Flux control exerted by mitochondrial outer membrane carnitine palmitoyltransferase over β-oxidation, ketogenesis and tricarboxylic acid cycle activity in hepatocytes isolated from rats in different metabolic states

Biochemical Journal

Volumn 317, Issue 3, 1996, Pages 791-795

  Drynan, Lesley ^a,c   Quant, Patti A ^a,b,d   Zammit, Victor A ^a  

^a HANNAH RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^d GREAT ORMOND STREET HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLCARNITINE; CARNITINE PALMITOYLTRANSFERASE; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOHYDRATE METABOLISM; CELL METABOLISM; CITRIC ACID CYCLE; CONTROLLED STUDY; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; FEMALE; KETOGENESIS; LIVER CELL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CARNITINE O-PALMITOYLTRANSFERASE; CITRIC ACID CYCLE; FEMALE; FOOD; INSULIN; INTRACELLULAR MEMBRANES; KETONE BODIES; MITOCHONDRIA, LIVER; OXIDATION-REDUCTION; RATS; RATS, WISTAR; STARVATION;

ANIMALIA;

EID: 0029793298     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3170791     Document Type: Article

References (34)

1. Zammit, V. A. (1981) Trends Biochem. Sci. 6, 46-49
2. Zammit, V. A. (1995) Diabetes Rev. 2, 132-155
3. McGarry, J. D., Mannaerts, G. P. and Foster, D. W. (1977) J. Clin. Invest. 60, 265-270
4. Cook, G. A., Otto, D. A. and Cornell, N. W. (1980) Biochem. J. 192, 955-958
5. Ontko, J. A. and Johns, M. L. (1980) Biochem. J. 192, 959-962
6. Cook, G. A. (1984) J. Biol. Chem. 259, 12030-12033
7. Drynan, L. Quant, P. A. and Zammit, V. A. (1996) Biochem. J., in the press
8. Kolodziej, M. P., Crilly, P. J., Corstorphine, C. G. and Zammit, V. A. (1992) Biochem. J. 282, 415-421
9. Grantham, B. D. and Zammit, V. A. (1988) Biochem. J. 249, 409-414
10. Grantham, B. D. and Zammit, V. A. (1986) Biochem. J. 239, 485-488
11. Moir, A. M. B. and Zammit, V. A. (1993) Biochem. J. 289, 49-55
12. Moir, A. M. B. and Zammit, V. A. (1994) Biochem. J. 304, 177-182
13. Moir, A. M. B. and Zammit, V. A. (1994) Trends Biochem. Sci. 19, 313-317
14. Casals, N., Roca, N., Guerrero, M., Gil-Gomez, G., Ayte, J., Ciudad, C. J. and Hegardt, F. G. (1992) Biochem. J. 283, 261-264
15. Serra, D., Casals, N., Asino, G., Royo, T., Ciudad, C. J. and Hegardt, F. G. (1993) Arch. Biochem. Biophys. 307, 40-45
16. Hegardt, F. G. (1995) Biochem. Soc. Trans. 23, 486-490
17. Quant, P. A. (1990) Biochem. Soc. Trans. 18, 994-995
18. Groen, A. K., van der Meer, R., Westerhoff, H. V., Wanders, R. J. A., Akerboom, T. P. M. and Tager, J. M. (1981) in Metabolic Compartmentation (Sies, H., ed.), pp. 9-37, Elsevier, Amsterdam
19. Seglen, P. O. (1973) Methods Cell Biol. 13, 30-83
20. Zammit, V. A. (1995) Biochem. J. 312, 57-62
21. Krebs, H. A. and Henseleit, K. (1932) Hoppe-Seylers Z. Physiol. Chem. 210, 33-66
22. Boon, M. R. and Zammit, V. A. (1988) Biochem. J. 249, 645-652
23. Guzman, M., Kolodziej, M. P., Caldwell, A. M., Corstorphine, C. G. and Zammit, V. A. (1994) Biochem. J. 300, 693-699
24. Small, J. R. (1993) Biochem. J. 296, 423-433
25. Kiorpes, T. C., Hoerr, D., Ho, W., Weaner, L. E., Inman, M. G. and Tutwiler, G. F. (1984) J. Biol. Chem. 259, 9750-9755
26. Guzman, M. and Gellen, M. J. H. (1992) Biochem. J. 287, 487-492
27. Chatterjee, B., Song, C. S., Kim, J. M. and Roy, A. K. (1988) Biochemistry 27, 9000-9006
28. Lilly, K., Sugaisky, G. E., Umeda, P. K. and Bieber, L. L. (1990) Arch. Biochem. Biophys. 280, 167-174
29. Broadway, N. M. and Saggerson, E. D. (1995) Biochem. Soc. Trans. 23, 490-494
30. Garland, P. B., Shepherd, D., Nicholls, D. G. and Ontko, J. (1968) Adv. Enzyme Regul. 6, 3-30
31. Lopes-Cardozo, M., Mulder, L., Van Vugt, F., Hermans, P. G. and van den Bergh, S. (1975) Mol. Cell. Biochem. 9, 155-173
32. Des Rosier, C., David, F., Garneau, M. and Brunengraber, H. (1991) J. Biol. Chem. 266, 1574-1578
33. Sugden, M. C., Watts, D. I., Palmer, T. N. and Myles, D. D. (1983) Biochem. Int. 7, 329-337
34. Katz, J. and McGarry, J. D. (1984) J. Clin. Invest. 74, 1901-1909