-
1
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
Rubinsztein DC. The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 2006; 443:780-6.
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
2
-
-
0036566266
-
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
-
Ravikumar B, Duden R, Rubinsztein DC. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum Mol Genet 2002; 11:1107-17.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1107-1117
-
-
Ravikumar, B.1
Duden, R.2
Rubinsztein, D.C.3
-
3
-
-
33644540193
-
Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway
-
Yamamoto A, Cremona ML, Rothman JE. Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway. J Cell Biol 2006; 172:719-31.
-
(2006)
J Cell Biol
, vol.172
, pp. 719-731
-
-
Yamamoto, A.1
Cremona, M.L.2
Rothman, J.E.3
-
4
-
-
0041589248
-
α-Synuclein is degraded by both autophagy and the proteasome
-
Webb JL, Ravikumar B, Atkins J, Skepper JN, Rubinsztein DC. α-Synuclein is degraded by both autophagy and the proteasome. J Biol Chem 2003; 278:25009-13.
-
(2003)
J Biol Chem
, vol.278
, pp. 25009-25013
-
-
Webb, J.L.1
Ravikumar, B.2
Atkins, J.3
Skepper, J.N.4
Rubinsztein, D.C.5
-
5
-
-
4344659685
-
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
-
Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D. Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy. Science 2004; 305:1292-5.
-
(2004)
Science
, vol.305
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stefanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
6
-
-
38849174979
-
Dopamine-modified α-synuclein blocks chaperone-mediated autophagy
-
Martinez Vicente M, Talloczy Z, Kaushik S, Massey AC, Mazzulli J, Mosharov EV, Hodara R, Fredenburg R, Wu DC, Follenzi A, Dauer W, Przedborski S, Ischiropoulos H, Lansbury PT, Sulzer D, Cuervo AM. Dopamine-modified α-synuclein blocks chaperone-mediated autophagy. J Clin Invest 2008; 118:777-88.
-
(2008)
J Clin Invest
, vol.118
, pp. 777-788
-
-
Martinez Vicente, M.1
Talloczy, Z.2
Kaushik, S.3
Massey, A.C.4
Mazzulli, J.5
Mosharov, E.V.6
Hodara, R.7
Fredenburg, R.8
Wu, D.C.9
Follenzi, A.10
Dauer, W.11
Przedborski, S.12
Ischiropoulos, H.13
Lansbury, P.T.14
Sulzer, D.15
Cuervo, A.M.16
-
7
-
-
44349107112
-
Autophagy induced by Alexander Disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways
-
doi: 10.1093/hmg/ddn042 [Epub ahead of print
-
Tang G, Yue Z, Talloczy Z, Hagemann T, Messing A, Sulzer D, Goldman JE. Autophagy induced by Alexander Disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways. Human Molecular Genetics 2008; doi: 10.1093/hmg/ddn042 [Epub ahead of print].
-
(2008)
Human Molecular Genetics
-
-
Tang, G.1
Yue, Z.2
Talloczy, Z.3
Hagemann, T.4
Messing, A.5
Sulzer, D.6
Goldman, J.E.7
-
8
-
-
33846002775
-
Synergistic effects of the SAPK/JNK and the proteasome pathway on glial fibrillary acidic protein (GFAP) accumulation in Alexander disease
-
Tang G, Xu Z, Goldman JE. Synergistic effects of the SAPK/JNK and the proteasome pathway on glial fibrillary acidic protein (GFAP) accumulation in Alexander disease. J Biol Chem 2006; 281:38634-43.
-
(2006)
J Biol Chem
, vol.281
, pp. 38634-38643
-
-
Tang, G.1
Xu, Z.2
Goldman, J.E.3
-
9
-
-
0035163913
-
Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease
-
Brenner M, Johnson AB, Boespflug Tanguy O, Rodriguez D, Goldman JE, Messing A. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat Genet 2001; 27:117-20.
-
(2001)
Nat Genet
, vol.27
, pp. 117-120
-
-
Brenner, M.1
Johnson, A.B.2
Boespflug Tanguy, O.3
Rodriguez, D.4
Goldman, J.E.5
Messing, A.6
-
11
-
-
4344583898
-
Involvement of macroautophagy in the dissolution of neuronal inclusions
-
Rideout HJ, Lang Rollin I, Stefanis L. Involvement of macroautophagy in the dissolution of neuronal inclusions. Int J Biochem Cell Biol 2004; 36:2551-62.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2551-2562
-
-
Rideout, H.J.1
Lang Rollin, I.2
Stefanis, L.3
-
12
-
-
34548299555
-
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
-
Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D, Yin XM. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 2007; 171:513-24.
-
(2007)
Am J Pathol
, vol.171
, pp. 513-524
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Yoshimori, T.4
Stolz, D.B.5
Ron, D.6
Yin, X.M.7
-
13
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, Nedelsky NB, Schwartz SL, DiProspero NA, Knight MA, Schuldiner O, Padmanabhan R, Hild M, Berry DL, Garza D, Hubbert CC, Yao TP, Baehrecke EH, Taylor JP. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 2007; 447:859-63.
-
(2007)
Nature
, vol.447
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
McCray, B.A.4
Ritson, G.P.5
Nedelsky, N.B.6
Schwartz, S.L.7
DiProspero, N.A.8
Knight, M.A.9
Schuldiner, O.10
Padmanabhan, R.11
Hild, M.12
Berry, D.L.13
Garza, D.14
Hubbert, C.C.15
Yao, T.P.16
Baehrecke, E.H.17
Taylor, J.P.18
-
14
-
-
2642586352
-
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
-
Ravikumar B, Vacher C, Berger Z, Davies JE, Luo S, Oroz LG, Scaravilli F, Easton DF, Duden R, O'Kane CJ, Rubinsztein DC. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat Genet 2004; 36:585-95.
-
(2004)
Nat Genet
, vol.36
, pp. 585-595
-
-
Ravikumar, B.1
Vacher, C.2
Berger, Z.3
Davies, J.E.4
Luo, S.5
Oroz, L.G.6
Scaravilli, F.7
Easton, D.F.8
Duden, R.9
O'Kane, C.J.10
Rubinsztein, D.C.11
-
15
-
-
34548259958
-
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282:24131-45.
-
(2007)
J Biol Chem
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.A.5
Outzen, H.6
Øvervatn, A.7
Bjørkøy, G.8
Johansen, T.9
-
16
-
-
36849089101
-
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagydeficient mice
-
Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagydeficient mice. Cell 2007; 131:1149-63.
-
(2007)
Cell
, vol.131
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
Koike, M.3
Sou, Y.S.4
Ueno, T.5
Hara, T.6
Mizushima, N.7
Iwata, J.8
Ezaki, J.9
Murata, S.10
Hamazaki, J.11
Nishito, Y.12
Iemura, S.13
Natsume, T.14
Yanagawa, T.15
Uwayama, J.16
Warabi, E.17
Yoshida, H.18
Ishii, T.19
Kobayashi, A.20
Yamamoto, M.21
Yue, Z.22
Uchiyama, Y.23
Kominami, E.24
Tanaka, K.25
more..
-
17
-
-
38049056160
-
Neuronal autophagy: Going the distance to the axon
-
Yue Z, Wang QJ, Komatsu M. Neuronal autophagy: going the distance to the axon. Autophagy 2008; 4:94-6.
-
(2008)
Autophagy
, vol.4
, pp. 94-96
-
-
Yue, Z.1
Wang, Q.J.2
Komatsu, M.3
-
19
-
-
1342321743
-
Two ubiquitin-like conjugation systems essential for autophagy
-
Ohsumi Y, Mizushima N. Two ubiquitin-like conjugation systems essential for autophagy. Semin Cell Dev Biol 2004; 15:231-6.
-
(2004)
Semin Cell Dev Biol
, vol.15
, pp. 231-236
-
-
Ohsumi, Y.1
Mizushima, N.2
-
20
-
-
37549009531
-
Oridonin induced autophagy in human cervical carcinoma HeLa cells through Ras, JNK and P38 regulation
-
Cui Q, Tashiro S, Onodera S, Minami M, Ikejima T. Oridonin induced autophagy in human cervical carcinoma HeLa cells through Ras, JNK and P38 regulation. J Pharmacol Sci 2007; 105:317-25.
-
(2007)
J Pharmacol Sci
, vol.105
, pp. 317-325
-
-
Cui, Q.1
Tashiro, S.2
Onodera, S.3
Minami, M.4
Ikejima, T.5
-
21
-
-
32944460806
-
In yeast, loss of Hog1 leads to osmosensitivity of autophagy
-
Prick T, Thumm M, Kohrer K, Haussinger D, Vom Dahl S. In yeast, loss of Hog1 leads to osmosensitivity of autophagy. Biochem J 2006; 394:153-61.
-
(2006)
Biochem J
, vol.394
, pp. 153-161
-
-
Prick, T.1
Thumm, M.2
Kohrer, K.3
Haussinger, D.4
Vom Dahl, S.5
-
22
-
-
0035865679
-
Cell hydration controls autophagosome formation in rat liver in a microtubule-dependent way downstream from p38 MAPK activation
-
vom Dahl S, Dombrowski F, Schmitt M, Schliess F, Pfeifer U, Haussinger D. Cell hydration controls autophagosome formation in rat liver in a microtubule-dependent way downstream from p38 MAPK activation. Biochem J 2001; 354:31-6.
-
(2001)
Biochem J
, vol.354
, pp. 31-36
-
-
vom Dahl, S.1
Dombrowski, F.2
Schmitt, M.3
Schliess, F.4
Pfeifer, U.5
Haussinger, D.6
-
23
-
-
0037039442
-
Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway
-
Tallóczy Z, Jiang W, Virgin HW, IV, Leib DA, Scheuner D, Kaufman RJ, Eskelinen EL, Levine B. Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway. Proc Natl Acad Sci USA 2002; 99:190-5.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 190-195
-
-
Tallóczy, Z.1
Jiang, W.2
Virgin3
HW, I.V.4
Leib, D.A.5
Scheuner, D.6
Kaufman, R.J.7
Eskelinen, E.L.8
Levine, B.9
-
24
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky DJ, Abeliovich H, Agostinis, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008; 4:151-75.
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis3
|