Vitamin E administration at the onset of fever prevents renal scarring in acute pyelonephritis

Pediatric Nephrology

Volumn 23, Issue 9, 2008, Pages 1503-1510

  Sadeghi, Zhina ^a   Kajbafzadeh, Abdol Mohammad ^a,c   Tajik, Parvin ^b   Monajemzadeh, Maryam ^b   Payabvash, Seyedmehdi ^a   Elmi, Azadeh ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c NONE   (Iran)

Author keywords

Acute pyelonephritis; Cell apoptosis; Fever; Renal scar; TGF ; Vitamin E

Indexed keywords

ALLOPURINOL; ALPHA TOCOPHEROL; ANTIBIOTIC AGENT; CEFTRIAXONE; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE PYELONEPHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC SENSITIVITY; APOPTOSIS; ARTICLE; BODY TEMPERATURE MONITORING; CONTROLLED STUDY; DRUG EFFICACY; ESCHERICHIA COLI; FEVER; HISTOPATHOLOGY; KIDNEY FIBROSIS; MALE; NEPHRITIS; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; SCAR FORMATION;

ACUTE DISEASE; ANIMALS; ANTIOXIDANTS; CICATRIX; FEVER; KIDNEY; MALE; PYELONEPHRITIS; RATS; RATS, WISTAR; TRANSFORMING GROWTH FACTOR BETA; VITAMIN E;

EID: 47749153342     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-008-0853-7     Document Type: Article

References (35)

1. Glauser MP, Meylan P, Bille J (1987) The inflammatory response and tissue damage. Pediatr Nephrol 1:615-619
2. Roberts JA, Kaack MB, Baskin G (1990) Treatment of experimental pyelonephritis in the monkey. J Urol 143:150-154
3. Pohl HG, Rushton HG, Park J, Chandra R, Majd M (1999) Adjunctive oral corticosteroids reduce renal scarring: The piglet model of reflux and acute experimental pyelonephritis. J Urol 162:815-820
4. Garin EH, Olavarria F, Garcia Nieto V, Valenciano B, Campos A, Young L (2006) Clinical significance of primary vesicoureteral reflux and urinary antibiotic prophylaxis after acute pyelonephritis: A multicenter, randomized, controlled study. J Pediatr 117:626-632
5. Haraoka M, Matsumoto T, Takahashi K, Kubo S, Tanaka M, Kumazawa J (1994) Suppression of renal scarring by prednisolone combined with ciprofloxacin in ascending pyelonephritis in rats. J Urol 151:1078-1080
6. Huang A, Palmer LS, Hom D, Anderson AE, Leslie K, Israel F (1999) Ibuprofen combined with antibiotics suppresses renal scarring due to ascending pyelonephritis in rats. J Urol 162:1396-1398
7. LeBrun M, Grenier L, Gourde P, Bergeron MG, Labrecque G, Beauchamp D (1999) Effectiveness and toxicity of gentamicin in an experimental model of pyelonephritis: Effect of the time of administration. Antimicrob Agents Chemother 43:1020-1026
8. Kavukcu S, Soylu A, Turkmen M, Sarioglu S, Buyukgebiz B, Gure A (1999) The role of vitamin A in preventing renal scarring secondary to pyelonephritis. BJU Int 83:1055-1059
9. McLorie GA, McKenna PH, Jumper BM (1990) High grade vesicourethral reflux: Analysis of observational therapy. J Urol 144:537-545
10. Roberts JA, Kaack MB, Fussell EN, Baskin G (1986) Immunology of pyelonephritis VII. Effect of allopurinol. J Urol 136:660-663
11. Singal AK, Bajpai M, Dinda AK (2005) Blockade of rennin-angiotensin system blunts the fibrotic response in experimental acute pyelonephritis. J Indian Assoc Pediatr Surg 10:20-24
12. Yagmurlu A, Boleken ME, Etory D, Ozsan M, Gokcora IH, Dindar H (2003) Preventive effect of pentoxifylline on renal scarring in rat model of pyelonephritis. J Urol 61:1037-1041
13. Bennett RT, Mazzaccaro RJ, Chopra N, Melman A, Israel F (1999) Suppression of renal inflammation with vitamin A and E in ascending pyelonephritis in rats. J Urol 161:1681-1684
14. Serlachius E, Sundelin B, Eklöf AC, Jahnke M, Laestadius A, Aperia A (1997) Pyelonephritis provokes growth retardation and apoptosis in infant rat renal cortex. Kidney Int 51:1855-1862
15. Kannan K, Jain SK (2000) Oxidative stress and apoptosis. Pathophysiology 7:153-163
16. Zhang D, Okada S, Yu Y, Zheng P, Yamaguchi R, Kasai H (1997) Vitamin E inhibits apoptosis, DNA modification, and cancer incidence induced by iron-mediated peroxidation in Wistar rat kidney. Cancer Res 57:2410-2414
17. Kaye D (1971) The effect of water diuresis on spread of bacteria through the urinary tract. J Infect Dis 124:297-305
18. Yasunaga Y, Kato H, Ohgaki K, Inamoto T, Hikasa Y (1982) Effect of vitamin E as an immunopotentiation agent for mice at optimal dosage and its toxicity at high dosage. J Nutr 112:1075-1084
19. Payabvash S, Kajbafzadeh A, Tavangar S, Monajemzadeh M, Sadeghi Z (2007) Myocyte apoptosis in primary obstructive megaureters: The role of decreased vascular and neural supply. J Urol 178:259-264
20. Chiou YY, Wang ST, Tang MJ, Lee BF, Chiu NT (2001) Renal fibrosis: prediction from acute pyelonephritis focus volume measured at 99mTc dimercaptosuccinic acid SPECT. Radiology 221:366-370
21. Fretzayas A, Moustaki M, Gourgiotis D, Bossios A, Koukoutsakis P, Stavrinadis C (2000) Polymorphonuclear elastase as a diagnostic marker of acute pyelonephritis in children. J Pediatr 105:28-35
22. Pecile P, Miorin E, Romanello C, Falleti E, Valent F, Giacomuzzi F, Tenore A (2004) Procalcitonin: A marker of severity of acute pyelonephritis among children. J Pediatr 114:249-254
23. Pinson AG, Philbrick JT, Lindbeck GH, Schorling JB (1997) Fever in the clinical diagnosis of acute pyelonephritis. Am J Emerg Med 15:148-151
24. Lin KY, Chiu NT, Chen MJ, Lai CH, Huang JJ, Wang YT, Chiou YY (2004) Acute pyelonephritis and sequelae of renal scar in pediatric first febrile urinary tract infection. Pediatr Nephrol 18:362-365
25. Glauser MP, Lyons JM, Braude AI (1978) Prevention of chronic experimental pyelonephritis by suppression of acute suppuration. J Clin Invest 61:403-407
26. Imamoglu M, Cay A, Cobanoglu U, Bahat E, Karahan C, Tosun I, Sarhan H (2006) Effects of melatonin on suppression of renal scarring in experimental model of pyelonephritis. J Urol 67:1315-1319
27. Matsumoto T, Mitzunoe Y, Ogata N, Tanaka M, Takahashi K, Kumazawa J (1992) Antioxidant effect on renal scarring following infection of mannose-sensitive-piliated bacteria. Nephron 60:210-214
28. Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM (1998) Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 101:890-898
29. Canbay A, Friedman S, Gores GJ (2004) Apoptosis: The nexus of liver injury and fibrosis. Hepatology 39:273-278
30. Fliss H, Gattinger D (1996) Apoptosis in ischemic and reperfused rat myocardium. Circ Res 79:949-956
31. Jakobsson B, Nolstedt L, Svensson L, Söderlundh S, Berg U (1992) 99 m Technetium dimercaptosuccinic acid scan in the diagnosis of acute pyelonephritis in children: Relation to clinical and radiological findings. Pediatr Nephrol 6:328-334
32. Kucuk HF, Bingul SM, Kurt N, Kaptanoglu L, Akyol H, Torlak OA, Colak E (2006) Effect of a selective cyclooxygenase-2 inhibitor on renal scarring. Eur Surg Res 38:451-457
33. Melis K, Vandevivere J, Hoskens C, Vervaet A, Sand A, Van Acker KJ (1992) Involvement of the renal parenchyma in acute urinary tract infection: The contribution of 99mTc-dimercaptosuccinic acid scan. Eur J Pediatr 151:536-539
34. Rushton HG, Belman AB (1968) Vesicoureteral reflux and renal scarring. In: Holliday MA (ed) 3rd edn. Williams & Wilkins, Baltimore, pp 963-985
35. Verboven M, Ingels M, Delree M, Piepsz A (1990) 99mTc-DMSA scintigraphy in acute urinary tract infection in children. Pediatr Radiol 20:540-542