Antibody-onconase conjugates: Cytotoxicity and intracellular routing

Current Pharmaceutical Biotechnology

Volumn 9, Issue 3, 2008, Pages 226-230

  Rybak, Susanna M ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Bionanomics LLC   (United States)

Author keywords

Antibody; Immunotoxin; Internalization; Onconase; Ribonuclease; RNase A

Indexed keywords

ANTIBODY; CD22 ANTIBODY; CELL ANTIBODY; DISULFIDE; IMMUNOTOXIN; MONOCLONAL ANTIBODY MRK 16; PANCREATIC RIBONUCLEASE; RANPIRNASE; RECEPTOR ANTIBODY; RIBONUCLEASE A; SULFIDE; TRANSFERRIN; TRANSFERRIN RECEPTOR; UNTRANSLATED RNA;

ANTIGEN RECOGNITION; ANTINEOPLASTIC ACTIVITY; CANCER CELL; CELL DEATH; CLINICAL TRIAL; CYTOSOL; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG FORMULATION; DRUG POTENCY; DRUG SPECIFICITY; DRUG TARGETING; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; INTERNALIZATION; LYSOSOME; MESOTHELIOMA; NONHUMAN; PROTEIN FAMILY; REVIEW; TUMOR CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD22; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; HUMANS; IMMUNOCONJUGATES; MICROBIAL SENSITIVITY TESTS; NEOPLASMS; P-GLYCOPROTEIN; RECEPTORS, TRANSFERRIN; RIBONUCLEASES;

MUS;

EID: 47749146908     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920108784567272     Document Type: Review

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