메뉴 건너뛰기




Volumn 15, Issue 3, 1997, Pages 371-380

Recombinant bone morphogenetic protein (BMP)-2 regulates costochondral growth plate chondrocytes and induces expression of BMP-2 and BMP-4 in a cell maturation-dependent manner

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; BIOASSAY; BONE; CARTILAGE; DNA; RNA;

EID: 0031147795     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.1100150309     Document Type: Article
Times cited : (52)

References (56)
  • 1
    • 0026788486 scopus 로고
    • Effects of combining transforming growth factor beta and 1.25‐dihydroxyvitamin D3 on differentiation of a human osteosarcoma (MG‐63)
    • 1 Bonewald LF, Kester MB, Schwartz Z, Swain LD, Khare A, Johnson TL, Leach RJ, Boyan BD: Effects of combining transforming growth factor beta and 1.25‐dihydroxyvitamin D 3 on differentiation of a human osteosarcoma (MG‐63). J Biol Chem 267: 8943–8949, 1992
    • (1992) J Biol Chem , vol.267 , pp. 8943-8949
    • Bonewald, LF1    Kester, MB2    Schwartz, Z3    Swain, LD4    Khare, A5    Johnson, TL6    Leach, RJ7    Boyan, BD8
  • 2
    • 0023898906 scopus 로고
    • The effects of Vitamin D metabolites on the plasma and matrix vesicle membranes of growth and resting cartilage cells in vitro
    • 2 Boyan BD, Schwartz Z, Carnes DL Jr, Ramirez V: The effects of Vitamin D metabolites on the plasma and matrix vesicle membranes of growth and resting cartilage cells in vitro. Endocrinology 122: 2851–2860, 1988
    • (1988) Endocrinology , vol.122 , pp. 2851-2860
    • Boyan, BD1    Schwartz, Z2    Carnes, DL3    Ramirez, V4
  • 3
    • 0023769756 scopus 로고
    • Differential expression of phenotype by resting zone and growth region costochondral chondrocytes in vitro
    • 3 Boyan BD, Schwartz Z, Swain LD, Carnes DL Jr, Zislis T: Differential expression of phenotype by resting zone and growth region costochondral chondrocytes in vitro. Bone 9: 185–194, 1988
    • (1988) Bone , vol.9 , pp. 185-194
    • Boyan, BD1    Schwartz, Z2    Swain, LD3    Carnes, DL4    Zislis, T5
  • 4
    • 0026569895 scopus 로고
    • In vitro studies on the regulalion of endochondral ossification by vitamin D
    • 4 Boyan BD, Schwartz Z, Swain LD: In vitro studies on the regulalion of endochondral ossification by vitamin D. Crit Rev Oral Biol Med 3: 15–30, 1992
    • (1992) Crit Rev Oral Biol Med , vol.3 , pp. 15-30
    • Boyan, BD1    Schwartz, Z2    Swain, LD3
  • 5
    • 0026528391 scopus 로고
    • Epithelial cell lines that induce bone formation in vivo produce alkaline phosphatase‐enriched matrix vesicles in culture
    • 5 Boyan BD, Swain LD, Schwartz Z, Ramirez V, Carnes DL Jr: Epithelial cell lines that induce bone formation in vivo produce alkaline phosphatase‐enriched matrix vesicles in culture. Clin Orthop 277: 266–276, 1992
    • (1992) Clin Orthop , vol.277 , pp. 266-276
    • Boyan, BD1    Swain, LD2    Schwartz, Z3    Ramirez, V4    Carnes, DL5
  • 6
    • 0026517302 scopus 로고
    • Initial effects of partially purified bone morphogenetic protein on the expression of glycosaminoglycan, collagen, and alkaline phosphatase in nonunion cell cultures
    • 6 Boyan BD, Schwartz Z, Swain LD, Khare AG, Heckman JD, Ramirez V, Peters P, Carnes DL Jr: Initial effects of partially purified bone morphogenetic protein on the expression of glycosaminoglycan, collagen, and alkaline phosphatase in nonunion cell cultures. Clin Orthop 278: 286–304, 1992
    • (1992) Clin Orthop , vol.278 , pp. 286-304
    • Boyan, BD1    Schwartz, Z2    Swain, LD3    Khare, AG4    Heckman, JD5    Ramirez, V6    Peters, P7    Carnes, DL8
  • 7
    • 0028030079 scopus 로고
    • Latent transforming growth factor‐β is produced by chondrocytes and activated by extracellular matrix vesicles upon exposure to 1.25‐(OH)2D3
    • 7 Boyan BD, Schwartz Z, Park‐Snyder S, Dean DD, Yang F, Twardzik D, Bonewald LF: Latent transforming growth factor‐β is produced by chondrocytes and activated by extracellular matrix vesicles upon exposure to 1.25‐(OH) 2 D 3. J Biol Chem 269: 28374–28381, 1994
    • (1994) J Biol Chem , vol.269 , pp. 28374-28381
    • Boyan, BD1    Schwartz, Z2    Park‐Snyder, S3    Dean, DD4    Yang, F5    Twardzik, D6    Bonewald, LF7
  • 8
    • 0003075131 scopus 로고
    • Alkaline phosphatase, in: Methods of Enzymatic Analysis
    • 8 Bretaudiere J, Spillman T: Alkaline phosphatase. In: Methods of Enzymatic Analysis, 3rd ed, pp 75–92. Ed by HU Bergmeyer. Weinheim, Verlag Chemie, 1984
    • (1984) , pp. 75-92
    • Bretaudiere, J1    Spillman, T2
  • 9
    • 0025672641 scopus 로고
    • Identification of transforming growth factor β family members present in bone‐inductive protein purified from bovine bone
    • 9 Celeste AJ, Lannazzi JA, Taylor RC, Hewick RM, Rosen V, Wang EA, Wozney JM: Identification of transforming growth factor β family members present in bone‐inductive protein purified from bovine bone. Proc Natl Acad Sci USA 87: 9843–9847, 1990
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9843-9847
    • Celeste, AJ1    Lannazzi, JA2    Taylor, RC3    Hewick, RM4    Rosen, V5    Wang, EA6    Wozney, JM7
  • 10
    • 0028126646 scopus 로고
    • Cartilage‐derived morphogenetic proteins: New members of the transforming growth factor‐beta superfamily predominantly expressed in long bones during human embryonic development
    • 10 Chang SC, Hoang B, Thomas JT, Vukicevic S, Luyten FP, Ryba NJ, Kozak CA, Reddi AH, Moos M Jr. Cartilage‐derived morphogenetic proteins: New members of the transforming growth factor‐beta superfamily predominantly expressed in long bones during human embryonic development. J Biol Chem 269: 28227–28234, 1994
    • (1994) J Biol Chem , vol.269 , pp. 28227-28234
    • Chang, SC1    Hoang, B2    Thomas, JT3    Vukicevic, S4    Luyten, FP5    Ryba, NJ6    Kozak, CA7    Reddi, AH8    Moos, M9
  • 11
    • 0025789151 scopus 로고
    • Stimulation of chondrogenesis in limb bud mesoderm cells by recombinant human bone morphogenetic protein 2B (BMP‐2B) and modulation by transforming growth factor β1 and β2
    • 11 Chen P, Carrington JL, Hammonds RG, Reddi AH: Stimulation of chondrogenesis in limb bud mesoderm cells by recombinant human bone morphogenetic protein 2B (BMP‐2B) and modulation by transforming growth factor β1 and β2. Exp Cell Res 195: 509–515, 1991
    • (1991) Exp Cell Res , vol.195 , pp. 509-515
    • Chen, P1    Carrington, JL2    Hammonds, RG3    Reddi, AH4
  • 12
    • 0027756723 scopus 로고
    • Bovine articular chondrocytes do not undergo hypertrophy when cultured in the presence of serum and osteogenic protein‐1
    • 12 Chen P, Vukicevic S, Sampath TK, Luyten FP: Bovine articular chondrocytes do not undergo hypertrophy when cultured in the presence of serum and osteogenic protein‐1. Biochem Biophys Res Commun 197: 1253–1259, 1993
    • (1993) Biochem Biophys Res Commun , vol.197 , pp. 1253-1259
    • Chen, P1    Vukicevic, S2    Sampath, TK3    Luyten, FP4
  • 13
    • 0028887943 scopus 로고
    • Osteogenic protein‐1 promotes growth and maturation of chick sternal chondrocytes in serum‐free cultures
    • 13 Chen P, Vukicevic S, Sampath TK, Luyten FP: Osteogenic protein‐1 promotes growth and maturation of chick sternal chondrocytes in serum‐free cultures. J Cell Sci 108: 105–114, 1995
    • (1995) J Cell Sci , vol.108 , pp. 105-114
    • Chen, P1    Vukicevic, S2    Sampath, TK3    Luyten, FP4
  • 14
    • 0026319495 scopus 로고
    • Bone morphogenetic protein‐2b stimulation of growth and osteogenic phenotypes in rat osteoblast‐like cells: comparison with TGF‐β1
    • 14 Chen TL, Bates RL, Dudley A, Hammonds RG Jr, Amento EP: Bone morphogenetic protein‐2b stimulation of growth and osteogenic phenotypes in rat osteoblast‐like cells: comparison with TGF‐β1. J Bone Miner Res 6: 1387–1393, 1991
    • (1991) J Bone Miner Res , vol.6 , pp. 1387-1393
    • Chen, TL1    Bates, RL2    Dudley, A3    Hammonds, RG4    Amento, EP5
  • 15
    • 85120514949 scopus 로고
    • Interdependent regulation of chondrocyte differentiation by vitamin D metabolites and TGF‐β
    • 15 Esquivel A. Schwartz Z. Luna M. Campos R, Dean DD, Boyan BD: Interdependent regulation of chondrocyte differentiation by vitamin D metabolites and TGF‐β. Trans Orihop Res Soc 20: 390, 1995
    • (1995) Trans Orihop Res Soc , vol.20 , pp. 390
    • Esquivel, A1    Schwartz, Z2    Luna, M3    Campos, R4    Dean, DD5    Boyan, BD6
  • 16
    • 0028242526 scopus 로고
    • Structure and sequence of mouse bone morphogenetic protein‐2 gene (BMP‐2): comparison of the structures and promoter regions of BMP‐2 and BMP‐4 genes
    • 16 Feng JQ, Harris MA, Ghosh‐Choudhury N, Feng M, Mundy GR. Harris SE: Structure and sequence of mouse bone morphogenetic protein‐2 gene (BMP‐2): comparison of the structures and promoter regions of BMP‐2 and BMP‐4 genes. Biochim Biophys Acta 1218: 221–224, 1994
    • (1994) Biochim Biophys Acta , vol.1218 , pp. 221-224
    • Feng, JQ1    Harris, MA2    Ghosh‐Choudhury, N3    Feng, M4    Mundy, GR5    Harris, SE6
  • 17
    • 0028807464 scopus 로고
    • The mouse bone morphogenetic protein‐4 gene: analysis of promoter utilization in fetal rat calvarial osteoblasts and regulation by COUP‐TFI orphan receptor
    • 17 Feng JQ, Chen D, Cooney AJ, Tsai MJ, Harris MA, Tsai SY, Feng M, Mundy GR, Harris SE: The mouse bone morphogenetic protein‐4 gene: analysis of promoter utilization in fetal rat calvarial osteoblasts and regulation by COUP‐TFI orphan receptor. J Biol Chem 270: 28364–28373, 1995
    • (1995) J Biol Chem , vol.270 , pp. 28364-28373
    • Feng, JQ1    Chen, D2    Cooney, AJ3    Tsai, MJ4    Harris, MA5    Tsai, SY6    Feng, M7    Mundy, GR8    Harris, SE9
  • 18
    • 0023351938 scopus 로고
    • Bovine bone morphogenetic protein (bBMP) fraction‐induced repair of craniotomy defects in the rhesus monkey (Macaca speciosa)
    • 18 Ferguson D, Davis WL, Urist MR, Hurt WC, Allen EP: Bovine bone morphogenetic protein (bBMP) fraction‐induced repair of craniotomy defects in the rhesus monkey (Macaca speciosa). Clin Orthop 219: 251–258, 1987
    • (1987) Clin Orthop , vol.219 , pp. 251-258
    • Ferguson, D1    Davis, WL2    Urist, MR3    Hurt, WC4    Allen, EP5
  • 19
    • 0022842457 scopus 로고
    • Effect of vitamin D metabolites on the expression of alkaline phosphatase activity by epiphyseal hypertrophic chondrocytes in primary cell culture
    • 19 Hale LV, Kemick MLS, Wuthier RE: Effect of vitamin D metabolites on the expression of alkaline phosphatase activity by epiphyseal hypertrophic chondrocytes in primary cell culture. J Bone Miner Res 1: 489–495, 1986
    • (1986) J Bone Miner Res , vol.1 , pp. 489-495
    • Hale, LV1    Kemick, MLS2    Wuthier, RE3
  • 20
    • 0025361261 scopus 로고
    • Characterization of the hamster DDT1 cell aFGF/HBGF‐I gene and cDNA and its modulation by steroids
    • 20 Hall JA, Harris MA, Malark M, Mansson PE, Zhou H, Harris SE: Characterization of the hamster DDT1 cell aFGF/HBGF‐I gene and cDNA and its modulation by steroids. J Cell Biochem 43: 17–26, 1990
    • (1990) J Cell Biochem , vol.43 , pp. 17-26
    • Hall, JA1    Harris, MA2    Malark, M3    Mansson, PE4    Zhou, H5    Harris, SE6
  • 21
    • 0028341364 scopus 로고
    • Effects of transforming growth factor β on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long‐term fetal rat calvarial osteoblasts
    • 21 Harris SE, Bonewald LF, Harris MA, Sabatini M, Dallas S, Feng JQ, Ghosh‐Choudhury N, Wozney J, Mundy GR: Effects of transforming growth factor β on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long‐term fetal rat calvarial osteoblasts. J Bone Miner Res 9: 855–863, 1994
    • (1994) J Bone Miner Res , vol.9 , pp. 855-863
    • Harris, SE1    Bonewald, LF2    Harris, MA3    Sabatini, M4    Dallas, S5    Feng, JQ6    Ghosh‐Choudhury, N7    Wozney, J8    Mundy, GR9
  • 22
    • 0025974670 scopus 로고
    • Osteogenin promotes reexpression of cartilage phenotype by dedifferentiated articular chondrocytes in serum‐free medium
    • 22 Harrison ET Jr, Luyten FP, Reddi AH: Osteogenin promotes reexpression of cartilage phenotype by dedifferentiated articular chondrocytes in serum‐free medium. Exp Cell Res 192: 340–345, 1991
    • (1991) Exp Cell Res , vol.192 , pp. 340-345
    • Harrison, ET1    Luyten, FP2    Reddi, AH3
  • 23
    • 0026006594 scopus 로고
    • The use of bone morphogenetic protein in the treatment of nonunion in a canine model
    • 23 Heckman JD, Boyan BD, Aufdemorte TB, Abbott JT: The use of bone morphogenetic protein in the treatment of nonunion in a canine model. J Bone Joint Surg [Am] 73: 750–764, 1991
    • (1991) J Bone Joint Surg [Am] , vol.73 , pp. 750-764
    • Heckman, JD1    Boyan, BD2    Aufdemorte, TB3    Abbott, JT4
  • 24
    • 0026325169 scopus 로고
    • Bone morphogenetic proteins (BMP‐2 and BMP‐3) promote growth and expression of the differentiated phenotype of rabbit chondrocytes and osteoblastic. MC3T3‐E1 cells in vitro
    • 24 Hiraki Y, Inoue H, Shigeno C, Sanma Y, Bentz H, Rosen DM, Asada A, Suzuki F: Bone morphogenetic proteins (BMP‐2 and BMP‐3) promote growth and expression of the differentiated phenotype of rabbit chondrocytes and osteoblastic. MC3T3‐E1 cells in vitro. J Bone Miner Res 6: 1373–1385, 1991
    • (1991) J Bone Miner Res , vol.6 , pp. 1373-1385
    • Hiraki, Y1    Inoue, H2    Shigeno, C3    Sanma, Y4    Bentz, H5    Rosen, DM6    Asada, A7    Suzuki, F8
  • 25
    • 0344161105 scopus 로고    scopus 로고
    • TGF‐β1 treatment of resting zone chondrocytes induces differentiation into a 1,25‐(OH)2D3‐ responsive growth zone chondrocyte phenotype (abstract no. 1949)
    • 25 Holmes S, Schwartz Z, Kieswetter K, Liu Y, Campos R, Sylvia VL, Dean DD, Boyan BD: TGF‐β1 treatment of resting zone chondrocytes induces differentiation into a 1,25‐(OH) 2 D 3 ‐ responsive growth zone chondrocyte phenotype (abstract no. 1949). J Dent Res 75 (Special lssue): 261, 1996
    • (1996) J Dent Res , vol.75 , Issue.Special lssue , pp. 261
    • Holmes, S1    Schwartz, Z2    Kieswetter, K3    Liu, Y4    Campos, R5    Sylvia, VL6    Dean, DD7    Boyan, BD8
  • 26
    • 0023906710 scopus 로고
    • Bone morphogenetic protein augmentation grafting of resistant femoral nonunions: a preliminary report
    • 26 Johnson EE, Urist MR, Finerman GA: Bone morphogenetic protein augmentation grafting of resistant femoral nonunions: a preliminary report. Clin Orthop 230: 257–265, 1988
    • (1988) Clin Orthop , vol.230 , pp. 257-265
    • Johnson, EE1    Urist, MR2    Finerman, GA3
  • 27
    • 0023716334 scopus 로고
    • Repair of segmental defects of the tibia with cancellous bone grafts augmented with human bone morphogenetic protein: a preliminary report
    • 27 Johnson EE, Urist MR, Finerman GA: Repair of segmental defects of the tibia with cancellous bone grafts augmented with human bone morphogenetic protein: a preliminary report. Clin Orthop 236: 249–257, 1988
    • (1988) Clin Orthop , vol.236 , pp. 249-257
    • Johnson, EE1    Urist, MR2    Finerman, GA3
  • 28
    • 0026574058 scopus 로고
    • Resistant nonunions and partial or complete segmental defects of long bones: treatment with implants of a composite of human bone morphogenetic protein (BMP) and autolysed, antigen‐extracted, allogeneic (AAA) bone
    • 28 Johnson EE, Urist MR, Finerman GA: Resistant nonunions and partial or complete segmental defects of long bones: treatment with implants of a composite of human bone morphogenetic protein (BMP) and autolysed, antigen‐extracted, allogeneic (AAA) bone. Clin Orthop 277: 229–237, 1992
    • (1992) Clin Orthop , vol.277 , pp. 229-237
    • Johnson, EE1    Urist, MR2    Finerman, GA3
  • 29
    • 0026709638 scopus 로고
    • Natural bovine osteogenin and recombinant human bone morphogenetic protein‐2B are equipotent in the maintenance of proteoglycans in bovine articular cartilage explant cultures
    • 29 Luyten FP, Yu YM, Yanagishita M, Vukicevic S, Hammonds RG, Reddi AH: Natural bovine osteogenin and recombinant human bone morphogenetic protein‐2B are equipotent in the maintenance of proteoglycans in bovine articular cartilage explant cultures. J Biol Chem 267: 3691–3695, 1992
    • (1992) J Biol Chem , vol.267 , pp. 3691-3695
    • Luyten, FP1    Yu, YM2    Yanagishita, M3    Vukicevic, S4    Hammonds, RG5    Reddi, AH6
  • 30
    • 0028283476 scopus 로고
    • Recombinant bone morphogenetic protein‐4, transforming growth factor‐beta 1, and activin A enhance the cartilage phenotype of articular chondrocytes in vitro
    • 30 Luyten FP, Chen P, Paralkar V, Reddi AH: Recombinant bone morphogenetic protein‐4, transforming growth factor‐beta 1, and activin A enhance the cartilage phenotype of articular chondrocytes in vitro. Exp Cell Res 210: 224–229, 1994
    • (1994) Exp Cell Res , vol.210 , pp. 224-229
    • Luyten, FP1    Chen, P2    Paralkar, V3    Reddi, AH4
  • 31
    • 0024761677 scopus 로고
    • Patterns of expression of murine Vgr‐1 and BMP‐2a RNA suggest that transforming growth factor‐beta‐like genes coordinately regulate aspects of embryonic development
    • 31 Lyons KM, Pelton RW, Hogan BL: Patterns of expression of murine Vgr‐1 and BMP‐2a RNA suggest that transforming growth factor‐beta‐like genes coordinately regulate aspects of embryonic development. Genes Dev 3: 1657–1658, 1989
    • (1989) Genes Dev , vol.3 , pp. 1657-1658
    • Lyons, KM1    Pelton, RW2    Hogan, BL3
  • 32
    • 0024991197 scopus 로고
    • Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein‐2A (BMP‐2A)
    • 32 Lyons KM, Pelton RW, Hogan BLM: Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein‐2A (BMP‐2A). Development 109: 833–844, 1990
    • (1990) Development , vol.109 , pp. 833-844
    • Lyons, KM1    Pelton, RW2    Hogan, BLM3
  • 33
    • 0026750213 scopus 로고
    • Receptors for the TGF‐ β family
    • 33 Massague J: Receptors for the TGF‐ β family. Cell 69: 1067–1070, 1992
    • (1992) Cell , vol.69 , pp. 1067-1070
    • Massague, J1
  • 34
    • 0028103179 scopus 로고
    • Sex steroid enhancement of matrix production by chondrocytes is sex and cell maturation specific
    • 34 Nasatzky E, Schwartz Z, Soskolne WA, Brooks BP, Dean DD. Boyan BD, Ornoy A: Sex steroid enhancement of matrix production by chondrocytes is sex and cell maturation specific. Endocr J 2: 207–215, 1994
    • (1994) Endocr , vol.2 , pp. 207-215
    • Nasatzky, E1    Schwartz, Z2    Soskolne, WA3    Brooks, BP4    Dean, DD5    Boyan, BD6    Ornoy, A7
  • 36
    • 0023919013 scopus 로고
    • Effects of transforming growth factor‐β on matrix synthesis by chick growth plate chondrocytes
    • 36 O'Keefe RJ, Puzas JE, Brand JS, Rosier RN: Effects of transforming growth factor‐β on matrix synthesis by chick growth plate chondrocytes. Endocrinology 122: 2953–2961, 1988
    • (1988) Endocrinology , vol.122 , pp. 2953-2961
    • O'Keefe, RJ1    Puzas, JE2    Brand, JS3    Rosier, RN4
  • 37
    • 0015228599 scopus 로고
    • Use of a mixture of proteinasefree collagenases for the specific assay of radioactive collagen in the presence of other proteins
    • 37 Peterkofsky B, Diegelmann R: Use of a mixture of proteinasefree collagenases for the specific assay of radioactive collagen in the presence of other proteins. Biochemistry 10: 988–994, 1971
    • (1971) Biochemistry , vol.10 , pp. 988-994
    • Peterkofsky, B1    Diegelmann, R2
  • 38
    • 0018609856 scopus 로고
    • Comparison of the effects of a potent synthetic analog of bovine parathyroid hormone with native bPTH‐(l‐84) and synthetic bPTH‐(l‐34) on bone resorption and collagen synthesis
    • 38 Raisz LG. Lorenzo J. Gworek S, Kream B, Rosenblatt M: Comparison of the effects of a potent synthetic analog of bovine parathyroid hormone with native bPTH‐(l‐84) and synthetic bPTH‐(l‐34) on bone resorption and collagen synthesis. Calcif Tissue Int 29: 215–218, 1979
    • (1979) Calcif Tissue Int , vol.29 , pp. 215-218
    • Raisz, LG1    Lorenzo, J2    Gworek, S3    Kream, B4    Rosenblatt, M5
  • 39
    • 0027749078 scopus 로고
    • Development of immortalized cells derived from 13DPC mouse limb buds as a system to study the effects of recombinant human bone morphogenetic protein‐2 (rhBMP‐2) on limb bud cell differentiation
    • 39 Rosen V, Capparella J, McQuaid D, Cox K, Thies RS, Song J, Wozney J: Development of immortalized cells derived from 13DPC mouse limb buds as a system to study the effects of recombinant human bone morphogenetic protein‐2 (rhBMP‐2) on limb bud cell differentiation. Prog Clin Biol Res 383: 305–315 1993
    • (1993) Prog Clin Biol Res , vol.383 , pp. 305-315
    • Rosen, V1    Capparella, J2    McQuaid, D3    Cox, K4    Thies, RS5    Song, J6    Wozney, J7
  • 40
    • 0004136246 scopus 로고
    • Molecular Cloning A Laboratory Manual
    • 40 Sambrook J, Fritsch EF, Maniatis T [eds]: Molecular Cloning A Laboratory Manual, 2nd ed. Cold Spring Harbor, New York, Cold Spring Harbor Laboratory Press, 1989
    • (1989)
  • 41
    • 0025323376 scopus 로고
    • Bovine osteogenic protein is composed of dimers of OP‐1 and BMP 2A, two members of the transforming growth factor‐β Superfamily
    • 41 Sampath TK, Coughlin JE, Whetstone RM, Banach D, Corbett C, Ridge RJ, Ozkaynak E, Oppermann H, Rueger DC: Bovine osteogenic protein is composed of dimers of OP‐1 and BMP 2A, two members of the transforming growth factor‐β Superfamily. J Biol Chem 265: 13198–13205, 1990
    • (1990) J Biol Chem , vol.265 , pp. 13198-13205
    • Sampath, TK1    Coughlin, JE2    Whetstone, RM3    Banach, D4    Corbett, C5    Ridge, RJ6    Ozkaynak, E7    Oppermann, H8    Rueger, DC9
  • 42
    • 0021337483 scopus 로고
    • Bone morphogenetic protein‐induced cartilage development in tissue culture
    • 42 Sato K, Urist MR: Bone morphogenetic protein‐induced cartilage development in tissue culture. Clin Orthop 183: 180–187, 1984
    • (1984) Clin Orthop , vol.183 , pp. 180-187
    • Sato, K1    Urist, MR2
  • 43
    • 0023819090 scopus 로고
    • Localization of vitamin D3‐responsive alkaline phosphatase in cultured chondrocytes
    • 43 Schwartz Z, Knight G, Swain LD, Boyan BD: Localization of vitamin D 3 ‐responsive alkaline phosphatase in cultured chondrocytes. J Biol Chem 263: 6023–6026, 1988
    • (1988) J Biol Chem , vol.263 , pp. 6023-6026
    • Schwartz, Z1    Knight, G2    Swain, LD3    Boyan, BD4
  • 44
    • 0024516124 scopus 로고
    • Effects of vitamin D metabolites on collagen production and cell proliferation of growth zone and resting zone carnlage cells in vitro
    • 44 Schwartz Z, Schlader DL, Ramirez V, Kennedy, MB, Boyan BD: Effects of vitamin D metabolites on collagen production and cell proliferation of growth zone and resting zone carnlage cells in vitro. J Bone Miner Res 4: 199–207, 1989
    • (1989) J Bone Miner Res , vol.4 , pp. 199-207
    • Schwartz, Z1    Schlader, DL2    Ramirez, V3    Kennedy, MB4    Boyan, BD5
  • 45
    • 0028963308 scopus 로고
    • Treatment of resting zone chondrocytes with 24,25‐dihydroxyvitamin D3 [24,25‐(OH)2D3] induces differentiation in to a 1,25‐(OH)2D3‐responsive phenotype characteristic of growth zone chondrocytes
    • 45 Schwartz Z, Dean DD, Walton JK, Brooks BP, Boyan BD: Treatment of resting zone chondrocytes with 24,25‐dihydroxyvitamin D 3 [24,25‐(OH) 2 D 3 ] induces differentiation in to a 1,25‐(OH) 2 D 3 ‐responsive phenotype characteristic of growth zone chondrocytes. Endocrinology 136: 402–411, 1995
    • (1995) Endocrinology , vol.136 , pp. 402-411
    • Schwartz, Z1    Dean, DD2    Walton, JK3    Brooks, BP4    Boyan, BD5
  • 46
    • 0029018088 scopus 로고
    • Dexamethasone promotes von Kossa‐positive nodule formation and increased alkaline phosphatase activity in costochondral chondrocyte cultures
    • 46 Schwartz Z, Hancock RH, Dean DD, Brooks BP, Gomez R, Boskey AL, Balian G, Boyan BD: Dexamethasone promotes von Kossa‐positive nodule formation and increased alkaline phosphatase activity in costochondral chondrocyte cultures Endocr J 3: 351–360, 1995
    • (1995) Endocr J , vol.3 , pp. 351-360
    • Schwartz, Z1    Hancock, RH2    Dean, DD3    Brooks, BP4    Gomez, R5    Boskey, AL6    Balian, G7    Boyan, BD8
  • 47
    • 0019983146 scopus 로고
    • The reaction of the dura to bone morphogenetic protein (BMP) in repair of skull defects
    • 47 Takagi K, Urist MR: The reaction of the dura to bone morphogenetic protein (BMP) in repair of skull defects. Ann Surg 196: 100–109, 1982
    • (1982) Ann Surg , vol.196 , pp. 100-109
    • Takagi, K1    Urist, MR2
  • 48
    • 85120519957 scopus 로고    scopus 로고
    • Role of BMP‐2 on synthesis and degradation of collagen (abstract no. 1951)
    • 48 Takiguchi T, Kobayashi M, Suzuki R, Yamaguchi A, Nagumo M, Hasega K: Role of BMP‐2 on synthesis and degradation of collagen (abstract no. 1951), J Dent Res 75 (Special Issue): 261, 1996
    • (1996) J Dent Res , vol.75 , Issue.Special Issue , pp. 261
    • Takiguchi, T1    Kobayashi, M2    Suzuki, R3    Yamaguchi, A4    Nagumo, M5    Hasega, K6
  • 49
    • 34250019537 scopus 로고
    • Bone: formation by autoinduction
    • 49 Urist MR: Bone: formation by autoinduction. Science 150: 893–899, 1965
    • (1965) Science , vol.150 , pp. 893-899
    • Urist, MR1
  • 50
    • 0024389202 scopus 로고
    • Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin
    • 50 Vukicevic S, Luyten FP, Reddi AH: Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin. Proc Natl Acad Sci USA 86: 8793–8797, 1989
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 8793-8797
    • Vukicevic, S1    Luyten, FP2    Reddi, AH3
  • 51
    • 0028290870 scopus 로고
    • Developing human lung and kidney are major sites for synthesis of bone morphogenetic protein‐3 (osteogenin)
    • 51 Vukicevic S, Helder MN, Luyten FP: Developing human lung and kidney are major sites for synthesis of bone morphogenetic protein‐3 (osteogenin). J Histochem Cytochem 42: 869–875, 1994
    • (1994) J Histochem Cytochem , vol.42 , pp. 869-875
    • Vukicevic, S1    Helder, MN2    Luyten, FP3
  • 52
    • 0027185702 scopus 로고
    • Bone morphogenetic protein‐2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells
    • 52 Wang EA, Israel DI, Kelly S, Luxenberg DP: Bone morphogenetic protein‐2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells. Growth Factors 9: 57–71, 1993
    • (1993) Growth Factors , vol.9 , pp. 57-71
    • Wang, EA1    Israel, DI2    Kelly, S3    Luxenberg, DP4
  • 54
    • 0000690015 scopus 로고
    • BMP‐2 induces differentiation of a non‐osteogenic fibroblastic cell line (C3H10T1/2) into both osteoblasts and chondroblasts in vitro
    • 54 Yamaguchi A, Ikeda T, Katagiri T, Suda T, Yoshiki S: BMP‐2 induces differentiation of a non‐osteogenic fibroblastic cell line (C3H10T1/2) into both osteoblasts and chondroblasts in vitro. Bone Miner 175: 191, 1992
    • (1992) Bone Miner , vol.175 , pp. 191
    • Yamaguchi, A1    Ikeda, T2    Katagiri, T3    Suda, T4    Yoshiki, S5
  • 55
    • 85120513754 scopus 로고    scopus 로고
    • The effects of rhBMP‐2 on cultured human periodontal ligament cells (abstract no. 1950)
    • 55 Yoshida N, Sugiyama E, Morotome Y, Duarte WR, Kasugai S, Ohya K, Ishikawa I: The effects of rhBMP‐2 on cultured human periodontal ligament cells (abstract no. 1950). J Dent Res 75 (Special Issue): 261, 1996
    • (1996) J Dent Res , vol.75 , Issue.Special Issue , pp. 261
    • Yoshida, N1    Sugiyama, E2    Morotome, Y3    Duarte, WR4    Kasugai, S5    Ohya, K6    Ishikawa, I7
  • 56
    • 0025816802 scopus 로고
    • Retinoic acid modulation of mRNA levels in malignant, nontransformed, and immortalized osteoblasts
    • 56 Zhou H, Hammonds RG Jr, Findlay DM, Fuller PJ, Martin TJ, Ng KW: Retinoic acid modulation of mRNA levels in malignant, nontransformed, and immortalized osteoblasts. J Bone Miner Res 6: 767–777, 1991
    • (1991) J Bone Miner Res , vol.6 , pp. 767-777
    • Zhou, H1    Hammonds, RG2    Findlay, DM3    Fuller, PJ4    Martin, TJ5    Ng, KW6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.