Effects of tobacco compounds on gene expression in fetal lung fibroblasts

Environmental Toxicology

Volumn 23, Issue 4, 2008, Pages 423-434

  Sohn, Sung Hwa ^a   Kim, Ki Nam ^a   In, Kyoung Kim ^a   Lee, Eun Il ^a   Ryu, Jae Jun ^a   Kim, Meyoung Kon ^a  

^a Korea University College of Medicine   (South Korea)

Author keywords

2 Naphthylamine; B(a)P; cDNA microarray; Gene expression profile; Nicotine; Tobacco compounds

Indexed keywords

AGRICULTURAL PRODUCTS; AMINO ACIDS; ARSENIC COMPOUNDS; BIOACTIVITY; BIOLOGICAL ORGANS; BOTTLES; FIBROBLASTS; GENE EXPRESSION; TISSUE CULTURE; TOBACCO;

BENZO(A)PYRENE; CDNA MICROARRAY; CELL LINES; FETAL BOVINE SERUM (FBS); GENE EXPRESSION PROFILING; L GLUTAMINE; NAPHTHYLAMINE; PENICILLIN (PE); REAL-TIME PCR;

CELL CULTURE;

2 NAPHTHYLAMINE; BENZO[A]PYRENE; COMPLEMENTARY DNA; GLUTAMINE; NICOTINE; PENICILLIN G; STREPTOMYCIN;

CYTOLOGY; EMBRYO; GENE EXPRESSION; PHYSIOLOGICAL RESPONSE; REAL TIME; TOBACCO;

APOPTOSIS; ARNT GENE; ARTICLE; BAD GENE; CELL CULTURE; CELL GROWTH; CELL LINE; CONTROLLED STUDY; CULTURE MEDIUM; DFFB GENE; DNA MICROARRAY; DNASE2 GENE; DOWN REGULATION; EQUIPMENT; FETUS; GENE; GENE EXPRESSION PROFILING; GENOME; HUMAN; HUMAN CELL; IMMUNITY; LUNG FIBROBLAST; MADD GENE; MST1 GENE; NME3 GENE; PRIORITY JOURNAL; RARG GENE; REAL TIME POLYMERASE CHAIN REACTION; SERUM; TISSUE CULTURE FLASK; TNFRSF1A GENE; TOBACCO;

2-NAPHTHYLAMINE; BENZO(A)PYRENE; CELL LINE; CELL SURVIVAL; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; LUNG; NICOTINE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOBACCO;

BOVINAE; NICOTIANA TABACUM;

EID: 47549085175     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20335     Document Type: Article

References (36)

1. Angus WGR, Larsen MC, Jefcoate CR. 1999. Expression of CYP1A1 and CYP1B1 depends on cell-specific factors in human breast cancer cell lines: role of estrogen receptor status. Carcinogenesis 20:947-955.
2. Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. 2006. Receptor-mediated tobacco toxicity: Cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of a7 nicotinic receptor in oral keratinocytes. FASEB J 20:2093-2101.
3. Brierley MM, Fish EN. 2005. Stats: Multifaceted regulators of transcription. J Interferon Cytokine Res 25:733-744.
4. Dertinger SD, Nazarenko DA, Silverstone AE, Gasiewicz TA. 2001. Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigarette smoke condensate-induced cytogenetic damage in vivo. Carcinogenesis 22:171-177.
5. Dohr O, Sinning R, Vogel C, Munzel P, Abel J. 1997. Effect of transforming growth factor-β1 on expression of aryl hydrocarcone receptor and genes of Ah gene battery: Clues for independent down-regulation in A549 cells. Mol Pharmacol 51: 703-710.
6. Duursen MBM, Sanderson JT, Berg M. 2005. Cytochrome P450 1A1 and 1B1 in human blood lymphocytes are not suitable as biomarkers of exposure to dioxin-like compounds: Polymorphism and interindividual variation in expression and inducibility. Toxicol Sci 85:703-712.
7. Eisen MB, Spellman PT, Brown PO, Botstein D. 1998. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 95:14863-14868.
8. Ellenrieder V, Buck A, Harm A, Jungert K, Buchholz M, Adler G, Urrutia R, Gress TM. 2004. KLF11 mediates a critical mechanism in TGF-β signaling that is inactivated by ERK-MAPK in pancreatic cancer cells. Gastroenterology 127:607-620.
9. Eltom SE, Zhang L, Jefcoate CR. 1999. Regulation of Cytochrome P-450 (CYP) 1B1 in mouse Hepa-1 variant cell lines: A possible role for aryl hydrocarbon receptor nuclear translocator (arnt) as a suppressor of CYP1B1 gene expression. Mol Pharmacol 55:594-604.
10. Fowles J, Dybing E. 2003. Application of toxicological risk assessment principles to the chemical constituents of cigarette smoke. Tob Control 12:424-430.
11. Gebremichael A, Tullis K, Denison MS, Cheek JM, Pinkerton KE. 1996. Ah-receptor-dependent modulation of gene expression by aged and diluted sidestream cigarette smoke. Toxicol Appl Pharmacol 141:76-83.
12. Hainaut P, Pfeifer GP. 2001. Patterns of p53 G - >T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke. Carcinogenesis 22:367-374.
13. Honma N, Asada A, Takeshita S, Enomoto M, Yamakawa E, Tsutsumi K, Saito T, Satoh T, Itoh H, Kaziro Y, Kishimoto T, Hisanaga S. 2003. Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein. Biochem Biophys Res Commun 310:398-404.
14. Husbeck B, Powis G. 2002. The redox protein thioredoxin-1 regulates the constitutive and inducible expression of the estrogen metabolizing cytochromes P450 1B1 and 1A1 in MCF-7 human breast cancer cells. Carcinogenesis 23:1625-1630.
15. Jin Z, Gao F, Flagg T, Deng X. 2004. Nicotine induces multi-site phosphorylation of Bad in association with suppression of apoptosis. J Biol Chem 28:23837-23844.
16. Karp JM, Rodrigo KA, Pei P, Pavlick MD, Andersen JD, Mc Tigue DJ, Fields HW, Mallery SR. 2005. Sanguinarine activates polycyclic aromatic hydrocarbon associated metabolic pathways in human oral keratinocytes and tissues. Toxicol Lett 158:50-60.
17. Kellen E, Zeegers M, Paulussen A, Vlietinck R, Vlem EV, Veulemans H, Buntinx F. 2006. Does occupational exposure to PAHs, diesel and aromatic amines interact with smoking and metabolic genetic polymorphisms to increase the risk on bladder cancer? The Belgian case control study on bladder cancer risk. Cancer Lett 245:51-60.
18. Larsen MC, Brake PB, Pollenz RS, Jefcoate CR. 2004. Linked expression of Ah receptor, ARNT, CYP1A1, and CYP1B1 in rat mammary epithelia, in vitro, is each substantially elevated by specific extracellular matrix interactions that precede branching morphogenesis. Toxicol Sci 82:46-61.
19. Lin P, Hu SW, Chang TH. 2003. Correlation between gene expression of aryl hydrocarbon receptor (AhR), hydrocarbone receptor nuclear translocator (Arnt), cytochromes P4501A1 (CYP1A1) and 1B1 (CYP1B1), and inducibilty of CYP1A1 and CYP1B1 in human lymphocytes. Toxicol Sci 71:20-26.
20. Lin P, Chang JT, Ko JL, Liao SH, Lo WS. 2004. Reduction of androgen receptor expression by benzo[a]pyrene and 7,8-dihydro-9,10-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene in human lung cells. Biochem Pharmacol 67:1523-1530.
21. Luan X, Diekwisch TGH. 2002. CP27 affects viability, proliferation, attachment and gene expression in embryonic fibroblasts. Cell Prolif 35:207-219.
22. Mayne M, Cheadle C, Soldan SS, Cermelli C, Yamano Y, Akhyani N, Nagel JE, Taub DD, Becker KG, Jacobson S. 2001. Gene expression profile of herpesvirus-infected T cells obtained using immunomicroarrays: induction of proinflammatory mechanisms. J Virol 75:11641-11650.
23. Minami K, Saito T, Narahara M, Tomita H, Kato H, Sugiyama H. 2005. Relationship between hepatic gene expression profiles and hepatotoxicity in five typical hepatotoxicant-administered rats. Toxicol Sci 87:296-305.
24. Mossmann T. 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
25. Nagaraj NS, Beckers S, Mensah JK, Waigel S, Vigneswaran N, Zacharias W. 2006. Cigarette smoke condensate induces cytochromes P450 and aldo-keto reductases in oral cancer cells. Toxicol Lett 165:182-194.
26. Nagy B, Ferrer A, Larramendy ML, Galimberti S, Aalto Y, Casas S, Vilpo J, Ruutu T, Vettenranta K, Franssila K, Knuutila S. 2003. Lymphotoxin beta expression is high in chronic lymphocytic leukemia but low in small lymphocytic lymphoma: A quantitative real-time reverse transcriptase polymerase chain reaction analysis. Haematologica 88:654-658.
27. Park GH, Choe J, Choo HJ, Park YG, Sohn J, Kim MK. 2002. Genome-wide expression profiling of 8-chloroadenosine- and 8-chloro-cAMP-treated human neuroblastoma cells using radioactive human cDNA microarray. Exp Mol Med 34:184-193.
28. Roman J, Ritzenthaler JD, Gil-Acosta A, Rivera HN, Roser-Page S. 2004. Nicotine and fibronectin expression in lung fibroblasts: Implications for tobacco-related lung tissue remodeling. FASEB J 18:1436-1438
29. Sasco AJ, Secretan MB, Straif K. 2004. Tobacco smoking and cancer: A brief review of recent epidemiological evidence. Lung Cancer 45 (Suppl 2):S3-S9.
30. Sohn SH, Kim IK, Kim KN, Kim HW, Seo SH, Lee SH, Kim YR, Lee EI, Kim MK. 2006. Genotoxicity biological effects of smoking-induced environmental toxicity. Mol Cell Toxicol 2:202-211.
31. Spivack SD, Hurteau GJ, Fasco MJ, Kaminsky LS. 2003. Phase I and II carcinogen metabolism gene expression in human lung tissue and tumors. Clin Cancer Res 9:6002-6011.
32. Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH III, Becker KG, Ko MSH. 2000. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Proc Natl Acad Sci USA 97:9127-9132.
33. Vawter MP, Barrett T, Cheadle C, Sokolov BP, Wood WH, Donovan DM III, Webster M, Freed WJ, Becker KG. 2001. Application of cDNA microarrays to examine gene expression differences in schizophrenia. Brain Res Bull 55:641-650.
34. Vineis P, Alavanja M, Buffler P, Fontham E, Franceschi S, Gao YT, Gupta PC, Hackshaw A, Matos E, Samet J, Sitas F, Smith J, Stayner L, Straif K, Thun MJ, Wichmann HE, Wu AH, Zaridze D, Peto R, Doll R. 2004. Tobacco and cancer: Recent epidemiological evidence. J Natl Cancer Inst 96:99-106.
35. Wang Y, Barbacioru C, Hyland F, Xiao W, Hunkapiller KL, Blake J, Chan F, Gonzalez C, Zhang L, Samaha RR. 2006. Large scale real-time PCR validation on gene expression measurements from two commercial long-oligonucleotide microarrays. BMC Genomics 7:59.
36. Zhang T, Lu H, Shang X, Tian Y, Zheng C, Wang S, Cheng H, Zhou R. 2006. Nicotine prevents the apoptosis induced by menadione in human lung cancer cells. Biochem Biophys Res Commun 342:928-934.