Formation of the N-methylpyridinium derivative to improve the detection of buprenorphine by liquid chromatography-mass spectrometry

Journal of Mass Spectrometry

Volumn 43, Issue 7, 2008, Pages 974-979

  Thieme, Detlef ^a,b   Sachs, Hans ^b   Thevis, Mario ^c  

^a UNIVERSITY OF MUNICH   (Germany)

^b Forensic Toxicological Centre   (Germany)

^c GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

Author keywords

Buprenorphine; Derivatisation; Doping analysis; Forensic toxicology; Hair analysis; LC MS

Indexed keywords

ACETONITRILE; BODY FLUIDS; CHEMICAL MODIFICATION; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROLYSIS; ELECTROSPRAY IONIZATION; ETHERS; HEALTH; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION CHROMATOGRAPHY; IONIZATION OF LIQUIDS; IONS; MASS SPECTROMETERS; MASS SPECTROMETRY; ORGANIC COMPOUNDS; ORGANIC POLYMERS; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; TOLUENE;

AMBIENT TEMPERATURES; BIOLOGICAL SPECIMENS; BUPRENORPHINE (BUP); DETECTION LIMIT (DL); ELECTROSPRAY (ES); HIGH SPECIFICITY; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY (LC/MS); N METHYLPYRIDINIUM; PRODUCT IONS; PYRIDINIUM; SELECTIVITY AND SENSITIVITY; TRIETHYLAMINE (TEA);

LIQUID CHROMATOGRAPHY;

2 FLUORO 1 METHYLPYRIDINIUM 4 TOLYLSULFONATE; ACETONITRILE; BUPRENORPHINE; NORBUPRENORPHINE; PYRIDINIUM DERIVATIVE; TRIETHYLAMINE;

ARTICLE; CATALYST; CHEMICAL MODIFICATION; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; HAIR ANALYSIS; HUMAN; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

BUPRENORPHINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HAIR; HUMANS; NARCOTICS; PYRIDINIUM COMPOUNDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBSTANCE ABUSE DETECTION; TANDEM MASS SPECTROMETRY;

EID: 47749106833     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1433     Document Type: Article

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