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Volumn 60, Issue 8, 2008, Pages 1089-1095

Inflammatory factors that contribute to upregulation of ERG and cardiac arrhythmias are suppressed by CPU86017, a class III antiarrhythmic agent

Author keywords

[No Author keywords available]

Indexed keywords

ANTIARRHYTHMIC AGENT; BERBERINE; CATALASE; CPU 86017; ENDOTHELIN; ENDOTHELIN CONVERTING ENZYME; GLUTATHIONE PEROXIDASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; POTASSIUM CHANNEL HERG; PREPROENDOTHELIN 1; PROPRANOLOL; REACTIVE OXYGEN METABOLITE; THYROXINE; TRANSFORMING GROWTH FACTOR BETA;

EID: 47949124092     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.60.8.0015     Document Type: Article
Times cited : (6)

References (39)
  • 1
    • 0030602898 scopus 로고    scopus 로고
    • Membrane stabilizing, anti-oxidative interactions of propranolol and dexpropranolol with neutrophils
    • Anderson, R., Ramafi, G., Theron, A. J. (1996) Membrane stabilizing, anti-oxidative interactions of propranolol and dexpropranolol with neutrophils. Biochem. Pharmacol. 52: 341-349
    • (1996) Biochem. Pharmacol , vol.52 , pp. 341-349
    • Anderson, R.1    Ramafi, G.2    Theron, A.J.3
  • 2
    • 33749039447 scopus 로고    scopus 로고
    • Congenital long QT syndrome: Diagnosis and management in pediatric patients
    • Bar-Cohen, Y., Silka, M. J. (2006) Congenital long QT syndrome: diagnosis and management in pediatric patients. Curr. Treat. Options Cardiovasc. Med. 8: 387-395
    • (2006) Curr. Treat. Options Cardiovasc. Med , vol.8 , pp. 387-395
    • Bar-Cohen, Y.1    Silka, M.J.2
  • 3
    • 24644506605 scopus 로고    scopus 로고
    • Extraction of RNA from cells and tissue
    • Bird, I. M. (2005) Extraction of RNA from cells and tissue. Methods Mol. Med. 108: 139-148
    • (2005) Methods Mol. Med , vol.108 , pp. 139-148
    • Bird, I.M.1
  • 4
    • 33644815940 scopus 로고    scopus 로고
    • The short QT syndrome as a paradigm to understand the role of potassium channels in ventricular fibrillation
    • Cerrone, M., Noujaim, S., Jalife, J. (2006) The short QT syndrome as a paradigm to understand the role of potassium channels in ventricular fibrillation. J. Intern. Med. 259: 24-38
    • (2006) J. Intern. Med , vol.259 , pp. 24-38
    • Cerrone, M.1    Noujaim, S.2    Jalife, J.3
  • 5
    • 0028914969 scopus 로고
    • A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
    • Curran, M. E., Splawski, I., Timothy, K. W., Vincent, G. M., Green, E. D., Keating, M. T. (1995) A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome. Cell 80: 795-803
    • (1995) Cell , vol.80 , pp. 795-803
    • Curran, M.E.1    Splawski, I.2    Timothy, K.W.3    Vincent, G.M.4    Green, E.D.5    Keating, M.T.6
  • 6
    • 33847652782 scopus 로고    scopus 로고
    • CPU-86017: A novel Class III antiarrhythmic agent with multiple actions at ion channels
    • Dai, D. Z. (2006) CPU-86017: a novel Class III antiarrhythmic agent with multiple actions at ion channels. Cardiovasc. Drug. Rev. 24: 101-115
    • (2006) Cardiovasc. Drug. Rev , vol.24 , pp. 101-115
    • Dai, D.Z.1
  • 7
    • 23844466964 scopus 로고    scopus 로고
    • Ion channelopathy and hyperphosphorylation contributing to cardiac arrhythmias
    • Dai, D. Z., Yu, F. (2005) Ion channelopathy and hyperphosphorylation contributing to cardiac arrhythmias. Acta. Pharmacol. Sin. 26: 918-925
    • (2005) Acta. Pharmacol. Sin , vol.26 , pp. 918-925
    • Dai, D.Z.1    Yu, F.2
  • 8
    • 1842759623 scopus 로고    scopus 로고
    • Blockade of L-type calcium channel in myocardium and calcium-induced contractions of vascular smooth muscle by CPU 86017
    • Dai, D. Z., Hu, H. J., Zhao, J., Hao, X. M., Yang, D. M., Zhou, P. A., Wu, C. H. (2004) Blockade of L-type calcium channel in myocardium and calcium-induced contractions of vascular smooth muscle by CPU 86017. Acta. Pharmacol. Sin. 25: 416-423
    • (2004) Acta. Pharmacol. Sin , vol.25 , pp. 416-423
    • Dai, D.Z.1    Hu, H.J.2    Zhao, J.3    Hao, X.M.4    Yang, D.M.5    Zhou, P.A.6    Wu, C.H.7
  • 9
    • 21844437396 scopus 로고    scopus 로고
    • CPU-86017 improves the compromised blood-brain barrier permeability mediated by impaired endothelial NO system and oxidative stress caused by L-Thyroxin
    • Du, R. H., Cibangu, D. C., Dai, D. Z., Lin, S., Guan, L. (2005) CPU-86017 improves the compromised blood-brain barrier permeability mediated by impaired endothelial NO system and oxidative stress caused by L-Thyroxin. Drug Dev. Res. 64: 145-156
    • (2005) Drug Dev. Res , vol.64 , pp. 145-156
    • Du, R.H.1    Cibangu, D.C.2    Dai, D.Z.3    Lin, S.4    Guan, L.5
  • 10
    • 35649003917 scopus 로고    scopus 로고
    • Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors
    • Feng, Y., Tang, X. Y., Dai, D. Z., Dai, Y. (2007a) Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors. Acta Pharmacol. Sin. 28: 1746-1754
    • (2007) Acta Pharmacol. Sin , vol.28 , pp. 1746-1754
    • Feng, Y.1    Tang, X.Y.2    Dai, D.Z.3    Dai, Y.4
  • 11
    • 34548128787 scopus 로고    scopus 로고
    • Endothelin receptor antagonist CPU0213 suppresses ventricular fibrillation in L-thyroxin induced cardiomyopathy
    • Feng, Y., Dai, D. Z., Na, T., Cui, B., Wang, T., Zhang, Y., Dai, Y. (2007b) Endothelin receptor antagonist CPU0213 suppresses ventricular fibrillation in L-thyroxin induced cardiomyopathy. Pharmacol. Rep. 59: 306-14
    • (2007) Pharmacol. Rep , vol.59 , pp. 306-314
    • Feng, Y.1    Dai, D.Z.2    Na, T.3    Cui, B.4    Wang, T.5    Zhang, Y.6    Dai, Y.7
  • 12
    • 39849092319 scopus 로고    scopus 로고
    • Gallagher, S.R. (2006) One-dimensional SDS gel electrophoresis of proteins. Curr. Protoc. Mol. Biol. 10: 10.2A
    • Gallagher, S.R. (2006) One-dimensional SDS gel electrophoresis of proteins. Curr. Protoc. Mol. Biol. 10: 10.2A
  • 14
    • 33745787930 scopus 로고    scopus 로고
    • Antioxidants and inflammatory disease: Synthetic and natural antioxidants with anti-inflammatory activity
    • Geronikaki, A. A., Gavalas, A. M. (2006) Antioxidants and inflammatory disease: synthetic and natural antioxidants with anti-inflammatory activity. Comb. Chem. High Throughput Screen. 9: 425-442
    • (2006) Comb. Chem. High Throughput Screen , vol.9 , pp. 425-442
    • Geronikaki, A.A.1    Gavalas, A.M.2
  • 16
    • 27744492459 scopus 로고    scopus 로고
    • An exaggerated oxidative stress is induced in the myocardium by L-thyroxin and suppressed by CPU86017, a derivative of tetrahydroberberine
    • Hao, J. M., Dai, D. Z., Yu, F. (2005) An exaggerated oxidative stress is induced in the myocardium by L-thyroxin and suppressed by CPU86017, a derivative of tetrahydroberberine. Adv. Pharmacy (Chinese) 29: 417-421
    • (2005) Adv. Pharmacy (Chinese) , vol.29 , pp. 417-421
    • Hao, J.M.1    Dai, D.Z.2    Yu, F.3
  • 18
    • 0033734714 scopus 로고    scopus 로고
    • Bosentan the mixed endothelin-A- and -B-receptor antagonist suppresses intrapericardial endothelin-1-induced ventricular arrhythmias
    • Horkay, F., Gellér, L., Kiss, O., Szabó, T., Vagó H., Kékesi, V., Juhász-Nagy, A., Merkely, B. (2000) Bosentan the mixed endothelin-A- and -B-receptor antagonist suppresses intrapericardial endothelin-1-induced ventricular arrhythmias. J. Cardiovasc. Pharmacol. 36 (5 Suppl 1): S320-322
    • (2000) J. Cardiovasc. Pharmacol , vol.36 , Issue.5 SUPPL. 1
    • Horkay, F.1    Gellér, L.2    Kiss, O.3    Szabó, T.4    Vagó, H.5    Kékesi, V.6    Juhász-Nagy, A.7    Merkely, B.8
  • 19
    • 0344461936 scopus 로고
    • Inhibitory effect of berberine on potassium channels in guinea pig ventricular myocytes (Chinese)
    • Hua, Z., Wang, X. L. (1994) Inhibitory effect of berberine on potassium channels in guinea pig ventricular myocytes (Chinese). Yao Xue Xue Bao 29: 576-580
    • (1994) Yao Xue Xue Bao , vol.29 , pp. 576-580
    • Hua, Z.1    Wang, X.L.2
  • 20
    • 33645806742 scopus 로고    scopus 로고
    • Fibrosis in heart disease: Understanding the role of transforming growth factor-β1 in cardiomyopathy, valvular disease and arrhythmia
    • Khan, R., Sheppard, R. (2006) Fibrosis in heart disease: understanding the role of transforming growth factor-β1 in cardiomyopathy, valvular disease and arrhythmia. Immunology 118: 10-24
    • (2006) Immunology , vol.118 , pp. 10-24
    • Khan, R.1    Sheppard, R.2
  • 21
    • 34547758031 scopus 로고    scopus 로고
    • Mutation screening in KCNQ1, HERG, KCNE1, KCNE2 and SCN5A genes in a long QT syndrome family
    • Koo, S. H., Teo, W. S., Ching, C. K., Chan, S. H., Lee, E. J. (2007) Mutation screening in KCNQ1, HERG, KCNE1, KCNE2 and SCN5A genes in a long QT syndrome family. Ann. Acad. Med. Singapore 36: 394-398
    • (2007) Ann. Acad. Med. Singapore , vol.36 , pp. 394-398
    • Koo, S.H.1    Teo, W.S.2    Ching, C.K.3    Chan, S.H.4    Lee, E.J.5
  • 22
    • 0346724714 scopus 로고    scopus 로고
    • The anti-inflammatory potential of berberine in vitro and in vivo
    • Kuo, C. L., Chi, C. W., Liu, T. Y. (2004) The anti-inflammatory potential of berberine in vitro and in vivo. Cancer Lett. 203: 127-137
    • (2004) Cancer Lett , vol.203 , pp. 127-137
    • Kuo, C.L.1    Chi, C.W.2    Liu, T.Y.3
  • 25
    • 3042699908 scopus 로고    scopus 로고
    • Effects of endothelins on cardiac and vascular cells: New therapeutic target for the future?
    • Mohácsi, A., Magyar, J., Tamás, B., Nánási, P. P. (2004) Effects of endothelins on cardiac and vascular cells: new therapeutic target for the future? Curr. Vasc. Pharmacol. 2: 53-63
    • (2004) Curr. Vasc. Pharmacol , vol.2 , pp. 53-63
    • Mohácsi, A.1    Magyar, J.2    Tamás, B.3    Nánási, P.P.4
  • 26
    • 33847683001 scopus 로고    scopus 로고
    • Upregulation of leptin pathway correlates with abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure and reversal by CPU-86017
    • Na, T., Dai, D. Z., Tang, X. Y., Dai, Y. (2007) Upregulation of leptin pathway correlates with abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure and reversal by CPU-86017. Naunyn Schmiedebergs Arch. Pharmacol. 375: 39-49
    • (2007) Naunyn Schmiedebergs Arch. Pharmacol , vol.375 , pp. 39-49
    • Na, T.1    Dai, D.Z.2    Tang, X.Y.3    Dai, Y.4
  • 27
    • 0033047358 scopus 로고    scopus 로고
    • Prevention of sudden death in congenital long-QT syndrome
    • Oliveira, M., Antunes, E., da Silva, M. N. (1999) Prevention of sudden death in congenital long-QT syndrome. Rev. Port. Cardiol. 18: 627-633
    • (1999) Rev. Port. Cardiol , vol.18 , pp. 627-633
    • Oliveira, M.1    Antunes, E.2    da Silva, M.N.3
  • 28
    • 23844535600 scopus 로고    scopus 로고
    • The long QT syndrome: A clinical counterpart of hERG mutations
    • Schwartz, P. J. (2005) The long QT syndrome: a clinical counterpart of hERG mutations. Novartis. Found. Symp. 266: 186-198
    • (2005) Novartis. Found. Symp , vol.266 , pp. 186-198
    • Schwartz, P.J.1
  • 32
    • 34548308975 scopus 로고    scopus 로고
    • Leaky ryanodine receptors cause delayed afterdepolarizations and ventricular arrhythmias
    • Wehrens, X. H. (2007) Leaky ryanodine receptors cause delayed afterdepolarizations and ventricular arrhythmias. Eur. Heart J. 8: 1054-1061
    • (2007) Eur. Heart J , vol.8 , pp. 1054-1061
    • Wehrens, X.H.1
  • 33
    • 33847139443 scopus 로고    scopus 로고
    • The hERG potassium channel as a therapeutic target
    • Witchel, H. J. (2007) The hERG potassium channel as a therapeutic target. Expert. Opin. Ther. Targets 11: 321-336
    • (2007) Expert. Opin. Ther. Targets , vol.11 , pp. 321-336
    • Witchel, H.J.1
  • 34
    • 4544262570 scopus 로고    scopus 로고
    • Drugs that cause Torsades de pointes and increase the risk of sudden cardiac death
    • Wolbrette, D. L. (2004) Drugs that cause Torsades de pointes and increase the risk of sudden cardiac death. Curr. Cardiol. Rep. 6: 379-384
    • (2004) Curr. Cardiol. Rep , vol.6 , pp. 379-384
    • Wolbrette, D.L.1
  • 35
    • 33748952130 scopus 로고    scopus 로고
    • Up-regulated inflammatory factors endothelin, NFkappaB, TNFalpha and iNOS involved in exaggerated cardiac arrhythmias in 1-thyroxine-induced cardiomyopathy are suppressed by darusentan in rats
    • Xia, H. J., Dai, D. Z., Dai, Y. (2006) Up-regulated inflammatory factors endothelin, NFkappaB, TNFalpha and iNOS involved in exaggerated cardiac arrhythmias in 1-thyroxine-induced cardiomyopathy are suppressed by darusentan in rats. Life Sci. 2006; 79: 1812-1819
    • (2006) Life Sci , vol.2006 , Issue.79 , pp. 1812-1819
    • Xia, H.J.1    Dai, D.Z.2    Dai, Y.3
  • 36
    • 0030736433 scopus 로고    scopus 로고
    • Effects of berberine of L- and T-type calcium channels in guinea pig ventricular myocytes
    • Xu, S. Z., Zhang Y., Ren J. Y., Zhou Z. N. (1997) Effects of berberine of L- and T-type calcium channels in guinea pig ventricular myocytes. Zhongguo Yao Li Xue Bao 18: 515-518
    • (1997) Zhongguo Yao Li Xue Bao , vol.18 , pp. 515-518
    • Xu, S.Z.1    Zhang, Y.2    Ren, J.Y.3    Zhou, Z.N.4
  • 37
    • 0031037588 scopus 로고    scopus 로고
    • Heart hypertrophy induced by levothyroxine aggravates ischemic lesions and reperfusion arrhythmias in rats
    • Yu, F., Dai, D. Z., An, L. F., Guo, X. F. (1997) Heart hypertrophy induced by levothyroxine aggravates ischemic lesions and reperfusion arrhythmias in rats. Acta Pharmacol. Sin. 18: 71-74
    • (1997) Acta Pharmacol. Sin , vol.18 , pp. 71-74
    • Yu, F.1    Dai, D.Z.2    An, L.F.3    Guo, X.F.4
  • 38
    • 26444440760 scopus 로고    scopus 로고
    • Rapidly activating delayed rectifier K+ current in cardiomyocytes from hypertrophied guinea pig hearts induced by thyroxin
    • Zhang, G. Q., Ma, Y. P., Hao, J. M., Zhou, P. A., Wu, C. H., Dai, D. Z. (2000) Rapidly activating delayed rectifier K+ current in cardiomyocytes from hypertrophied guinea pig hearts induced by thyroxin. J. China. Pharma. Univ. 31: 451-454
    • (2000) J. China. Pharma. Univ , vol.31 , pp. 451-454
    • Zhang, G.Q.1    Ma, Y.P.2    Hao, J.M.3    Zhou, P.A.4    Wu, C.H.5    Dai, D.Z.6
  • 39
    • 33644673222 scopus 로고    scopus 로고
    • Pharmacological efficacy of CPU 86017 on hypoxic pulmonary hypertension in rats: Mediated by direct inhibition of calcium channels and antioxidant action, but indirect effects on the ET-1 pathway
    • Zhang, T. T., Cui, B., Dai, D. Z., Tang, X. Y. (2005) Pharmacological efficacy of CPU 86017 on hypoxic pulmonary hypertension in rats: mediated by direct inhibition of calcium channels and antioxidant action, but indirect effects on the ET-1 pathway. J. Cardiovasc. Pharmacol. 46: 727-734
    • (2005) J. Cardiovasc. Pharmacol , vol.46 , pp. 727-734
    • Zhang, T.T.1    Cui, B.2    Dai, D.Z.3    Tang, X.Y.4


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