Rac1 in cortical projection neurons is selectively required for midline crossing of commissural axonal formation

European Journal of Neuroscience

Volumn 28, Issue 2, 2008, Pages 257-267

  Kassai, Hidetoshi ^a   Terashima, Toshio ^a   Fukaya, Masahiro ^b   Nakao, Kazuki ^c   Sakahara, Mizuho ^a   Watanabe, Masahiko ^b   Aiba, Atsu ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c RIKEN Center for Biosystems Dynamics Research   (Japan)

Author keywords

Cerebral cortex; Commissural axon; Knockout mice; Rac1; Rho GTPases

Indexed keywords

RAC1 PROTEIN;

AGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; CONTROLLED STUDY; HISTOPATHOLOGY; MOUSE; NERVE CELL; NERVE FIBER; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; AXONS; BRAIN; CEREBRAL CORTEX; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; NEURONS; NEUROPEPTIDES; PYRAMIDAL TRACTS; RAC GTP-BINDING PROTEINS; SYNAPTIC TRANSMISSION; TELENCEPHALON; THALAMUS; TISSUE DISTRIBUTION;

EID: 48249116360     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2008.06343.x     Document Type: Article

References (40)

1. Andrews, W., Liapi, A., Plachez, C., Camurri, L., Zhang, J., Mori, S., Murakami, F., Parnavelas, J.G., Sundaresan, V. Richards, L.J. (2006) Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. Development, 133, 2243 2252.
2. Aoki, T., Setsu, T., Okado, H., Mikoshiba, K., Watanabe, Y. Terashima, T. (2001) Callosal commissural neurons of Dab1 deficient mutant mouse, yotari. Neurosci. Res., 41, 13 23.
3. Aoki, K., Nakamura, T. Matsuda, M. (2004) Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neurite outgrowth in PC12 cells. J. Biol. Chem., 279, 713 719.
4. Ayala, R., Shu, T. Tsai, L.H. (2007) Trekking across the brain: the journey of neuronal migration. Cell, 128, 29 43.
5. Bagri, A., Marin, O., Plump, A.S., Mak, J., Pleasure, S.J., Rubenstein, J.L. Tessier-Lavigne, M. (2002) Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron, 33, 233 248.
6. Bolis, A., Corbetta, S., Cioce, A. de Curtis, I. (2003) Differential distribution of Rac1 and Rac3 GTPases in the developing mouse brain: implications for a role of Rac3 in Purkinje cell differentiation. Eur. J. Neurosci., 18, 2417 2424.
7. Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248 254.
8. Cappello, S., Attardo, A., Wu, X., Iwasato, T., Itohara, S., Wilsch-Brauninger, M., Eilken, H.M., Rieger, M.A., Schroeder, T.T., Huttner, W.B., Brakebusch, C. Gotz, M. (2006) The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nat. Neurosci., 9, 1099 1107.
9. Chen, L., Liao, G., Yang, L., Campbell, K., Nakafuku, M., Kuan, C.Y. Zheng, Y. (2006) Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. Proc. Natl Acad. Sci. USA, 103, 16520 16525.
10. Chen, L., Liao, G., Waclaw, R.R., Burns, K.A., Linquist, D., Campbell, K., Zheng, Y. Kuan, C.Y. (2007) Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons. J. Neurosci., 27, 3884 3893.
11. Fazeli, A., Dickinson, S.L., Hermiston, M.L., Tighe, R.V., Steen, R.G., Small, C.G., Stoeckli, E.T., Keino-Masu, K., Masu, M., Rayburn, H., Simons, J., Bronson, R.T., Gordon, J.I., Tessier-Lavigne, M. Weinberg, R.A. (1997) Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature, 386, 796 804.
12. Glogauer, M., Marchal, C.C., Zhu, F., Worku, A., Clausen, B.E., Foerster, I., Marks, P., Downey, G.P., Dinauer, M. Kwiatkowski, D.J. (2003) Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions. J. Immunol., 170, 5652 5657.
13. Govek, E.E., Newey, S.E. Van Aelst, L. (2005) The role of the Rho GTPases in neuronal development. Genes Dev., 19, 1 49.
14. Gulisano, M., Broccoli, V., Pardini, C. Boncinelli, E. (1996) Emx1 and Emx2 show different patterns of expression during proliferation and differentiation of the developing cerebral cortex in the mouse. Eur. J. Neurosci., 8, 1037 1050.
15. Hanashima, C., Molnar, Z. Fishell, G. (2006) Building bridges to the cortex. Cell, 125, 24 27.
16. Hebert, J.M. McConnell, S.K. (2000) Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures. Dev. Biol., 222, 296 306.
17. Iwasato, T., Datwani, A., Wolf, A.M., Nishiyama, H., Taguchi, Y., Tonegawa, S., Knopfel, T., Erzurumlu, R.S. Itohara, S. (2000) Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex. Nature, 406, 726 731.
18. Kawauchi, T., Chihama, K., Nabeshima, Y. Hoshino, M. (2003) The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration. EMBO J., 22, 4190 4201.
19. Kwiatkowski, A.V., Rubinson, D.A., Dent, E.W., Edward van Veen, J., Leslie, J.D., Zhang, J., Mebane, L.M., Philippar, U., Pinheiro, E.M., Burds, A.A., Bronson, R.T., Mori, S., Fassler, R. Gertler, F.B. (2007) Ena/VASP Is required for neuritogenesis in the developing cortex. Neuron, 56, 441 455.
20. Lindwall, C., Fothergill, T. Richards, L.J. (2007) Commissure formation in the mammalian forebrain. Curr. Opin. Neurobiol., 17, 3 14.
21. Lopez-Bendito, G. Molnar, Z. (2003) Thalamocortical development: how are we going to get there? Nat. Rev. Neurosci., 4, 276 289.
22. Luo, L., Jan, L.Y. Jan, Y.N. (1997) Rho family GTP-binding proteins in growth cone signalling. Curr. Opin. Neurobiol., 7, 81 86.
23. Mendes, S.W., Henkemeyer, M. Liebl, D.J. (2006) Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J. Neurosci., 26, 882 892.
24. Menzies, A.S., Aszodi, A., Williams, S.E., Pfeifer, A., Wehman, A.M., Goh, K.L., Mason, C.A., Fassler, R. Gertler, F.B. (2004) Mena and vasodilator-stimulated phosphoprotein are required for multiple actin-dependent processes that shape the vertebrate nervous system. J. Neurosci., 24, 8029 8038.
25. Molyneaux, B.J., Arlotta, P., Menezes, J.R. Macklis, J.D. (2007) Neuronal subtype specification in the cerebral cortex. Nat. Rev. Neurosci., 8, 427 437.
26. Negishi, M. Katoh, H. (2002) Rho family GTPases as key regulators for neuronal network formation. J. Biochem. (Tokyo), 132, 157 166.
27. Paul, L.K., Brown, W.S., Adolphs, R., Tyszka, J.M., Richards, L.J., Mukherjee, P. Sherr, E.H. (2007) Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity. Nat. Rev. Neurosci., 8, 287 299.
28. Sakai, K. Miyazaki, J. (1997) A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission. Biochem. Biophys. Res. Commun., 237, 318 324.
29. Schwamborn, J.C. Puschel, A.W. (2004) The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity. Nat. Neurosci., 7, 923 929.
30. Serafini, T., Colamarino, S.A., Leonardo, E.D., Wang, H., Beddington, R., Skarnes, W.C. Tessier-Lavigne, M. (1996) Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell, 87, 1001 1014.
31. Shen, Y., Mani, S., Donovan, S.L., Schwob, J.E. Meiri, K.F. (2002) Growth-associated protein-43 is required for commissural axon guidance in the developing vertebrate nervous system. J. Neurosci., 22, 239 247.
32. Shu, T. Richards, L.J. (2001) Cortical axon guidance by the glial wedge during the development of the corpus callosum. J. Neurosci., 21, 2749 2758.
33. Shu, T., Butz, K.G., Plachez, C., Gronostajski, R.M. Richards, L.J. (2003) Abnormal development of forebrain midline glia and commissural projections in Nfia knock-out mice. J. Neurosci., 23, 203 212.
34. Silver, J., Lorenz, S.E., Wahlsten, D. Coughlin, J. (1982) Axonal guidance during development of the great cerebral commissures: descriptive and experimental studies, in vivo, on the role of preformed glial pathways. J. Comp. Neurol., 210, 10 29.
35. Smith, K.M., Ohkubo, Y., Maragnoli, M.E., Rasin, M.R., Schwartz, M.L., Sestan, N. Vaccarino, F.M. (2006) Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat. Neurosci., 9, 787 797.
36. Steele-Perkins, G., Plachez, C., Butz, K.G., Yang, G., Bachurski, C.J., Kinsman, S.L., Litwack, E.D., Richards, L.J. Gronostajski, R.M. (2005) The transcription factor gene Nfib is essential for both lung maturation and brain development. Mol. Cell. Biol., 25, 685 698.
37. Sugihara, K., Nakatsuji, N., Nakamura, K., Nakao, K., Hashimoto, R., Otani, H., Sakagami, H., Kondo, H., Nozawa, S., Aiba, A. Katsuki, M. (1998) Rac1 is required for the formation of three germ layers during gastrulation. Oncogene, 17, 3427 3433.
38. Takeuchi, T., Miyazaki, T., Watanabe, M., Mori, H., Sakimura, K. Mishina, M. (2005) Control of synaptic connection by glutamate receptor delta2 in the adult cerebellum. J. Neurosci., 25, 2146 2156.
39. Wahlsten, D. (1982) Deficiency of corpus callosum varies with strain and supplier of the mice. Brain Res., 239, 329 347.
40. Yamamoto, T., Sakakibara, S., Mikoshiba, K. Terashima, T. (2003) Ectopic corticospinal tract and corticothalamic tract neurons in the cerebral cortex of yotari and reeler mice. J. Comp. Neurol., 461, 61 75.