Decorin derived antiangiogenic peptide LRR5 inhibits endothelial cell migration by interfering with VEGF-stimulated NO release

International Journal of Biochemistry and Cell Biology

Volumn 40, Issue 10, 2008, Pages 2120-2128

  Fan, Huapeng ^a   Sulochana, K N ^a   Chong, Yap Seng ^a   Ge, Ruowen ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Decorin; Endothelial cell migration; NO; PI3K Akt eNOS signaling; VEGF

Indexed keywords

ANGIOGENESIS INHIBITOR; DECORIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTAMINYLMETHIONYLISOLEUCYLVALYLISOLEUCYLGLUTAMYLLEUCYL GLYCYLTHREONYLASPARAGINYLPROLYLLEUCYLLYSINE; GLUTAMINYLMETHIONYLISOLEUCYLVALYLISOLEUCYLGLUTAMYLLEUCYLGLYCYL THREONYLASPARAGINYLPROLYLLEUCYLLYSYLSERYLSERYLGLYCYLISOLEUCYLGLUTAMYL GLYCYLALANYLPHENYLALANYLGLUTAMINYLGLYCYLMETHIONYLLYSINE; LEUCINE RICH REPEAT 5; LEUCINE RICH REPEAT 5C; LEUCINE RICH REPEAT 5M; LEUCINE RICH REPEAT 5N; LEUCYLGLYCYLTHREONYLASPARAGINYLPROLYLLEUCYLLYSYLSERYLSERYL GLYCYLISOLEUCYLGLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SERYLSERYLGLYCYLISOLEUCYLGLUTAMYLASPARAGINYLGLYCYLALANYL PHENYLALANYLGLUTAMINYLGLYCYLMETHIONYLLYSINE; VASCULOTROPIN;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MIGRATION; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MIGRATION INHIBITION; MOLECULAR MECHANICS; PROTEIN FUNCTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANGIOGENESIS INHIBITORS; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; EXTRACELLULAR MATRIX PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MODELS, BIOLOGICAL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PEPTIDES; PHOSPHORYLATION; PHOSPHOSERINE; PROTEINS; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS C-AKT; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 47649085593     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.02.009     Document Type: Article

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