Building the spine: The vertebrate segmentation clock

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 72, Issue , 2007, Pages 445-449

  Pourquie O ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; NOTCH RECEPTOR; TRANSCRIPTION FACTOR CLOCK; WNT PROTEIN;

AMNIOTE; CELL COMMUNICATION; CELL SYNCHRONIZATION; CIRCADIAN RHYTHM; DEVELOPMENTAL BIOLOGY; FISH; HUMAN; JARCHO LEVIN SYNDROME; MOLECULAR BIOLOGY; MORPHOGENESIS; NEGATIVE FEEDBACK; NONHUMAN; OSCILLATION; PERIODICITY; SCOLIOSIS; SIGNAL TRANSDUCTION; SOMITE; SPINE; TRANSCRIPTION REGULATION; VERTEBRATE; ANIMAL; BIOLOGICAL MODEL; BIOLOGICAL RHYTHM; FEEDBACK SYSTEM; GENETICS; MESODERM; MOUSE; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVIEW;

ANIMALS; BIOLOGICAL CLOCKS; BODY PATTERNING; FEEDBACK, BIOCHEMICAL; FISHES; HUMANS; MESODERM; MICE; MODELS, BIOLOGICAL; SCOLIOSIS; SIGNAL TRANSDUCTION; SOMITES;

EID: 48249101510     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2007.72.016     Document Type: Conference Paper

References (48)

1. Aulehla, A. and Herrmann B.G. 2004. Segmentation in vertebrates: Clock and gradient finally joined. Genes Dev. 18: 2060.
2. Aulehla A. and Johnson R.L. 1999. Dynamic expression of lunatic fringe suggests a link between notch signaling and an autonomous cellular oscillator driving somite segmentation. Dev. Biol. 207: 49.
3. Aulehla A., Wehrle C., Brand-Saberi B., Kemler R., Gossler A., Kanzler B., and Herrmann B.G. 2003. Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev. Cell 4: 395.
4. Bessho Y., Hirata H., Masamizu Y., and Kageyama R. 2003. Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock. Genes Dev. 17: 1451.
5. Bessho Y., Miyoshi G., Sakata R., and Kageyama R. 2001a. Hes7: A bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm. Genes Cells 6: 175.
6. Bessho Y., Sakata R., Komatsu S., Shiota K., Yamada S., and Kageyama R. 2001b. Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev. 15: 2642.
7. Bulman M.P., Kusumi K., Frayling T.M., McKeown C., Garrett C., Lander E.S., Krumlauf R., Hattersley A.T., Ellard S., and Turnpenny P.D. 2000. Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis. Nat. Genet. 24: 438.
8. Cooke J. and Zeeman E.C. 1976. A clock and wavefront model for control of the number of repeated structures during animal morphogenesis. J. Theor. Biol. 58: 455.
9. Dale J.K. and Pourquié O. 2000. A clock-work somite. Bioessays 22: 72.
10. Dale J.K., Malapert P., Chal J., Vilhais-Neto G., Maroto M., Johnson T., Jayasinghe S., Trainor P., Herrmann B., and Pourquié O. 2006. Oscillations of the snail genes in the presomitic mesoderm coordinate segmental patterning and morphogenesis in vertebrate somitogenesis. Dev. Cell 10: 355.
11. Davis G.K. and Patel N.H. 1999. The origin and evolution of segmentation. Trends Cell Biol. 9: M68.
12. Delfini M.C., Dubrulle J., Malapert P., Chal J., and Pourquié O. 2005. Control of the segmentation process by graded MAPK/ERK activation in the chick embryo. Proc. Natl. Acad. Sci. 102: 11343.
13. Dequeant M.L., Glynn E., Gaudenz K., Wahl M., Chen J., Mushegian A., and Pourquié O. 2006. A complex oscillating network of signaling genes underlies the mouse segmentation clock. Science 314: 1595.
14. Dubrulle J. and Pourquié O. 2004. Coupling segmentation to axis formation. Development 131: 5783.
15. Dubrulle J., McGrew M.J., and Pourquié O. 2001. FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation. Cell 106: 219.
16. Dunlap J.C. and Loros J.J. 2004. The Neurospora circadian system. J. Biol. Rhythms 19: 414.
17. Erol B., Tracy M.R., Dormans J.P., Zackai E.H., Maisenbacher M.K., O'Brien M.L., Turnpenny P.D., and Kusumi K. 2004. Congenital scoliosis and vertebral malformations: Characterization of segmental defects for genetic analysis. J. Pediatr. Orthop. 24: 674.
18. Forsberg H., Crozet F., and Brown N.A. 1998. Waves of mouse Lunatic fringe expression, in four-hour cycles at two-hour intervals, precede somite boundary formation. Curr. Biol. 8: 1027.
19. Goldbeter A., Gonze D., and Pourquié O. 2007. Sharp developmental thresholds defined through bistability by antagonistic gradients of retinoic acid and FGF signaling. Dev. Dyn. 236: 1495.
20. Henry C.A., Urban M.K., Dill K.K., Merlie J.P., Page M.F., Kimmel C.B., and Amacher S.L. 2002. Two linked hairy/Enhancer of split-related zebrafish genes, her1 and her7, function together to refine alternating somite boundaries. Development 129: 3693.
21. Holley S.A. 2007. The genetics and embryology of zebrafish metamerism. Dev. Dyn. 236: 1422.
22. Holley S.A., Geisler R., and Nüsslein-Volhard C. 2000. Control of her1 expression during zebrafish somitogenesis by a deltadependent oscillator and an independent wave-front activity. Genes Dev. 14: 1678.
23. Horikawa K., Ishimatsu K., Yoshimoto E., Kondo S., and Takeda H. 2006. Noise-resistant and synchronized oscillation of the segmentation clock. Nature 441: 719.
24. Ishimatsu K., Horikawa K., and Takeda H. 2007. Coupling cellular oscillators: A mechanism that maintains synchrony against developmental noise in the segmentation clock. Dev. Dyn. 236: 1416.
25. Jiang Y.J., Aerne B.L., Smithers L., Haddon C., Ish-Horowicz D., and Lewis J. 2000. Notch signalling and the synchronization of the somite segmentation clock. Nature 408: 475.
26. Jouve C., Palmeirim I., Henrique D., Beckers J., Gossler A., Ish-Horowicz D., and Pourquié O. 2000. Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm. Development 127: 1421.
27. Kulesa P.M., Schnell S., Rudloff S., Baker R.E., and Maini P.K. 2007. From segment to somite: Segmentation to epithelialization analyzed within quantitative frameworks. Dev. Dyn. 236: 1392.
28. Lewis J. 2003. Autoinhibition with transcriptional delay: A simple mechanism for the zebrafish somitogenesis oscillator. Curr. Biol. 13: 1398.
29. Lewis J. and Ozbudak E.M. 2007. Deciphering the somite segmentation clock: Beyond mutants and morphants. Dev. Dyn. 236: 1410.
30. Li Y., Fenger U., Niehrs C., and Pollet N. 2003. Cyclic expression of esr9 gene in Xenopus presomitic mesoderm. Differentiation 71: 83.
31. Maroto M., Dale J.K., Dequeant M.L., Petit A.C., and Pourquié O. 2005. Synchronised cycling gene oscillations in presomitic mesoderm cells require cell-cell contact. Int. J. Dev. Biol. 49: 309.
32. Masamizu Y., Ohtsuka T., Takashima Y., Nagahara H., Takenaka Y., Yoshikawa K., Okamura H., and Kageyama R. 2006. Real-time imaging of the somite segmentation clock: Revelation of unstable oscillators in the individual presomitic mesoderm cells. Proc. Natl. Acad. Sci. 103: 1313.
33. McGrew M.J., Dale J.K., Fraboulet S., and Pourquié O. 1998. The lunatic fringe gene is a target of the molecular clock linked to somite segmentation in avian embryos. Curr. Biol. 8: 979.
34. Morimoto M., Takahashi Y., Endo M., and Saga Y. 2005. The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. Nature 435: 354.
35. Oates A.C. and Ho R.K. 2002. Hairy/E(spl)-related (Her) genes are central components of the segmentation oscillator and display redundancy with the Delta/Notch signaling pathway in the formation of anterior segmental boundaries in the zebrafish. Development 129: 2929.
36. Palmeirim I., Henrique D., Ish-Horowicz D., and Pourquié O. 1997. Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesiss. Cell 91: 639.
37. Pourquié O. 2001. Vertebrate somitogenesis. Annu. Rev. Cell Dev. Biol. 17: 311.
38. Pourquié O. and Goldbeter A. 2003. Segmentation clock: Insights from computational models. Curr. Biol. 13: R632.
39. Prince V.E., Holley S.A., Bally-Cuif L., Prabhakaran B., Oates A.C., Ho R.K., and Vogt T.F. 2001. Zebrafish lunatic fringe demarcates segmental boundaries. Mech. Dev. 105: 175.
40. Richardson M.K., Allen S.P., Wright G.M., Raynaud A., and Hanken J. 1998. Somite number and vertebrate evolution. Development 125: 151.
41. Rida P.C., Le Minh N., and Jiang Y.J. 2004. A Notch feeling of somite segmentation and beyond. Dev. Biol. 265: 2.
42. Saga Y. 2007. Segmental border is defined by the key transcription factor Mesp2, by means of the suppression of notch activity. Dev. Dyn. 236: 1450.
43. Saga Y. and Takeda H. 2001. The making of the somite: Molecular events in vertebrate segmentation. Nat. Rev. Genet. 2: 835.
44. Sawada A., Shinya M., Jiang Y.J., Kawakami A., Kuroiwa A., and Takeda H. 2001. Fgf/MAPK signalling is a crucial positional cue in somite boundary formation. Development 128: 4873.
45. Sparrow D.B., Chapman G., Wouters M.A., Whittock N.V., Ellard S., Fatkin D., Turnpenny P.D., Kusumi K., Sillence D., and Dunwoodie S.L. 2006. Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype. Am. J. Hum. Genet. 78: 28.
46. Turnpenny P.D., Alman B., Cornier A.S., Giampietro P.F., Offiah A., Tassy O., Pourquié O., Kusumi K., and Dunwoodie S. 2007. Abnormal vertebral segmentation and the notch signaling pathway in man. Dev. Dyn. 236: 1456.
47. van Eeden F.J., Granato M., Schach U., Brand M., Furutani-Seiki M., Haffter P., Hammerschmidt M., Heisenberg C.P., Jiang Y.J., Kane D.A., Kelsh R.N., Mullins M.C., Odenthal J., Warga R.M., Allende M.L., Weinberg E.S., and Nüsslein-Volhard C. 1996. Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development 123: 153.
48. Whittock N.V., Sparrow D.B., Wouters M.A., Sillence D., Ellard S., Dunwoodie S.L., and Turnpenny P.D. 2004. Mutated MESP2 causes spondylocostal dysostosis in humans. Am. J. Hum. Genet. 74: 1249.