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Volumn 24, Issue 4, 2008, Pages 385-391

Passive and oxymetazoline-enhanced delivery with a lens device: Pharmacokinetics and efficacy studies with rabbits

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE SODIUM PHOSPHATE; OXYMETAZOLINE; SILICONE;

EID: 48349100977     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2007.0116     Document Type: Article
Times cited : (9)

References (42)
  • 1
    • 0035980321 scopus 로고    scopus 로고
    • Transscleral drug delivery for posterior segment disease
    • Geroski, D.H., and Edelhauser, H.F. Transscleral drug delivery for posterior segment disease. Adv. Drug Deliv. Rev. 52:37-48, 2001.
    • (2001) Adv. Drug Deliv. Rev , vol.52 , pp. 37-48
    • Geroski, D.H.1    Edelhauser, H.F.2
  • 2
    • 0022852854 scopus 로고
    • Topical ocular drug delivery: Recent developments and future challenges
    • Lee, V.H., and Robinson, J.R. Topical ocular drug delivery: Recent developments and future challenges. J. Ocul. Pharmacol. Ther. 2:67-108, 1986.
    • (1986) J. Ocul. Pharmacol. Ther , vol.2 , pp. 67-108
    • Lee, V.H.1    Robinson, J.R.2
  • 3
    • 0034045780 scopus 로고    scopus 로고
    • Biopharmaceutical considerations in topical ocular drug delivery
    • Davies, N.M. Biopharmaceutical considerations in topical ocular drug delivery. Clin. Exp. Pharmacol. Physiol. 27: 558-562, 2000.
    • (2000) Clin. Exp. Pharmacol. Physiol , vol.27 , pp. 558-562
    • Davies, N.M.1
  • 4
    • 0024415136 scopus 로고
    • Collagen shield enhancement of topical dexamethasone penetration
    • Hwang, D.G., Stern, W.H., Hwang, P.H., et al. Collagen shield enhancement of topical dexamethasone penetration. Arch. Ophthalmol. 107:1375-1380, 1989.
    • (1989) Arch. Ophthalmol , vol.107 , pp. 1375-1380
    • Hwang, D.G.1    Stern, W.H.2    Hwang, P.H.3
  • 5
    • 0036117863 scopus 로고    scopus 로고
    • Cyclodextrins in eye drop formulations: Enhanced topical delivery of corticosteroids to the eye
    • Loftsson, T., and Stefansson, E. Cyclodextrins in eye drop formulations: Enhanced topical delivery of corticosteroids to the eye. Acta. Ophthalmol. Scand. 80:144-150, 2002.
    • (2002) Acta. Ophthalmol. Scand , vol.80 , pp. 144-150
    • Loftsson, T.1    Stefansson, E.2
  • 6
    • 18744409539 scopus 로고    scopus 로고
    • Colloidal carriers for ophthalmic drug delivery
    • Mainardes, R.M., Urban, M.C., Cinto, P.O., et al. Colloidal carriers for ophthalmic drug delivery. Curr. Drug Targ. 6:363-371, 2005.
    • (2005) Curr. Drug Targ , vol.6 , pp. 363-371
    • Mainardes, R.M.1    Urban, M.C.2    Cinto, P.O.3
  • 8
    • 1042277993 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye II: Development and validation of a simple pharmacokinetic model for subconjunctival injection
    • Lee, T.W., and Robinson, J.R. Drug delivery to the posterior segment of the eye II: Development and validation of a simple pharmacokinetic model for subconjunctival injection. J. Ocul. Pharmacol. Ther. 20:43-53, 2004.
    • (2004) J. Ocul. Pharmacol. Ther , vol.20 , pp. 43-53
    • Lee, T.W.1    Robinson, J.R.2
  • 9
    • 31344468895 scopus 로고    scopus 로고
    • A rabbit model for assessing the ocular barriers to the trans-scleral delivery of triamcinolone acetonide
    • Robinson, M.R., Lee, S.S., Kim, H., et al. A rabbit model for assessing the ocular barriers to the trans-scleral delivery of triamcinolone acetonide. Exp. Eye Res. 82:479-487, 2006.
    • (2006) Exp. Eye Res , vol.82 , pp. 479-487
    • Robinson, M.R.1    Lee, S.S.2    Kim, H.3
  • 10
    • 0027252620 scopus 로고
    • Minimizing systemic absorption of topically administered ophthalmic drugs
    • Urtti, A., and Salminen, L. Minimizing systemic absorption of topically administered ophthalmic drugs. Surv. Ophthalmol. 37:435-456, 1993.
    • (1993) Surv. Ophthalmol , vol.37 , pp. 435-456
    • Urtti, A.1    Salminen, L.2
  • 11
    • 0035980366 scopus 로고    scopus 로고
    • Preface: Drug delivery to the posterior segment of the eye
    • Ogura, Y. Preface: Drug delivery to the posterior segment of the eye. Adv. Drug Deliv. Rev. 52:1-3, 2001.
    • (2001) Adv. Drug Deliv. Rev , vol.52 , pp. 1-3
    • Ogura, Y.1
  • 12
    • 0024421694 scopus 로고
    • Trans-scleral ion-tophoresis of dexamethasone
    • Lam, T.T., Edward, D.P., Zhu, X.A., et al. Trans-scleral ion-tophoresis of dexamethasone. Arch. Ophthalmol. 107:1368-1371, 1989.
    • (1989) Arch. Ophthalmol , vol.107 , pp. 1368-1371
    • Lam, T.T.1    Edward, D.P.2    Zhu, X.A.3
  • 13
    • 0026674626 scopus 로고
    • The blood-retinal barrier in experimental autoimmune uveoretinitis (EAU): A review
    • Greenwood, J. The blood-retinal barrier in experimental autoimmune uveoretinitis (EAU): A review. Curr. Eye Res. 11(Suppl):25-32, 1992.
    • (1992) Curr. Eye Res , vol.11 , Issue.SUPPL. , pp. 25-32
    • Greenwood, J.1
  • 14
    • 0028351891 scopus 로고
    • Steroidal and nonsteroidal drugs in endotoxin-induced uveitis
    • Kulkarni, P.S. Steroidal and nonsteroidal drugs in endotoxin-induced uveitis. J. Ocul. Pharmacol. Ther. 10:329-334, 1994.
    • (1994) J. Ocul. Pharmacol. Ther , vol.10 , pp. 329-334
    • Kulkarni, P.S.1
  • 15
    • 0030972026 scopus 로고    scopus 로고
    • Peribulbar corticosteroid injection: Vitreal and serum concentrations after dexamethasone disodium phosphate injection
    • Weijtens, O., van der Sluijs, F.A., Schoemaker, R.C., et al. Peribulbar corticosteroid injection: Vitreal and serum concentrations after dexamethasone disodium phosphate injection. Am. J. Ophthalmol. 123:358-363, 1997.
    • (1997) Am. J. Ophthalmol , vol.123 , pp. 358-363
    • Weijtens, O.1    van der Sluijs, F.A.2    Schoemaker, R.C.3
  • 16
    • 0025094153 scopus 로고
    • Improved ocular: Systemic absorption ratio of timolol by viscous vehicle and phenylephrine
    • Kyyronen, K., and Urtti, A. Improved ocular: Systemic absorption ratio of timolol by viscous vehicle and phenylephrine. Invest. Ophthalmol. Vis. Sci. 31:1827-1833, 1990.
    • (1990) Invest. Ophthalmol. Vis. Sci , vol.31 , pp. 1827-1833
    • Kyyronen, K.1    Urtti, A.2
  • 17
    • 48349147627 scopus 로고    scopus 로고
    • New treatment for eye disease reduces need for strong drugs
    • Stein, J., and Coogan, M. New treatment for eye disease reduces need for strong drugs. NEI Press Release, 1997.
    • (1997) NEI Press Release
    • Stein, J.1    Coogan, M.2
  • 19
    • 21444461055 scopus 로고    scopus 로고
    • Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis
    • Jaffe, G.J., McCallum, R.M., Branchaud, B., et al. Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis. Ophthalmology 112:1192-1198, 2005.
    • (2005) Ophthalmology , vol.112 , pp. 1192-1198
    • Jaffe, G.J.1    McCallum, R.M.2    Branchaud, B.3
  • 20
    • 0347531776 scopus 로고    scopus 로고
    • Effects of a new dexamethasone-delivery system (Surodex) on experimental intraocular inflammation models
    • Kodama, M., Numaga, J., Yoshida, A., et al. Effects of a new dexamethasone-delivery system (Surodex) on experimental intraocular inflammation models. Graefe's Arch. Clin. Exp. Ophthalmol. 241:927-933, 2003.
    • (2003) Graefe's Arch. Clin. Exp. Ophthalmol , vol.241 , pp. 927-933
    • Kodama, M.1    Numaga, J.2    Yoshida, A.3
  • 21
    • 0029561646 scopus 로고
    • Diclofenac and prednisolone inhibit endotoxin-induced uveitis in rabbits
    • Kulkarni, P.S., and Paterson, C.A. Diclofenac and prednisolone inhibit endotoxin-induced uveitis in rabbits. Exp. Eye Res. 61:767-768, 1995.
    • (1995) Exp. Eye Res , vol.61 , pp. 767-768
    • Kulkarni, P.S.1    Paterson, C.A.2
  • 22
    • 0027177256 scopus 로고
    • Intraocular dexamethasone penetration via subconjunctival or retrobulbar injections in rabbits
    • Bodker, F.S., Ticho, B.H., Feist, R.M., et al. Intraocular dexamethasone penetration via subconjunctival or retrobulbar injections in rabbits. Ophthalmic Surg. 24:453-457, 1993.
    • (1993) Ophthalmic Surg , vol.24 , pp. 453-457
    • Bodker, F.S.1    Ticho, B.H.2    Feist, R.M.3
  • 23
    • 0028814692 scopus 로고
    • Intravitreal sustained-release dexamethasone device in the treatment of experimental uveitis
    • Cheng, C.K., Berger, A.S., Pearson, P.A., et al. Intravitreal sustained-release dexamethasone device in the treatment of experimental uveitis. Invest. Ophthalmol. Vis. Sci. 36:442-453, 1995.
    • (1995) Invest. Ophthalmol. Vis. Sci , vol.36 , pp. 442-453
    • Cheng, C.K.1    Berger, A.S.2    Pearson, P.A.3
  • 24
    • 11444263514 scopus 로고    scopus 로고
    • New vehicle based on a microemulsion for topical ocular administration of dexamethasone
    • Fialho, S.L., and da Silva-Cunha, A. New vehicle based on a microemulsion for topical ocular administration of dexamethasone. Clin. Exp. Ophthalmol. 32:626-632, 2004.
    • (2004) Clin. Exp. Ophthalmol , vol.32 , pp. 626-632
    • Fialho, S.L.1    da Silva-Cunha, A.2
  • 25
    • 33750682050 scopus 로고    scopus 로고
    • The effect of recombinant human hyaluronidase on dexamethasone penetration into the posterior segment of the eye after sub-Tenon's injection
    • Kozak, I., Kayikcioglu, O.R., Cheng, L., et al. The effect of recombinant human hyaluronidase on dexamethasone penetration into the posterior segment of the eye after sub-Tenon's injection. J. Ocul. Pharmacol. Ther. 22:362-369, 2006.
    • (2006) J. Ocul. Pharmacol. Ther , vol.22 , pp. 362-369
    • Kozak, I.1    Kayikcioglu, O.R.2    Cheng, L.3
  • 26
    • 34447334610 scopus 로고    scopus 로고
    • Cyclodextrin microparticles for drug delivery to the posterior segment of the eye: Aqueous dexamethasone eye drops
    • Loftsson, T., Hreinsdottir, D., and Stefansson, E. Cyclodextrin microparticles for drug delivery to the posterior segment of the eye: Aqueous dexamethasone eye drops. J. Pharm. Pharmacol. Ther. 59:629-635, 2007.
    • (2007) J. Pharm. Pharmacol. Ther , vol.59 , pp. 629-635
    • Loftsson, T.1    Hreinsdottir, D.2    Stefansson, E.3
  • 27
    • 0032799705 scopus 로고    scopus 로고
    • High concentration of dexamethasone in aqueous and vitreous after subconjunctival injection
    • Weijtens, O., Feron, E.J., Schoemaker, R.C., et al. High concentration of dexamethasone in aqueous and vitreous after subconjunctival injection. Am. J. Ophthalmol. 128:192-197, 1999.
    • (1999) Am. J. Ophthalmol , vol.128 , pp. 192-197
    • Weijtens, O.1    Feron, E.J.2    Schoemaker, R.C.3
  • 28
    • 0036788564 scopus 로고    scopus 로고
    • Intraocular penetration and systemic absorption after topical application of dexamethasone disodium phosphate
    • Weijtens, O., Schoemaker, R.C., Romijn, F.P., et al. Intraocular penetration and systemic absorption after topical application of dexamethasone disodium phosphate. Ophthalmology 109:1887-1891, 2002.
    • (2002) Ophthalmology , vol.109 , pp. 1887-1891
    • Weijtens, O.1    Schoemaker, R.C.2    Romijn, F.P.3
  • 29
    • 0035676467 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye: Some insights on the penetration pathways after subconjunctival injection
    • Lee, T.W., and Robinson, J.R. Drug delivery to the posterior segment of the eye: some insights on the penetration pathways after subconjunctival injection. J. Ocul. Pharmacol. Ther. 17:565-572, 2001.
    • (2001) J. Ocul. Pharmacol. Ther , vol.17 , pp. 565-572
    • Lee, T.W.1    Robinson, J.R.2
  • 30
    • 17644426066 scopus 로고    scopus 로고
    • Assessment of subconjunctival delivery with model ionic permeants and magnetic resonance imaging
    • Li, S.K., Molokhia, S.A., and Jeong, E.K. Assessment of subconjunctival delivery with model ionic permeants and magnetic resonance imaging. Pharm. Res. 21:2175-2184, 2004.
    • (2004) Pharm. Res , vol.21 , pp. 2175-2184
    • Li, S.K.1    Molokhia, S.A.2    Jeong, E.K.3
  • 31
    • 0020629557 scopus 로고
    • Topically applied oxymetazoline. Ocular vasoconstrictive activity, pharmacokinetics, and metabolism
    • Duzman, E., Anderson, J., Vita, J.B., et al. Topically applied oxymetazoline. Ocular vasoconstrictive activity, pharmacokinetics, and metabolism. Arch. Ophthalmol. 101:1122-1126, 1983.
    • (1983) Arch. Ophthalmol , vol.101 , pp. 1122-1126
    • Duzman, E.1    Anderson, J.2    Vita, J.B.3
  • 32
    • 0026036445 scopus 로고
    • Effect of topically applied oxymetazoline on tear volume and tear flow in humans
    • Gobbels, M.J., Achten, C., and Spitznas, M. Effect of topically applied oxymetazoline on tear volume and tear flow in humans. Graefe's Arch. Clin. Exp. Ophthalmol. 229:147-149, 1991.
    • (1991) Graefe's Arch. Clin. Exp. Ophthalmol , vol.229 , pp. 147-149
    • Gobbels, M.J.1    Achten, C.2    Spitznas, M.3
  • 33
    • 0027523025 scopus 로고
    • Effect of oxymetazoline on aqueous humor dynamics and ocular blood flow in monkeys and rabbits
    • Wang, R.F., Lee, P.Y., Taniguchi, T., et al. Effect of oxymetazoline on aqueous humor dynamics and ocular blood flow in monkeys and rabbits. Arch. Ophthalmol. 111:535-538, 1993.
    • (1993) Arch. Ophthalmol , vol.111 , pp. 535-538
    • Wang, R.F.1    Lee, P.Y.2    Taniguchi, T.3
  • 34
    • 0029822963 scopus 로고    scopus 로고
    • Oxymetazoline: Potential mechanisms of inhibitory effects on aqueous humor dynamics
    • Chu, T.C., Ogidigben, M.J., and Potter, D.E. Oxymetazoline: Potential mechanisms of inhibitory effects on aqueous humor dynamics. Pharmacology 53:259-270, 1996.
    • (1996) Pharmacology , vol.53 , pp. 259-270
    • Chu, T.C.1    Ogidigben, M.J.2    Potter, D.E.3
  • 35
    • 0032710264 scopus 로고    scopus 로고
    • The effect of intraocular pressure on human and rabbit scleral permeability
    • Rudnick, D.E., Noonan, J.S., Geroski, D.H., et al. The effect of intraocular pressure on human and rabbit scleral permeability. Invest. Ophthalmol. Vis. Sci. 40:3054-3058, 1999.
    • (1999) Invest. Ophthalmol. Vis. Sci , vol.40 , pp. 3054-3058
    • Rudnick, D.E.1    Noonan, J.S.2    Geroski, D.H.3
  • 36
    • 0036207585 scopus 로고    scopus 로고
    • Adrenergic supersensitivity of rabbit choroidal blood vessels after sympathetic denervation
    • Chou, P.I., Lu, D.W., and Chen, J.T. Adrenergic supersensitivity of rabbit choroidal blood vessels after sympathetic denervation. Curr. Eye Res. 23:352-356, 2001.
    • (2001) Curr. Eye Res , vol.23 , pp. 352-356
    • Chou, P.I.1    Lu, D.W.2    Chen, J.T.3
  • 37
    • 35148895808 scopus 로고    scopus 로고
    • Effects of topical clonidine versus brimonidine on choroidal blood flow and intraocular pressure during squatting
    • Weigert, G., Resch, H., Garhofer, G., et al. Effects of topical clonidine versus brimonidine on choroidal blood flow and intraocular pressure during squatting. Invest. Ophthalmol. Vis. Sci. 48:4220-4225, 2007.
    • (2007) Invest. Ophthalmol. Vis. Sci , vol.48 , pp. 4220-4225
    • Weigert, G.1    Resch, H.2    Garhofer, G.3
  • 38
    • 0018573154 scopus 로고
    • Oxymetazoline in the treatment of allergic and noninfectious conjunctivitis
    • Fox, S.L., Samson, C.R., and Danzig, M.R. Oxymetazoline in the treatment of allergic and noninfectious conjunctivitis. J. Int. Med. Res. 7:528-530, 1979.
    • (1979) J. Int. Med. Res , vol.7 , pp. 528-530
    • Fox, S.L.1    Samson, C.R.2    Danzig, M.R.3
  • 39
    • 0030879878 scopus 로고    scopus 로고
    • Efficacy of oxymetazoline eye drops in noninfectious conjunctivitis, the most common cause of acute red eyes
    • Xuan, B., and Chiou, G.C. Efficacy of oxymetazoline eye drops in noninfectious conjunctivitis, the most common cause of acute red eyes. J. Ocul. Pharmacol. Ther. 13:363-367, 1997.
    • (1997) J. Ocul. Pharmacol. Ther , vol.13 , pp. 363-367
    • Xuan, B.1    Chiou, G.C.2
  • 40
    • 0022641340 scopus 로고
    • Efficacy and safety of topical oxymetazoline in treating allergic and environmental conjunctivitis
    • Duzman, E., Warman, A., and Warman, R. Efficacy and safety of topical oxymetazoline in treating allergic and environmental conjunctivitis. Ann. Ophthalmol. 18:28-31, 1986.
    • (1986) Ann. Ophthalmol , vol.18 , pp. 28-31
    • Duzman, E.1    Warman, A.2    Warman, R.3
  • 41
    • 0018971451 scopus 로고
    • Safety and toleration of oxymetazoline ophthalmic solution
    • Samson, C.R., Danzig, M.R., Sasovetz, D., et al. Safety and toleration of oxymetazoline ophthalmic solution. Pharmatherapeutica 2:347-352, 1980.
    • (1980) Pharmatherapeutica , vol.2 , pp. 347-352
    • Samson, C.R.1    Danzig, M.R.2    Sasovetz, D.3
  • 42
    • 34648813924 scopus 로고    scopus 로고
    • Regulation of choroidal blood flow during combined changes in intraocular pressure and arterial blood pressure
    • Polska, E., Simader, C., Weigert, G., et al. Regulation of choroidal blood flow during combined changes in intraocular pressure and arterial blood pressure. Invest. Ophthalmol. Vis. Sci. 48:3768-3774, 2007.
    • (2007) Invest. Ophthalmol. Vis. Sci , vol.48 , pp. 3768-3774
    • Polska, E.1    Simader, C.2    Weigert, G.3


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