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Volumn 22, Issue 7, 2008, Pages 1354-1360

Bruton's tyrosine kinase is not essential for Bcr-Abl-mediated transformation of lymphoid or myeloid cells

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; BRUTON TYROSINE KINASE; IMATINIB; PHOSPHOTRANSFERASE INHIBITOR; SHORT HAIRPIN RNA;

EID: 47549101393     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2008.126     Document Type: Article
Times cited : (10)

References (34)
  • 1
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, Ford JM et al Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001; 344: 1031-1037.
    • (2001) N Engl J Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3    Peng, B.4    Buchdunger, E.5    Ford, J.M.6
  • 2
    • 0025117392 scopus 로고
    • Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome
    • Daley GQ, Van Etten RA, Baltimore D. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science 1990; 247: 824-830.
    • (1990) Science , vol.247 , pp. 824-830
    • Daley, G.Q.1    Van Etten, R.A.2    Baltimore, D.3
  • 3
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • Lugo TG, Pendergast AM, Muller AJ, Witte ON. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science 1990; 247: 1079-1082.
    • (1990) Science , vol.247 , pp. 1079-1082
    • Lugo, T.G.1    Pendergast, A.M.2    Muller, A.J.3    Witte, O.N.4
  • 4
    • 0033987718 scopus 로고    scopus 로고
    • Reversibility of acute B-cell leukaemia induced by BCR-ABL1
    • Huettner CS, Zhang P, Van Etten RA, Tenen DG. Reversibility of acute B-cell leukaemia induced by BCR-ABL1. Nat Genet 2000; 24: 57-60.
    • (2000) Nat Genet , vol.24 , pp. 57-60
    • Huettner, C.S.1    Zhang, P.2    Van Etten, R.A.3    Tenen, D.G.4
  • 5
    • 33746934638 scopus 로고    scopus 로고
    • Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib
    • Griswold IJ, MacPartlin M, Bumm T, Goss VL, O'Hare T, Lee KA et al Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib. Mol Cell Biol 2006; 26: 6082-6093.
    • (2006) Mol Cell Biol , vol.26 , pp. 6082-6093
    • Griswold, I.J.1    MacPartlin, M.2    Bumm, T.3    Goss, V.L.4    O'Hare, T.5    Lee, K.A.6
  • 6
    • 0036604985 scopus 로고    scopus 로고
    • New insights into the regulation and functions of Tec family tyrosine kinases in the immune system
    • Miller AT, Berg LJ. New insights into the regulation and functions of Tec family tyrosine kinases in the immune system. Curr Opin Immunol 2002; 14: 331-340.
    • (2002) Curr Opin Immunol , vol.14 , pp. 331-340
    • Miller, A.T.1    Berg, L.J.2
  • 7
    • 0033696009 scopus 로고    scopus 로고
    • Tec kinases: A family with multiple roles in immunity
    • Yang WC, Collette Y, Nunes JA, Olive D. Tec kinases: A family with multiple roles in immunity. Immunity 2000; 12: 373-382.
    • (2000) Immunity , vol.12 , pp. 373-382
    • Yang, W.C.1    Collette, Y.2    Nunes, J.A.3    Olive, D.4
  • 8
    • 0028060150 scopus 로고
    • Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement
    • Saouaf SJ, Mahajan S, Rowley RB, Kut SA, Fargnoli J, Burkhardt AL et al. Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement. Proc Natl Acad Sci USA 1994; 91 9524-9528.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9524-9528
    • Saouaf, S.J.1    Mahajan, S.2    Rowley, R.B.3    Kut, S.A.4    Fargnoli, J.5    Burkhardt, A.L.6
  • 9
    • 0030038840 scopus 로고    scopus 로고
    • Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
    • Rawlings DJ, Scharenberg AM, Park H, Wahl MI, Lin S, Kato RM et al Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases. Science 1996; 271: 822-825.
    • (1996) Science , vol.271 , pp. 822-825
    • Rawlings, D.J.1    Scharenberg, A.M.2    Park, H.3    Wahl, M.I.4    Lin, S.5    Kato, R.M.6
  • 10
    • 0027980301 scopus 로고
    • Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction
    • Cheng G, Ye ZS, Baltimore D. Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction. Proc Natl Acad Sci USA 1994; 91: 8152-8155.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8152-8155
    • Cheng, G.1    Ye, Z.S.2    Baltimore, D.3
  • 11
    • 0345447618 scopus 로고    scopus 로고
    • Function of Bruton's tyrosine kinase during B cell development is partially independent of its catalytic activity
    • Middendorp S, Dingjan GM, Maas A, Dahlenborg K, Hendriks RW. Function of Bruton's tyrosine kinase during B cell development is partially independent of its catalytic activity. J Immunol 2003; 171: 5988-5996.
    • (2003) J Immunol , vol.171 , pp. 5988-5996
    • Middendorp, S.1    Dingjan, G.M.2    Maas, A.3    Dahlenborg, K.4    Hendriks, R.W.5
  • 12
    • 0033695960 scopus 로고    scopus 로고
    • Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex
    • Guo B, Kato RM, Garcia-Lloret M, Wahl MI, Rawlings DJ. Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex. Immunity 2000; 13: 243-253.
    • (2000) Immunity , vol.13 , pp. 243-253
    • Guo, B.1    Kato, R.M.2    Garcia-Lloret, M.3    Wahl, M.I.4    Rawlings, D.J.5
  • 13
    • 0027962645 scopus 로고
    • Two binding orientations for peptides to the Src SH3 domain: Development of a general model for SH3-ligand interactions
    • Feng S, Chen JK, Yu H, Simon JA, Schreiber SL. Two binding orientations for peptides to the Src SH3 domain: Development of a general model for SH3-ligand interactions. Science 1994; 266: 1241-1247.
    • (1994) Science , vol.266 , pp. 1241-1247
    • Feng, S.1    Chen, J.K.2    Yu, H.3    Simon, J.A.4    Schreiber, S.L.5
  • 15
    • 22344440682 scopus 로고    scopus 로고
    • Mimicry of a constitutively active pre-B cell receptor in acute lymphoblastic leukemia cells
    • Feldhahn N, Klein F, Mooster JL, Hadweh P, Sprangers M, Wartenberg M et al. Mimicry of a constitutively active pre-B cell receptor in acute lymphoblastic leukemia cells. J Exp Med 2005; 201: 1837-1852.
    • (2005) J Exp Med , vol.201 , pp. 1837-1852
    • Feldhahn, N.1    Klein, F.2    Mooster, J.L.3    Hadweh, P.4    Sprangers, M.5    Wartenberg, M.6
  • 16
    • 33744489570 scopus 로고    scopus 로고
    • Identification of genes involved in imatinib resistance in CML: A gene-expression profiling approach
    • Villuendas R, Steegmann JL, Pollan M, Tracey L, Granda A, Fernandez-Ruiz E et al. Identification of genes involved in imatinib resistance in CML: A gene-expression profiling approach. Leukemia 2006; 20 1047-1054.
    • (2006) Leukemia , vol.20 , pp. 1047-1054
    • Villuendas, R.1    Steegmann, J.L.2    Pollan, M.3    Tracey, L.4    Granda, A.5    Fernandez-Ruiz, E.6
  • 18
    • 0037115644 scopus 로고    scopus 로고
    • Activity of the Bcr-Abl kinase inhibitor PD180970 against clinically relevant Bcr-Abl isoforms that cause resistance to imatinib mesylate (Gleevec, STI571)
    • La Rosee P, Corbin AS, Stoffregen EP, Deininger MW, Druker BJ. Activity of the Bcr-Abl kinase inhibitor PD180970 against clinically relevant Bcr-Abl isoforms that cause resistance to imatinib mesylate (Gleevec, STI571). Cancer Res 2002; 62: 7149-7153.
    • (2002) Cancer Res , vol.62 , pp. 7149-7153
    • La Rosee, P.1    Corbin, A.S.2    Stoffregen, E.P.3    Deininger, M.W.4    Druker, B.J.5
  • 19
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear WS, Nolan GP, Scott ML, Baltimore D. Production of high-titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA 1993; 90: 8392-8396.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 20
    • 47549103148 scopus 로고    scopus 로고
    • Honigberg LA, Smith AM, Chen J, Thiemann P, Verner E, Renschler M. Targeting Btk in lymphoma: PCI-32765 inhibits tumor growth in mouse lymphoma models and a fluorescent analog of PCI-32765 is an active-site probe that enables assessment of Btk inhibition in vivo. Session Type: Poster Session, Board #746-1. Blood 2007 16 November 2007; 2007. p. 475A.
    • Honigberg LA, Smith AM, Chen J, Thiemann P, Verner E, Renschler M. Targeting Btk in lymphoma: PCI-32765 inhibits tumor growth in mouse lymphoma models and a fluorescent analog of PCI-32765 is an active-site probe that enables assessment of Btk inhibition in vivo. Session Type: Poster Session, Board #746-1. Blood 2007 16 November 2007; 2007. p. 475A.
  • 21
    • 0032533620 scopus 로고    scopus 로고
    • Bcr-Abl efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: A novel model for chronic myelogenous leukemia
    • Zhang X, Ren R. Bcr-Abl efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: A novel model for chronic myelogenous leukemia. Blood 1998; 92: 3829-3840.
    • (1998) Blood , vol.92 , pp. 3829-3840
    • Zhang, X.1    Ren, R.2
  • 23
    • 0023410428 scopus 로고
    • In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome
    • McLaughlin J, Chianese E, Witte ON. In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome. Proc Natl Acad Sci USA 1987; 84: 6558-6562.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 6558-6562
    • McLaughlin, J.1    Chianese, E.2    Witte, O.N.3
  • 24
    • 3142676436 scopus 로고    scopus 로고
    • Overriding imatinib resistance with a novel ABL kinase inhibitor
    • Shah NP, Tran C, Lee FY, Chen P, Norris D, Sawyers CL. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 2004; 305: 399-401.
    • (2004) Science , vol.305 , pp. 399-401
    • Shah, N.P.1    Tran, C.2    Lee, F.Y.3    Chen, P.4    Norris, D.5    Sawyers, C.L.6
  • 25
    • 0042170248 scopus 로고    scopus 로고
    • Autoinhibition of Bcr-Abl through its SH3 domain
    • Smith KM, Yacobi R, Van Etten RA. Autoinhibition of Bcr-Abl through its SH3 domain. Mol Cell 2003; 12: 27-37.
    • (2003) Mol Cell , vol.12 , pp. 27-37
    • Smith, K.M.1    Yacobi, R.2    Van Etten, R.A.3
  • 26
    • 0037085785 scopus 로고    scopus 로고
    • Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
    • Talpaz M, Silver RT, Druker BJ, Goldman JM, Gambacorti-Passerini C, Guilhot F et al. Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study. Blood 2002; 99: 1928-1937.
    • (2002) Blood , vol.99 , pp. 1928-1937
    • Talpaz, M.1    Silver, R.T.2    Druker, B.J.3    Goldman, J.M.4    Gambacorti-Passerini, C.5    Guilhot, F.6
  • 27
    • 0037093092 scopus 로고    scopus 로고
    • Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
    • Sawyers CL, Hochhaus A, Feldman E, Goldman JM, Miller CB, Ottmann OG et al. Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood 2002; 99: 3530-3539.
    • (2002) Blood , vol.99 , pp. 3530-3539
    • Sawyers, C.L.1    Hochhaus, A.2    Feldman, E.3    Goldman, J.M.4    Miller, C.B.5    Ottmann, O.G.6
  • 28
    • 0037105560 scopus 로고    scopus 로고
    • A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias
    • Ottmann OG, Druker BJ, Sawyers CL, Goldman JM, Reiffers J, Silver RT et al. A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias. Blood 2002; 100: 1965-1971.
    • (2002) Blood , vol.100 , pp. 1965-1971
    • Ottmann, O.G.1    Druker, B.J.2    Sawyers, C.L.3    Goldman, J.M.4    Reiffers, J.5    Silver, R.T.6
  • 29
    • 1342287959 scopus 로고    scopus 로고
    • High incidence of BCR-ABL kinase domain mutations and absence of mutations of the PDGFR and KIT activation loops in CML patients with secondary resistance to imatinib
    • Al-Ali HK, Heinrich MC, Lange T, Krahl R, Mueller M, Muller C et al High incidence of BCR-ABL kinase domain mutations and absence of mutations of the PDGFR and KIT activation loops in CML patients with secondary resistance to imatinib. Hematol J 2004; 5: 55-60.
    • (2004) Hematol J , vol.5 , pp. 55-60
    • Al-Ali, H.K.1    Heinrich, M.C.2    Lange, T.3    Krahl, R.4    Mueller, M.5    Muller, C.6
  • 30
    • 0037045583 scopus 로고    scopus 로고
    • BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: A prospective study
    • von Bubnoff N, Schneller F, Peschel C, Duyster J. BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: A prospective study. Lancet 2002; 359: 487-491.
    • (2002) Lancet , vol.359 , pp. 487-491
    • von Bubnoff, N.1    Schneller, F.2    Peschel, C.3    Duyster, J.4
  • 31
    • 0036850514 scopus 로고    scopus 로고
    • Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy
    • Hochhaus A, Kreil S, Corbin AS, La Rosee P, Muller MC, Lahaye T et al Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy. Leukemia 2002; 16: 2190-2196.
    • (2002) Leukemia , vol.16 , pp. 2190-2196
    • Hochhaus, A.1    Kreil, S.2    Corbin, A.S.3    La Rosee, P.4    Muller, M.C.5    Lahaye, T.6
  • 32
    • 0001686739 scopus 로고    scopus 로고
    • Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
    • Shah NP, Nicoll JM, Nagar B, Gorre ME, Paquette RL, Kuriyan J et al Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell 2002; 2: 117-125.
    • (2002) Cancer Cell , vol.2 , pp. 117-125
    • Shah, N.P.1    Nicoll, J.M.2    Nagar, B.3    Gorre, M.E.4    Paquette, R.L.5    Kuriyan, J.6
  • 33
    • 0037045589 scopus 로고    scopus 로고
    • Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: A gene-expression study
    • Hofmann WK, de Vos S, Elashoff D, Gschaidmeier H, Hoelzer D, Koeffler HP et al. Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: A gene-expression study. Lancet 2002; 359: 481-486.
    • (2002) Lancet , vol.359 , pp. 481-486
    • Hofmann, W.K.1    de Vos, S.2    Elashoff, D.3    Gschaidmeier, H.4    Hoelzer, D.5    Koeffler, H.P.6
  • 34
    • 0033515450 scopus 로고    scopus 로고
    • Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano- beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide]
    • Mahajan S, Ghosh S, Sudbeck EA, Zheng Y, Downs S, Hupke M et al. Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano- beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide]. J Biol Chem 1999; 274: 9587-9599.
    • (1999) J Biol Chem , vol.274 , pp. 9587-9599
    • Mahajan, S.1    Ghosh, S.2    Sudbeck, E.A.3    Zheng, Y.4    Downs, S.5    Hupke, M.6


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