메뉴 건너뛰기




Volumn 53, Issue 2, 2008, Pages 139-146

Activated Stat3 expression in gestational trophoblastic disease: Correlation with clinicopathological parameters and apoptotic indices

Author keywords

Gestational trophoblastic disease; Stat3

Indexed keywords

DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DNA NUCLEOTIDYLEXOTRANSFERASE; STAT3 PROTEIN;

EID: 47749120647     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2008.03089.x     Document Type: Article
Times cited : (26)

References (43)
  • 2
    • 0141694787 scopus 로고    scopus 로고
    • Gestational trophoblastic diseases and related lesions
    • In. Kurman, R.J. ed. New York: Springer-Verlag
    • Shih IM, Mazur MT, Kurman RJ. Gestational trophoblastic diseases and related lesions. In Kurman RJ ed. Blaustein's pathology of the female genital trac. New York: Springer-Verlag, 2002 1193 1224.
    • (2002) Blaustein's Pathology of the Female Genital Trac. , pp. 1193-1224
    • Shih, I.M.1    Mazur, M.T.2    Kurman, R.J.3
  • 5
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE Jr., Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994 264 1415 1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 6
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler C, Darnell JE Jr. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem. 1995 64 621 651.
    • (1995) Annu. Rev. Biochem. , vol.64 , pp. 621-651
    • Schindler, C.1    Darnell Jr., J.E.2
  • 7
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell JE Jr. STATs and gene regulation. Science 1997 277 1630 1635.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell Jr., J.E.1
  • 8
    • 0034657336 scopus 로고    scopus 로고
    • The role of STATs in transcriptional control and their impact on cellular function
    • Bromberg J, Darnell JE Jr. The role of STATs in transcriptional control and their impact on cellular function. Oncogene 2000 19 2468 2473.
    • (2000) Oncogene , vol.19 , pp. 2468-2473
    • Bromberg, J.1    Darnell Jr., J.E.2
  • 9
    • 0032127977 scopus 로고    scopus 로고
    • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
    • Niwa H, Burdon T, Chambers I, Smith A. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev. 1998 12 2048 2060.
    • (1998) Genes Dev. , vol.12 , pp. 2048-2060
    • Niwa, H.1    Burdon, T.2    Chambers, I.3    Smith, A.4
  • 10
    • 33947574564 scopus 로고    scopus 로고
    • Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: Modern target but ancient solution
    • Aggarwal BB, Sethi G, Ahn KS et al. Targeting signal-transducer-and- activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution. Ann. NY Acad. Sci. 2006 1091 151 169.
    • (2006) Ann. NY Acad. Sci. , vol.1091 , pp. 151-169
    • Aggarwal, B.B.1    Sethi, G.2    Ahn, K.S.3
  • 11
    • 34250217027 scopus 로고    scopus 로고
    • Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6
    • Azare J, Leslie K, Al-Ahmadie H et al. Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6. Mol. Cell. Biol. 2007 27 4444 4453.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 4444-4453
    • Azare, J.1    Leslie, K.2    Al-Ahmadie, H.3
  • 13
    • 0242285719 scopus 로고    scopus 로고
    • STAT proteins: From normal control of cellular events to tumorigenesis
    • Calo V, Migliavacca M, Bazan V et al. STAT proteins: from normal control of cellular events to tumorigenesis. J. Cell. Physiol. 2003 197 157 168.
    • (2003) J. Cell. Physiol. , vol.197 , pp. 157-168
    • Calo, V.1    Migliavacca, M.2    Bazan, V.3
  • 14
    • 0032877019 scopus 로고    scopus 로고
    • The role of STATs in proliferation, differentiation, and apoptosis
    • Mui AL. The role of STATs in proliferation, differentiation, and apoptosis. Cell. Mol. Life Sci. 1999 55 1547 1558.
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 1547-1558
    • Mui, A.L.1
  • 15
    • 0034219458 scopus 로고    scopus 로고
    • Elevated phosphorylation of AKT and Stat3 in prostate, breast, and cervical cancer cells
    • Page C, Huang M, Jin X et al. Elevated phosphorylation of AKT and Stat3 in prostate, breast, and cervical cancer cells. Int. J. Oncol. 2000 17 23 28.
    • (2000) Int. J. Oncol. , vol.17 , pp. 23-28
    • Page, C.1    Huang, M.2    Jin, X.3
  • 16
    • 35348893870 scopus 로고    scopus 로고
    • Targeting the cytoplasmic and nuclear functions of signal transducers and activators of transcription 3 for cancer therapy
    • Germain D, Frank DA. Targeting the cytoplasmic and nuclear functions of signal transducers and activators of transcription 3 for cancer therapy. Clin. Cancer Res. 2007 13 5665 5669.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 5665-5669
    • Germain, D.1    Frank, D.A.2
  • 17
    • 17044432247 scopus 로고    scopus 로고
    • Trophoblast invasion: Tuning through LIF, signalling via Stat3
    • Poehlmann TG, Fitzgerald JS, Meissner A et al. Trophoblast invasion: tuning through LIF, signalling via Stat3. Placenta 2005 26 (Suppl. A S37 S41.
    • (2005) Placenta , vol.26
    • Poehlmann, T.G.1    Fitzgerald, J.S.2    Meissner, A.3
  • 18
    • 23944433875 scopus 로고    scopus 로고
    • Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells
    • Fitzgerald JS, Tsareva SA, Poehlmann TG et al. Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells. Int. J. Biochem. Cell Biol. 2005 37 2284 2296.
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 2284-2296
    • Fitzgerald, J.S.1    Tsareva, S.A.2    Poehlmann, T.G.3
  • 20
    • 0030744123 scopus 로고    scopus 로고
    • Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3
    • Wen Z, Darnell JE Jr. Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3. Nucleic Acids Res. 1997 25 2062 2067.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2062-2067
    • Wen, Z.1    Darnell Jr., J.E.2
  • 21
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen Z, Zhong Z, Darnell JE Jr. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 1995 82 241 250.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 22
    • 1642348690 scopus 로고    scopus 로고
    • Metastatic trophoblastic disease after an initial diagnosis of partial hydatidiform mole: Genotyping and chromosome in situ hybridization analysis
    • Cheung AN, Khoo US, Lai CY et al. Metastatic trophoblastic disease after an initial diagnosis of partial hydatidiform mole: genotyping and chromosome in situ hybridization analysis. Cancer 2004 100 1411 1417.
    • (2004) Cancer , vol.100 , pp. 1411-1417
    • Cheung, A.N.1    Khoo, U.S.2    Lai, C.Y.3
  • 23
    • 1642301713 scopus 로고    scopus 로고
    • Analysis of gestational trophoblastic disease by genotyping and chromosome in situ hybridization
    • Lai CY, Chan KY, Khoo US et al. Analysis of gestational trophoblastic disease by genotyping and chromosome in situ hybridization. Mod. Pathol. 2004 17 40 48.
    • (2004) Mod. Pathol. , vol.17 , pp. 40-48
    • Lai, C.Y.1    Chan, K.Y.2    Khoo, U.S.3
  • 24
    • 0034818856 scopus 로고    scopus 로고
    • Apoptotic activity in gestational trophoblastic disease correlates with clinical outcome: Assessment by the caspase-related M30 CytoDeath antibody
    • Chiu PM, Ngan YS, Khoo US, Cheung AN. Apoptotic activity in gestational trophoblastic disease correlates with clinical outcome: assessment by the caspase-related M30 CytoDeath antibody. Histopathology 2001 38 243 249.
    • (2001) Histopathology , vol.38 , pp. 243-249
    • Chiu, P.M.1    Ngan, Y.S.2    Khoo, U.S.3    Cheung, A.N.4
  • 25
    • 0032708058 scopus 로고    scopus 로고
    • Apoptosis in gestational trophoblastic disease is correlated with clinical outcome and Bcl-2 expression but not Bax expression
    • Wong SY, Ngan HY, Chan CC, Cheung AN. Apoptosis in gestational trophoblastic disease is correlated with clinical outcome and Bcl-2 expression but not Bax expression. Mod. Pathol. 1999 12 1025 1033.
    • (1999) Mod. Pathol. , vol.12 , pp. 1025-1033
    • Wong, S.Y.1    Ngan, H.Y.2    Chan, C.C.3    Cheung, A.N.4
  • 26
    • 24144431605 scopus 로고    scopus 로고
    • Id helix-loop-helix proteins are differentially expressed in gestational trophoblastic disease
    • Xue WC, Feng HC, Chan KY et al. Id helix-loop-helix proteins are differentially expressed in gestational trophoblastic disease. Histopathology 2005 47 303 309.
    • (2005) Histopathology , vol.47 , pp. 303-309
    • Xue, W.C.1    Feng, H.C.2    Chan, K.Y.3
  • 27
    • 0344844595 scopus 로고    scopus 로고
    • Minichromosome maintenance protein 7 expression in gestational trophoblastic disease: Correlation with Ki67, PCNA and clinicopathological parameters
    • Xue WC, Khoo US, Ngan HY et al. Minichromosome maintenance protein 7 expression in gestational trophoblastic disease: correlation with Ki67, PCNA and clinicopathological parameters. Histopathology 2003 43 485 490.
    • (2003) Histopathology , vol.43 , pp. 485-490
    • Xue, W.C.1    Khoo, U.S.2    Ngan, H.Y.3
  • 28
    • 18144428330 scopus 로고    scopus 로고
    • Establishment and characterization of a human first-trimester extravillous trophoblast cell line (TEV-1)
    • Feng HC, Choy MY, Deng W et al. Establishment and characterization of a human first-trimester extravillous trophoblast cell line (TEV-1). J. Soc. Gynecol. Investig. 2005 12 e21 e32.
    • (2005) J. Soc. Gynecol. Investig. , vol.12
    • Feng, H.C.1    Choy, M.Y.2    Deng, W.3
  • 29
    • 1242277423 scopus 로고    scopus 로고
    • Methylation status and expression of E-cadherin and cadherin-11 in gestational trophoblastic diseases
    • Xue WC, Feng HC, Tsao SW et al. Methylation status and expression of E-cadherin and cadherin-11 in gestational trophoblastic diseases. Int. J. Gynecol. Cancer. 2003 13 879 888.
    • (2003) Int. J. Gynecol. Cancer. , vol.13 , pp. 879-888
    • Xue, W.C.1    Feng, H.C.2    Tsao, S.W.3
  • 30
    • 33751575658 scopus 로고    scopus 로고
    • The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis
    • Rosen DG, Mercado-Uribe I, Yang G et al. The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis. Cancer 2006 107 2730 2740.
    • (2006) Cancer , vol.107 , pp. 2730-2740
    • Rosen, D.G.1    Mercado-Uribe, I.2    Yang, G.3
  • 31
    • 33749365493 scopus 로고    scopus 로고
    • Adding fuel to the fire: STAT3 priming of gastric tumorigenesis
    • Denson LA. Adding fuel to the fire: STAT3 priming of gastric tumorigenesis. Gastroenterology 2006 131 1342 1344.
    • (2006) Gastroenterology , vol.131 , pp. 1342-1344
    • Denson, L.A.1
  • 32
    • 33749328700 scopus 로고    scopus 로고
    • STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis
    • Judd LM, Bredin K, Kalantzis A, Jenkins BJ, Ernst M, Giraud AS. STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis. Gastroenterology 2006 131 1073 1085.
    • (2006) Gastroenterology , vol.131 , pp. 1073-1085
    • Judd, L.M.1    Bredin, K.2    Kalantzis, A.3    Jenkins, B.J.4    Ernst, M.5    Giraud, A.S.6
  • 33
    • 33644796472 scopus 로고    scopus 로고
    • Stat3 activation is required for cell proliferation and tumorigenesis but not for cell viability in cutaneous squamous cell carcinoma cell lines
    • Sumita N, Bito T, Nakajima K, Nishigori C. Stat3 activation is required for cell proliferation and tumorigenesis but not for cell viability in cutaneous squamous cell carcinoma cell lines. Exp. Dermatol. 2006 15 291 299.
    • (2006) Exp. Dermatol. , vol.15 , pp. 291-299
    • Sumita, N.1    Bito, T.2    Nakajima, K.3    Nishigori, C.4
  • 34
    • 0032542211 scopus 로고    scopus 로고
    • Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)
    • Jain N, Zhang T, Fong SL, Lim CP, Cao X. Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK). Oncogene 1998 17 3157 3167.
    • (1998) Oncogene , vol.17 , pp. 3157-3167
    • Jain, N.1    Zhang, T.2    Fong, S.L.3    Lim, C.P.4    Cao, X.5
  • 35
    • 0030772458 scopus 로고    scopus 로고
    • STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation
    • Chung J, Uchida E, Grammer TC, Blenis J. STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation. Mol. Cell. Biol. 1997 17 6508 6516.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6508-6516
    • Chung, J.1    Uchida, E.2    Grammer, T.C.3    Blenis, J.4
  • 36
    • 0035877595 scopus 로고    scopus 로고
    • Regulation of Stat3 activation by MEK kinase 1
    • Lim CP, Cao X. Regulation of Stat3 activation by MEK kinase 1. J. Biol. Chem. 2001 276 21004 21011.
    • (2001) J. Biol. Chem. , vol.276 , pp. 21004-21011
    • Lim, C.P.1    Cao, X.2
  • 37
    • 0032530159 scopus 로고    scopus 로고
    • Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases
    • Sengupta TK, Talbot ES, Scherle PA, Ivashkiv LB. Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases. Proc. Natl. Acad. Sci. USA 1998 95 11107 11112.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 11107-11112
    • Sengupta, T.K.1    Talbot, E.S.2    Scherle, P.A.3    Ivashkiv, L.B.4
  • 38
    • 12344276322 scopus 로고    scopus 로고
    • Mcl-1 expression in gestational trophoblastic disease correlates with clinical outcome: A differential expression study
    • Fong PY, Xue WC, Ngan HY et al. Mcl-1 expression in gestational trophoblastic disease correlates with clinical outcome: a differential expression study. Cancer 2005 103 268 276.
    • (2005) Cancer , vol.103 , pp. 268-276
    • Fong, P.Y.1    Xue, W.C.2    Ngan, H.Y.3
  • 39
    • 8744242129 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in hydatidiform mole and choriocarcinoma
    • Xue WC, Chan KY, Feng HC et al. Promoter hypermethylation of multiple genes in hydatidiform mole and choriocarcinoma. J. Mol. Diagn. 2004 6 326 334.
    • (2004) J. Mol. Diagn. , vol.6 , pp. 326-334
    • Xue, W.C.1    Chan, K.Y.2    Feng, H.C.3
  • 40
    • 0036625960 scopus 로고    scopus 로고
    • The role of STATs in apoptosis
    • Battle TE, Frank DA. The role of STATs in apoptosis. Curr. Mol. Med. 2002 2 381 392.
    • (2002) Curr. Mol. Med. , vol.2 , pp. 381-392
    • Battle, T.E.1    Frank, D.A.2
  • 41
    • 0034658541 scopus 로고    scopus 로고
    • Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
    • Hirano T, Ishihara K, Hibi M. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 2000 19 2548 2556.
    • (2000) Oncogene , vol.19 , pp. 2548-2556
    • Hirano, T.1    Ishihara, K.2    Hibi, M.3
  • 42
    • 0036731485 scopus 로고    scopus 로고
    • Stats: Transcriptional control and biological impact
    • Levy DE, Darnell JE Jr. Stats: transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 2002 3 651 662.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell Jr., J.E.2
  • 43
    • 28744459372 scopus 로고    scopus 로고
    • Physical and functional interactions between STAT3 and ZIP kinase
    • Sato N, Kawai T, Sugiyama K et al. Physical and functional interactions between STAT3 and ZIP kinase. Int. Immunol. 2005 17 1543 1552.
    • (2005) Int. Immunol. , vol.17 , pp. 1543-1552
    • Sato, N.1    Kawai, T.2    Sugiyama, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.