Preparation, characterization and photoprotection of tocopherol loaded nanostructured lipid carriers

2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007

Volumn , Issue , 2007, Pages 203-208

  Ma, Q H ^a   Wang, Y W ^a   Lin, X F ^b   Luo, D ^b   Gu, N ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Cytotoxicity; Nanostrctured lipid carriers; Photoprotection; Tocopherol

Indexed keywords

BIOLOGICAL MATERIALS; BIOMEDICAL ENGINEERING; CYTOTOXICITY; DISPERSIONS; HIGH PRESSURE ENGINEERING; SIZE DISTRIBUTION; TRANSMISSION ELECTRON MICROSCOPY;

BIOCOMPATIBLE MATERIALS; CELLULAR ACTIVITIES; CELLULAR UPTAKES; HIGH PRESSURES; KERATINOCYTES; LIPID CONCENTRATIONS; LIPID CONTENTS; MTT ASSAYS; NANOMETER RANGES; NANOSTRCTURED LIPID CARRIERS; NANOSTRUCTURED LIPID CARRIERS; NARROW SIZE DISTRIBUTIONS; OPTIMAL PRODUCTIONS; PHOTOPROTECTION; SMALL PARTICLE SIZES; SPHERICAL PARTICLES; TOCOPHEROL; UVB IRRADIATIONS;

CIVIL AVIATION;

EID: 48149101260     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/ICCME.2007.4381722     Document Type: Conference Paper

References (12)

1. S. Kondo, A. Mamada, J. Yamaguchi, and S. Fukuro, "Protective effect of dl-alpha-tocopherol on the cytotoxicity of ultraviolet B against human skin fibroblasts in vitro," Photodermatol Photoimmunol Photomed, vol. 7, pp. 173-177, 1990.
2. S. Maalouf, M. El-Sabban, N. Darwiche, and H. Gali-Muhtasib, "Protective effect of vitamin E on ultraviolet B light-induced damage in keratinocytes," Mol Carcinog., vol. 34, pp. 121-130, 2002.
3. M. McVean, and D.C. Liebler, "Prevention of DNA photodamage by vitamin E compounds and sunscreens: roles of ultraviolet absorban ce and cellular uptake," Mol. Carcinog., vol. 24, pp. 169-176, 1999.
4. H. Masaki, Y. Okano, Y. Ochiai, K. Obayashi, H. Akamatsu, and H. Sakurai, "alpha-tocopherol increases the intracellular glutathione level in HaCaT keratinocytes," Free Radic. Res., vol. 36, pp. 705-709, 2002.
5. M. Uemura, H. Manabe, N. Yoshida, N. Fujita, J. Ochiai, N. Matsumoto, et al., "Alpha-tocopherol prevents apoptosis of vascular endothelial cells via a mechanism exceeding that of mere antioxidation," Eur. J. Pharmacol., vol. 456, pp. 29-37, 2002.
6. R.H. Muller, M. Radtke, and S.A. Wissing, "Nanostructured lipid matrices for improved microencapsulation of drugs," Int. J. Pharm., vol. 242, pp. 121-128, 2001.
7. R.H. Muller, K. Mader, and S. Gohla, "Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art," Eur. J. Pharm. Biopharm., vol. 50, pp. 161-177, 2000.
8. R.H. Muller, and C.M. Keck, "Challenges and solutions for the delivery of biotech drugs - a review of drug nanocrystal technology and lipid nanoparticles," J. Biotechnol., vol. 113, pp. 151-170, 2004.
9. R.H. Muller, M. Radtke, and S.A. Wissing, "Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations," Adv. Drug Deliv. Rev., vol. 54 Suppl. 1, pp. S131 - S155, 2002.
10. E.B. Souto, S.A. Wissing, C.M. Barbosa, and R.H. Muller, "Evaluation of the physical stability of SLN and NLC before and after incorporation into hydrogel formulations," Eur. J. Pharm. Biopharm., vol. 58, pp. 83-90, 2004.
11. S.A. Wissing, A. lippacher, and R.H. Muller, "Investigations on the occlusive properties of solid lipid nanoparticles (SLN)," J. Cosmet. Sci., vol. 52, pp. 313-323, 2001.
12. X.F. Lin, D. Luo, X. Ji, L.X. Xu, J. Zhu, D. Wu, et al, "Photoprotection by tocopherol submicron emulsion against UV-mediated damage in keratinocytes," J. Clin. Dematol. (Chinese), vol. 35, pp. 203-205, 2006.