메뉴 건너뛰기




Volumn 20, Issue 3, 2008, Pages 145-155

Pharmacotherapy for methamphetamine dependence: A review of the pathophysiology of methamphetamine addiction and the theoretical basis and efficacy of pharmacotherapeutic interventions

Author keywords

Abstinence syndrome; Methamphetamine dependence; Neurotoxicity; Pathophysiology; Pharmacotherapy; Treatment

Indexed keywords

AMFEBUTAMONE; BACLOFEN; GABAPENTIN; HALOPERIDOL; IMIPRAMINE; METHAMPHETAMINE; MIRTAZAPINE; PAROXETINE; QUETIAPINE; RISPERIDONE; SERTRALINE; TOPIRAMATE; VIGABATRIN;

EID: 47549110206     PISSN: 10401237     EISSN: 15473325     Source Type: Journal    
DOI: 10.1080/10401230802177656     Document Type: Review
Times cited : (68)

References (77)
  • 1
    • 0034882387 scopus 로고    scopus 로고
    • Methamphetamine neurotoxicity: Necrotic and apoptotic mechanisms and relevance to human abuse and treatment
    • Davidson C, Gow AJ, Lee TH, Ellinwood EH. Methamphetamine neurotoxicity: Necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res Brain Res Rev. 2001;36:1-22.
    • (2001) Brain Res Brain Res Rev , vol.36 , pp. 1-22
    • Davidson, C.1    Gow, A.J.2    Lee, T.H.3    Ellinwood, E.H.4
  • 2
    • 20644441994 scopus 로고    scopus 로고
    • Mechanisms of neurotransmitter release by amphetamines: A review
    • Sulzer D, Sonders MS, Poulsen NW, Galli A. Mechanisms of neurotransmitter release by amphetamines: A review. Prog Neurobiol. 2005;75:406-433.
    • (2005) Prog Neurobiol , vol.75 , pp. 406-433
    • Sulzer, D.1    Sonders, M.S.2    Poulsen, N.W.3    Galli, A.4
  • 3
  • 4
    • 0034947639 scopus 로고    scopus 로고
    • Amphetamines: An update on forensic issues
    • Logan BK. Amphetamines: An update on forensic issues. J Anal Toxicol. 2001;25:400-404.
    • (2001) J Anal Toxicol , vol.25 , pp. 400-404
    • Logan, B.K.1
  • 5
    • 33746673822 scopus 로고    scopus 로고
    • Clinical effects and management of methamphetamine abuse
    • Romanelli F, Smith KM. Clinical effects and management of methamphetamine abuse. Pharmacotherapy. 2006;26:1148-1156.
    • (2006) Pharmacotherapy , vol.26 , pp. 1148-1156
    • Romanelli, F.1    Smith, K.M.2
  • 6
    • 0036399169 scopus 로고    scopus 로고
    • Patterns of methamphetamine abuse and their consequences
    • Cho AK, Melega WP. Patterns of methamphetamine abuse and their consequences. J Addict Dis. 2002;21:21-34.
    • (2002) J Addict Dis , vol.21 , pp. 21-34
    • Cho, A.K.1    Melega, W.P.2
  • 7
    • 0141445982 scopus 로고    scopus 로고
    • Speed kills: Cellular and molecular bases of methamphetamine-induced nerve terminal degeneration and neuronal apoptosis
    • Cadet JL, Jayanthi S, Deng X. Speed kills: Cellular and molecular bases of methamphetamine-induced nerve terminal degeneration and neuronal apoptosis. FASEB J. 2003;17:1775-1788,
    • (2003) FASEB J , vol.17 , pp. 1775-1788
    • Cadet, J.L.1    Jayanthi, S.2    Deng, X.3
  • 8
    • 10444275080 scopus 로고    scopus 로고
    • Psychostimulants and vesicle trafficking: A novel mechanism and therapeutic implications
    • Hanson GR, Sandoval V, Riddle E, Fleckenstein AE. Psychostimulants and vesicle trafficking: A novel mechanism and therapeutic implications. Ann NY Acad Sci. 2004;1025:146-150.
    • (2004) Ann NY Acad Sci , vol.1025 , pp. 146-150
    • Hanson, G.R.1    Sandoval, V.2    Riddle, E.3    Fleckenstein, A.E.4
  • 11
    • 0242467879 scopus 로고    scopus 로고
    • Neuroadaptive mechanisms of addiction: Studies on the extended amygdala
    • Koob GF. Neuroadaptive mechanisms of addiction: Studies on the extended amygdala. Eur Neuropsychopharmacol. 2003;13:442-452.
    • (2003) Eur Neuropsychopharmacol , vol.13 , pp. 442-452
    • Koob, G.F.1
  • 12
    • 0033913561 scopus 로고    scopus 로고
    • Neurobiology of addiction. Toward the development of new therapies
    • Koob GF. Neurobiology of addiction. Toward the development of new therapies. Ann NY Acad Sci. 2000;909:170-185.
    • (2000) Ann NY Acad Sci , vol.909 , pp. 170-185
    • Koob, G.F.1
  • 13
    • 0032779911 scopus 로고    scopus 로고
    • The role of the striatopallidal and extended amygdala systems in drug addiction
    • Koob GF. The role of the striatopallidal and extended amygdala systems in drug addiction. Ann NY Acad Sci. 1999;877:445-460.
    • (1999) Ann NY Acad Sci , vol.877 , pp. 445-460
    • Koob, G.F.1
  • 14
    • 0034900862 scopus 로고    scopus 로고
    • Drug addiction: Functional neurotoxicity of the brain reward systems
    • Weiss F, Koob GF. Drug addiction: Functional neurotoxicity of the brain reward systems. Neurotox Res. 2001;3:145-156.
    • (2001) Neurotox Res , vol.3 , pp. 145-156
    • Weiss, F.1    Koob, G.F.2
  • 17
    • 33646342014 scopus 로고    scopus 로고
    • Meth mouth: A review of methamphetamine abuse and its oral manifestations
    • Curtis EK. Meth mouth: A review of methamphetamine abuse and its oral manifestations. Gen Dent. 2006;54:125-129.
    • (2006) Gen Dent , vol.54 , pp. 125-129
    • Curtis, E.K.1
  • 18
    • 0042662779 scopus 로고    scopus 로고
    • Neuropsychological effects of chronic methamphetamine use on neurotransmitters and cognition: A review
    • Nordahl TE, Salo R, Leamon M. Neuropsychological effects of chronic methamphetamine use on neurotransmitters and cognition: A review. J Neuropsychiatry Clin Neurosci. 2003;15:317-325.
    • (2003) J Neuropsychiatry Clin Neurosci , vol.15 , pp. 317-325
    • Nordahl, T.E.1    Salo, R.2    Leamon, M.3
  • 20
    • 0035218082 scopus 로고    scopus 로고
    • Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin
    • Rothman RB, Baumann MH, Dersch CM, Romero DV, Rice KC, Carroll FI, Partilla JS. Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse. 2001;39:32-41.
    • (2001) Synapse , vol.39 , pp. 32-41
    • Rothman, R.B.1    Baumann, M.H.2    Dersch, C.M.3    Romero, D.V.4    Rice, K.C.5    Carroll, F.I.6    Partilla, J.S.7
  • 22
    • 0034100477 scopus 로고    scopus 로고
    • Stimulant psychosis: Symptom profile and acute clinical course
    • Harris D, Batki SL. Stimulant psychosis: Symptom profile and acute clinical course. Am J Addict. 2000;9:28-37.
    • (2000) Am J Addict , vol.9 , pp. 28-37
    • Harris, D.1    Batki, S.L.2
  • 23
    • 0037355892 scopus 로고    scopus 로고
    • Substance abuse and violence: A review of the literature
    • Boles SM, Miotto K. Substance abuse and violence: A review of the literature. Aggr Viol Behav, 2003;8:155-174.
    • (2003) Aggr Viol Behav , vol.8 , pp. 155-174
    • Boles, S.M.1    Miotto, K.2
  • 24
    • 33645816792 scopus 로고    scopus 로고
    • Methamphetamine use and violence
    • Sommers I, Baskin D. Methamphetamine use and violence. J Drug Issues, 2006;36:77-96.
    • (2006) J Drug Issues , vol.36 , pp. 77-96
    • Sommers, I.1    Baskin, D.2
  • 25
    • 33644613112 scopus 로고    scopus 로고
    • Methamphetamine use, self-reported violent crime, and recidivism among offenders in California who abuse substances
    • Cartier J, Farabee D, Prendergast ML. Methamphetamine use, self-reported violent crime, and recidivism among offenders in California who abuse substances. J Interpers Viol. 2006;21:435-445.
    • (2006) J Interpers Viol , vol.21 , pp. 435-445
    • Cartier, J.1    Farabee, D.2    Prendergast, M.L.3
  • 26
    • 0033066064 scopus 로고    scopus 로고
    • Amphetamine withdrawal: I. Reliability, validity and factor structure of a measure
    • Srisurapanont M, Jarusuraisin N, Jittiwutikan J. Amphetamine withdrawal: I. Reliability, validity and factor structure of a measure. Aust NZ J Psychiatry. 1999;33:89-93.
    • (1999) Aust NZ J Psychiatry , vol.33 , pp. 89-93
    • Srisurapanont, M.1    Jarusuraisin, N.2    Jittiwutikan, J.3
  • 27
    • 23744495312 scopus 로고    scopus 로고
    • Depression and other psychological health problems among methamphetamine dependent patients in treatment: Implications for assessment and treatment outcomes
    • Dyer KR, Cruickshank CC. Depression and other psychological health problems among methamphetamine dependent patients in treatment: Implications for assessment and treatment outcomes. Aust Psychologist, 2003;40:96-108.
    • (2003) Aust Psychologist , vol.40 , pp. 96-108
    • Dyer, K.R.1    Cruickshank, C.C.2
  • 32
    • 0037367190 scopus 로고    scopus 로고
    • Methamphetamine dependence is associated with neurocognitive impairment in the initial phases of abstinence
    • Kalechstein AD, Newton TF, Green M. Methamphetamine dependence is associated with neurocognitive impairment in the initial phases of abstinence. J Neuropsychiatry Clin Neurosci. 2003;15:215-220.
    • (2003) J Neuropsychiatry Clin Neurosci , vol.15 , pp. 215-220
    • Kalechstein, A.D.1    Newton, T.F.2    Green, M.3
  • 34
    • 3042515440 scopus 로고    scopus 로고
    • The effect of relapse on cognition in abstinent methamphetamine abusers
    • Simon SL, Dacey J, Glynn S, Rawson R, Ling W. The effect of relapse on cognition in abstinent methamphetamine abusers. J Subst Abuse Treat. 2004;27:59-66.
    • (2004) J Subst Abuse Treat , vol.27 , pp. 59-66
    • Simon, S.L.1    Dacey, J.2    Glynn, S.3    Rawson, R.4    Ling, W.5
  • 35
    • 10444246578 scopus 로고    scopus 로고
    • Smaller subcortical volumes and cognitive deficits in children with prenatal methamphetamine exposure
    • Chang L, Smith LM, LoPresti C, Yonekura ML, Kuo J, Walot I, Ernst T. Smaller subcortical volumes and cognitive deficits in children with prenatal methamphetamine exposure. Psychiatry Res. 2004;132:95-106.
    • (2004) Psychiatry Res , vol.132 , pp. 95-106
    • Chang, L.1    Smith, L.M.2    LoPresti, C.3    Yonekura, M.L.4    Kuo, J.5    Walot, I.6    Ernst, T.7
  • 36
    • 0034724360 scopus 로고    scopus 로고
    • Evidence for long-term neurotoxicity associated with methamphetamine abuse: A 1H MRS study
    • Ernst T, Chang L, Leonido-Yee M, Speck O. Evidence for long-term neurotoxicity associated with methamphetamine abuse: A 1H MRS study. Neurology. 2000;54:1344-1349.
    • (2000) Neurology , vol.54 , pp. 1344-1349
    • Ernst, T.1    Chang, L.2    Leonido-Yee, M.3    Speck, O.4
  • 37
    • 19944433232 scopus 로고    scopus 로고
    • Woods SP, Rippeth JD, Conover E, Gongvatana A, Gonzalez R, Carey CL, Cherner M, Heaton RK, Grant I. HIV Neurobehavioral Research Center Group: Deficient strategic control of verbal encoding and retrieval in individuals with methamphetamine dependence. Neuropsychology. 2005;19:35-43.
    • Woods SP, Rippeth JD, Conover E, Gongvatana A, Gonzalez R, Carey CL, Cherner M, Heaton RK, Grant I. HIV Neurobehavioral Research Center Group: Deficient strategic control of verbal encoding and retrieval in individuals with methamphetamine dependence. Neuropsychology. 2005;19:35-43.
  • 39
    • 33646380088 scopus 로고    scopus 로고
    • From genes to aggressive behavior: The role of serotonergic system
    • Popova NK. From genes to aggressive behavior: The role of serotonergic system. Bioessays 2006;28:495-503.
    • (2006) Bioessays , vol.28 , pp. 495-503
    • Popova, N.K.1
  • 40
    • 0242297802 scopus 로고    scopus 로고
    • Alcohol and violence and the possible role of serotonin
    • Badawy AA. Alcohol and violence and the possible role of serotonin. Crim Behav Mental Health. 2003;13:31-44.
    • (2003) Crim Behav Mental Health , vol.13 , pp. 31-44
    • Badawy, A.A.1
  • 41
    • 0042161744 scopus 로고    scopus 로고
    • Violence and serotonin: Influence of impulse control, affect regulation, and social functioning
    • Krakowski M: Violence and serotonin: Influence of impulse control, affect regulation, and social functioning. J Neuropsychiatry Clin Neurosci. 2003;15:294-305.
    • (2003) J Neuropsychiatry Clin Neurosci , vol.15 , pp. 294-305
    • Krakowski, M.1
  • 48
    • 33748486897 scopus 로고    scopus 로고
    • Fatal amphetamine-associated cardiotoxicity and its medicolegal implications
    • Jacobs W. Fatal amphetamine-associated cardiotoxicity and its medicolegal implications. Am J Forensic Med Pathol. 2006;27:156-160.
    • (2006) Am J Forensic Med Pathol , vol.27 , pp. 156-160
    • Jacobs, W.1
  • 49
    • 33644835175 scopus 로고    scopus 로고
    • The methamphetamine epidemic: Implications for HIV prevention and treatment
    • 2005;2:194-199
    • Colfax G, Shoptaw S. The methamphetamine epidemic: Implications for HIV prevention and treatment. Curr HIV/AIDS Rep. 2005;2:194-199.
    • Curr HIV/AIDS Rep
    • Colfax, G.1    Shoptaw, S.2
  • 50
    • 0027968036 scopus 로고
    • The treatment of stimulant dependence
    • Schuckit MA. The treatment of stimulant dependence. Addiction. 1994;89:1559-1563.
    • (1994) Addiction , vol.89 , pp. 1559-1563
    • Schuckit, M.A.1
  • 51
    • 0018964318 scopus 로고
    • Increased self-administration of d-amphetamine after destruction of 5-hydroxytryptaminergic neurons
    • Lyness WH, Friedle NM, Moore KE. Increased self-administration of d-amphetamine after destruction of 5-hydroxytryptaminergic neurons. Pharmacol Biochem Behav. 1980;12:937-941.
    • (1980) Pharmacol Biochem Behav , vol.12 , pp. 937-941
    • Lyness, W.H.1    Friedle, N.M.2    Moore, K.E.3
  • 55
    • 47549098903 scopus 로고    scopus 로고
    • Batki SL, Moon J, Bradley M, Hersh D, Smolar S, Mengis M, Delucchi K, Sexe D, Bennett S, Lefkowitz E, Chu W, Morello L, Jacob P, Jones RT. Fluoxetine in methamphetamine dependence - a controlled trial: Preliminary analysis. NIDA Research Monograph, Number 180 [Printed in 2000b]. Problems of Drug Dependence 1999: Proceedings of the 61st Annual Scientific Meeting The College on Problems of Drug Dependence, Inc.
    • Batki SL, Moon J, Bradley M, Hersh D, Smolar S, Mengis M, Delucchi K, Sexe D, Bennett S, Lefkowitz E, Chu W, Morello L, Jacob P, Jones RT. Fluoxetine in methamphetamine dependence - a controlled trial: Preliminary analysis. NIDA Research Monograph, Number 180 [Printed in 2000b]. Problems of Drug Dependence 1999: Proceedings of the 61st Annual Scientific Meeting The College on Problems of Drug Dependence, Inc.
  • 57
    • 47549111442 scopus 로고    scopus 로고
    • Treatment of methamphetamine cravings with bupropion: A case report
    • Berigan TR, Russell ML. Treatment of methamphetamine cravings with bupropion: A case report. Prim Care Companion J Clin Psychiatry. 2001;3:267-268.
    • (2001) Prim Care Companion J Clin Psychiatry , vol.3 , pp. 267-268
    • Berigan, T.R.1    Russell, M.L.2
  • 59
    • 24944569255 scopus 로고    scopus 로고
    • Methylphenidate effective in treating amphetamine abusers with no other psychiatric disorder
    • Laqueille X, Dervaux A, El Omari F, Kanit M, Bayle FJ. Methylphenidate effective in treating amphetamine abusers with no other psychiatric disorder. Eur Psychiatry. 2005;20:456-457.
    • (2005) Eur Psychiatry , vol.20 , pp. 456-457
    • Laqueille, X.1    Dervaux, A.2    El Omari, F.3    Kanit, M.4    Bayle, F.J.5
  • 61
    • 0036708074 scopus 로고    scopus 로고
    • The effects of acute haloperidol or risperidone on subjective responses to methamphetamine in healthy volunteers
    • Wachtel SR, Ortengren A, de Wit H. The effects of acute haloperidol or risperidone on subjective responses to methamphetamine in healthy volunteers. Drug Alcohol Depend. 2002;68:23-33.
    • (2002) Drug Alcohol Depend , vol.68 , pp. 23-33
    • Wachtel, S.R.1    Ortengren, A.2    de Wit, H.3
  • 62
    • 11344260664 scopus 로고    scopus 로고
    • Potential benefits of quetiapine in the treatment of substance dependence disorders
    • Sattar SP, Bhatia SC, Petty F. Potential benefits of quetiapine in the treatment of substance dependence disorders. J Psychiatry Neurosci. 2004;29:452-457.
    • (2004) J Psychiatry Neurosci , vol.29 , pp. 452-457
    • Sattar, S.P.1    Bhatia, S.C.2    Petty, F.3
  • 63
    • 33749498310 scopus 로고    scopus 로고
    • Randomized placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependence
    • Heinzerling KG, Shoptaw S, Peck JA, Yang X, Liu J, Roll J, Ling W. Randomized placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependence. Drug Alcohol Depend. 2006;85:177-184.
    • (2006) Drug Alcohol Depend , vol.85 , pp. 177-184
    • Heinzerling, K.G.1    Shoptaw, S.2    Peck, J.A.3    Yang, X.4    Liu, J.5    Roll, J.6    Ling, W.7
  • 64
    • 10844262539 scopus 로고    scopus 로고
    • Safety and efficacy of gamma-vinyl GABA (GVG) for the treatment of methamphetamine and/or cocaine addiction
    • Brodie JD, Figueroa E, Laska EM, Dewey SL. Safety and efficacy of gamma-vinyl GABA (GVG) for the treatment of methamphetamine and/or cocaine addiction. Synapse 2005;55:122-125.
    • (2005) Synapse , vol.55 , pp. 122-125
    • Brodie, J.D.1    Figueroa, E.2    Laska, E.M.3    Dewey, S.L.4
  • 68
    • 33845641232 scopus 로고    scopus 로고
    • Effects of topiramate on methamphetamine-induced changes in attentional and perceptual motor skills of cognition in recently abstinent methamphetamine-dependent individuals
    • Johnson BA, Roache JD, Ait-Daoud N, Wells LT, Wallace CL, Dawes MA, Liu L, Wang XQ. Effects of topiramate on methamphetamine-induced changes in attentional and perceptual motor skills of cognition in recently abstinent methamphetamine-dependent individuals. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31:123-130.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 123-130
    • Johnson, B.A.1    Roache, J.D.2    Ait-Daoud, N.3    Wells, L.T.4    Wallace, C.L.5    Dawes, M.A.6    Liu, L.7    Wang, X.Q.8
  • 69
    • 3142680841 scopus 로고    scopus 로고
    • Pharmacotherapies for problematic psychostimulant use: A review of current research
    • Shearer J, Gowing LR. Pharmacotherapies for problematic psychostimulant use: A review of current research. Drug Alcohol Rev. 2004;23:203-211.
    • (2004) Drug Alcohol Rev , vol.23 , pp. 203-211
    • Shearer, J.1    Gowing, L.R.2
  • 71
    • 47549083983 scopus 로고    scopus 로고
    • Information on Clinical Trials and Human Research Studies. Available at, Accessed July 10, 2007
    • Information on Clinical Trials and Human Research Studies. Available at http://www.clinicaltrials.gov/. Accessed July 10, 2007.
  • 77
    • 33846088516 scopus 로고    scopus 로고
    • Improvement in measures of psychological distress amongst amphetamine misusers treated with brief cognitive-behavioral therapy (CBT)
    • Feeney GFX, Connor JP, Young R, Tucker J, McPherson A. Improvement in measures of psychological distress amongst amphetamine misusers treated with brief cognitive-behavioral therapy (CBT). Addict Behav. 2005;31:1833-1843.
    • (2005) Addict Behav , vol.31 , pp. 1833-1843
    • Feeney, G.F.X.1    Connor, J.P.2    Young, R.3    Tucker, J.4    McPherson, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.