Role of vitamin E in immune system

Journal of Clinical Biochemistry and Nutrition

Volumn 34, Issue 3, 2004, Pages 97-109

  Moriguchi, Satoru ^a   Kaneyasu, Mayumi ^a  

^a YAMAGUCHI PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Aging; AIDS; Allergy; T cell differentiation; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AGING; ALLERGY; ALPHA TOCOPHEROL DEFICIENCY; AUTOIMMUNE DISEASE; CELL DIFFERENTIATION; CELLULAR IMMUNITY; HUMAN; IMMUNE SYSTEM; IMMUNITY; IMMUNOMODULATION; NONHUMAN; REVIEW; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; THYMUS; VITAMIN SUPPLEMENTATION;

EID: 4744359038     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.34.97     Document Type: Review

References (58)

1. Meydani, S.N., Barklund, M.P., Liu, S., Meydani, M., Miller, R., Cannon, J., Morrow, F., Rocklin, R., and Blumberg, J.: Vitamin E supplementation enhances cell-mediated immunity in healthy elderly. Am. J. Clin. Nutr., 52, 557-563, 1990.
2. 2 synthesis and enhances the immune response in aged mice. Mech. Age. Dev., 34, 191-201, 1986.
3. Machlin, L.: Vitamin E and prostaglandins, in Tocopherol, Oxygen, and Biomembranes, ed. by de Duve, C. and Hayaishi, O., Elsevier/North-Holland Biomedical Press, Amsterdam, pp. 208-215, 1978.
4. Sharmanov, A.T., Aidarkhanov, B.B., and Kurmangaliev, S.M.: Effect of vitamin E on oxidative metabolism of macrophages. Bull. Exp. Biol. Med., 101, 723-725, 1986.
5. Moriguchi, S., Kobayashi, N., and Kishino, Y.: Effects of vitamin E deficiency on the functions of splenic lymphocytes and alveolar macrophages. J. Nutr. Sci. Vitaminol., 35, 419-430, 1989.
6. Sharp, A.K. and Colston, M.J.: Elevated macrophage activity in nude mice. Exp. Cell Biol., 52, 44-47, 1984.
7. Moriguchi, S. and Muraga, M.: Vitamin E and immunity, in Vitamins and Hormones, Vol. 59, ed. by Litwack, G., Academic Press, New York, pp.305-336, 2000.
8. Baehner, R.L., Boxer, L.A., Allen, L.M., and Davis, J.: Autoxidation as a basis for altered function by polymorphonuclear leukocytes. Blood, 50, 327-335, 1977.
9. Goodwin, J.S., Messner, R.P., and Peake, G.T.: Prostaglandin suppression of mitogen-stimulated lymphocytes in vitro. Changes with mitogen dose and preincubation. J. Clin. Invest., 72, 753-760, 1978.
10. Segman, W.E., Gindhart, TD., Blackman, M.A., Dalal, B., Talal, N., and Werb, Z.: Suppression of natural killing in vitro by monocytes and polymorphonuclear leukocytes. J. Clin. Invest., 69, 876-888, 1982.
11. El-Hag, A., Lipsky, P.E., Bennett, M., and Clark, R.A.: Immunomodulation by neutrophil myeloperoxidase and hydrogen peroxide: Differential susceptibility of human lymphocyte function. J. Immunol., 9, 3420-3426, 1986.
12. Moriguchi, S., Kobayashi, N., and Kishino, Y.: High dietary intakes of vitamin E and cellular immune functions in rats. J. Nutr., 120, 1096-1102, 1990.
13. Fidler, I.J.: Macrophages and metastasis - A biological approach to cancer therapy. Cancer Res., 45, 4714-4726, 1985.
14. Nathan, C.F.: Secretory products of macrophages. Clin. Invest., 79, 319-326, 1987.
15. 2 production by macrophages. Nutr. Cancer, 20, 205-214, 1993.
16. Oonishi, K., Moriguchi, S., and Kishino, Y.: The role of macrophages in increased mitogen response of rat splenic lymphocytes following in vitro incubation with vitamin E. J. Nutr. Sci. Vitaminol., 41, 445-453, 1995.
17. Lemke, H. and Opitz, H.G.: Function of 2-mercaptoethanol as a macrophage substitute in the primary immune response in vitro. J. Immunol., 117, 388-395, 1976.
18. Takeda, T., Hosokawa, M., Takeshita, S., Irino, M., Matsushita, T., Tomita, Y., Yasuhira, K., Hamamoto, H., Shimizu, K., Ishii, M., and Yamamuro, T.: A new murine model of accelerated senescence. Mech. Ageing Dev., 17, 183-194, 1981.
19. Umezawa, M., Hamada, K., Naiki, H., Chen, W.H., Hosokawa, M., Hosono, M., Hosokawa, T., and Takeda, T.: Effects of dietary restriction on age-related immune dysfunction in the senescence accelerated mouse (SAM). J. Nutr., 120, 1393-1400, 1990.
20. Muraga, M., Umegaki, K., Yamamoto, S., and Moriguchi, S.: Decreased mitogen response of splenocytes in senescence accelerated mice (SAM-P1) is not restored by high vitamin E diet. Nutr. Res., 19, 1393-1400, 1999.
21. Okamoto, K. and Aoki, K.: Development of a strain of spontaneously hypertensive rats. Jpn. Circ. J., 27, 287-293, 1963.
22. Takeichi, N., Suzuki, K., and Kobayashi, H.: Characterization of immunological depression in spontaneously hypertensive rats. Eur. J. Immunol., 11, 483-487, 1981.
23. Moriguchi, S., Maekawa, K., Miwa, H., and Kishino, Y.: Effect of vitamin E supplementation on cellular immune functions decreased with aging in spontaneously hypertensive rats. Nutr. Res., 13, 1039-1051, 1993.
24. Sharp, A.K. and Colston, M.J.: Elevated macrophage activity in nude mice. Exp. Cell Biol., 52, 44-47, 1984.
25. Takeichi, N., Ba, D., and Kobayashi, H.: Natural cytotoxic autoantibody against thymocytes in spontaneously hypertensive rats. Cell Immunol., 60, 181-190, 1981.
26. Moriguchi, S., Maekawa, K., Okamoto, M., Oonishi, K., and Kishino, Y.: Vitamin E prevents the decrease of cellular immune function with aging in spontaneously hypertensive rats. Nutr. Res., 15, 401-414. 1995.
27. Landmark, K.: Vitamin E is beneficial for the immune system in the elderly. Tidsskr. Nor Laegeforen, 118, 4403-4404, 1998.
28. Meydani, S.N. and Beharka, A.A.: Recent developments in vitamin E and immune response. Nutr. Rev., 56, S49-58, 1998.
29. Goodwin, J.S. and Garry, P.J.: Relationship between megadose vitamin supplementation and immunological function in a healthy elderly population. Clin. Exp. Immunol., 51, 647-653, 1983.
30. Chavance, M., Brubacher, G., Herbeth, B., Vernhes, G., Mikstachi, T., Dete, F., Fournier, C., and Janot, C.: Imnmnological and nutritional status among the elderly, in Nutrition, Immunity and Illness in the Elderly, ed. by Chandra, R.K., Pergamon Press, New York, pp.137-142, 1985.
31. Payette, H., Rpla-Pleszczynski, M., and Bhadirian, P.: Nutrition factors in relation to cellular and regulatory immune variables in a free-living elderly population. Am. J. Clin. Nutr, 52, 927-932, 1990.
32. Nagel, J.E., Chopra, R.K., Chrest, F.J., McCoy, M.T., Schneider, E.L., Holbrook, N.J., and Adler, W.H.: Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors. J. Clin. Invest., 81, 1096-1102, 1988.
33. De Waart, F.G., Portengen, L., Doekes, G., Verwaal, C.J., and Kok, F.J.: Effect of 3 months' vitamin E supplementation on indices of the cellular and humoral immune response in elderly subjects. Br. J. Nutr., 78, 761-774, 1997.
34. De la Fuente, M., Ferrnandez, M.D., Burgus, M.S., Soler, A., Prieto, A., and Miquel, J.: Immune function in aged women is improved by ingestion of vitamins C and E. Can. J. Physiol. Pharmacol. 76, 373-380, 1998.
35. Watanabe, Y., Muraga, M., and Moriguchi, S.: Epidemiological study on the relationship between decreased cellular immunity and nitric oxide (NO) in the aged. Rep. Res. Comm. Essent. Amino Acids, 158, 39-44, 2000 (in Japanese).
36. Beharka, A.A., Wu, D., Ham, S.N., and Meydani, S.N.: Macrophage prostaglandin production contributes to the age-associated decrease in T cell function which is reversed by the dietary antioxidant vitamin E. Mech. Ageing Dev., 93, 59-77, 1997.
37. Fu, Y. and Blankenhorn, E.P.: Nitric oxide-induced anti-mitogenic effects in high and low responder rat strains. J. Immunol., 148, 2217-2222, 1992.
38. Moriguchi, S., Miwa, H., Okamura, M., Maekawa, K., Kishino, Y., and Maeda, K.: Vitamin E is an important factor in T cell differentiation in thymus of F344 rats. J. Nutr. Sci. Vitaminol., 39, 451-463, 1993.
39. Rappaport, R.S. and Dodge, G.R.: Prostaglandin E inhibits the production of human interleukin 2. J. Exp. Med., 155, 943-948, 1982.
40. Eshel, I., Savion, N., and Shoham, J.: Analysis of thymic stromal cell subpopulation grown in vitro on extracellular matrix in defined medium. II. Cytokine activities in murine thymic epithelial and mesenchymal culture supernatants. J. Immunol., 144, 1563-1570, 1990.
41. Moriguchi, S. and Itoh, T: Vitamin E enhances T cell differentiation through increased epithelial cell function in rats thymus. Nutr. Res., 17, 873-883, 1997.
42. - thymocytes in vitro. J. Exp. Med., 179, 2027-2031, 1994.
43. Schreck, R., Rieber, P., and Baeuerle, P.A.: Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J., 10, 2247-2258, 1991.
44. Staal, F.J., Roederer, M., Herzenberg, L.A., and Herzenberg, L.A.: Intracellular thiols regulate activation of nuclear factor κB and transcription of human immunodeficiency virus. Proc. Natl. Acad. Sci. USA, 87, 9943-9947, 1990.
45. Odeleye, O.E. and Watson, R.R.: The potential role of vitamin E in the treatment of immunologic abnormalities during acquired immune deficiency syndrome. Prog. Food Nutr. Sci., 15, 1-19, 1991.
46. Moseson, M., Zeleniuch-Jacquotte, A., Belsito, D.V., Shore, R.E., Marmor, M., and Pastermack, B.: The potential role of nutritional factors in the induction of immunologic abnormalities in HIV-positive homosexual men. J. Acquir. Immune Defic. Syndr., 2, 235-247, 1989.
47. Morse, III, H.C., Chattopadhyay, S.K., Makino, M., Fredrickson, T.N., Hugin, W., and Hartley, J.W.: Retrovirus-induced immunodeficiency in the mouse: MAIDS as a model for AIDS. AIDS, 6, 607-621, 1992.
48. Portnoi, D., Staal, A.M., Schwartz, D., Merigan, T.C., Herzenberg, L.A., and Basham, T.: Zidovudine (azido dideoxythymidine) inhibits characteristic early alterations of lymphoid cell population in retrovirus-induced murine AIDS. J. Immunol., 144, 1705-1710, 1990.
49. Lenardo, M.J. and Baltimore, D.: NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control. Cell, 58, 227-229, 1989.
50. Hamada, M., Yamamoto, S., Kishino, Y., and Moriguchi, S.: Vitamin E suppresses the development of murine AIDS through the inhibition of nuclear-KB expression. Nutr. Res., 20, 1163-1171, 2000.
51. Zheng, K.-C., Adjei, A., Shinjo, M., Shinjo, S., Todoriki, H., and Arizumi, M.: Effect of dietary vitamin E supplementation on murine nasal allergy. Am. J. Med. Sci., 318, 49-54, 1999.
52. Inagaki, N., Nagai, H., and Koda, A.: Effect of vitamin E on IgE antibody formation in mice. J. Pharm. Dyn., 7, 70-74, 1984.
53. Douillet, C., Bost, M., Accominotti, M., Borson-Chazot, F., and Ciavatti, M.: Effect of selenium and vitamin E supplementation on lipid abnormalities in plasma aorta, and adipose tissue of Zucker rats. Biol. Trace Elem. Res., 65, 221-236, 1998.
54. 2 on the release of chemical mediators from human peripheral leukocytes. Arerugi, 42, 1677-1682, 1993 (in Japanese).
55. Fogarty, A., Lewis, S., Weiss, S., and Britton, J.: Dietary vitamin E, IgE concentrations, and atopy. Lancet, 356, 1573-1574, 2000.
56. Weimann, B.J. and Hermann, D.: Inhibition of autoimmune deterioration in MRL/lpr mice by vitamin E. Int. J. Vitam. Nutr. Res., 69, 255-261, 1999.
57. Kuemmerie, N.B., Chan, W., Krieg, R.J., Jr., Norkus, E.P., Trachtman, H., and Chan, J.C.: Effects of fish oil and α-tocopherol in immunoglobulin A nephropathy in the rat. Pediatr. Res., 43, 791-797, 1998.
58. Bae, S.C., Kin, S.J., and Sung, M.K.: Impaired antioxidant status and decreased dietary intake of antioxidants in patients with systemic lupus erythematosus. Rheumatol. Int., 22, 238-243, 2002.