-
2
-
-
0033758958
-
FLT3 internal tandem duplication mutations in adult myeloid leukaemia define a high risk group
-
(2000)
British Journal of Haematology
, vol.111
, pp. 190-195
-
-
Abu-Duhier, F.M.1
Goodeve, A.C.2
Wilson, G.A.3
Gari, M.A.4
Peake, I.R.5
Rees, D.C.6
Vandenberghe, E.A.7
Winship, P.R.8
Reilly, J.T.9
-
10
-
-
0028046436
-
Translocation t(5;12) (q31-q33;p12-p13): A non-random translocation associated with a myeloid disorder with eosinophilia
-
(1994)
British Journal of Haematology
, vol.88
, pp. 343-347
-
-
Baranger, L.1
Szapiro, N.2
Gardais, J.3
Hillion, J.4
Derre, J.5
Francois, S.6
Blanchet, O.7
Boasson, M.8
Berger, R.9
-
14
-
-
0022626874
-
A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family
-
(1986)
Nature
, vol.320
, pp. 415-421
-
-
Besmer, P.1
Murphy, J.E.2
George, P.C.3
Qui, F.4
Bergold, P.J.5
Ledermann, L.6
Synder, H.W.7
Brodeur, D.8
Zuckermann, E.E.9
Hardy, W.D.10
-
15
-
-
0026457216
-
Expression of the FMS/KIT-like gene FLT3 in human acute leukemias of the myeloid and lymphoid lineages
-
(1992)
Blood
, vol.80
, pp. 2584-2593
-
-
Birg, E.1
Courcoul, M.2
Rosnet, O.3
Bardin, F.4
Pebusque, M.-J.5
Marchetto, S.6
Tabilio, A.7
Mannoni, P.8
Birnbaum, D.9
-
20
-
-
0031454003
-
CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL. TEL-ABL, and TEL-PDGFb fusion proteins
-
(1997)
Blood
, vol.90
, pp. 4947-4952
-
-
Carroll, M.1
Ohno-Jones, S.2
Tamura, S.3
Buchdunger, E.4
Zimmer-Mann, J.5
Lydon, N.B.6
Gilliland, D.G.7
Druker, B.J.8
-
21
-
-
0032878921
-
The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia
-
(1999)
Nature Genetics
, vol.23
, pp. 144-146
-
-
Castilla, L.H.1
Garrett, L.2
Adya, N.3
Orlic, D.4
Dutra, A.5
Anderson, S.6
Owens, J.7
Eckhaus, M.8
Bodline, D.9
Liu, P.P.10
-
25
-
-
0022542014
-
Structural alteration of viral homologue of receptor proto-oncogene fms at C terminus
-
(1986)
Nature
, vol.320
, pp. 277-280
-
-
Coussens, L.1
Van Beveren, C.2
Smith, D.3
Chen, E.4
Mitchell, R.L.5
Isacke, C.M.6
Verma, I.M.7
Ullrich, A.8
-
28
-
-
0030002950
-
Expression of FLT3 receptor and response of to FLT3 ligand by leukemic cells
-
(1996)
Leukemia
, vol.10
, pp. 588-599
-
-
Drexler, H.G.1
-
29
-
-
0000796896
-
Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells
-
(2000)
British Journal of Haematology
, vol.108
, pp. 322-330
-
-
Fenski, R.1
Flesch, K.2
Serve, S.3
Mizuki, M.4
Oelmann, E.5
Kratz-Albers, K.6
Kienast, J.7
Leo, R.8
Schwartz, S.9
Berdel, W.E.10
Serve, H.11
-
31
-
-
85112393651
-
Incidence and prognostic significance of internal tandem duplications of the FLT3 gene in AML, with normal cytogenetics: Analysis of 84 patients treated within the multicenter trial AML HD93
-
(2000)
Blood
, vol.96
-
-
Fröhling, S.1
Schlenk, R.E.2
Döhner, H.3
Döhner, K.4
-
32
-
-
0028871554
-
Expression of the c-kit gene product in normal and neoplastic mast cells but not in neoplastic basophil/mast cell precursors from chronic myeloid leukemia
-
(1995)
Journal of Pathology
, vol.177
, pp. 139-146
-
-
Fukuda, T.1
Kamishima, T.2
Tsuura, Y.3
Suzuki, T.4
Kakihara, T.5
Naito, M.6
Kishi, K.7
Matsumoto, K.8
Shibata, A.9
Seito, T.10
-
33
-
-
0027359443
-
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product
-
(1993)
Journal of Clinical Investigation
, vol.92
, pp. 1736-1744
-
-
Furitsu, T.1
Tsujimura, T.2
Tono, T.3
Ikeda, H.4
Kitayama, H.5
Koshimizu, U.6
Sugahara, H.7
Butterfield, J.H.8
Ashman, L.K.9
Kanayama, Y.10
Matsuzawa, Y.11
Kitamura, Y.12
Kanakura, Y.13
-
34
-
-
0032989226
-
c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukaemia
-
(1999)
British Journal of Haematology
, vol.105
, pp. 894-900
-
-
Gari, M.1
Goodeve, A.2
Wilson, G.3
Winship, P.4
Langabeer, S.5
Linch, D.6
Vandenberghe, E.7
Peake, I.8
Reilly, J.9
-
37
-
-
0023190792
-
Frequent c-fms activation by proviral insertion in mouse myeloblastic leukaemias
-
(1987)
Nature
, vol.329
, pp. 259-261
-
-
Gisselbrecht, S.1
Fichelson, S.2
Sola, B.3
Bordereaux, D.4
Hampe, A.5
Andre, C.6
Galibert, F.7
Tambourin, P.8
-
42
-
-
4244188890
-
Point mutations in the FLT3 gene in AML
-
(2001)
Blood
, vol.97
, pp. 2193
-
-
Griffin, J.D.1
-
49
-
-
15644363454
-
Gain-of-function mutations of human gastrointestinal stromal tumors
-
(1998)
Science
, vol.279
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
Hasimoto, K.4
Nishida, T.5
Ishigura, S.6
Kawano, K.7
Hanada, M.8
Kurata, A.9
Takeda, M.10
Muhammad, T.G.11
Matsuzawa, Y.12
Kanakura, Y.13
Shinomura, Y.14
Kitamura, Y.15
-
50
-
-
0034194325
-
Specific c-kit mutations in sinonasal natural killer/T-cell lymphoma in China and Japan
-
(2000)
Cancer Research
, vol.60
, pp. 2345-2347
-
-
Hongyo, T.1
Li, T.2
Syaifudin, M.3
Baskar, R.4
Ikeda, H.5
Kanakura, Y.6
Aozasa, K.7
Nomura, T.8
-
51
-
-
16944366584
-
Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia
-
(1997)
Leukemia
, vol.11
, pp. 1442-1446
-
-
Horiike, S.1
Yokota, S.2
Nakao, M.3
Iwai, T.4
Sasai, Y.5
Kaneko, H.6
Taniwaki, M.7
Kashima, K.8
Fujii, H.9
Abe, T.10
Misawa, S.11
-
52
-
-
0025718579
-
Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells
-
(1991)
Blood
, vol.78
, pp. 2962-2968
-
-
Ikeda, H.1
Kanakura, Y.2
Tamaki, T.3
Kuriu, A.4
Kitayama, H.5
Ishikawa, J.6
Kanayama, Y.7
Yonzawa, T.8
Tarui, S.9
Griffin, J.10
-
54
-
-
0027367406
-
Expression of platelet-derived growth factor b receptor on human monocyte-derived macrophages and effects of platelet-derived growth factor BB dimer on the cellular function
-
(1993)
Journal of Biological Chemistry
, vol.268
, pp. 24353-24360
-
-
Inaba, T.1
Shimano, H.2
Gotoda, T.3
Harada, K.4
Shimada, M.5
Ohsuga, J.6
Watanabe, Y.7
Kawamura, M.8
Yazaki, Y.9
Yamada, N.10
-
55
-
-
0032401747
-
A single amino acid substitution in a WW-like domain of diverse members of the PDGF receptor subfamily of tyrosine kinases causes constitutive receptor activation
-
(1998)
EMBO Journal
, vol.17
, pp. 6912-6923
-
-
Irusta, P.M.1
DiMaio, D.2
-
57
-
-
0032931560
-
Internal tandem duplication of the FLT3 gene and clincal evaluation in childhood acute myeloid leukemia
-
(1999)
Leukemia
, vol.13
, pp. 38-43
-
-
Iwai, T.1
Yokota, S.2
Nakao, M.3
Okamoto, T.4
Taniwaki, M.5
Onodera, N.6
Watanabe, A.7
Kikuta, A.8
Tanaka, A.9
Asami, K.10
Sekine, I.11
Mugishima, H.12
Nishimura, Y.13
Koizumi, S.14
Horikoshi, Y.15
Mimaya, J.16
Ohta, S.17
Nishikawa, K.18
Iwai, A.19
Shimokawa, T.20
Nakayama, M.21
Kawakami, K.22
Gushiken, T.23
Hyakuna, N.24
Katano, N.25
Tsurusawa, M.26
Fujimoto, T.27
more..
-
59
-
-
17144463437
-
A domain of TEL conserved in a subset of ETS proteins defines a specific oligo-merization interface essential to the mitogenic properties of the TEL-PDGFR oncoprotein
-
(1997)
EMBO Journal
, vol.16
, pp. 69-82
-
-
Jousset, C.1
Carron, C.2
Oury, C.3
Susanter-Fourt, I.4
Charon, M.5
Levin, J.6
Bernard, O.7
Ghysdael, J.8
-
60
-
-
0030986659
-
HIP1, a human homologue of S. cerevisiae SIa2p, interacts with membrane-associated huntingtin in the brain
-
(1997)
Nature Genetics
, vol.16
, pp. 44-53
-
-
Kalchman, M.A.1
Koide, H.B.2
McCutcheon, K.3
Graham, R.K.4
Nichol, K.5
Nishiyama, K.6
Kazemi-Esfarjani, P.7
Lynn, F.C.8
Wellington, C.9
Metzler, M.10
Goldberg, Y.P.11
Kanazawa, I.12
Gietz, R.D.13
Hayden, M.R.14
-
61
-
-
0035312964
-
Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF β-receptor null mice
-
(2001)
Blood
, vol.97
, pp. 1990-1998
-
-
Kaminski, W.E.1
Lindahl, P.2
Lin, N.L.3
Broudy, V.C.4
Crosby, J.R.5
Hellström, M.6
Swolin, B.7
Bowen-Pope, D.F.8
Martin, P.J.9
Ross, R.10
Betsholtz, C.11
Raines, E.W.12
-
64
-
-
0023215263
-
Abnormalities of chromosome 12p13 and malignant proliferation of eosinophils: A non-randomassociation
-
(1987)
British Journal of Haematology
, vol.67
, pp. 25-31
-
-
Keene, P.1
Mendelow, B.2
Pinto, M.R.3
Bezwoda, W.4
MacDougall, L.5
Falkson, G.6
Ruff, P.7
Bernstein, R.8
-
67
-
-
0028959163
-
Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines
-
(1995)
Blood
, vol.85
, pp. 790-798
-
-
Kitayama, H.1
Kanakura, Y.2
Furitsu, T.3
Tsujimura, T.4
Oritani, K.5
Ikeda, H.6
Sugahara, H.7
Mitsui, H.8
Kanayama, Y.9
Kitamura, Y.10
Matsuzawa, Y.11
-
68
-
-
0033134792
-
Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia
-
(1999)
Blood
, vol.93
, pp. 3074-3080
-
-
Kiyoi, H.1
Naoe, T.2
Nakano, Y.3
Yokota, S.4
Minami, S.5
Miyawaki, S.6
Asou, N.7
Kuriyama, K.8
Jinnai, I.9
Shimazaki, C.10
Akiyama, H.11
Saito, K.12
Oh, H.13
Motoji, T.14
Omoto, E.15
Saito, H.16
Ohno, R.17
Ueda, R.18
-
69
-
-
16944362760
-
Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia
-
(1997)
Leukemia
, vol.11
, pp. 1447-1452
-
-
Kiyoi, H.1
Naoe, T.2
Yokota, S.3
Nakao, M.4
Minami, S.5
Kuriyama, K.6
Takeshita, A.7
Saito, K.8
Hasegawa, S.9
Shimodaira, S.10
Tamura, J.11
Shimazaki, C.12
Matsue, K.13
Kobayashi, H.14
Arima, N.15
Suzuki, R.16
Morishita, H.17
Saito, H.18
Ueda, R.19
Ohno, R.20
more..
-
71
-
-
0032757551
-
Prognostic value of internal tandem duplication of the FLT3 gene in childhood acute myeloid leukaemia
-
(1999)
Medical Pediatric Oncology
, vol.33
, pp. 525-529
-
-
Kondo, M.1
Horibe, K.2
Takahashi, Y.3
Matsumoto, K.4
Fukuda, M.5
Inaba, J.6
Kojima, S.7
Matsuyama, T.8
-
72
-
-
0009486012
-
The presence of a FLT3 mutation in AML adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the MRC AML 10 and 12 trials
-
(2000)
Blood
, vol.96
-
-
Kottaridis, P.D.1
Gale, R.E.2
Frew, M.E.3
Harrison, G.4
Langabeer, S.E.5
Belton, A.A.6
Walker, H.7
Wheatley, K.8
Bowen, D.T.9
Burnett, A.K.10
Goldstone, A.H.11
Linch, D.C.12
-
73
-
-
18344404198
-
Fusion of H4/D10S170 to the platelet-derived growth factor receptor β in bcr-abl negative myeloproliferative disorders with a t (5; 10) (q33;q21)
-
(2000)
Cancer Research
, vol.60
, pp. 3592-3598
-
-
Kulkarni, S.1
Heath, C.2
Parker, S.3
Chase, A.4
Iqbal, S.5
Pocock, C.F.6
Kaeda, J.7
Cwynarski, K.8
Goldman, J.M.9
Cross, N.C.P.10
-
76
-
-
13044305857
-
Activating and dominant inactivating c-kit catalytic domain mutations in distinct clinical forms of human mastocytosis
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 1609-1614
-
-
Longley, B.J.1
Metcalfe, D.D.2
Tharp, M.3
Wang, X.4
Tyrrell, L.5
Lu, S.Z.6
Heitjan, D.7
Ma, Y.8
-
78
-
-
0032519768
-
c-kit ligand and Flt3 ligand: Stem/progenitor cell factors with overlapping yet distinct activities
-
(1998)
Blood
, vol.91
, pp. 1101-1134
-
-
Lyman, S.D.1
Jacobsen, S.E.W.2
-
85
-
-
0029145627
-
Expression of FLT3 receptor and FLT-3 ligand in human leukemia-lymphoma cell lines
-
(1995)
Leukemia
, vol.9
, pp. 1368-1372
-
-
Meierhoff, G.1
Dehmel, U.2
Gruss, H.-J.3
Rosnet, O.4
Birnhaum, D.5
Quentmeier, H.6
Dirks, W.7
Drexler, H.G.8
-
86
-
-
0035168677
-
Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia
-
(2001)
Blood
, vol.97
, pp. 89-94
-
-
Meshinchi, S.1
Woods, W.G.2
Stirewalt, D.L.3
Sweetser, D.A.4
Buckley, J.D.5
Tjoa, T.K.6
Berstein, I.D.7
Radich, J.P.8
-
88
-
-
4243283370
-
Multiple signalling pathways mediate leukemogenic activity of internal tandem duplication mutations of FLT3 in AML
-
(2000)
Blood
, vol.96
-
-
Mizuki, M.1
Steur, C.2
Halfter, H.3
Matsumura, I.4
Schmidt, R.5
Mueller, C.6
Gruening, W.7
Kratz-Albers, K.8
Schwaeble, J.9
Buechner, T.10
Kienast, J.11
Kanakura, Y.12
Berdel, W.E.13
Serve, H.14
-
89
-
-
0034554796
-
Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways
-
(2000)
Blood
, vol.96
, pp. 3907-3914
-
-
Mizuki, M.1
Fenski, R.2
Halfter, H.3
Matsumura, I.4
Schmidt, R.5
Müller, C.6
Grüning, W.7
Kratz-Albers, K.8
Serve, S.9
Steur, C.10
Büchner, T.11
Kienast, J.12
Kanakura, Y.13
Berdel, W.E.14
Serve, H.15
-
94
-
-
0030451722
-
Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
-
(1996)
Leukemia
, vol.10
, pp. 1911-1918
-
-
Nakao, M.1
Yokota, S.2
Iwai, T.3
Kaneko, H.4
Horiike, S.5
Kashima, K.6
Sonoda, Y.7
Fujimoto, T.8
Misawa, S.9
-
96
-
-
0028849992
-
c-kit point mutation of extracellular domain in patients with myeloproliferative disorders
-
(1995)
British Journal of Haematology
, vol.91
, pp. 661-663
-
-
Nakata, Y.1
Kimura, A.2
Katoh, O.3
Kawaishi, K.4
Hyodo, H.5
Abe, K.6
Kuramoto, A.7
Satow, Y.8
-
97
-
-
0035383812
-
Signal transducer and activator of transcription 3 activation is required for Asp816 mutant c-kit-mediated cytokine-independent survival and proliferation in human leukemia cells
-
(2001)
Blood
, vol.97
, pp. 3559-3567
-
-
Ning, Z.-Q.1
Li, J.2
Arceci, R.J.3
-
100
-
-
0029888193
-
Myelodysplastic syndrome with t (5; 12) (q31; p12-p13) and eosinophilia: A pediatric case with review of literature
-
(1996)
Journal of Pediatric Hematology Oncology
, vol.18
, pp. 285-288
-
-
Pellier, I.1
Le Moine, P.J.2
Rialland, X.3
François, S.4
Baranger, L.5
Blanchet, O.6
Larget-Piet, L.7
Ifrah, N.8
-
102
-
-
0031039992
-
A new c-kit mutation in a case of aggressive mast cell disease
-
(1997)
British Journal of Haematology
, vol.96
, pp. 374-376
-
-
Pignon, J.-M.1
Giraudier, S.2
Duquesnoy, P.3
Jouault, H.4
Imbert, M.5
Vainchenker, W.6
Vernant, J.-P.7
Tulliez, M.8
-
107
-
-
0032589693
-
The Tel PDGFRb fusion gene produces a chronic myelo-proliferative syndrome in transgenic mice
-
(1999)
Leukemia
, vol.13
, pp. 1790-1803
-
-
Ritchie, K.A.1
Aprikyan, A.A.G.2
Bowen-Pope, D.F.3
Norby-Slycord, C.I.4
Conyers, S.5
Sitnicka, E.6
Bartelmez, S.H.7
Hickstein, D.D.8
-
113
-
-
0027301288
-
Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells
-
(1993)
Blood
, vol.82
, pp. 1110-1119
-
-
Rosnet, O.1
Schiff, C.2
Pébusque, M.-J.3
Marchetto, S.4
Tonnelle, C.5
Toiron, Y.6
Birg, F.7
Birnbaum, D.8
-
115
-
-
9044233643
-
Expression and signal transduction of the FLT3 tyrosine kinase receptor
-
(1996)
Acta Haematologica
, vol.95
, pp. 218-223
-
-
Rosnet, O.1
Buhring, H.J.2
De Lapevriere, O.3
Beslu, N.4
Lavagna, C.5
Marchetto, S.6
Rappold, I.7
Drexler, H.G.8
Birg, F.9
Rottapel, R.10
Hannum, C.11
Dubreuil, P.12
Birnbaum, D.13
-
121
-
-
0035877975
-
H4 (D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor b gene in atypical chronic myeloid leukemia with t (5; 10) (q33;q22)
-
(2001)
Blood
, vol.97
, pp. 3910-3918
-
-
Schwaller, J.1
Anastasiadou, E.2
Cain, D.3
Kutok, J.4
Wojiski, S.5
Williams, I.R.6
LaStarza, R.7
Crescenzi, B.8
Sternberg, D.W.9
Andreasson, P.10
Schiavo, R.11
Sienna, S.12
Mecucci, C.13
Gilliland, D.C.14
-
123
-
-
0025058345
-
Colony-stimulating factor-1 receptor
-
(1990)
Blood
, vol.75
, pp. 1-12
-
-
Sherr, C.J.1
-
125
-
-
0032853078
-
New reciprocal translocation t (5; 10) (q33;q22) associated with atypical chronic myeloid leukaemia
-
(1999)
Haematologica
, vol.84
, pp. 369-372
-
-
Siena, S.1
Sammarelli, G.2
Grimoldi, M.G.3
Schiavo, R.4
Nozza, A.5
Roncalli, M.6
Mecucci, C.7
Santoro, A.8
Carlo-Stella, C.9
-
128
-
-
0033867827
-
Detection of c-kit mutation Asp816 to Val in microdissected bone marrow infil-trates in a case of systemic mastocytosis associated with chronic myelomonocytic leukaemia
-
(2000)
Journal of Clinical Pathology: Molecular Pathology
, vol.53
, pp. 188-193
-
-
Sotlar, K.1
Marafioti, T.2
Griesser, H.3
Theil, J.4
Aepinus, C.5
Jaussi, R.6
Stein, H.7
Valent, P.8
Horny, H.-P.9
-
129
-
-
7844228063
-
Systemic mastocytosis associated with acute myeloid leukemia: Report of two cases and detection of the c-kit mutation Asp816 to Val
-
(1998)
British Journal of Haematology
, vol.103
, pp. 704-749
-
-
Sperr, W.R.1
Walchshofer, S.2
Horny, H.P.3
Fodinger, M.4
Simonitsch, I.5
Fritsche-Polanz, R.6
Schwarzinger, I.7
Tschachler, E.8
Sillaber, C.9
Hagen, W.10
Geissler, K.11
Chott, A.12
Lechner, K.13
Valent, P.14
-
131
-
-
0023804346
-
KRAS oncogene overexpression in myelodysplastic syndrome with translocation 5: 12
-
(1988)
Cancer Genetics Cytogenetics
, vol.35
, pp. 61-71
-
-
Srivastava, A.1
Boswell, H.S.2
Heerema, N.A.3
Nahreini, P.4
Lauer, R.C.5
Antony, A.C.6
Hoffman, R.7
Tricot, G.J.8
-
133
-
-
2042464859
-
Identification of novel translocations that disrupt the platelet-derived growth factor receptor beta (PDGFBR) gene in BCR-ABL negative chronic myeloproliferative disorders
-
(2001)
The Hematology Journal
, vol.1
, pp. 16
-
-
Steer, E.J.1
Kulkarni, S.2
Vizmanos, J.L.3
Testoni, N.4
Martinelli, G.5
Russell-Jones, R.6
Stark, A.7
Giraldo, P.8
Stewart, J.9
Pocock, C.10
Goldman, J.M.11
Cross, N.C.P.12
-
134
-
-
0035383768
-
FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukaemia
-
(2001)
Blood
, vol.97
, pp. 3589-3595
-
-
Stirewalt, D.L.1
Kopecky, K.J.2
Meshinchi, S.3
Appelbaum, F.R.4
Slovak, M.L.5
Willman, C.L.6
Radich, J.P.7
-
138
-
-
0033084227
-
TEL/PDGFβR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor
-
(1999)
Blood
, vol.93
, pp. 1707-1714
-
-
Tomasson, M.H.1
Williams, I.R.2
Hasserjian, R.3
Udomsakdi, C.4
McGrath, S.M.5
Schwaller, J.6
Druker, B.7
Gilliland, D.G.8
-
139
-
-
0033999917
-
Fatal myeloproliferation, induced in mice by TEL/PDGFbR expression, depends on PDGFbR tyrosines 579/581
-
(2000)
Journal of Clinical Investigation
, vol.105
, pp. 423-432
-
-
Tomasson, M.H.1
Sternberg, D.W.2
Wiulliams, I.R.3
Carroll, M.4
Cain, D.5
Aster, J.C.6
Ilaria, R.L.7
Van Etten, R.A.8
Gilliland, D.G.9
-
140
-
-
15844406351
-
Functional receptor for GDNF encoded by the c-ret proto-oncogene
-
(1996)
Nature
, vol.381
, pp. 785-789
-
-
Trupp, M.1
Arenas, E.2
Fainzilber, M.3
Nilsson, A.S.4
Sieber, B.A.5
Grigoriou, M.6
Kilkenny, C.7
Salazar-Gruesco, E.8
Pachnis, V.9
Arumae, U.10
-
142
-
-
0025912874
-
Induction of mast cell proliferation, maturation, and heparin synthesis by the rat c-kit ligand, stem cell factor
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, pp. 6382-6386
-
-
Tsai, M.1
Takeishi, T.2
Thompson, H.3
Langley, K.E.4
Zsebo, K.M.5
Metcalfe, D.D.6
Geissler, E.N.7
Galli, S.J.8
-
144
-
-
0028229976
-
Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation
-
(1994)
Blood
, vol.83
, pp. 2619-2626
-
-
Tsujimura, T.1
Furitsu, T.2
Morimoto, M.3
Isozaki, K.4
Nomura, S.5
Matsuzawa, Y.6
Kitamura, Y.7
Kanakura, Y.8
-
145
-
-
0028968751
-
Substitution of an aspartic acid results in constitutive activation of c-kit receptor tyrosine kinase in a rat tumor mast cell line RBL-2H3
-
(1995)
International Archives of Allergy and Immunology
, vol.106
, pp. 377-385
-
-
Tsujimura, T.1
Furitsu, T.2
Morimoto, M.3
Kanayama, Y.4
Nomura, S.5
Matsuzawa, Y.6
Kitamura, Y.7
Kanakura, Y.8
-
146
-
-
0030032943
-
Constitutive activation of c-kit in FMA3 murine masto-cytoma cells caused by deletion of seven amino acids at the juxtamembrane domain
-
(1996)
Blood
, vol.87
, pp. 271-283
-
-
Tsujimura, T.1
Morimoto, M.2
Hashimoto, K.3
Moriyama, Y.4
Kitayama, H.5
Matsuzawa, Y.6
Kitamura, Y.7
Kanakura, Y.8
-
147
-
-
0033557589
-
Activating mutation in the catalytic domain of c-kit elicits hematopoietic transformation by receptor self association not at the ligand-induced dimerization site
-
(1999)
Blood
, vol.93
, pp. 1319-1329
-
-
Tsujimura, T.1
Hashimoto, K.2
Kitayama, H.3
Ikeda, H.4
Sugahara, H.5
Matsumura, I.6
Kaisho, T.7
Terada, N.8
Kitamura, Y.9
Kanakura, Y.10
-
151
-
-
0020640259
-
Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus
-
(1983)
Nature
, vol.304
, pp. 35-39
-
-
Waterfield, M.D.1
Scrace, G.T.2
Whittle, N.3
Stroobant, P.4
Johnsson, A.5
Wasteson, A.6
Westermark, B.7
Heldin, C.H.8
Huang, J.S.9
Deuel, T.F.10
-
153
-
-
0027478524
-
T (5; 12) (q31;p12): A clinical entity with features of both myeloid leukemia and chronic myelomonocytic leukemia
-
(1993)
Cancer Genetics Cytogenetics
, vol.65
, pp. 7-11
-
-
Wessels, J.W.1
Fibbe, W.E.2
Van der Keur, D.3
Landegent, J.E.4
Van der Plas, D.C.5
Den Ottolander, G.J.6
Roozendaal, K.J.7
Beverstock, G.C.8
-
157
-
-
0001097136
-
Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children
-
(1999)
British Journal of Haematology
, vol.105
, pp. 155-162
-
-
Xu, F.1
Yang, H.W.2
Hanada, R.3
Hongo, T.4
Ohnishi, H.5
Kobayashi, M.6
Bessho, F.7
Yanagisawa, M.8
Hayashi, Y.9
-
158
-
-
0035871889
-
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
-
(2001)
Blood
, vol.97
, pp. 2434-2439
-
-
Yamamoto, Y.1
Kiyoi, H.2
Nakano, Y.3
Suzuki, R.4
Kodera, Y.5
Miyawaki, S.6
Asou, N.7
Kuriyama, K.8
Yagasaki, F.9
Shimazaki, C.10
Akiyama, H.11
Saito, K.12
Nishimura, M.13
Motoji, T.14
Shinagawa, K.15
Takeshita, A.16
Saito, H.17
Ueda, R.18
Ohno, R.19
Naoe, T.20
more..
-
161
-
-
0022541219
-
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors
-
(1986)
Nature
, vol.323
, pp. 226-232
-
-
Yarden, Y.1
Escobedo, J.A.2
Kuang, W.-J.3
Yang-Feng, T.L.4
Daniel, T.O.5
Tremble, P.M.6
Chen, E.Y.7
Ando, M.E.8
Harkins, R.N.9
Francke, U.10
Fried, V.A.11
Ullrich, A.12
Williams, L.T.13
-
162
-
-
2742529418
-
Human proto-oncogene c-kit: A new cell surface receptor tyrosine kinase for an unidentified ligand
-
(1987)
EMBO Journal
, vol.6
, pp. 3341-3351
-
-
Yarden, Y.1
Kuang, W.J.2
Yang-Feng, T.3
Coussens, L.4
Munemitsu, S.5
Dull, T.J.6
Chen, E.7
Schlessinger, J.8
Francke, U.9
Ullrich, A.10
-
163
-
-
16944365287
-
Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines
-
(1997)
Leukemia
, vol.11
, pp. 1605-1609
-
-
Yokota, S.1
Kiyoi, H.2
Nakao, M.3
Iwai, T.4
Misawa, S.5
Okuda, T.6
Sonoda, Y.7
Abe, T.8
Kahsima, K.9
Matsuo, Y.10
Naoe, T.11
-
164
-
-
0034093724
-
In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor
-
(2000)
Leukemia
, vol.14
, pp. 374-378
-
-
Zhao, M.1
Kiyoi, H.2
Yamamoto, Y.3
Ito, M.4
Towatari, M.5
Omura, W.S.6
Kitamura, T.7
Ueda, R.8
Saito, H.9
Naoe, T.10
|