Buprenorphine and norbuprenorphine in hair of pregnant women and their infants after controlled buprenorphine administration

Clinical Chemistry

Volumn 53, Issue 12, 2007, Pages 2136-2143

  Goodwin, Robert S ^a   Wilkins, Diana G ^b   Averin, Olga ^b   Choo, Robin E ^a,c   Schroeder, Jennifer R ^a   Jasinski, Donald R ^d   Johnson, Rolley E ^e   Jones, Hendrée E ^d   Huestis, Marilyn A ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e RECKITT BENCKISER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUPRENORPHINE; DICHLOROMETHANE; METHADONE; NORBUPRENORPHINE; OPIATE AGONIST; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG DISPOSITION; DRUG MONITORING; FEMALE; HAIR ANALYSIS; HAIR FOLLICLE; HEROIN DEPENDENCE; HUMAN; INFANT; LIQUID CHROMATOGRAPHY; PREGNANCY; PREGNANT WOMAN; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TANDEM MASS SPECTROMETRY;

ADULT; BUPRENORPHINE; CHROMATOGRAPHY, LIQUID; FEMALE; HAIR; HEROIN DEPENDENCE; HUMANS; INFANT; INFANT, NEWBORN; PREGNANCY; PREGNANCY COMPLICATIONS; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION;

EID: 36649023083     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2007.091413     Document Type: Article

References (16)

1. Nocon JJ. Buprenorphine in pregnancy: the advantages. Addiction 2006;101:608.
2. Jones HE, Johnson RE, Jasinski DR, O'Grady KE, Chisholm CA, Choo RE, et al. Buprenorphine versus methadone in the treatment of pregnant opioid-dependent patients: effects on the neonatal abstinence syndrome. Drug Alcohol Depend 2005;79:1-10.
3. Lejeune C, Simmat-Durand L, Gourarier L, Aubisson S. Prospective multicenter observational study of 260 infants born to 259 opiate-dependent mothers on methadone or high-dose buprenophine substitution. Drug Alcohol Depend 2006;82:250-7.
4. Scheidweiler KB, Cone EJ, Moolchan ET, Huestis MA. Dose-related distribution of codeine, cocaine, and metabolites into human hair following controlled oral codeine and subcutaneous cocaine administration. J Pharmacol Exp Ther 2005;313:909-15.
5. Vinner E, Vignau J, Thibault D, Codaccioni X, Brassart C, Humbert L, et al. Hair analysis of opiates in mothers and newborns for evaluating opiate exposure during pregnancy. Forensic Sci Int 2003;133:57-62.
6. Bar-Oz B, Klein J, Karaskov T, Koren G. Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse. Arch Dis Child Fetal Neonatal Ed 2003;88:F98-100.
7. Cirimele V, Kintz P, Mangin P. Testing human hair for cannabis. Forensic Sci Int 1995;70:175-82.
8. Cone EJ, Gorodetzky CW, Yousefnejad D, Buchwald WF, Johnson RE. The metabolism and excretion of buprenorphine in humans. Drug Metab Dispos 1984;12:577-81.
9. Thompson. Suboxone. 2005 Physicians Desk Reference. 2005:2830.
10. Kuhlman JJ, Lalani S, Magluilo J, Levine B, Darwin WD, Johnson RE, et al. Human pharmacokinetics of intravenous, sublingual, and buccal buprenorphine. J Anal Toxicol 1996;20:369-78.
11. Kintz P. Determination of buprenorphine and its dealkylated metabolite in human hair. J Anal Toxicol 1993;17:443-4.
12. Kintz P, Cirimele V, Edel Y, Jamey C, Mangin P. Hair analysis for buprenorphine and its dealkylated metabolite by RIA and confirmation by LC/ECD. J Forensic Sci 1994;39:1497-503.
13. Tracqui A, Kintz P, Mangin P. HPLC-MS determination of buprenorphine and norbuprenorphine in biological fluids and hair samples. J Forensic Sci 1997;42:111-4.
14. Wilkins DG, Rollins DE, Valdez AS, Mizuno A, Krueger GC, Cone EJ. A retrospective study of buprenorphine and norbuprenorphine in human hair after multiple doses. J Anal Toxicol 1999;23:409-15.
15. Vincent F, Bessard J, Vacheron J, Mallaret M, Bessard G. Determination of buprenorphine and norbuprenorphine in urine and hair by gas chromatography-mass spectrometry. J Anal Toxicol 1999;23:270-9.
16. Cirimele V, Kintz P, Lohner S, Ludes B. Buprenorphine to norbuprenorphine ratio in human hair. J Anal Toxicol 2000;24:448-9.