Inhibition of PHF-like tau hyperphosphorylation in SH-SY5Y cells and rat brain slices by K252a

Journal of Alzheimer's Disease

Volumn 13, Issue 3, 2008, Pages 281-294

  Hübinger, Gabriele ^a   Geis, Silvia ^a   LeCorre, Sylvie ^a,d   Mühlbacher, Susanne ^a   Gordon, Sandra ^a   Fracasso, R Paul ^b   Hoffman, Fred ^b   Ferrand, Sandrine ^a   Klafki, Hans W ^a,e   Roder, Hanno M ^c,f  

^a Sirenade Pharmaceuticals AG   (Germany)

^b BAYER CORPORATION   (United States)

^c TauTaTis Inc   (United States)

^d AMO Germany GmbH   (Germany)

^e UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^f MAYO CLINIC   (United States)

Author keywords

Alzheimer's disease; ERK2 inhibitor; K252a; PHF; Tau hyperphosphorylation

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; K 252A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; OKADAIC ACID; STAUROSPORINE; TAU PROTEIN; TUBULIN;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; PAIRED HELICAL FILAMENT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; RAT; TAU HYPERPHOSPHORYLATION;

EID: 47849128898     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2008-13306     Document Type: Article

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