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Volumn 17, Issue 7, 2008, Pages 1075-1083

NOV-002, a mimetic of glutathione disulfide

Author keywords

Biomarkers; Glutathione; Lung cancer; Redox; S glutathionylation; Thiols

Indexed keywords

5,6 DIMETHYLXANTHENONE 4 ACETIC ACID; ANTINEOPLASTIC AGENT; BEVACIZUMAB; BORTEZOMIB; CARBOPLATIN; CISPLATIN; CITUXIMAB; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; ETOPOSIDE; GAMMA GLUTAMYLTRANSFERASE; GEFITINIB; GLUTATHIONE DISULFIDE; JANUS KINASE 2; LOMUSTINE; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; NOV 002; PACLITAXEL; PROTEIN DISULFIDE ISOMERASE; RESVERATROL; STAT5 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TLK 199; VASCULAR TARGETING AGENT;

EID: 48249115538     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.17.7.1075     Document Type: Article
Times cited : (33)

References (31)
  • 1
    • 48249108828 scopus 로고    scopus 로고
    • Pazoles CJ, Gernstein H. NOV-002, a chemoprotectant/immunomodulator, added to first line carboplatin/paclitaxel in advanced non-small cell lung cancer (NSCLC): a randomized phase 1/2, open label, controlled study. J Clin Oncol, 2006 ASCO Annual Meeting Proceedings Part I. 2006;24(18S Supplement):17021
    • Pazoles CJ, Gernstein H. NOV-002, a chemoprotectant/immunomodulator, added to first line carboplatin/paclitaxel in advanced non-small cell lung cancer (NSCLC): a randomized phase 1/2, open label, controlled study. J Clin Oncol, 2006 ASCO Annual Meeting Proceedings Part I. 2006;24(18S Supplement):17021
  • 2
    • 0023679751 scopus 로고
    • Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines
    • Tew KD, Bomber AM, Hoffman SJ. Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines. Cancer Res 1988;48(13):3622-5
    • (1988) Cancer Res , vol.48 , Issue.13 , pp. 3622-3625
    • Tew, K.D.1    Bomber, A.M.2    Hoffman, S.J.3
  • 3
    • 0030658870 scopus 로고    scopus 로고
    • Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalan
    • Bailey HH, Ripple G, Tutsch KD, et al. Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalan. J Natl Cancer Inst 1997;89(23):1789-96
    • (1997) J Natl Cancer Inst , vol.89 , Issue.23 , pp. 1789-1796
    • Bailey, H.H.1    Ripple, G.2    Tutsch, K.D.3
  • 4
    • 0026347638 scopus 로고
    • Phase I study of thiotepa in combination with the glutathione transferase inhibitor ethacrynic acid
    • O'dwyer PJ, Lacreta F, Nash S, et al. Phase I study of thiotepa in combination with the glutathione transferase inhibitor ethacrynic acid. Cancer Res 1991;51(22):6059-65
    • (1991) Cancer Res , vol.51 , Issue.22 , pp. 6059-6065
    • O'dwyer, P.J.1    Lacreta, F.2    Nash, S.3
  • 5
    • 0034978803 scopus 로고    scopus 로고
    • Pharmacologic of genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways
    • Ruscoe JE, Rosario LA, Wang T, et al. Pharmacologic of genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways. J Pharmacol Exp Ther 2001;298(1):339-45
    • (2001) J Pharmacol Exp Ther , vol.298 , Issue.1 , pp. 339-345
    • Ruscoe, J.E.1    Rosario, L.A.2    Wang, T.3
  • 6
    • 1542365411 scopus 로고    scopus 로고
    • Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways
    • Gate L, Majumdar RS, Lunk A, et al. Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways. J Biol Chem 2004;279(10):8608-16
    • (2004) J Biol Chem , vol.279 , Issue.10 , pp. 8608-8616
    • Gate, L.1    Majumdar, R.S.2    Lunk, A.3
  • 7
    • 0033105414 scopus 로고    scopus 로고
    • Regulation of JNK signaling by GSTp
    • Adler V, Yin Z, Fuchs SY, et al. Regulation of JNK signaling by GSTp. EMBO J 1999;18(5):1321-34
    • (1999) EMBO J , vol.18 , Issue.5 , pp. 1321-1334
    • Adler, V.1    Yin, Z.2    Fuchs, S.Y.3
  • 8
    • 0035877779 scopus 로고    scopus 로고
    • Glutathione S -transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus
    • Wang T, Arifoglu P, Ronai Z, et al. Glutathione S -transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus. J Biol Chem 2001;276(24):20999-1003
    • (2001) J Biol Chem , vol.276 , Issue.24 , pp. 20999-21003
    • Wang, T.1    Arifoglu, P.2    Ronai, Z.3
  • 9
    • 0032539920 scopus 로고    scopus 로고
    • Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns
    • Peterson J D, Herzenberg LA, Vasquez K, et al. Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns. Proc Natl Acad Sci USA 1998;95(6):3071-6
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.6 , pp. 3071-3076
    • Peterson, J.D.1    Herzenberg, L.A.2    Vasquez, K.3
  • 10
    • 0031042638 scopus 로고    scopus 로고
    • Glutathione deficiency is associated with impaired survival in HIV disease
    • Herzenberg LA, De Rosa SC, Dubs JG, et al. Glutathione deficiency is associated with impaired survival in HIV disease. Proc Natl Acad Sci USA 1997;94(5):1967-72
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.5 , pp. 1967-1972
    • Herzenberg, L.A.1    De Rosa, S.C.2    Dubs, J.G.3
  • 11
    • 34547534665 scopus 로고    scopus 로고
    • Could we expect to improve survival in small cell lung cancer?
    • El Maalouf G, Rodier JM, Faivre S, et al. Could we expect to improve survival in small cell lung cancer? Lung Cancer 2007;57(Suppl 2):S30-4
    • (2007) Lung Cancer , vol.57 , Issue.SUPPL. 2
    • El Maalouf, G.1    Rodier, J.M.2    Faivre, S.3
  • 12
    • 34748903521 scopus 로고    scopus 로고
    • Limited-stage small-cell lung cancer: The current status of combined-modality therapy
    • Socinski MA, Bogart JA. Limited-stage small-cell lung cancer: the current status of combined-modality therapy. J Clin Oncol 2007;25(26):4137-45
    • (2007) J Clin Oncol , vol.25 , Issue.26 , pp. 4137-4145
    • Socinski, M.A.1    Bogart, J.A.2
  • 13
    • 34250855750 scopus 로고    scopus 로고
    • Current treatment paradigms for locally advanced non-small cell lung cancer
    • Rigas JR, Kelly K. Current treatment paradigms for locally advanced non-small cell lung cancer. J Thorac Oncol 2007;2(Suppl 2):S77-85
    • (2007) J Thorac Oncol , vol.2 , Issue.SUPPL. 2
    • Rigas, J.R.1    Kelly, K.2
  • 14
    • 42349109794 scopus 로고    scopus 로고
    • NOV-002, a glutathione disulfide, mimetic, as a modulator of cellular redox balance
    • Townsend DM, HE L, Hutchens S, et al. NOV-002, a glutathione disulfide, mimetic, as a modulator of cellular redox balance. Cancer Res 2008;68:2870-7
    • (2008) Cancer Res , vol.68 , pp. 2870-2877
    • Townsend, D.M.1    HE, L.2    Hutchens, S.3
  • 15
    • 0024264526 scopus 로고
    • Glutathione metabolism and its selective modification
    • Meister A. Glutathione metabolism and its selective modification. J Biol Chem 1988;263(33):17205-8
    • (1988) J Biol Chem , vol.263 , Issue.33 , pp. 17205-17208
    • Meister, A.1
  • 16
    • 0035930608 scopus 로고    scopus 로고
    • Reversible glutathionylation regulates actin polymerization in A431 cells
    • Wang J, Boja ES, Tan W, et al. Reversible glutathionylation regulates actin polymerization in A431 cells. J Biol Chem 2001;276(51):47763-6
    • (2001) J Biol Chem , vol.276 , Issue.51 , pp. 47763-47766
    • Wang, J.1    Boja, E.S.2    Tan, W.3
  • 17
    • 38349049487 scopus 로고    scopus 로고
    • S-glutathionylation: Indicator of cell stress and regulator of the unfolded protein response
    • Townsend DM. S-glutathionylation: indicator of cell stress and regulator of the unfolded protein response. Mol Interv 2007;7(6):313-24
    • (2007) Mol Interv , vol.7 , Issue.6 , pp. 313-324
    • Townsend, D.M.1
  • 18
    • 33644669954 scopus 로고    scopus 로고
    • The utility of N,N-biotinyl glutathione disulfide in the study of protein S-glutathiolation
    • Brennan JP, Miller JI, Fuller W, et al. The utility of N,N-biotinyl glutathione disulfide in the study of protein S-glutathiolation. Mol Cell Proteomics 2006;5(2):215-25
    • (2006) Mol Cell Proteomics , vol.5 , Issue.2 , pp. 215-225
    • Brennan, J.P.1    Miller, J.I.2    Fuller, W.3
  • 19
    • 34548081774 scopus 로고    scopus 로고
    • Gamma-glutamyltransferase, redox regulation and cancer drug resistance
    • Pompella A, Corti A, Paolicchi A, et al. Gamma-glutamyltransferase, redox regulation and cancer drug resistance. Curr Opin Pharmacol 2007;7(4):360-6
    • (2007) Curr Opin Pharmacol , vol.7 , Issue.4 , pp. 360-366
    • Pompella, A.1    Corti, A.2    Paolicchi, A.3
  • 20
    • 18344387893 scopus 로고    scopus 로고
    • Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase
    • Sekhar KR, Spitz DR, Harris S, et al. Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase. Free Radic Biol Med 2002;32(7):650-62
    • (2002) Free Radic Biol Med , vol.32 , Issue.7 , pp. 650-662
    • Sekhar, K.R.1    Spitz, D.R.2    Harris, S.3
  • 21
    • 0032838830 scopus 로고    scopus 로고
    • 2 production and S-thiolation
    • 2 production and S-thiolation. Free Radic Biol Med 1999;27:623-35
    • (1999) Free Radic Biol Med , vol.27 , pp. 623-635
    • Dominici, S.1
  • 22
    • 33646698875 scopus 로고    scopus 로고
    • Extracellular disulfide exchange and the regulation of cellular function
    • Jordan PA, Gibbins JM. Extracellular disulfide exchange and the regulation of cellular function. Antioxid Redox Signal 2006;8(3-4):312-24
    • (2006) Antioxid Redox Signal , vol.8 , Issue.3-4 , pp. 312-324
    • Jordan, P.A.1    Gibbins, J.M.2
  • 23
    • 0037296312 scopus 로고    scopus 로고
    • Redox control on the cell surface: Implications for HIV-1 entry
    • Matthias LJ, Hogg PJ. Redox control on the cell surface: implications for HIV-1 entry. Antioxid Redox Signal 2003;5(1):133-8
    • (2003) Antioxid Redox Signal , vol.5 , Issue.1 , pp. 133-138
    • Matthias, L.J.1    Hogg, P.J.2
  • 24
    • 0141567629 scopus 로고    scopus 로고
    • Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1
    • Lihav J, Wijnen EM, Hess O, et al. Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1. Blood 2003;102(6):2085-92
    • (2003) Blood , vol.102 , Issue.6 , pp. 2085-2092
    • Lihav, J.1    Wijnen, E.M.2    Hess, O.3
  • 25
    • 33750565442 scopus 로고    scopus 로고
    • Protein disulfide isomerase expression is related to the invasive properties of malignant glioma
    • Goplen D, Wang J, Enger PO, et al. Protein disulfide isomerase expression is related to the invasive properties of malignant glioma. Cancer Res 2006;66(20):9895-902
    • (2006) Cancer Res , vol.66 , Issue.20 , pp. 9895-9902
    • Goplen, D.1    Wang, J.2    Enger, P.O.3
  • 26
    • 0034730151 scopus 로고    scopus 로고
    • Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell
    • Smith J, Ladi E, Mayer-Proschel M, et al. Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell. Proc Natl Acad Sci USA 2000;97(18):10032-7
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.18 , pp. 10032-10037
    • Smith, J.1    Ladi, E.2    Mayer-Proschel, M.3
  • 27
    • 28844498707 scopus 로고    scopus 로고
    • Redox regulation of precursor cell function: Insights and paradoxes
    • Noble M, Mayer-Proschel M, Proschel C. Redox regulation of precursor cell function: insights and paradoxes. Antioxid Redox Signal 2005;7(11-12):1456-67
    • (2005) Antioxid Redox Signal , vol.7 , Issue.11-12 , pp. 1456-1467
    • Noble, M.1    Mayer-Proschel, M.2    Proschel, C.3
  • 28
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
    • O'shea JJ, Gadina M, Schreiber RD. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 2002;109(Suppl):S121-31
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • O'shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 29
    • 33947381788 scopus 로고    scopus 로고
    • Redox in redux. emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation
    • Tew KD. Redox in redux. emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation. Biochem Pharmacol 2007;73(9):1257-69
    • (2007) Biochem Pharmacol , vol.73 , Issue.9 , pp. 1257-1269
    • Tew, K.D.1
  • 30
    • 21344445674 scopus 로고    scopus 로고
    • Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells
    • Filomeni G, Aquilano K, Civitareale P. et al. Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells. Free Radic Biol Med 2005;39(3):345-54
    • (2005) Free Radic Biol Med , vol.39 , Issue.3 , pp. 345-354
    • Filomeni, G.1    Aquilano, K.2    Civitareale, P.3
  • 31
    • 0037271399 scopus 로고    scopus 로고
    • Glutathione disulfide induces apoptosis in U937 cells by a redox-mediated p38 MAP kinase pathway
    • Filomeni G, Rotilio G, Ciriolo MR. Glutathione disulfide induces apoptosis in U937 cells by a redox-mediated p38 MAP kinase pathway. FASEB J 2003;171:64-6
    • (2003) FASEB J , vol.171 , pp. 64-66
    • Filomeni, G.1    Rotilio, G.2    Ciriolo, M.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.