The eer5 mutation, which affects a novel proteasome-related subunit, indicates a prominent role for the COP9 signalosome in resetting the ethylene-signaling pathway in Arabidopsis

Plant Journal

Volumn 55, Issue 3, 2008, Pages 467-477

  Christians, Matthew J ^a   Robles, Linda M ^a   Zeller, Samantha M ^a   Larsen, Paul B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Arabidopsis; COP9; CSN; EER5; EIN2; Ethylene

Indexed keywords

ARABIDOPSIS PROTEIN; CELL SURFACE RECEPTOR; CONSTITUTIVE PHOTOMORPHOGENIC 9 PROTEIN, ARABIDOPSIS; EER5 PROTEIN, ARABIDOPSIS; EIN2 PROTEIN, ARABIDOPSIS; ETHYLENE; ETHYLENE DERIVATIVE; PROTEASOME;

ARABIDOPSIS; ARTICLE; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; METABOLISM; MUTATION; PHENOTYPE; PHYSIOLOGY; PLANT GROWTH; PROTEIN ANALYSIS; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; ETHYLENES; GENE EXPRESSION REGULATION, PLANT; GENOTYPE; HYPOCOTYL; MUTATION; PHENOTYPE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

ARABIDOPSIS;

EID: 47749129643     PISSN: 09607412     EISSN: 1365313X     Source Type: Journal    
DOI: 10.1111/j.1365-313X.2008.03521.x     Document Type: Article

References (27)

1. Abeles, F.B., Morgan, P.W. Saltveit, M.E. Jr (1992) Ethylene in Plant Biology, 2nd edn. New York : Academic Press.
2. Alonso, J.M., Hirayama, T., Roman, G., Nourizadeh, S. Ecker, J.R. (1999) EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis. Science, 284, 2148 2152.
3. Alonso, J.M., Stepanova, A.N., Solano, R., Wisman, E., Ferrari, S., Ausubel, F.M. Ecker, J.R. (2003) Five components of the ethylene-response pathway identified in a screen for weak ethylene insensitive mutants in Arabidopsis. Proc. Natl Acad. Sci. USA, 100, 2992 2997.
4. Benavente, L.M. Alonso, J.M. (2006) Molecular mechanisms of ethylene signaling in Arabidopsis. Mol. Biosyst. 2, 165 173.
5. Binder, B.M., Mortimore, L.A., Stepanova, A.N., Ecker, J.R. Bleecker, A.B. (2004) Short-term growth responses to ethylene in Arabidopsis seedlings are EIN3/EIL1 independent. Plant Physiol. 136, 2921 2927.
6. Binder, B.M., Walker, J.M., Gagne, J.M., Emborg, T.J., Hemmann, G., Bleecker, A.B. Vierstra, R.D. (2007) The Arabidopsis EIN3 binding F-box proteins EBF1 and EBF2 have distinct but overlapping roles in ethylene signaling. Plant Cell, 19, 509 523.
7. Buttner, M. Singh, K. (1997) Arabidopsis thaliana ethylene-responsive element binding protein (AtEBP), an ethylene-inducible, GCC box DNA-binding protein interacts with an ocs element binding protein. Proc. Natl Acad. Sci. USA, 94, 5961 5966.
8. Cancel, J.D. Larsen, P.B. (2002) Loss-of-function mutations in the ethylene receptor ETR1 cause enhanced sensitivity and exaggerated response to ethylene in Arabidopsis. Plant Physiol. 129, 1557 1567.
9. Chao, Q., Rothenberg, M., Solano, R., Roman, G., Terzaghi, W. Ecker, J.R. (1997) Activation of the ethylene gas response pathway in Arabidopsis by the nuclear protein ETHYLENE INSENSITIVE3 and related proteins. Cell, 89, 1133 1144.
10. Christians, M.J. Larsen, P.B. (2007) Mutational loss of the prohibitin AtPHB3 results in an extreme constitutive ethylene response phenotype coupled with partial loss of ethylene-inducible gene expression in Arabidopsis seedlings. J. Exp. Bot. 58, 2237 2248.
11. Gagne, J.M., Smalle, J., Gingerich, D.J., Walker, J.M., Yoo, S.-D., Yanagisawa, S. Vierstra, R.D. (2004) Arabidopsis EIN3-binding F-box 1 and 2 form ubiquitin-protein ligases that repress ethylene action and promote growth by directing EIN3 degradation. Proc. Natl Acad. Sci. USA, 101, 6803 6808.
12. EBF1/EBF2 dependent proteolysis of EIN3 transcription factor. Cell, 115, 667 677.
13. Gusmaroli, G., Figueroa, P., Serino, G. Deng, X.W. (2007) Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases. Plant Cell, 19, 564 581.
14. Hua, J. Meyerowitz, E.M. (1998) Ethylene responses are negatively regulated by a receptor gene family in Arabidopsis thaliana. Cell, 94, 261 271.
15. Kieber, J.J., Rothenberg, M., Roman, G., Feldmann, K.A. Ecker, J.R. (1993) CTR1, a negative regulator of the ethylene response pathway in Arabidopsis, encodes a member of the Raf family of protein kinases. Cell, 72, 427 441.
16. Larsen, P.B. Cancel, J.D. (2003) Enhanced ethylene responsiveness in the Arabidopsis eer1 mutant results from a loss-of-function mutation in the protein phosphatase 2A A regulatory subunit, RCN1. Plant J. 34, 709 718.
17. Larsen, P.B. Chang, C. (2001) The Arabidopsis eer1 mutant has enhanced ethylene responses in the hypocotyl and stem. Plant Physiol. 125, 1061 1073.
18. Maytal-Kivity, V., Piran, R., Pick, E., Hofmann, K. Glickman, M.H. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep. 3, 1215 1221.
19. Maytal-Kivity, V., Pick, E., Piran, R., Hofmann, K. Glickman, M.H. (2003) The COP9 signalosome-like complex in S. cerevisiae and links to other PCI complexes. Int. J. Biochem. Cell Biol. 35, 706 715.
20. Peng, Z., Serino, G. Deng, X.W. (2001a) Molecular characterization of subunit 6 of the COP9 signalosome and its role in multifaceted developmental processes in Arabidopsis. Plant Cell, 13, 2393 2407.
21. Peng, Z., Serino, G. Deng, X.W. (2001b) A role of Arabidopsis COP9 signalosome in multifaceted developmental processes revealed by the characterization of its subunit 3. Development, 128, 4277 4288.
22. Pfaffl, M.W. (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res, 29, e45.
23. Potuschak, T., Lechner, E., Parmentier, Y., Yanagisawa, S., Grava, S., Koncz, C. Genschik, P. (2003) EIN3-dependent regulation of plant ethylene hormone signaling by two Arabidopsis F box proteins EBF1 and EBF2. Cell, 115, 679 689.
24. Robles, L.M., Wampole, J.S., Christians, M.J. Larsen, P.B. (2007) Arabidopsis enhanced ethylene response 4 encodes an EIN3-interacting TFIID transcription factor required for proper ethylene response, including ERF1 induction. J. Exp. Bot. 58, 2627 2639.
25. Solano, R., Stepanova, A., Chao, Q. Ecker, J.R. (1998) Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE RESPONSE-FACTOR1. Genes Dev. 12, 3703 3714.
26. Wei, N. Deng, X.W. (2003) The COP9 signalosome. Annu. Rev. Cell Dev. Biol. 19, 261 286.
27. Wei, N., Kowk, S.F., von Arnim, A.G., Lee, A., McNellis, T.W., Piekos, B. Deng, X.W. (1994) Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development. Cell, 78, 117 124.