colistin in the treatment of sepsis from multiresistant Gram-negative bacilli in critically ill patients. Crit Care (2003) 7(5):R78-R83.
-
(2003)
Crit Care
, vol.7
, Issue.5
-
-
Markou, N.1
Apostolakos, H.2
Koumoudiou, C.3
Athanasiou, M.4
Koutsoukou, A.5
Alamanos, I.6
Gregorakos, L.7
-
68
-
-
48349139860
-
-
NCT00300560: Efficacy and safety of colistin for therapy of infections caused by ESBL-producing K pneumoniae or E coli. NIH, Bethesda, MD, USA (2006). http://clinicaltrials.gov/ct2/show/ NCT00300560?term=NCT00300560&rank=1.
-
NCT00300560: Efficacy and safety of colistin for therapy of infections caused by ESBL-producing K pneumoniae or E coli. NIH, Bethesda, MD, USA (2006). http://clinicaltrials.gov/ct2/show/ NCT00300560?term=NCT00300560&rank=1.
-
-
-
-
69
-
-
0242569143
-
Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria
-
Schneider P, Hawser S, Islam K. Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorg Med Chem Lett (2003) 13(23):4217-4221.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, Issue.23
, pp. 4217-4221
-
-
Schneider, P.1
Hawser, S.2
Islam, K.3
-
70
-
-
33947174540
-
-
Arpida Ltd: Arpida completes enrolment in phase III trial with intravenous iclaprim, March 22
-
Arpida Ltd: Arpida completes enrolment in phase III trial with intravenous iclaprim. Press Release (2007): March 22.
-
(2007)
Press Release
-
-
-
71
-
-
48349146208
-
Arpida receives approval from US FDA to initiate a phase II trial with iclaprim in hospital-acquired, ventilator and healthcare- associated pneumonia
-
Arpida Ltd:, June 21
-
Arpida Ltd: Arpida receives approval from US FDA to initiate a phase II trial with iclaprim in hospital-acquired, ventilator and healthcare- associated pneumonia. Press Release (2007): June 21.
-
(2007)
Press Release
-
-
-
72
-
-
38849190721
-
Iclaprim, a diaminopyrimidine dihydrofolate reductase inhibitor for the potential treatment of antibiotic-resistant staphylococcal infections
-
Peppard WJ, Schuenke CD. Iclaprim, a diaminopyrimidine dihydrofolate reductase inhibitor for the potential treatment of antibiotic-resistant staphylococcal infections. Curr Opin Investig Drugs (2008) 9(2):210-225.
-
(2008)
Curr Opin Investig Drugs
, vol.9
, Issue.2
, pp. 210-225
-
-
Peppard, W.J.1
Schuenke, C.D.2
-
73
-
-
34548553297
-
-
Kohlhoff SA, Sharma R. Iclaprim. Expert Opin Investig Drugs (2007) 16(9):1441-1448.
-
Kohlhoff SA, Sharma R. Iclaprim. Expert Opin Investig Drugs (2007) 16(9):1441-1448.
-
-
-
-
74
-
-
9644287934
-
The synthetic N-terminal peptide of human lactoferrin, hLF 1-11, is highly effective against experimental infection caused by multidrug-resistant Acinetobacter baumannii
-
Dijkshoorn L, Brouwer CP, Bogaards SJ, Nemec A, van den Broek PJ, Nibbering PH: The synthetic N-terminal peptide of human lactoferrin, hLF 1-11, is highly effective against experimental infection caused by multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother (2004) 48(12):4919-4921.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, Issue.12
, pp. 4919-4921
-
-
Dijkshoorn, L.1
Brouwer, C.P.2
Bogaards, S.J.3
Nemec, A.4
van den Broek, P.J.5
Nibbering, P.H.6
-
75
-
-
0037228719
-
Synergistic activity of the N-terminal peptide of human lactoferrin and fluconazole against Candida species
-
Lupetti A, Paulusma-Annema A, Welling MM, Dogterom-Ballering H, Brouwer CP, Senesi S, Van Dissel JT, Nibbering PH: Synergistic activity of the N-terminal peptide of human lactoferrin and fluconazole against Candida species. Antimicrob Agents Chemother (2003) 47(1):262-267.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, Issue.1
, pp. 262-267
-
-
Lupetti, A.1
Paulusma-Annema, A.2
Welling, M.M.3
Dogterom-Ballering, H.4
Brouwer, C.P.5
Senesi, S.6
Van Dissel, J.T.7
Nibbering, P.H.8
-
76
-
-
27944438079
-
Histatin- and lactoferrin-derived peptides: Antimicrobial properties and effects on mammalian cells
-
Stallmann HP, Faber C, Bronckers AL, de Blieck-Hogervorst JM, Brouwer CP, Amerongen AV, Wuisman PI: Histatin- and lactoferrin-derived peptides: Antimicrobial properties and effects on mammalian cells. Peptides (2005) 26(12):2355-2359.
-
(2005)
Peptides
, vol.26
, Issue.12
, pp. 2355-2359
-
-
Stallmann, H.P.1
Faber, C.2
Bronckers, A.L.3
de Blieck-Hogervorst, J.M.4
Brouwer, C.P.5
Amerongen, A.V.6
Wuisman, P.I.7
-
77
-
-
0343288991
-
Lactoferrin regulates the immune responses in post-surgical patients
-
Zimecki M, Wlaszczyk A, Wojciechowski R, Dawiskiba J, Kruzel M: Lactoferrin regulates the immune responses in post-surgical patients. Arch Immunol Ther Exp (Warsz) (2001) 49(4):325-333.
-
(2001)
Arch Immunol Ther Exp (Warsz)
, vol.49
, Issue.4
, pp. 325-333
-
-
Zimecki, M.1
Wlaszczyk, A.2
Wojciechowski, R.3
Dawiskiba, J.4
Kruzel, M.5
-
78
-
-
48349096908
-
Dutch biopharmaceutical company AM-Pharma strengthens intellectual property position for lactoferrin-derived antimicrobial peptide hLF 1-11
-
August 10
-
AM-Pharma BV: Dutch biopharmaceutical company AM-Pharma strengthens intellectual property position for lactoferrin-derived antimicrobial peptide hLF 1-11. Press Release (2006): August 10.
-
(2006)
Press Release
-
-
AM-Pharma, B.V.1
-
79
-
-
25444462811
-
Outcome of infections due to pandrug-resistant (PDR) Gram-negative bacteria
-
Falagas ME, Bliziotis IA, Kasiakou SK, Samonis G, Athanassopoulou P, Michalopoulos A: Outcome of infections due to pandrug-resistant (PDR) Gram-negative bacteria. BMC Infect Dis (2005) 5(1):24.
-
(2005)
BMC Infect Dis
, vol.5
, Issue.1
, pp. 24
-
-
Falagas, M.E.1
Bliziotis, I.A.2
Kasiakou, S.K.3
Samonis, G.4
Athanassopoulou, P.5
Michalopoulos, A.6
-
80
-
-
35548970654
-
A comparative study on the cost of new antibiotics and drugs of other therapeutic categories
-
Falagas ME, Fragoulis KN, Karydis I: A comparative study on the cost of new antibiotics and drugs of other therapeutic categories. PLoS ONE (2006) 20(1):e11.
-
(2006)
PLoS ONE
, vol.20
, Issue.1
-
-
Falagas, M.E.1
Fragoulis, K.N.2
Karydis, I.3
|