-
1
-
-
35448998256
-
-
National Cancer Institute of Canada, Toronto, ON, Canada
-
National Cancer Institute of Canada. Canadian Cancer Statistics 2007. Toronto, ON, Canada (2007).
-
(2007)
Canadian Cancer Statistics 2007
-
-
-
2
-
-
33947593200
-
-
American Cancer Society, Atlant, GA, USA
-
American Cancer Society. Cancer facts and figures 2007. Atlant, GA, USA (2007).
-
(2007)
Cancer facts and figures 2007
-
-
-
3
-
-
0346238665
-
Cisplatinum-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer
-
The International Adjuvant Lung Cancer Trial Collaborative Group
-
The International Adjuvant Lung Cancer Trial Collaborative Group. Cisplatinum-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. N. Engl. J. Med. 350(4), 351-360 (2004).
-
(2004)
N. Engl. J. Med
, vol.350
, Issue.4
, pp. 351-360
-
-
-
4
-
-
20544455590
-
Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer
-
Winton T, Livingston R, Johnson D et al. Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer. N. Engl. J. Med. 352(25), 2589-2597 (2005).
-
(2005)
N. Engl. J. Med
, vol.352
, Issue.25
, pp. 2589-2597
-
-
Winton, T.1
Livingston, R.2
Johnson, D.3
-
5
-
-
0028216204
-
A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer
-
Roth J, Fossella F, Komaki R et al. A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer. J. Natl. Cancer Inst. 86(9), 673-680 (1994).
-
(1994)
J. Natl. Cancer Inst
, vol.86
, Issue.9
, pp. 673-680
-
-
Roth, J.1
Fossella, F.2
Komaki, R.3
-
6
-
-
0027957929
-
A randomized trial comparing preoperative chemotherapy plus surgery with surgery alone in patients with non-small-cell lung cancer
-
Rosell R, Gomez-Codina J, Camps C et al. A randomized trial comparing preoperative chemotherapy plus surgery with surgery alone in patients with non-small-cell lung cancer. N. Engl. J. Med. 330(3), 153-158 (1994).
-
(1994)
N. Engl. J. Med
, vol.330
, Issue.3
, pp. 153-158
-
-
Rosell, R.1
Gomez-Codina, J.2
Camps, C.3
-
7
-
-
0036139728
-
-
Depierre A, Milleron B, Moro-Sibilot D et al. Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (Except TIM), II, IIIa non-small-cell lung cancer. J. Clin. Oncol. 20(1), 247-253 (2002).
-
Depierre A, Milleron B, Moro-Sibilot D et al. Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (Except TIM), II, IIIa non-small-cell lung cancer. J. Clin. Oncol. 20(1), 247-253 (2002).
-
-
-
-
8
-
-
24944542868
-
Combined chemoradiotherapy regimens of paclitaxel and carboplatin for locally advanced non-small-cell lung cancer: A randomized phase II locally advanced multi-modality protocol
-
Belani CP, Choy H, Bonomi P et al. Combined chemoradiotherapy regimens of paclitaxel and carboplatin for locally advanced non-small-cell lung cancer: a randomized phase II locally advanced multi-modality protocol. J. Clin. Oncol. 23(25), 5883-5891 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.25
, pp. 5883-5891
-
-
Belani, C.P.1
Choy, H.2
Bonomi, P.3
-
9
-
-
0025009172
-
A randomized trial of induction chemotherapy plus high-dose radiation versus radiation alone in Stage III Non-small-cell lung cancer
-
DiUman R, Seagrean S, Propert K et al. A randomized trial of induction chemotherapy plus high-dose radiation versus radiation alone in Stage III Non-small-cell lung cancer. N. Engl. J Med. 323(14), 940-945 (1990).
-
(1990)
N. Engl. J Med
, vol.323
, Issue.14
, pp. 940-945
-
-
DiUman, R.1
Seagrean, S.2
Propert, K.3
-
10
-
-
0033993435
-
Final results of phase III trial in regionally advanced unresectable non-small-cell lung cancer
-
Sause W, Kolesar P. Taylor S et al. Final results of phase III trial in regionally advanced unresectable non-small-cell lung cancer. Chest 117(2), 358-365 (2000).
-
(2000)
Chest
, vol.117
, Issue.2
, pp. 358-365
-
-
Sause, W.1
Kolesar, P.2
Taylor, S.3
-
11
-
-
0032858243
-
Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer
-
Furuse K, Fukuoka M, Kawahara M et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer. J. Clin. Oncol. 17(9), 2692-2699 (1999).
-
(1999)
J. Clin. Oncol
, vol.17
, Issue.9
, pp. 2692-2699
-
-
Furuse, K.1
Fukuoka, M.2
Kawahara, M.3
-
12
-
-
47649128241
-
-
Okawara G, Mackay JA, Evans WK, Ung YC and the Lung Cancer Disease Site Group. Management of unresected stage III non-small-cell lung cancer: a clinical practice guideline. Evidence-based series #7-3 (Version 2.2005): Section 1. A. Program of Cancer Care Ontario. Current report date: January 2006.
-
Okawara G, Mackay JA, Evans WK, Ung YC and the Lung Cancer Disease Site Group. Management of unresected stage III non-small-cell lung cancer: a clinical practice guideline. Evidence-based series #7-3 (Version 2.2005): Section 1. A. Program of Cancer Care Ontario. Current report date: January 2006.
-
-
-
-
13
-
-
0022628932
-
A new international staging system for lung cancer
-
Mountain CF. A new international staging system for lung cancer. Chest 89(4 Suppl.), S225-S233 (1986).
-
(1986)
Chest
, vol.89
, Issue.4 SUPPL.
-
-
Mountain, C.F.1
-
14
-
-
0028843552
-
Chemotherapy in non-small-cell lung cancer: A meta-analysis using updated date on individual patients from 52 randomized clinical trials
-
Non-small-cell lung cancer Collaborative Group
-
Non-small-cell lung cancer Collaborative Group. Chemotherapy in non-small-cell lung cancer: a meta-analysis using updated date on individual patients from 52 randomized clinical trials. BMJ 311(7010), 899-909 (1995).
-
(1995)
BMJ
, vol.311
, Issue.7010
, pp. 899-909
-
-
-
15
-
-
34548144758
-
Chemotherapy for non-small-cell lung cancer
-
Cochrane Lung Cancer Group, 4, 2004, Date of most recent substantive update: February 1
-
Cochrane Lung Cancer Group. Chemotherapy for non-small-cell lung cancer. Cochrane Database Syst. Rev. 4, (2004). Date of most recent substantive update: February 1, 2000.
-
(2000)
Cochrane Database Syst. Rev
-
-
-
16
-
-
2942657615
-
Randomized Phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
Johnson D, Fehrenbacher L, Novotny W et al. Randomized Phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J. Clin. Oncol. 22(11), 2184-2191 (2004).
-
(2004)
J. Clin. Oncol
, vol.22
, Issue.11
, pp. 2184-2191
-
-
Johnson, D.1
Fehrenbacher, L.2
Novotny, W.3
-
17
-
-
36048982143
-
Phase II Study of efficacy and safety of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non-small-cell lung cancer
-
Herbst R, O'Neill V, Fehrenbacher L et al. Phase II Study of efficacy and safety of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non-small-cell lung cancer.J. Clin. Oncol. 25(30), 1-8 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.30
, pp. 1-8
-
-
Herbst, R.1
O'Neill, V.2
Fehrenbacher, L.3
-
18
-
-
0034789572
-
Phase I study of the BLP25 (MUC1 peptide) liposomal vaccine for active specific immunotherapy in stage IIIB/IV non-small-cell lung cancer
-
Palmer M, Parker J, Modi S et al. Phase I study of the BLP25 (MUC1 peptide) liposomal vaccine for active specific immunotherapy in stage IIIB/IV non-small-cell lung cancer. Clin. Lung Cancer 3(1), 49-57 (2001)
-
(2001)
Clin. Lung Cancer
, vol.3
, Issue.1
, pp. 49-57
-
-
Palmer, M.1
Parker, J.2
Modi, S.3
-
19
-
-
0038350394
-
Lung cancer vaccines and gene therapy
-
Hege K, Carbone D. Lung cancer vaccines and gene therapy. Lung Cancer 41, S103-S113 (2003).
-
(2003)
Lung Cancer
, vol.41
-
-
Hege, K.1
Carbone, D.2
-
20
-
-
5144233489
-
Gene-based vaccines and immunotherapeutics
-
Liu M, Acres B, Balloul JM et al. Gene-based vaccines and immunotherapeutics. Proc. Natl Acad. Sci. USA. 101(2), 14567-14571 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.2
, pp. 14567-14571
-
-
Liu, M.1
Acres, B.2
Balloul, J.M.3
-
21
-
-
33846165064
-
A review of vaccine clinical trials for non-small-cell lung cancer
-
Nemunaitis J, Nemunaitis J. A review of vaccine clinical trials for non-small-cell lung cancer. Expert Opin. Biol. Ther. 7(1), 89-102 (2007).
-
(2007)
Expert Opin. Biol. Ther
, vol.7
, Issue.1
, pp. 89-102
-
-
Nemunaitis, J.1
Nemunaitis, J.2
-
22
-
-
34247891727
-
Immune-modulating vaccines in non-small-cell lung-cancer
-
Nemunaitis J, Murray N. Immune-modulating vaccines in non-small-cell lung-cancer.J. Thorac. Oncol. 1(7), 756-761 (2006).
-
(2006)
J. Thorac. Oncol
, vol.1
, Issue.7
, pp. 756-761
-
-
Nemunaitis, J.1
Murray, N.2
-
23
-
-
0037441842
-
Vaccination with irradiated autologous tumour cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor Immunity in some patients with metastatic non-small-cell lung cancer
-
Salgia. R, Lynch T, Skarin A et al. Vaccination with irradiated autologous tumour cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor Immunity in some patients with metastatic non-small-cell lung cancer. J. Clin. Oncol. 21(4), 624-630 (2003).
-
(2003)
J. Clin. Oncol
, vol.21
, Issue.4
, pp. 624-630
-
-
Salgia, R.1
Lynch, T.2
Skarin, A.3
-
24
-
-
4143077460
-
Metastatic breast tumour regression following treatment by a gene-modified vaccinia virus expressing MUC1 and 1L2
-
Scholl S, Squiban P, Bizouarne N et al. Metastatic breast tumour regression following treatment by a gene-modified vaccinia virus expressing MUC1 and 1L2. J. Biomed. Biotechnol. 3, 194-201 (2003).
-
(2003)
J. Biomed. Biotechnol
, vol.3
, pp. 194-201
-
-
Scholl, S.1
Squiban, P.2
Bizouarne, N.3
-
25
-
-
34247471316
-
Development of an antigen-presenting cell-targeted DNA vaccine against melanoma by mannosylated liposomes
-
Lu Y, Kawakami S, Yamashita F, Hasida M. Development of an antigen-presenting cell-targeted DNA vaccine against melanoma by mannosylated liposomes. Biomaterials 28(21), 3255-3262 (2007).
-
(2007)
Biomaterials
, vol.28
, Issue.21
, pp. 3255-3262
-
-
Lu, Y.1
Kawakami, S.2
Yamashita, F.3
Hasida, M.4
-
26
-
-
0028235908
-
Humoral immunity against a tandem repeat epitope of human mucin MUC1 in sera from breast, pancreatic and colon cancer patients
-
Kotera Y, Fontenot J, Pecher G et al. Humoral immunity against a tandem repeat epitope of human mucin MUC1 in sera from breast, pancreatic and colon cancer patients. Cancer Res. 54, 2856-2860 (1994).
-
(1994)
Cancer Res
, vol.54
, pp. 2856-2860
-
-
Kotera, Y.1
Fontenot, J.2
Pecher, G.3
-
27
-
-
0025029968
-
Molecular cloning and expression of human tumour-associated polymorphic epithelial mucin
-
Gendler S, Lancaster C, Taylor-Papadimitriou J et al. Molecular cloning and expression of human tumour-associated polymorphic epithelial mucin. J. Biol. Chem. 265, 15286-15293 (1990).
-
(1990)
J. Biol. Chem
, vol.265
, pp. 15286-15293
-
-
Gendler, S.1
Lancaster, C.2
Taylor-Papadimitriou, J.3
-
28
-
-
0027234998
-
Immunogenicity of synthetic peptides related to the core peptide sequence encoded by the human MUC1 mucin gene: Effect of immunization on the growth of murine mammary adenocarcinoma cells transfected with the human MUC1 gene
-
Ding L, Lalani EN, Reddish M et al. Immunogenicity of synthetic peptides related to the core peptide sequence encoded by the human MUC1 mucin gene: effect of immunization on the growth of murine mammary adenocarcinoma cells transfected with the human MUC1 gene. Cancer Immunol. Immunother. 36, 9-17 (1993).
-
(1993)
Cancer Immunol. Immunother
, vol.36
, pp. 9-17
-
-
Ding, L.1
Lalani, E.N.2
Reddish, M.3
-
29
-
-
0027464958
-
Heterogeneity of mucin gene expression in normal and neoplastic tissue
-
Ho S, Niehans G, Lyftogt C et al. Heterogeneity of mucin gene expression in normal and neoplastic tissue. Cancer Res. 53, 641-651 (1993).
-
(1993)
Cancer Res
, vol.53
, pp. 641-651
-
-
Ho, S.1
Niehans, G.2
Lyftogt, C.3
-
30
-
-
10744220453
-
Human MUC1. carcinoma-associated protein confers resistance to genotoxic anticancer agents
-
Ren J, Agata N, Chen D et al Human MUC1. carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell. 5, 163-175 (2004).
-
(2004)
Cancer Cell
, vol.5
, pp. 163-175
-
-
Ren, J.1
Agata, N.2
Chen, D.3
-
31
-
-
0031914321
-
Cancer-associated MUC1 inhibits human T-cell proliferation, which is reversible by IL-2
-
Agrawal B, Krantz M, Reddish M, Longeneckder M. Cancer-associated MUC1 inhibits human T-cell proliferation, which is reversible by IL-2. Nat. Med. 4(1), 43-49 (1998).
-
(1998)
Nat. Med
, vol.4
, Issue.1
, pp. 43-49
-
-
Agrawal, B.1
Krantz, M.2
Reddish, M.3
Longeneckder, M.4
-
32
-
-
34547661985
-
L-BLP25: A peptide vaccine strategy in non-small-cell lung cancer
-
Sangha R, Butts C. L-BLP25: a peptide vaccine strategy in non-small-cell lung cancer. Clin. Cancer Res. 13(15 Suppl.), S4652-S4654 (2007).
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.15 SUPPL.
-
-
Sangha, R.1
Butts, C.2
-
33
-
-
4344713204
-
Phase I trial of antigen-specific gene therapy using a recombinant vaccinia virus encoding MUC-1 and 11-2 in MUC-1-positive patients with advanced prostate cancer
-
Pantuck A, van Ophoven A, Giditz; B et al. Phase I trial of antigen-specific gene therapy using a recombinant vaccinia virus encoding MUC-1 and 11-2 in MUC-1-positive patients with advanced prostate cancer.J Immunother. 27(3), 240-253 (2004).
-
(2004)
J Immunother
, vol.27
, Issue.3
, pp. 240-253
-
-
Pantuck, A.1
van Ophoven, A.2
Giditz, B.3
-
34
-
-
47649085684
-
-
Squiban P, Velu T, Mennecier B et al. NWA-MUCI-IL2 vaccine immunotherapy for advanced non-small-cell. lung cancer (NSCLC): interim Phase II data. J. Clin. Oncol. Annual meeting proceedings (Post-Meeting Edition) 22(Suppl. 145), 2544 (2004).
-
Squiban P, Velu T, Mennecier B et al. NWA-MUCI-IL2 vaccine immunotherapy for advanced non-small-cell. lung cancer (NSCLC): interim Phase II data. J. Clin. Oncol. Annual meeting proceedings (Post-Meeting Edition) 22(Suppl. 145), 2544 (2004).
-
-
-
-
35
-
-
0032127618
-
Liposomal formulations of synthetic MUC1 peptides: Effects of encapsulation versus surface display of peptides on immune responses
-
Guan H, Budzynski W, Koganty R et al. Liposomal formulations of synthetic MUC1 peptides: effects of encapsulation versus surface display of peptides on immune responses. Bioconjugate Chem. 9, 451-458 (1998).
-
(1998)
Bioconjugate Chem
, vol.9
, pp. 451-458
-
-
Guan, H.1
Budzynski, W.2
Koganty, R.3
-
36
-
-
34047092738
-
Evaluation of a novel vaccine (HVJ-liposome/HSP65 DNA + IL-12 DNA) against tuberculosis using the cynomolgus monkey model of TB
-
Okada M, Kita Y, Nakajima T et al. Evaluation of a novel vaccine (HVJ-liposome/HSP65 DNA + IL-12 DNA) against tuberculosis using the cynomolgus monkey model of TB. Vaccine 25(16), 2990-2993 (2007).
-
(2007)
Vaccine
, vol.25
, Issue.16
, pp. 2990-2993
-
-
Okada, M.1
Kita, Y.2
Nakajima, T.3
-
37
-
-
0032545730
-
Immunogenicity and antitumor activity of a liposomal MUCI peptide-based vaccine
-
Samuel J, Budzynski W, Reddish M et al. Immunogenicity and antitumor activity of a liposomal MUCI peptide-based vaccine. Int. J. Cancer 75, 295-302 (1998).
-
(1998)
Int. J. Cancer
, vol.75
, pp. 295-302
-
-
Samuel, J.1
Budzynski, W.2
Reddish, M.3
-
38
-
-
27244449289
-
Randomized Phase II3 trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer
-
Butts C, Murray N, Maksymiuk A et al. Randomized Phase II3 trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer. J. Clin. Oncol. 23(27), 6674-6681 (2005)
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.27
, pp. 6674-6681
-
-
Butts, C.1
Murray, N.2
Maksymiuk, A.3
-
39
-
-
0031710507
-
Immunopotentiation with low-dose cyclophosphamide in the active specific immunotherapy of cancer
-
Bass K, Mastrangelo M. Immunopotentiation with low-dose cyclophosphamide in the active specific immunotherapy of cancer. Cancer Immunol. Immunother. 47,1-12 (1998).
-
(1998)
Cancer Immunol. Immunother
, vol.47
, pp. 1-12
-
-
Bass, K.1
Mastrangelo, M.2
-
41
-
-
22144483806
-
Vaccination with BLP25 liposome vaccine to treat non-small cell lung and prostate cancers
-
North S, Butts C. Vaccination with BLP25 liposome vaccine to treat non-small cell lung and prostate cancers. Expert Rev. Vaccines 4(3) 249-257 (2005).
-
(2005)
Expert Rev. Vaccines
, vol.4
, Issue.3
, pp. 249-257
-
-
North, S.1
Butts, C.2
-
42
-
-
47649106773
-
L-BLP25) for immunotherapy of epithelial carcinomas. Unpublished. Edmonton, Alberta, Canada. Release date
-
Biomira Inc. Investigator's Brochure for Stimuvax™ BLP25 Liposome Vaccine;, January 30
-
Biomira Inc. Investigator's Brochure for Stimuvax™ (BLP25 Liposome Vaccine; L-BLP25) for immunotherapy of epithelial carcinomas. Unpublished. Edmonton, Alberta, Canada. Release date: January 30, 2006.
-
(2006)
-
-
-
43
-
-
47649129612
-
A liposomal MUCI vaccine for treatment of non-small-cell lung cancer (NSCLC); updated survival results from patients with Stage IIIB disease
-
Orlando, FL, USA, 13-17 May, Abstract 7037
-
Murray N, Butts C, Maksymijuk A, Marshall E, Goss G, Soulieres D. A liposomal MUCI vaccine for treatment of non-small-cell lung cancer (NSCLC); updated survival results from patients with Stage IIIB disease. 2005 ASCO Annual Meeting, Orlando, FL, USA, 13-17 May, 2005 (Abstract 7037).
-
(2005)
2005 ASCO Annual Meeting
-
-
Murray, N.1
Butts, C.2
Maksymijuk, A.3
Marshall, E.4
Goss, G.5
Soulieres, D.6
-
44
-
-
0742324611
-
Phase I immunotherapy with a modified vaccinia virus (MVA) expressing human MUCI as antigen-specific immunotherapy in patients with MUC1-positive advanced cancer
-
Rochlitz C, Figlin R, Squiban P et al. Phase I immunotherapy with a modified vaccinia virus (MVA) expressing human MUCI as antigen-specific immunotherapy in patients with MUC1-positive advanced cancer J. Gene Med. 5, 690-699 (2003).
-
(2003)
J. Gene Med
, vol.5
, pp. 690-699
-
-
Rochlitz, C.1
Figlin, R.2
Squiban, P.3
-
45
-
-
33750586798
-
Phase II study of Belagenpumatucel-L, a transforming growth factor β-2 antisense gene-modified allogeneic tumour cell vaccine in non-small-cell lung cancer (NSCLC)
-
Nemunaitis J, Dillman RO, Schwarzenberger PO et al. Phase II study of Belagenpumatucel-L, a transforming growth factor β-2 antisense gene-modified allogeneic tumour cell vaccine in non-small-cell lung cancer (NSCLC). J. Clin. Oncol. 24(29) 4721-4730 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, Issue.29
, pp. 4721-4730
-
-
Nemunaitis, J.1
Dillman, R.O.2
Schwarzenberger, P.O.3
-
46
-
-
34748815649
-
GSK's antigen-specific cancer immunotherapy program: Pilot results leading to Phase III clinical development
-
Brichard V, Lejeune D. GSK's antigen-specific cancer immunotherapy program: Pilot results leading to Phase III clinical development. Vaccine 25(Suppl. 2), B61-B71 (2007).
-
(2007)
Vaccine
, vol.25
, Issue.SUPPL. 2
-
-
Brichard, V.1
Lejeune, D.2
|