Correlation of circulating CD133+ progenitor subclasses with a mild phenotype in duchenne muscular dystrophy patients

PLoS ONE

Volumn 3, Issue 5, 2008, Pages

  Marchesi, Chiara ^a   Belicchi, Marzia ^a   Meregalli, Mirella ^a   Farini, Andrea ^a   Cattaneo, Alessandra ^a   Parolini, Daniele ^a   Gavina, Manuela ^a   Porretti, Laura ^a   D'Angelo, Maria Grazia ^b   Bresolin, Nereo ^a   Cossu, Giulio ^c   Torrente, Yvan ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b La Nostra Famiglia   (Italy)

^c SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CD133 ANTIGEN; CD34 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; PEPTIDE;

ADOLESCENT; ADULT; AGE DISTRIBUTION; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ARTICLE; CELL DIFFERENTIATION; CELL SUBPOPULATION; CHILD; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; DISEASE MARKER; DISEASE SEVERITY; DUCHENNE MUSCULAR DYSTROPHY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR CLINICAL STUDY; PATHOGENESIS; PHENOTYPE; PROGNOSIS; PROTEIN FUNCTION; STEM CELL; BLOOD; CASE CONTROL STUDY; CLASSIFICATION; DNA MICROARRAY; HOSPITALIZATION; IMMUNOLOGY; PRESCHOOL CHILD; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; ADULT; ANTIGENS, CD; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; GLYCOPROTEINS; HUMANS; MUSCULAR DYSTROPHY, DUCHENNE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDES; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEVERITY OF ILLNESS INDEX;

EID: 48249142812     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002218     Document Type: Article

References (31)

1. Infante JP, Huszagh VA (1999) Mechanisms of resistance to pathogenesis in muscular dystrophies. Mol Cell Biochem 195: 155-67.
2. Hoffman EP, Brown RH Jr, Kunkel LM (1987) Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 51: 919-28.
3. Hoffman EP, Morgan JE, Watkins SC, Partidge TA (1990) Somatic reversion/ suppression of the mouse mdx phenotype in vivo. J Neurol Sci 99: 9-25.
4. Baumbach LL, Chamberlain JS, Ward PA, Farwell NJ, Caskey CT (1989) Molecular and clinical correlations of deletions leading to Duchenne and Becker muscular dystrophies. Neurology 39: 465-74.
5. Muntoni F, Torelli S, Ferlini A (2003) Dystrophin and mutations: one gene, several proteins, multiple phenotypes. Lancet Neurol 2: 731-40.
6. Finsterer J, Stollberger C (2003) The heart in human dystrophinopathies. Cardiology 99: 1-19.
7. Eagle M, Baudouin SV, Chandler C, Giddings DR, Bullock R, et al. (2002) Survival in Duchenne muscular dystrophy: improvements in life expectancy since 1967 and the impact of home nocturnal ventilation. Neuromuscul Disord 12: 926-9.
8. Phillips MF, Quinlivan RC, Edwards RH, Calverley PM (2001) Changes in spirometry over time as a prognostic marker in patients with Duchenne muscular dystrophy. Am J Respir Crit Care Med 164: 2191-94.
9. Lorenz MW, von Kegler S, Markus HS, Sitzer M (2006) Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke 37: 87-92.
10. Wilson P, D'Agostino R, Levy D, Belanger A, Silbershatz H, et al. (1998) Prediction of coronary heart disease using risk factor categories. Circulation 97: 1837-47.
11. Makita S, Nakamura M, Hiramori K (2005) The association of c-reactive protein levels with carotid intima-media complex thickness and plaque formation in the general population. Stroke 36: 2138-2142.
12. De Groot E, Hovingh GK, Wiegman A, Duriez P, Smit AJ, et al. (2004) Measurement of arterial wall thickness as a surrogate marker for atherosclerosis. Circulation 109 (23 Suppl 1): III33-8.
13. Boos CJ, Lip GY, Blann AD (2006) Circulating endothelial cells in cardiovascular disease. J Am Coll Cardiol 48: 1538-47.
14. Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, et al. (2005) Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 353: 999-1007.
15. Fadini GP, Schiavon M, Cantini M, Baesso I, Facco M, et al. (2006) Circulating progenitor cells are reduced in patients with severe lung disease. Stem Cells 24: 1806-13.
16. Torrente Y, Belicchi M, Sampaolesi M, Pisati F, Meregalli M, et al. (2004) Human circulating AC133(+) stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle. J Clin Invest 14: 182-195.
17. Miraglia S, Godfrey W, Yin AH, Atkins K, Warnke R, et al. (1997) A novel five-transmembrane hematopoietic stem cell antigen: isolation, characterization, and molecular cloning. Blood 90: 5013-21.
18. Gallacher L, Murdoch B, Wu DM, Karanu FN, Keeney M, et al. (2000) Isolation and characterization of human CD34(-)Lin(-) and CD34(+)Lin(-) hematopoietic stem cells using cell surface markers AC133 and CD7. Blood 95: 2813-20.
19. Scott E, Mawson SJ (2006) Measurement in Duchenne muscular dystrophy: considerations in the development ofa neuromuscular assessment tool. Dev Med Child Neurol 48: 540-544.
20. Gavina M, Belicchi M, Rossi B, Ottoboni L, Colombo F, et al. (2006) VCAM-1 expression on dystrophic muscle vessels has a critical role in the recruitment of human blood-derived CD133+ stem cells after intra-arterial transplantation. Blood 108: 2857-66.
21. Guven H, Shepherd RM, Bach RG, Capoccia BJ, Link DC (2006) The number of endothelial progenitor cell colonies in the blood is increased in patients with angiographically significant coronary artery disease. J Am Coll Cardiol 48: 1579-87.
22. Duda DG, Cohen KS, di Tomaso E, Au P, Klein RJ, et al. (2006) Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarker for antiangiogenic therapy. J Clin Oncol 24: 1449-1453.
23. Dome B, Timar J, Meszaros L, Raso E, Paku S, et al. (2006) Identification and clinical significance of circulating endothelial progenitor cells in human non-small cell lung cancer. Cancer Res 66: 7341-7.
24. Derfoul A, Perkins GL, Hall DJ, Tuan RS (2006) Glucocorticoids promote chondrogenic differentiation of adult human mesenchymal stem cells by enhancing expression of cartilage extracellular matrix genes. Stem Cells 24: 1487-95.
25. Sabolek M, Herborg A, Schwarz J, Storch A (2006) Dexamethasone blocks astroglial differentiation from neural precursors cells. Neuroreport 7: 1719-23.
26. Grafte-Faure S, Leveque C, Vasse M, Soria C, Norris V, et al. (1999) Effects of glucocorticoids and mineralcorticoids on proliferation and maturation of human peripheral bllod stem cells. Am J Hematol 62: 65-73.
27. Scott OM, Hyde SA, Goddard C, Dubowitz V (1982) Quantitation of muscle function in children: a prospective study in Duchenne muscular dystrophy. Muscle & Nerve 5: 291-301.
28. Brooke MH, Fenichel GM, Griggs RC, Mendell JR, Moxley R, et al. (1989) Duchenne muscular dystrophy: patterns of clinical progression and effect of supportive therapy. Neurology 39: 475-81.
29. Angelini C, Fanin M, Freda MP, Martinello F, Miorin M, et al. (1996) Prognostic factors in mild dystophinopathies. J Neurol Sci 142: 70-78.
30. Hyde SA, Steffensen BF, Floytrup I, Glent S, Kroksmark AK, et al. (2001) Longitudinal data analysis: an application to construction of a natural history profile of Duchenne muscular dystrophy. Neuromuscul Disord 11: 165-70.
31. Del Papa N, Colombo G, Fracchiolla N, Moronetti LM, Ingegnoli F, et al. (2004) Circulating endothelial cells as a marker of ongoing vascular disease in systemic sclerosis. Arthritis Rheum 50: 1296-304.