Regeneration of corneal cells and nerves in an implanted collagen corneal substitute

Cornea

Volumn 27, Issue 5, 2008, Pages 580-589

  McLaughlin, Christopher R ^a,b   Fagerholm, Per ^c   Muzakare, Lea ^a   Lagali, Neil ^a   Forrester, John V ^d   Kuffova, Lucia ^d   Rafat, Mehrdad A ^a   Liu, Yuwen ^e   Shinozaki, Naoshi ^f   Vascotto, Sandy G ^a   Munger, Rejean ^a   Griffith, May ^a,b  

^a UNIVERSITY OF OTTAWA EYE INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

^e NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^f TOKYO DENTAL COLLEGE   (Japan)

Author keywords

Collagen; Cornea; Extracellular matrix; Hydrogel; Mechanical properties; Nerve regeneration

Indexed keywords

BIOTIN; COLLAGEN TYPE 1; CYANAMIDE; BIOLOGICAL MARKER; BIOMATERIAL;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL REGENERATION; CLINICAL EXAMINATION; CONFOCAL MICROSCOPY; CONJUGATION; CONTROLLED STUDY; CORNEA CELL; CROSS LINKING; EXTRACELLULAR MATRIX; HISTOPATHOLOGY; HOST; IMPLANTATION; IN VIVO STUDY; KERATOMETRY; MINIPIG; MOUSE; NERVE REGENERATION; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SLIT LAMP; TEAR FILM; TENSILE STRENGTH; TISSUE REGENERATION; ANIMAL; ARTIFICIAL ORGAN; BAGG ALBINO MOUSE; CORNEA; CORNEA EPITHELIUM; CORNEA TRANSPLANTATION; CYTOLOGY; ENZYME IMMUNOASSAY; HYDROGEL; INNERVATION; METABOLISM; OPHTHALMIC NERVE; PHYSIOLOGY; REGENERATION; SWINE; ULTRASTRUCTURE;

ANIMALS; ARTIFICIAL ORGANS; BIOCOMPATIBLE MATERIALS; BIOLOGICAL MARKERS; COLLAGEN TYPE I; CORNEA; CORNEAL TOPOGRAPHY; CORNEAL TRANSPLANTATION; EPITHELIUM, CORNEAL; EXTRACELLULAR MATRIX; HYDROGELS; IMMUNOENZYME TECHNIQUES; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; NERVE REGENERATION; OPHTHALMIC NERVE; PROSTHESIS IMPLANTATION; REGENERATION; SWINE; SWINE, MINIATURE; TENSILE STRENGTH;

EID: 48249084610     PISSN: 02773740     EISSN: None     Source Type: Journal    
DOI: 10.1097/ICO.0b013e3181658408     Document Type: Article

References (31)

1. Duan D, Klenkler BJ, Sheardown H. Progress in the development of a corneal replacement: keratoprostheses and tissue-engineered corneas. Expert Rev Med Devices. 2006;3:59-72.
2. Nishida T. Cornea. In: Krachmer JH, Manis MJ, Holland EJ, eds. Cornea. Philadelphia: Elsevier Mosby;2005:3-26.
3. Whitcher JP, Srinivasan M, Upadhyay MP. Corneal blindness: a global perspective. Bull World Health Organ. 2001;79:214-221.
4. Chirila TV. An overview of the development of artificial corneas with porous skirts and the use of PHEMA for such an application. Biomaterials. 2001;22:3311-3317.
5. Griffith M, Fagerholm P, Liu W, et al. Corneal regenerative medicine: corneal substitutes for transplantation In: Reinhard T, Larkin F, eds. Essentials in Ophthalmology: Cornea and External Eye Diseases. Heidelberg: Springer Verlag;2008:37-53.
6. Minami Y, Sugihara H, Oono S. Reconstruction of cornea in three-dimensional collagen gel matrix culture. Invest Ophthalmol Vis Sci. 1993;34:2316-2324.
7. Dunn MW, Nishihara T, Stenzel KH, et al. Collagen-derived membrane: corneal implantation. Science. 1967;157:1329-1330.
8. Willoughby CE, Batterbury M, Kaye SB. Collagen corneal shields. Surv Ophthalmol. 2002;47:174-182.
9. Liu Y, Gan L, Carlsson DJ, et al. A simple, cross-linked collagen tissue substitute for corneal implantation. Invest Ophthalmol Vis Sci. 2006;47: 1869-1875.
10. Gratzer PF, Lee JM. Control of pH alters the type of cross-linking produced by 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC) treatment of acellular matrix vascular grafts. J Biomed Mater Res. 2001;58: 172-179.
11. Forrester JV, Kuffova L. Corneal Transplantation. London: Imperial College Press;2004.
12. She SC, Steahly LP, Moticka EJ. A method for performing full-thickness, orthotopic, penetrating keratoplasty in the mouse. Ophthalmic Surg. 1990;21:781-785.
13. Millodot M. A review of research on the sensitivity of the cornea. Ophthalmic Physiol Opt. 1984;4:305-318.
14. Tervo T, Moilanen J. In vivo confocal microscopy for evaluation of wound healing following corneal refractive surgery. Prog Retin Eye Res. 2003;22:339-358.
15. Plskova J, Kuffova L, Holan V, et al. Evaluation of corneal graft rejection in a mouse model. Br J Ophthalmol. 2002;86:108-113.
16. Meijering E, Jacob M, Sarria JC, et al. Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy images. Cytometry A. 2004;58:167-176.
17. Oliveira-Soto L, Efron N. Assessing the cornea by in vivo confocal microscopy. Clin Exp Ophthalmol. 2003;31:83-84.
18. Calvillo MP, McLaren JW, Hodge DO, et al. Corneal reinnervation after LASIK: prospective 3-year longitudinal study. Invest Ophthalmol Vis Sci. 2004;45:3991-3996.
19. Lagali NS, Griffith M, Shinozaki N, et al. Innervation of tissue-engineered corneal implants in a porcine model: a 1-year in vivo confocal microscopy study. Invest Ophthalmol Vis Sci. 2007;48:3537-3544.
20. Andreassen TT, Simonsen AH, Oxlund H. Biomechanical properties of keratoconus and normal corneas. Exp Eye Res. 1980;31:435-441.
21. Li F, Carlsson D, Lohmann C, et al. Cellular and nerve regeneration within a biosynthetic extracellular matrix for corneal transplantation. Proc Natl Acad Sci USA. 2003;100:15346-15351.
22. Liu Y, Griffith M, Watsky MA, et al. Properties of porcine and recom-binant human collagen matrices for optically clear tissue engineering applications. Biomacromolecules. 2006;7:1819-1828.
23. Kuffova L, Lumsden L, Vesela V, et al. Kinetics of leukocyte and myeloid cell traffic in the murine corneal allograft response. Transplantation. 2001;72:1292-1298.
24. Holopainen JM, Moilanen JA, Sorsa T, et al. Activation of matrix metalloproteinase-8 by membrane type 1-MMP and their expression in human tears after photorefractive keratectomy. Invest Ophthalmol Vis Sci. 2003;44:2550-2556.
25. Liu L, Kuffova L, Griffith M, et al. Immunological responses in mice to full-thickness corneal grafts engineered from porcine collagen. Biomaterials. 2007;28:3807-3814.
26. Li F, Griffith M, Li Z, et al. Recruitment of multiple cell lines by collagen-synthetic copolymer matrices in corneal regeneration. Biomaterials. 2005;26:3093-3104.
27. Meller D, Peters K, Meller K. Human cornea and sclera studied by atomic force microscopy. Cell Tissue Res. 1997;288:111-118.
28. Hoeltzel DA, Altman P, Buzard K, et al. Strip extensiometry for comparison of the mechanical response of bovine, rabbit, and human corneas. J Biomech Eng. 1992;114:202-215.
29. Kampmeier J, Radt B, Birngruber R, et al. Thermal and biomechanical parameters of porcine cornea. Cornea. 2000;19:355-363.
30. Simonsen AH, Andreassen TT, Bendix K. The healing strength of corneal wounds in the human eye. Exp Eye Res. 1982;35:287-292.
31. Zeng Y, Yang J, Huang K, et al. A comparison of biomechanical properties between human and porcine cornea. J Biomech. 2001;34:533-537.