Role of complement anaphylatoxin receptors (C3aR, C5aR) in the development of the rat cerebellum

Molecular Immunology

Volumn 45, Issue 14, 2008, Pages 3767-3774

  Bénard, Magalie ^a,b,c   Raoult, Emilie ^a,b   Vaudry, David ^a,b,c   Leprince, Jérome ^a,b,c   Falluel Morel, Anthony ^a,b   Gonzalez, Bruno J ^a,b   Galas, Ludovic ^b,c   Vaudry, Hubert ^a,b,c   Fontaine, Marc ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE ROUEN   (France)

^c Regional Platform for Cell Imaging (PRIMACEN)   (France)

Author keywords

Anaphylatoxin; Cerebellum; Complement; Development

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ANAPHYLATOXIN RECEPTOR; C3AR STIMULATING AGENT; C5AR BLOCKING AGENT; PROTEIN C3AR; PROTEIN C5AR; RECEPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN DEVELOPMENT; BRAIN SIZE; CELL CULTURE; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CEREBELLUM CORTEX; CONTROLLED STUDY; GRANULE CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ANAPHYLATOXINS; ANIMALS; APOPTOSIS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CEREBELLUM; IMMUNOHISTOCHEMISTRY; NEURONS; RATS; RATS, WISTAR; RECEPTOR, ANAPHYLATOXIN C5A; RECEPTORS, COMPLEMENT; RECEPTORS, G-PROTEIN-COUPLED;

RATTUS;

EID: 48049098994     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.05.027     Document Type: Article

References (37)

1. Bénard M., Gonzalez B.J., Schouft M.T., Falluel-Morel A., Vaudry D., Chan P., Vaudry H., and Fontaine M. Characterization of C3a and C5a receptors in rat cerebellar granule neurons during maturation: neuroprotective effect of C5a against apoptotic cell death. J. Biol. Chem. 279 (2004) 43487-43496
2. Davoust N., Jones J., Stahel P.F., Ames R.S., and Barnum S.R. Receptor for the C3a anaphylatoxin is expressed by neurons and glial cells. Glia 26 (1999) 201-211
3. Dempsey P.W., Allison M.E., Akkaraju S., Goodnow C.C., and Fearon D.T. C3d of complement as a molecular adjuvant: bridging innate and acquired immunity. Science 271 (1996) 348-350
4. Ember J.A., Jagels M.A., and Hugli T.E. Characterization of complement anaphylatoxins and their biological responses. In: Volanakis J.E., and Frank M. (Eds). The Human Complement System in Health and Disease (1998), Marcel Dekker Inc., New York, USA 241-284
5. Falluel-Morel A., Vaudry D., Aubert N., Galas L., Bénard M., Basille M., Fontaine M., Fournier A., Vaudry H., and Gonzalez B.J. Pituitary adenylate cyclase-activating polypeptide prevents the effects of ceramides on migration, neurite outgrowth, and cytoskeleton remodeling. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 2637-2642
6. Farkas I., Baranyi L., Liposits Z.S., Yamamoto T., and Okada H. Complement C5 anaphylatoxin fragment causes apoptosis in TGW neuroblastoma cells. Neuroscience 86 (1998) 903-911
7. Farkas I., Takahashi M., Fukuda A., Yamamoto N., Akatsu H., Baranyi L., Tateyama H., Yamamoto T., Okada N., and Okada H. Complement C5a receptor-mediated signaling may be involved in neurodegeneration in Alzheimer's disease. J. Immunol. 170 (2003) 5764-5771
8. Finch A.M., Wong A.K., Paczkowski N.J., Wadi S.K., Craik D.J., Fairlie D.P., and Taylor S.M. Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a. J. Med. Chem. 42 (1999) 1965-1974
9. Gasque P., Singhrao S.K., Neal J.W., Gotze O., and Morgan B.P. Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system. Am. J. Pathol. 150 (1997) 31-41
10. Gonzalez B.J., Leroux P., Lamacz M., Bodenant C., Balazs R., and Vaudry H. Somatostatin receptors are expressed by immature cerebellar granule cells: evidence for a direct inhibitory effect of somatostatin on neuroblast activity. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 9627-9631
11. Ischenko A., Sayah S., Patte C., Andreev S., Gasque P., Schouft M.T., Vaudry H., and Fontaine M. Expression of a functional anaphylatoxin C3a receptor by astrocytes. J. Neurochem. 71 (1998) 2487-2496
12. Jauneau A.C., Ischenko A., Chan P., and Fontaine M. Complement component anaphylatoxins upregulate chemokine expression by human astrocytes. FEBS Lett. 537 (2003) 17-22
13. Kimura Y., Madhavan M., Call M.K., Santiago W., Tsonis P.A., Lambris J.D., and Del Rio-Tsonis K. Expression of complement 3 and complement 5 in new limb and lens regeneration. J. Immunol. 170 (2003) 2331-2339
14. Lacy M., Jones J., Whittemore S.R., Haviland D.L., Wetsel R.A., and Barnum S.R. Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia. J. Neuroimmunol. 61 (1995) 71-78
15. Liszewski M.K., Kemper C., Price J.D., and Atkinson J.P. Emerging roles and new functions of CD46. Springer Semin. Immunopathol. 27 (2005) 345-358
16. Mastellos D., Papadimitriou J.C., Franchini S., Tsonis P.A., and Lambris J.D. A novel role of complement: mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration. J. Immunol. 166 (2001) 2479-2486
17. Mastellos D., and Lambris J.D. Complement: more than a 'guard' against invading pathogens?. Trends Immunol. 23 (2002) 485-491
18. Mukherjee P., and Pasinetti G.M. The role of complement anaphylatoxin C5a in neurodegeneration: implications in Alzeimer's disease. J. Neuroimmunol. 105 (2000) 124-130
19. Müller-Ladner U., Jones J.L., Wetsel R.A., Gay S., Raine C., and Barnum S.R. Enhanced expression of chemotactic receptors in multiple sclerosis lesions. J. Neurol. Sci. 144 (1996) 135-141
20. Nadarajah B., and Parnavelas J.G. Modes of neuronal migration in the developing cerebral cortex. Nat. Rev. Neurosci. 3 (2002) 423-432
21. Nataf S., Davoust N., and Barnum S. Kinetics of anaphylatoxin C5a receptor expression during experimental allergic encephalomyelitis. J. Neuroimmunol. 91 (1998) 147-155
22. O'Barr S.A., Caguioa J., Gruol D., Perkins G., Ember J.A., Hugli T., and Cooper N.R. Neuronal expression of a functional receptor for the C5a complement activation fragment. J. Immunol. 166 (2001) 4154-4162
23. Oomman S., Strahlendorf H., Dertien J., and Strahlendorf J. Bergmann glia utilizes active caspase-3 for differentiation. Brain Res. 1078 (2006) 19-34
24. Osaka H., Mukherjee P., Aisen P.S., and Pasinetti G.M. Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity. J. Cell. Biochem. 73 (1999) 303-311
25. Rakic P. Neuron-glia relationship during granule cell migration in developing cerebellar cortex: a Golgi and electronmicroscopic study in Macacus rhesus. J. Comp. Neurol. 141 (1971) 283-312
26. Raphpeymai Y., Hietala M.A., Wilhelmsson U., Fotheringham A., Davies I., Nilsson A.K., Zwirner J., Wetsel R.A., Gerard C., Pekny M., and Pekna M. Complement: a novel factor in basal and ischemia-induced neurogenesis. EMBO J. 25 (2006) 1364-1374
27. Sato T., Abe E., Jin C.H., Hong M.H., Katagiri T., Kinoshita T., Amizuka N., Ozawa H., and Suda T. The biological roles of the third component of complement in osteoclast formation. Endocrinology 133 (1993) 397-404
28. Sayah S., Ischenko A.M., Zhakhov A., Bonnard A.S., and Fontaine M. Expression of cytokines by human astrocytomas following stimulation by C3a and C5a anaphylatoxins: specific increase in interleukin-6 mRNA expression. J. Neurochem. 72 (1999) 2426-2436
29. Sottile V., Li M., and Scotting P.J. Stem cell marker expression in the Bergmann glia population of the adult mouse brain. Brain Res. 1099 (2006) 8-17
30. Stahel P.F., Frei K., Eugster H.P., Fontana A., Hummel K.M., Wetsel R.A., Ames R.S., and Barnum S.R. TNFα mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalis. J. Immunol. 159 (1997) 861-869
31. Stahel P.F., Kossmann T., Morganti-Kossmann M.C., Hans V.H.J., and Barnum S.R. Experimental diffuse axonal injury induces neuronal C5a receptor mRNA expression in rats. Mol. Brain Res. 50 (1997) 205-212
32. Stevens B., Allen N.J., Vazquez L.E., Howell G.R., Christopherson K.S., Nouri N., Micheva K.D., Mehalow A.K., Huberman A.D., Stafford B., Sher A., Litke A.M., Lambris J.D., Smith S.J., John S.W.M., and Barres B.A. The classical complement cascade mediates CNS synapse elimination. Cell 131 (2007) 1164-1178
33. Strey C.W., Markiewshi M.M., Mastellos D., Tudoran R., Spruce L.A., Greenbaum L.E., and Lambris J.D. The proinflammatory mediators C3a and C5a are essential for liver regeneration. J. Exp. Med. 198 (2003) 913-923
34. Van Beek J., Nicole O., Ali C., Ischenko A., MacKenzie E.T., Buisson A., and Fontaine M. Complement anaphylatoxin C3a is selectively protective against NMDA-induced neuronal cell death. Neuroreport 12 (2001) 289-293
35. Vaudry D., Gonzalez B.J., Basille M., Fournier A., and Vaudry H. Neurotrophic activity of pituitary adenylate cyclase-activating polypeptide on rat cerebellar cortex during development. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 9415-9420
36. Volanakis J.E. Overview of the complement system. In: Volanakis J.E., and Frank M. (Eds). The Human Complement System in Health and Disease (1998), Marcel Dekker Inc., New York, USA 9-32
37. Woodruff T.M., Crane J.W., Proctor L.M., Buller K.M., Shek A.B., De Vos K., Pollitt S., Williams H.M., Shiels I.A., Monk P.N., and Taylor S.M. Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration. FASEB J. 20 (2006) 1407-1417