Antitumor effects of Isatin on human neuroblastoma cell line (SH-SY5Y) and the related mechanism

European Journal of Pharmacology

Volumn 589, Issue 1-3, 2008, Pages 27-31

  Hou, Lin ^a   Ju, Chuanxia ^a   Zhang, Jinyu ^a   Song, Jinlian ^b   Ge, Yinlin ^a   Yue, Wang ^a  

^a QINGDAO UNIVERSITY   (China)

^b Women and Children's Health and Care Center of Qingdao City   (China)

Author keywords

Apoptosis; Bax; Bcl 2; Caspase 3; Human neuroblastoma cell; Isatin; Mechanism; Vascular endothelial growth factor

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CASPASE 3; ISATIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN BCL 2; VASCULOTROPIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZIMIDAZOLES; BLOTTING, WESTERN; CASPASE 3; CELL LINE, TUMOR; COLORING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; HUMANS; ISATIN; NEUROBLASTOMA; PHOSPHORYLATION; PROPIDIUM; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STAINING AND LABELING; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 47549085531     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.04.061     Document Type: Article

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