Leaky enteric coating on ranitidine hydrochloride beads: Dissolution and prediction of plasma data

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 69, Issue 3, 2008, Pages 977-985

  Bendas, Ehab R ^a,b   Ayres, James W ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Absorption window; Computer simulations; Extrusion spheronization; GI transit; Leaky enteric coating; Pellets; Ranitidine hydrochloride

Indexed keywords

BUFFER; CITRIC ACID TRIETHYL ESTER; EUDRAGIT; LACTOSE; MACROGOL 8000; MICROCRYSTALLINE CELLULOSE; PHOSPHATE; POLYMER; POLYSORBATE 80; RANITIDINE; SORBITAN STEARATE; SURFACTANT; TALC;

ARTICLE; COMPUTER SIMULATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; ENTERIC COATED TABLET; GASTROINTESTINAL TRANSIT; HYDROPHILICITY; HYDROPHOBICITY; PH; SPHERONIZATION; STOMACH JUICE;

ALGORITHMS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; COMPUTER SIMULATION; EXCIPIENTS; HALF-LIFE; HISTAMINE H2 ANTAGONISTS; HUMANS; LACTOSE; MODELS, STATISTICAL; POLYETHYLENE GLYCOLS; RANITIDINE; SOLUBILITY; TABLETS, ENTERIC-COATED;

EID: 48149095501     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.02.019     Document Type: Article

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