메뉴 건너뛰기




Volumn 22, Issue 7, 2008, Pages 1452-1453

Tandutinib inhibits FMS receptor signalling, and macrophage and osteoclast formation in vitro

Author keywords

[No Author keywords available]

Indexed keywords

4 [6 METHOXY 7 [3 (1 PIPERIDINYL)PROPOXY] 4 QUINAZOLINYL] 1 PIPERAZINECARBOXYLIC ACID (4 ISOPROPOXYPHENYL)AMIDE; ASPARTIC ACID; COLONY STIMULATING FACTOR RECEPTOR; IMATINIB; VALINE;

EID: 47549099826     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2405085     Document Type: Letter
Times cited : (6)

References (8)
  • 1
    • 33845240584 scopus 로고    scopus 로고
    • Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: Safety, pharmacokinetics, and pharmacodynamics
    • DeAngelo DJ, Stone RM, Heaney ML, Nimer SD, Paquette RL, Klisovic RB et al. Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: Safety, pharmacokinetics, and pharmacodynamics. Blood 2006; 108: 3674-3681.
    • (2006) Blood , vol.108 , pp. 3674-3681
    • DeAngelo, D.J.1    Stone, R.M.2    Heaney, M.L.3    Nimer, S.D.4    Paquette, R.L.5    Klisovic, R.B.6
  • 2
    • 0036124762 scopus 로고    scopus 로고
    • I receptor tyrosine kinases: Role in leukaemogenesis
    • Reilly JT. Class III receptor tyrosine kinases: Role in leukaemogenesis. Br J Haematol 2002; 116: 744-757.
    • (2002) Br J Haematol , vol.116 , pp. 744-757
    • Class II, R.J.T.1
  • 3
    • 0013102301 scopus 로고    scopus 로고
    • CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML)
    • Kelly LM, Yu JC, Boulton CL, Apatira M, Li J, Sullivan CM et al. CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML). Cancer Cell 2002; 1: 421-432.
    • (2002) Cancer Cell , vol.1 , pp. 421-432
    • Kelly, L.M.1    Yu, J.C.2    Boulton, C.L.3    Apatira, M.4    Li, J.5    Sullivan, C.M.6
  • 4
    • 33845214085 scopus 로고    scopus 로고
    • A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model
    • Ohno H, Kubo K, Murooka H, Kobayashi Y, Nishitoba T, Shibuya M et al. A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model. Mol Cancer Ther 2006; 5: 2634-2643.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2634-2643
    • Ohno, H.1    Kubo, K.2    Murooka, H.3    Kobayashi, Y.4    Nishitoba, T.5    Shibuya, M.6
  • 5
    • 9144274970 scopus 로고    scopus 로고
    • SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model
    • Murray LJ, Abrams TJ, Long KR, Ngai TJ, Olson LM, Hong W et al. SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model. Clin Exp Metastasis 2003; 20: 757-766.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 757-766
    • Murray, L.J.1    Abrams, T.J.2    Long, K.R.3    Ngai, T.J.4    Olson, L.M.5    Hong, W.6
  • 6
    • 31044433663 scopus 로고    scopus 로고
    • Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis
    • Condeelis J, Pollard JW. Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis. Cell 2006; 124: 263-266.
    • (2006) Cell , vol.124 , pp. 263-266
    • Condeelis, J.1    Pollard, J.W.2
  • 7
    • 7244251613 scopus 로고    scopus 로고
    • Variable sensitivity of FLT3 activation loop mutations to the small molecule tyrosine kinase inhibitor MLN518
    • Clark JJ, Cools J, Curley DP, Yu JC, Lokker NA, Giese NA et al. Variable sensitivity of FLT3 activation loop mutations to the small molecule tyrosine kinase inhibitor MLN518. Blood 2004; 104: 2867-2872.
    • (2004) Blood , vol.104 , pp. 2867-2872
    • Clark, J.J.1    Cools, J.2    Curley, D.P.3    Yu, J.C.4    Lokker, N.A.5    Giese, N.A.6
  • 8
    • 85044557188 scopus 로고    scopus 로고
    • Comparison of nilotinib and imatinib inhibition of FMS receptor signaling, macrophage production and osteoclastogenesis
    • e-pub ahead of print 13 September
    • Brownlow N, Russell AE, Saravanapavan H, Wiesmann M, Murray JM, Manley PW et al. Comparison of nilotinib and imatinib inhibition of FMS receptor signaling, macrophage production and osteoclastogenesis. Leukemia 2007; e-pub ahead of print 13 September 2007.
    • (2007) Leukemia 2007
    • Brownlow, N.1    Russell, A.E.2    Saravanapavan, H.3    Wiesmann, M.4    Murray, J.M.5    Manley, P.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.