Posttranslational regulation of Neurospora circadian clock by CK1a-dependent phosphorylation

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 72, Issue , 2007, Pages 177-183

  Querfurth, C ^a   Diernfellner, A ^a   Heise, F ^a   Lauinger, L ^a   Neiss, A ^a   Tataroglu, O ^a   Brunner, M ^a   Schafmeier, T ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE I; DNA BINDING PROTEIN; DRUG DERIVATIVE; FRQ PROTEIN, NEUROSPORA CRASSA; FUNGAL PROTEIN; IC 261; INDOLE DERIVATIVE; ISOENZYME; PHLOROGLUCINOL; PROTEIN KINASE INHIBITOR; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CLOCK; WHITE COLLAR 2 PROTEIN, NEUROSPORA; CASEIN KINASE IALPHA; MESSENGER RNA; UNCLASSIFIED DRUG; WC 2 PROTEIN;

BIOLOGICAL MODEL; CIRCADIAN RHYTHM; DRUG ANTAGONISM; FEEDBACK SYSTEM; FUNGAL GENE; GENETICS; METABOLISM; NEUROSPORA; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; REVIEW; ALTERNATIVE RNA SPLICING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FUNGAL GENOME; IN VITRO STUDY; IN VIVO STUDY; NEGATIVE FEEDBACK; NONHUMAN; PROTEIN PROTEIN INTERACTION;

CASEIN KINASE I; CIRCADIAN RHYTHM; DNA-BINDING PROTEINS; FEEDBACK, BIOCHEMICAL; FUNGAL PROTEINS; GENES, FUNGAL; INDOLES; ISOENZYMES; MODELS, BIOLOGICAL; NEUROSPORA; PHLOROGLUCINOL; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 48249131584     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2007.72.025     Document Type: Conference Paper

References (32)

1. Behrend L., Milne D.M., Stoter M., Deppert W., Campbell L.E., Meek D.W., and Knippschild U. 2000. IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and - epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects. Oncogene 19: 5303.
2. Blau J. 2003. A new role for an old kinase: CK2 and the circadian clock. Nat. Neurosci. 6: 208.
3. Brunner M. and Schafmeier T. 2006. Transcriptional and posttranscriptional regulation of the circadian clock of cyanobacteria and Neurospora. Genes Dev. 20: 1061.
4. Camacho F., Cilio M., Guo Y., Virshup D.M., Patel K., Khorkova O., Styren S., Morse B., Yao Z., and Keesler G.A. 2001. Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2. FEBS Lett. 489: 159.
5. Cheng P., Yang Y., and Liu Y. 2001. Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock. Proc. Natl. Acad. Sci. 98: 7408.
6. Diernfellner A.C.R., Schafmeier T., Merrow M.W., and Brunner M. 2005. Molecular mechanism of temperature-sensing by the circadian clock of Neurospora crassa. Genes Dev. 19: 1968.
7. Dunlap J.C. and Loros J.J. 2006. How fungi keep time: Circadian system in Neurospora and other fungi. Curr. Opin. Microbiol. 9: 579.
8. Eide E.J., Kang H., Crapo S., Gallego M., and Virshup D.M. 2005. Casein kinase I in the mammalian circadian clock. Methods Enzymol. 393: 408.
9. Franchi L., Fulci V., and Macino G. 2005. Protein kinase C modulates light responses in Neurospora by regulating the blue light photoreceptor WC-1. Mol. Microbiol. 56: 334.
10. Gallego M. and Virshup D.M. 2007. Post-translational modifications regulate the ticking of the circadian clock. Nat. Rev. Mol. Cell Biol. 8: 139.
11. Gorl M., Merrow M., Huttner B., Johnson J., Roenneberg T., and Brunner M. 2001. A PEST-like element in FREQUENCY determines the length of the circadian period in Neurospora crassa. EMBO J. 20: 7074.
12. Gross S.D. and Anderson R.A. 1998. Casein kinase I: Spatial organization and positioning of a multifunctional protein kinase family. Cell. Signal. 10: 699.
13. He Q., Cha J., He Q., Lee H.C., Yang Y., and Liu Y. 2006. CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop. Genes Dev. 20: 2552.
14. Kim E.Y. and Edery I. 2006. Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein. Proc. Natl. Acad. Sci. 103: 6178.
15. Kim E.Y., Bae K., Ng F.S., Glossop N.R., Hardin P.E., and Edery I. 2002. Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity. Neuron 34: 69.
16. Kloss B., Price J.L., Saez L., Blau J., Rothenfluh A., Wesley C.S., and Young M.W. 1998. The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iepsilon. Cell 94: 97.
17. Knippschild U., Gocht A., Wolff S., Huber N., Lohler J., and Stoter M. 2005. The casein kinase 1 family: Participation in multiple cellular processes in eukaryotes. Cell. Signal. 17: 675.
18. Lee K., Loros J.J., and Dunlap J.C. 2000. Interconnected feedback loops in the Neurospora circadian system. Science 289: 107.
19. Liu Y. 2005. Analysis of posttranslational regulations in the Neurospora circadian clock. Methods Enzymol. 393: 379.
20. Liu Y. and Bell-Pedersen D. 2006. Circadian rhythms in Neurospora crassa and other filamentous fungi. Eukaryot. Cell 5: 1184.
21. Liu Y., Loros J., and Dunlap J.C. 2000. Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock. Proc. Natl. Acad. Sci. 97: 234.
22. Longenecker K.L., Roach P.J., and Hurley T.D. 1998. Crystallographic studies of casein kinase I delta toward a structural understanding of auto-inhibition. Acta Crystallogr. D Biol. Crystallogr. 54: 473.
23. Mizoguchi T., Putterill J., and Ohkoshi Y. 2006. Kinase and phosphatase: The cog and spring of the circadian clock. Int. Rev. Cytol. 250: 47.
24. Nawathean P. and Rosbash M. 2004. The doubletime and CKII kinases collaborate to potentiate Drosophila PER transcriptional repressor activity. Mol. Cell 13: 213.
25. Peters J.M., McKay R.M., McKay J.P., and Graff J.M. 1999. Casein kinase I transduces Wnt signals. Nature 401: 345.
26. Pregueiro A.M., Liu Q., Baker C.L., Dunlap J.C., and Loros J.J. 2006. The Neurospora checkpoint kinase 2: A regulatory link between the circadian and cell cycles. Science 313: 644.
27. Schafmeier T., Kaldi K., Diernfellner A., Mohr C., and Brunner M. 2006. Phosphorylation-dependent maturation of Neurospora circadian clock protein from a nuclear repressor toward a cytoplasmic activator. Genes Dev. 20: 297.
28. Schafmeier T., Haase A., Kaldi K., Scholz J., Fuchs M., and Brunner M. 2005. Transcriptional feedback of Neurospora circadian clock gene by phosphorylation-dependent inactivation of its transcription factor. Cell 122: 235.
29. Yang Y., Cheng P., and Liu Y. 2002. Regulation of the Neurospora circadian clock by casein kinase II. Genes Dev. 16: 994.
30. Yang Y., Cheng P., Zhi G., and Liu Y. 2001. Identification of a calcium/calmodulin-dependent protein kinase that phosphorylates the Neurospora circadian clock protein FREQUENCY. J. Biol. Chem. 276: 41064.
31. Yang Y., Cheng P., He Q., Wang L., and Liu Y. 2003. Phosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clock. Mol. Cell. Biol. 23: 6221.
32. Yang Y., He Q., Cheng P., Wrage P., Yarden O., and Liu Y. 2004. Distinct roles for PP1 and PP2A in the Neurospora circadian clock. Genes Dev. 18: 255.